GSEA of Modules with highest Enrichment in SFARI Genes

#setwd('/afs/inf.ed.ac.uk/user/s17/s1725186/Documents/PhD-Models/FirstPUModel/RMarkdowns')

library(tidyverse) ; library(reshape2) ; library(glue) ; library(plotly) ; library(dendextend)
library(RColorBrewer) ; library(viridis) ; require(gridExtra) ; library(GGally)
library(knitr)
library(biomaRt)
library(clusterProfiler) ; library(ReactomePA) ; library(DOSE)

Load preprocessed dataset (preprocessing code in 19_10_14_data_preprocessing.Rmd) and clustering (pipeline in 19_10_21_WGCNA.Rmd)

# Gandal dataset
load('./../Data/preprocessed_data.RData')
datExpr = datExpr %>% data.frame
DE_info = DE_info %>% data.frame


# GO Neuronal annotations: regex 'neuron' in GO functional annotations and label the genes that make a match as neuronal
GO_annotations = read.csv('./../Data/genes_GO_annotations.csv')
GO_neuronal = GO_annotations %>% filter(grepl('neuron', go_term)) %>% 
              mutate('ID'=as.character(ensembl_gene_id)) %>% 
              dplyr::select(-ensembl_gene_id) %>% distinct(ID) %>%
              mutate('Neuronal'=1)


# SFARI Genes
SFARI_genes = read_csv('./../../../SFARI/Data/SFARI_genes_01-03-2020_w_ensembl_IDs.csv')
SFARI_genes = SFARI_genes[!duplicated(SFARI_genes$ID) & !is.na(SFARI_genes$ID),]


# Clusterings
clusterings = read_csv('./../Data/clusters.csv')


# Update DE_info with SFARI and Neuronal information
genes_info = DE_info %>% mutate('ID'=rownames(.)) %>% left_join(SFARI_genes, by='ID') %>% 
  mutate(`gene-score`=ifelse(is.na(`gene-score`), 'None', `gene-score`)) %>%
  left_join(GO_neuronal, by='ID') %>% left_join(clusterings, by='ID') %>%
  mutate(Neuronal=ifelse(is.na(Neuronal), 0, Neuronal)) %>%
  mutate(gene.score=ifelse(`gene-score`=='None' & Neuronal==1, 'Neuronal', `gene-score`), 
         significant=padj<0.05 & !is.na(padj))


clustering_selected = 'DynamicHybrid'
genes_info$Module = genes_info[,clustering_selected]

dataset = read.csv(paste0('./../Data/dataset_', clustering_selected, '.csv'))
dataset$Module = dataset[,clustering_selected]

# Correct SFARI Scores
dataset$gene.score = genes_info$gene.score

# GSEA Results
load('./../Data/GSEA.RData')


SFARI_colour_hue = function(r) {
  pal = c('#FF7631','#FFB100','#E8E328','#8CC83F','#62CCA6','#59B9C9','#b3b3b3','#808080','gray','#d9d9d9')[r]
}

rm(DE_info, GO_annotations, clusterings, getinfo, mart, dds, GO_neuronal)

Module-Diagnosis Correlation

plot_data = dataset %>% dplyr::select(Module, MTcor) %>% distinct

ggplotly(plot_data %>% ggplot(aes(reorder(Module, -MTcor), MTcor)) + geom_bar(stat='identity', fill = plot_data$Module) + theme_minimal() + 
         xlab('Modules')+ ylab('Module-Diagnosis Correlation') + geom_hline(yintercept =c(0.9, -0.9), color = 'gray', linetype = 'dashed') + 
         theme(axis.text.x = element_text(angle = 90, hjust = 1)))

top_modules = plot_data$Module[abs(plot_data$MTcor)>0.9]

cat(paste0('Top modules selected: ', paste(top_modules, collapse=', '),'\n'))

## Top modules selected: #00B9E3, #73B000, #EE8045, #84AD00

GSEA Results

KEGG

for(module in top_modules){
  df = enrichment_KEGG[[module]] %>% dplyr::select(ID, Description, setSize, NES, p.adjust, qvalues) %>% arrange(desc(NES)) %>% filter(NES>0)
  if(nrow(df)>0){
    print(kable(df, caption = paste0('Enriched terms for module ', module, ' (MTcor = ', round(dataset$MTcor[dataset$Module==module][1],2),')')))
    cat('\n') 
  } else cat(paste0('\nNo enrichment found for module ',module,'\n'))
}

Enriched terms for module #00B9E3 (MTcor = -0.93)

ID	Description	setSize	NES	p.adjust	qvalues
hsa00190	Oxidative phosphorylation	127	2.725585	0.0142895	0.0090437
hsa05016	Huntington disease	289	2.590995	0.0142895	0.0090437
hsa05012	Parkinson disease	235	2.558477	0.0142895	0.0090437
hsa04721	Synaptic vesicle cycle	70	2.390995	0.0142895	0.0090437
hsa04723	Retrograde endocannabinoid signaling	142	2.372331	0.0142895	0.0090437
hsa05010	Alzheimer disease	348	2.329095	0.0142895	0.0090437
hsa04260	Cardiac muscle contraction	79	2.291035	0.0142895	0.0090437
hsa04970	Salivary secretion	72	2.282914	0.0142895	0.0090437
hsa05033	Nicotine addiction	35	2.266381	0.0142895	0.0090437
hsa04720	Long-term potentiation	65	2.227201	0.0142895	0.0090437
hsa00020	Citrate cycle (TCA cycle)	29	2.222275	0.0142895	0.0090437
hsa04114	Oocyte meiosis	108	2.220302	0.0142895	0.0090437
hsa04728	Dopaminergic synapse	125	2.187980	0.0142895	0.0090437
hsa03050	Proteasome	43	2.178270	0.0142895	0.0090437
hsa04727	GABAergic synapse	82	2.167709	0.0142895	0.0090437
hsa05017	Spinocerebellar ataxia	124	2.147446	0.0142895	0.0090437
hsa04932	Non-alcoholic fatty liver disease (NAFLD)	139	2.146858	0.0142895	0.0090437
hsa04714	Thermogenesis	220	2.133993	0.0142895	0.0090437
hsa04713	Circadian entrainment	93	2.128740	0.0142895	0.0090437
hsa04961	Endocrine and other factor-regulated calcium reabsorption	48	2.127776	0.0142895	0.0090437
hsa04724	Glutamatergic synapse	108	2.091530	0.0142895	0.0090437
hsa05031	Amphetamine addiction	63	2.059674	0.0142895	0.0090437
hsa04740	Olfactory transduction	76	2.055744	0.0142895	0.0090437
hsa05032	Morphine addiction	85	2.031618	0.0142895	0.0090437
hsa01210	2-Oxocarboxylic acid metabolism	16	2.003497	0.0185904	0.0117657
hsa04020	Calcium signaling pathway	184	1.966258	0.0142895	0.0090437
hsa04070	Phosphatidylinositol signaling system	95	1.950537	0.0142895	0.0090437
hsa04929	GnRH secretion	60	1.939168	0.0142895	0.0090437
hsa04925	Aldosterone synthesis and secretion	91	1.937756	0.0142895	0.0090437
hsa04261	Adrenergic signaling in cardiomyocytes	141	1.909070	0.0142895	0.0090437
hsa04921	Oxytocin signaling pathway	149	1.894214	0.0142895	0.0090437
hsa04136	Autophagy - other	31	1.881438	0.0182086	0.0115241
hsa04750	Inflammatory mediator regulation of TRP channels	94	1.880734	0.0142895	0.0090437
hsa00430	Taurine and hypotaurine metabolism	10	1.868491	0.0333333	0.0210964
hsa04725	Cholinergic synapse	106	1.867310	0.0142895	0.0090437
hsa04971	Gastric acid secretion	70	1.847689	0.0177466	0.0112316
hsa04911	Insulin secretion	77	1.814558	0.0177466	0.0112316
hsa01230	Biosynthesis of amino acids	68	1.779597	0.0177466	0.0112316
hsa04910	Insulin signaling pathway	130	1.773621	0.0142895	0.0090437
hsa04962	Vasopressin-regulated water reabsorption	40	1.772690	0.0142895	0.0090437
hsa04966	Collecting duct acid secretion	23	1.769597	0.0281783	0.0178338
hsa01200	Carbon metabolism	109	1.762592	0.0142895	0.0090437
hsa04973	Carbohydrate digestion and absorption	34	1.729121	0.0276165	0.0174782
hsa04914	Progesterone-mediated oocyte maturation	82	1.708799	0.0261934	0.0165776
hsa05110	Vibrio cholerae infection	47	1.704891	0.0266368	0.0168582
hsa04930	Type II diabetes mellitus	40	1.693712	0.0275011	0.0174052
hsa04924	Renin secretion	64	1.675302	0.0264688	0.0167518
hsa05214	Glioma	72	1.662962	0.0287805	0.0182149
hsa00650	Butanoate metabolism	23	1.660218	0.0281783	0.0178338
hsa05014	Amyotrophic lateral sclerosis (ALS)	52	1.656965	0.0293698	0.0185879
hsa04912	GnRH signaling pathway	86	1.650970	0.0287805	0.0182149
hsa04972	Pancreatic secretion	72	1.646154	0.0287805	0.0182149
hsa00970	Aminoacyl-tRNA biosynthesis	44	1.644861	0.0231068	0.0146241
hsa04012	ErbB signaling pathway	82	1.640908	0.0287805	0.0182149
hsa04360	Axon guidance	179	1.625791	0.0142895	0.0090437
hsa04024	cAMP signaling pathway	192	1.618113	0.0142895	0.0090437
hsa04922	Glucagon signaling pathway	93	1.614376	0.0215552	0.0136421
hsa00250	Alanine, aspartate and glutamate metabolism	34	1.612569	0.0357580	0.0226309
hsa00620	Pyruvate metabolism	36	1.610817	0.0357514	0.0226267
hsa04960	Aldosterone-regulated sodium reabsorption	32	1.590688	0.0357580	0.0226309
hsa04150	mTOR signaling pathway	147	1.587515	0.0142895	0.0090437
hsa04120	Ubiquitin mediated proteolysis	135	1.578271	0.0177466	0.0112316
hsa04140	Autophagy - animal	131	1.546534	0.0142895	0.0090437
hsa04978	Mineral absorption	48	1.540175	0.0383349	0.0242618
hsa04726	Serotonergic synapse	102	1.532754	0.0215552	0.0136421
hsa04014	Ras signaling pathway	209	1.514586	0.0213190	0.0134926
hsa04371	Apelin signaling pathway	127	1.510024	0.0256672	0.0162445
hsa04660	T cell receptor signaling pathway	87	1.469408	0.0444462	0.0281296
hsa04071	Sphingolipid signaling pathway	113	1.457265	0.0357580	0.0226309
hsa04022	cGMP-PKG signaling pathway	157	1.435193	0.0427310	0.0270440
hsa04080	Neuroactive ligand-receptor interaction	254	1.385600	0.0439353	0.0278062

Enriched terms for module #73B000 (MTcor = 0.94)

ID	Description	setSize	NES	p.adjust	qvalues
hsa05322	Systemic lupus erythematosus	108	3.169288	0.0117509	0.0072829
hsa05034	Alcoholism	165	2.474094	0.0117509	0.0072829
hsa04061	Viral protein interaction with cytokine and cytokine receptor	52	2.309397	0.0117509	0.0072829
hsa05202	Transcriptional misregulation in cancer	163	2.223024	0.0117509	0.0072829
hsa05144	Malaria	39	2.172061	0.0117509	0.0072829
hsa04392	Hippo signaling pathway - multiple species	26	2.149780	0.0117509	0.0072829
hsa05150	Staphylococcus aureus infection	49	2.132591	0.0117509	0.0072829
hsa05321	Inflammatory bowel disease (IBD)	47	2.125786	0.0117509	0.0072829
hsa04064	NF-kappa B signaling pathway	89	2.090723	0.0117509	0.0072829
hsa04060	Cytokine-cytokine receptor interaction	170	2.053668	0.0117509	0.0072829
hsa05134	Legionellosis	52	1.967451	0.0117509	0.0072829
hsa04612	Antigen processing and presentation	59	1.964714	0.0117509	0.0072829
hsa05203	Viral carcinogenesis	188	1.955215	0.0117509	0.0072829
hsa04977	Vitamin digestion and absorption	18	1.947716	0.0190273	0.0117926
hsa04610	Complement and coagulation cascades	61	1.879219	0.0190273	0.0117926
hsa05416	Viral myocarditis	52	1.858729	0.0117509	0.0072829
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	19	1.858662	0.0190273	0.0117926
hsa04520	Adherens junction	70	1.853247	0.0117509	0.0072829
hsa05145	Toxoplasmosis	104	1.817225	0.0117509	0.0072829
hsa04330	Notch signaling pathway	51	1.813349	0.0117509	0.0072829
hsa04512	ECM-receptor interaction	80	1.781208	0.0117509	0.0072829
hsa05206	MicroRNAs in cancer	155	1.775663	0.0117509	0.0072829
hsa05205	Proteoglycans in cancer	190	1.775018	0.0117509	0.0072829
hsa05131	Shigellosis	226	1.749792	0.0117509	0.0072829
hsa04510	Focal adhesion	192	1.737613	0.0117509	0.0072829
hsa04350	TGF-beta signaling pathway	86	1.714838	0.0190273	0.0117926
hsa05332	Graft-versus-host disease	26	1.709331	0.0241808	0.0149866
hsa05340	Primary immunodeficiency	25	1.705382	0.0301940	0.0187135
hsa05330	Allograft rejection	24	1.700455	0.0190273	0.0117926
hsa05168	Herpes simplex virus 1 infection	446	1.673237	0.0117509	0.0072829
hsa05320	Autoimmune thyroid disease	28	1.669109	0.0455375	0.0282229
hsa04672	Intestinal immune network for IgA production	32	1.666816	0.0241808	0.0149866
hsa04621	NOD-like receptor signaling pathway	148	1.636858	0.0117509	0.0072829
hsa04514	Cell adhesion molecules (CAMs)	123	1.565910	0.0117509	0.0072829
hsa04659	Th17 cell differentiation	88	1.564444	0.0302873	0.0187713
hsa04670	Leukocyte transendothelial migration	97	1.561877	0.0243206	0.0150733
hsa04810	Regulation of actin cytoskeleton	197	1.561233	0.0190273	0.0117926
hsa04668	TNF signaling pathway	103	1.545790	0.0190273	0.0117926
hsa00514	Other types of O-glycan biosynthesis	46	1.532010	0.0455375	0.0282229
hsa04151	PI3K-Akt signaling pathway	308	1.497327	0.0241808	0.0149866
hsa05222	Small cell lung cancer	89	1.472050	0.0455375	0.0282229
hsa04630	JAK-STAT signaling pathway	113	1.458875	0.0455375	0.0282229
hsa05130	Pathogenic Escherichia coli infection	176	1.454159	0.0245707	0.0152283
hsa04390	Hippo signaling pathway	148	1.444705	0.0359616	0.0222880
hsa04217	Necroptosis	134	1.439714	0.0412331	0.0255552
hsa05200	Pathways in cancer	479	1.417741	0.0117509	0.0072829
hsa05165	Human papillomavirus infection	300	1.416952	0.0348186	0.0215797
hsa05163	Human cytomegalovirus infection	199	1.370276	0.0455375	0.0282229
hsa05166	Human T-cell leukemia virus 1 infection	197	1.344666	0.0496712	0.0307849

Enriched terms for module #EE8045 (MTcor = 0.93)

ID	Description	setSize	NES	p.adjust	qvalues
hsa05322	Systemic lupus erythematosus	108	3.121824	0.0140101	0.0083156
hsa05168	Herpes simplex virus 1 infection	446	2.543998	0.0140101	0.0083156
hsa05202	Transcriptional misregulation in cancer	163	2.476173	0.0140101	0.0083156
hsa05150	Staphylococcus aureus infection	49	2.471518	0.0140101	0.0083156
hsa05034	Alcoholism	165	2.465300	0.0140101	0.0083156
hsa04064	NF-kappa B signaling pathway	89	2.305115	0.0140101	0.0083156
hsa04610	Complement and coagulation cascades	61	2.192555	0.0140101	0.0083156
hsa05321	Inflammatory bowel disease (IBD)	47	2.156191	0.0140101	0.0083156
hsa04061	Viral protein interaction with cytokine and cytokine receptor	52	2.120471	0.0140101	0.0083156
hsa05320	Autoimmune thyroid disease	28	2.092993	0.0140101	0.0083156
hsa04392	Hippo signaling pathway - multiple species	26	2.086178	0.0140101	0.0083156
hsa05416	Viral myocarditis	52	2.083955	0.0140101	0.0083156
hsa05134	Legionellosis	52	2.079065	0.0140101	0.0083156
hsa05330	Allograft rejection	24	2.036625	0.0140101	0.0083156
hsa05203	Viral carcinogenesis	188	2.002009	0.0140101	0.0083156
hsa05332	Graft-versus-host disease	26	1.983489	0.0140101	0.0083156
hsa04672	Intestinal immune network for IgA production	32	1.982276	0.0140101	0.0083156
hsa04060	Cytokine-cytokine receptor interaction	170	1.974136	0.0140101	0.0083156
hsa04640	Hematopoietic cell lineage	66	1.926270	0.0140101	0.0083156
hsa05140	Leishmaniasis	67	1.923574	0.0140101	0.0083156
hsa05340	Primary immunodeficiency	25	1.902833	0.0140101	0.0083156
hsa04612	Antigen processing and presentation	59	1.873119	0.0140101	0.0083156
hsa05310	Asthma	14	1.863082	0.0140101	0.0083156
hsa04658	Th1 and Th2 cell differentiation	75	1.819414	0.0140101	0.0083156
hsa05144	Malaria	39	1.814599	0.0203551	0.0120816
hsa04621	NOD-like receptor signaling pathway	148	1.808902	0.0140101	0.0083156
hsa04670	Leukocyte transendothelial migration	97	1.807719	0.0140101	0.0083156
hsa05145	Toxoplasmosis	104	1.790727	0.0140101	0.0083156
hsa00310	Lysine degradation	58	1.773076	0.0238857	0.0141771
hsa04611	Platelet activation	114	1.747916	0.0140101	0.0083156
hsa05130	Pathogenic Escherichia coli infection	176	1.688804	0.0140101	0.0083156
hsa04520	Adherens junction	70	1.674426	0.0238857	0.0141771
hsa04380	Osteoclast differentiation	114	1.661062	0.0151515	0.0089930
hsa04659	Th17 cell differentiation	88	1.659774	0.0140101	0.0083156
hsa04512	ECM-receptor interaction	80	1.658362	0.0151594	0.0089977
hsa04350	TGF-beta signaling pathway	86	1.654834	0.0151594	0.0089977
hsa05205	Proteoglycans in cancer	190	1.621493	0.0140101	0.0083156
hsa04510	Focal adhesion	192	1.620985	0.0140101	0.0083156
hsa05206	MicroRNAs in cancer	155	1.603931	0.0140101	0.0083156
hsa05131	Shigellosis	226	1.594731	0.0140101	0.0083156
hsa04810	Regulation of actin cytoskeleton	197	1.572728	0.0140101	0.0083156
hsa04668	TNF signaling pathway	103	1.524116	0.0321654	0.0190915
hsa05167	Kaposi sarcoma-associated herpesvirus infection	166	1.495412	0.0221601	0.0131529
hsa05222	Small cell lung cancer	89	1.478848	0.0497166	0.0295088
hsa04151	PI3K-Akt signaling pathway	308	1.448583	0.0186492	0.0110691
hsa03040	Spliceosome	130	1.447219	0.0360264	0.0213831
hsa05200	Pathways in cancer	479	1.441772	0.0140101	0.0083156
hsa05135	Yersinia infection	114	1.439091	0.0450000	0.0267093

Enriched terms for module #84AD00 (MTcor = -0.93)

ID	Description	setSize	NES	p.adjust	qvalues
hsa00190	Oxidative phosphorylation	127	2.984700	0.0149748	0.0097229
hsa05016	Huntington disease	289	2.681127	0.0149748	0.0097229
hsa00020	Citrate cycle (TCA cycle)	29	2.617023	0.0149748	0.0097229
hsa05012	Parkinson disease	235	2.586621	0.0149748	0.0097229
hsa04260	Cardiac muscle contraction	79	2.357500	0.0149748	0.0097229
hsa04721	Synaptic vesicle cycle	70	2.315254	0.0149748	0.0097229
hsa05010	Alzheimer disease	348	2.305927	0.0149748	0.0097229
hsa03050	Proteasome	43	2.256555	0.0149748	0.0097229
hsa04714	Thermogenesis	220	2.236098	0.0149748	0.0097229
hsa04932	Non-alcoholic fatty liver disease (NAFLD)	139	2.187360	0.0149748	0.0097229
hsa01200	Carbon metabolism	109	2.162344	0.0149748	0.0097229
hsa01210	2-Oxocarboxylic acid metabolism	16	2.143368	0.0149748	0.0097229
hsa00650	Butanoate metabolism	23	2.105636	0.0149748	0.0097229
hsa04723	Retrograde endocannabinoid signaling	142	2.104901	0.0149748	0.0097229
hsa04728	Dopaminergic synapse	125	2.030861	0.0149748	0.0097229
hsa04961	Endocrine and other factor-regulated calcium reabsorption	48	2.023331	0.0149748	0.0097229
hsa00620	Pyruvate metabolism	36	2.019126	0.0149748	0.0097229
hsa05017	Spinocerebellar ataxia	124	1.993816	0.0149748	0.0097229
hsa01230	Biosynthesis of amino acids	68	1.991617	0.0149748	0.0097229
hsa04929	GnRH secretion	60	1.972337	0.0149748	0.0097229
hsa00970	Aminoacyl-tRNA biosynthesis	44	1.943065	0.0212745	0.0138132
hsa04910	Insulin signaling pathway	130	1.938894	0.0149748	0.0097229
hsa04925	Aldosterone synthesis and secretion	91	1.935218	0.0149748	0.0097229
hsa04740	Olfactory transduction	76	1.931878	0.0212745	0.0138132
hsa04930	Type II diabetes mellitus	40	1.906107	0.0149748	0.0097229
hsa04727	GABAergic synapse	82	1.893952	0.0149748	0.0097229
hsa04261	Adrenergic signaling in cardiomyocytes	141	1.880492	0.0149748	0.0097229
hsa04136	Autophagy - other	31	1.857815	0.0149748	0.0097229
hsa04970	Salivary secretion	72	1.856238	0.0212745	0.0138132
hsa00250	Alanine, aspartate and glutamate metabolism	34	1.849277	0.0149748	0.0097229
hsa00010	Glycolysis / Gluconeogenesis	54	1.848296	0.0149748	0.0097229
hsa05230	Central carbon metabolism in cancer	64	1.817534	0.0212745	0.0138132
hsa04922	Glucagon signaling pathway	93	1.808411	0.0212745	0.0138132
hsa04962	Vasopressin-regulated water reabsorption	40	1.792405	0.0287017	0.0186356
hsa04114	Oocyte meiosis	108	1.784072	0.0149748	0.0097229
hsa04966	Collecting duct acid secretion	23	1.783771	0.0212745	0.0138132
hsa04720	Long-term potentiation	65	1.770606	0.0212745	0.0138132
hsa04070	Phosphatidylinositol signaling system	95	1.754164	0.0212745	0.0138132
hsa04750	Inflammatory mediator regulation of TRP channels	94	1.744438	0.0212745	0.0138132
hsa05032	Morphine addiction	85	1.719339	0.0280815	0.0182330
hsa04020	Calcium signaling pathway	184	1.696421	0.0212745	0.0138132
hsa00640	Propanoate metabolism	32	1.684396	0.0280815	0.0182330
hsa04973	Carbohydrate digestion and absorption	34	1.683316	0.0329560	0.0213979
hsa04971	Gastric acid secretion	70	1.681012	0.0329560	0.0213979
hsa04960	Aldosterone-regulated sodium reabsorption	32	1.676416	0.0280815	0.0182330
hsa04211	Longevity regulating pathway	84	1.668980	0.0280815	0.0182330
hsa04911	Insulin secretion	77	1.654238	0.0329560	0.0213979
hsa05031	Amphetamine addiction	63	1.622657	0.0388357	0.0252155
hsa04912	GnRH signaling pathway	86	1.611412	0.0329560	0.0213979
hsa04725	Cholinergic synapse	106	1.610910	0.0212745	0.0138132
hsa04713	Circadian entrainment	93	1.605346	0.0329560	0.0213979
hsa05214	Glioma	72	1.595373	0.0498834	0.0323887
hsa04152	AMPK signaling pathway	112	1.593264	0.0212745	0.0138132
hsa04921	Oxytocin signaling pathway	149	1.591210	0.0329560	0.0213979
hsa04140	Autophagy - animal	131	1.588714	0.0430699	0.0279647
hsa04724	Glutamatergic synapse	108	1.580104	0.0280815	0.0182330
hsa04137	Mitophagy - animal	66	1.576242	0.0440329	0.0285900
hsa04146	Peroxisome	76	1.547012	0.0440329	0.0285900
hsa04144	Endocytosis	240	1.492803	0.0212745	0.0138132
hsa04150	mTOR signaling pathway	147	1.483418	0.0440329	0.0285900

rm(df)

Reactome

for(module in top_modules){
  df = enrichment_Reactome[[module]] %>% dplyr::select(ID, Description, setSize, NES, p.adjust, qvalues) %>% arrange(desc(NES)) %>% filter(NES>0)
  if(nrow(df)>0){
    print(kable(df, caption = paste0('Enriched terms for module ', module, ' (MTcor = ', round(dataset$MTcor[dataset$Module==module][1],2),')')))
    cat('\n') 
  } else cat(paste0('\nNo enrichment found for module ',module,'\n'))
}

Enriched terms for module #00B9E3 (MTcor = -0.93)

ID	Description	setSize	NES	p.adjust	qvalues
R-HSA-163200	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	122	2.776410	0.0178724	0.0120179
R-HSA-1428517	The citric acid (TCA) cycle and respiratory electron transport	170	2.728433	0.0178724	0.0120179
R-HSA-611105	Respiratory electron transport	100	2.715462	0.0178724	0.0120179
R-HSA-112316	Neuronal System	379	2.651142	0.0178724	0.0120179
R-HSA-112315	Transmission across Chemical Synapses	245	2.574492	0.0178724	0.0120179
R-HSA-5576892	Phase 0 - rapid depolarisation	45	2.562846	0.0178724	0.0120179
R-HSA-1296072	Voltage gated Potassium channels	40	2.562391	0.0178724	0.0120179
R-HSA-180024	DARPP-32 events	25	2.561405	0.0178724	0.0120179
R-HSA-399719	Trafficking of AMPA receptors	30	2.551657	0.0178724	0.0120179
R-HSA-399721	Glutamate binding, activation of AMPA receptors and synaptic plasticity	30	2.551657	0.0178724	0.0120179
R-HSA-112314	Neurotransmitter receptors and postsynaptic signal transmission	184	2.509965	0.0178724	0.0120179
R-HSA-6799198	Complex I biogenesis	55	2.489791	0.0178724	0.0120179
R-HSA-442755	Activation of NMDA receptors and postsynaptic events	84	2.423144	0.0178724	0.0120179
R-HSA-438066	Unblocking of NMDA receptors, glutamate binding and activation	22	2.413535	0.0178724	0.0120179
R-HSA-445095	Interaction between L1 and Ankyrins	29	2.408084	0.0178724	0.0120179
R-HSA-442982	Ras activation upon Ca2+ influx through NMDA receptor	21	2.381275	0.0178724	0.0120179
R-HSA-9620244	Long-term potentiation	24	2.352041	0.0178724	0.0120179
R-HSA-5682910	LGI-ADAM interactions	14	2.335524	0.0178724	0.0120179
R-HSA-9617324	Negative regulation of NMDA receptor-mediated neuronal transmission	22	2.330838	0.0178724	0.0120179
R-HSA-416993	Trafficking of GluR2-containing AMPA receptors	16	2.324380	0.0178724	0.0120179
R-HSA-438064	Post NMDA receptor activation events	73	2.321122	0.0178724	0.0120179
R-HSA-6794362	Protein-protein interactions at synapses	87	2.291878	0.0178724	0.0120179
R-HSA-111933	Calmodulin induced events	35	2.281160	0.0178724	0.0120179
R-HSA-111997	CaM pathway	35	2.281160	0.0178724	0.0120179
R-HSA-1489509	DAG and IP3 signaling	41	2.276476	0.0178724	0.0120179
R-HSA-8849932	Synaptic adhesion-like molecules	21	2.258640	0.0178724	0.0120179
R-HSA-1296071	Potassium Channels	92	2.229322	0.0178724	0.0120179
R-HSA-168799	Neurotoxicity of clostridium toxins	10	2.217107	0.0178724	0.0120179
R-HSA-5339562	Uptake and actions of bacterial toxins	30	2.208915	0.0178724	0.0120179
R-HSA-442742	CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	29	2.207101	0.0178724	0.0120179
R-HSA-5576891	Cardiac conduction	131	2.202644	0.0178724	0.0120179
R-HSA-111996	Ca-dependent events	37	2.201295	0.0178724	0.0120179
R-HSA-888590	GABA synthesis, release, reuptake and degradation	19	2.190853	0.0178724	0.0120179
R-HSA-442720	CREB1 phosphorylation through the activation of Adenylate Cyclase	13	2.190629	0.0178724	0.0120179
R-HSA-111885	Opioid Signalling	86	2.187655	0.0178724	0.0120179
R-HSA-1236978	Cross-presentation of soluble exogenous antigens (endosomes)	47	2.171698	0.0178724	0.0120179
R-HSA-210500	Glutamate Neurotransmitter Release Cycle	24	2.165354	0.0178724	0.0120179
R-HSA-1168372	Downstream signaling events of B Cell Receptor (BCR)	81	2.165205	0.0178724	0.0120179
R-HSA-163615	PKA activation	18	2.157031	0.0178724	0.0120179
R-HSA-69052	Switching of origins to a post-replicative state	87	2.152307	0.0178724	0.0120179
R-HSA-68867	Assembly of the pre-replicative complex	65	2.151911	0.0178724	0.0120179
R-HSA-68827	CDT1 association with the CDC6:ORC:origin complex	57	2.146901	0.0178724	0.0120179
R-HSA-5578775	Ion homeostasis	53	2.141367	0.0178724	0.0120179
R-HSA-5610783	Degradation of GLI2 by the proteasome	57	2.130907	0.0178724	0.0120179
R-HSA-112310	Neurotransmitter release cycle	47	2.128431	0.0178724	0.0120179
R-HSA-71403	Citric acid cycle (TCA cycle)	22	2.124935	0.0178724	0.0120179
R-HSA-379716	Cytosolic tRNA aminoacylation	24	2.122526	0.0178724	0.0120179
R-HSA-8986944	Transcriptional Regulation by MECP2	61	2.114457	0.0178724	0.0120179
R-HSA-5610785	GLI3 is processed to GLI3R by the proteasome	57	2.098608	0.0178724	0.0120179
R-HSA-2454202	Fc epsilon receptor (FCERI) signaling	129	2.094788	0.0178724	0.0120179
R-HSA-5610780	Degradation of GLI1 by the proteasome	57	2.090762	0.0178724	0.0120179
R-HSA-68949	Orc1 removal from chromatin	69	2.087479	0.0178724	0.0120179
R-HSA-5676590	NIK–>noncanonical NF-kB signaling	56	2.078113	0.0178724	0.0120179
R-HSA-451306	Ionotropic activity of kainate receptors	12	2.076721	0.0178724	0.0120179
R-HSA-451308	Activation of Ca-permeable Kainate Receptor	12	2.076721	0.0178724	0.0120179
R-HSA-442729	CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	10	2.065971	0.0178724	0.0120179
R-HSA-111932	CaMK IV-mediated phosphorylation of CREB	12	2.057352	0.0178724	0.0120179
R-HSA-8949613	Cristae formation	31	2.044059	0.0178724	0.0120179
R-HSA-174084	Autodegradation of Cdh1 by Cdh1:APC/C	62	2.036369	0.0178724	0.0120179
R-HSA-174113	SCF-beta-TrCP mediated degradation of Emi1	53	2.034984	0.0178724	0.0120179
R-HSA-68689	CDC6 association with the ORC:origin complex	10	2.025660	0.0178724	0.0120179
R-HSA-5607761	Dectin-1 mediated noncanonical NF-kB signaling	57	2.023513	0.0178724	0.0120179
R-HSA-350562	Regulation of ornithine decarboxylase (ODC)	49	2.023146	0.0178724	0.0120179
R-HSA-8939902	Regulation of RUNX2 expression and activity	70	2.021219	0.0178724	0.0120179
R-HSA-6794361	Neurexins and neuroligins	56	2.020335	0.0178724	0.0120179
R-HSA-112043	PLC beta mediated events	50	2.017642	0.0178724	0.0120179
R-HSA-5607763	CLEC7A (Dectin-1) induces NFAT activation	13	2.015495	0.0215245	0.0144737
R-HSA-176408	Regulation of APC/C activators between G1/S and early anaphase	76	2.015234	0.0178724	0.0120179
R-HSA-212676	Dopamine Neurotransmitter Release Cycle	22	2.011941	0.0178724	0.0120179
R-HSA-5610787	Hedgehog ‘off’ state	108	2.004448	0.0178724	0.0120179
R-HSA-983705	Signaling by the B Cell Receptor (BCR)	107	2.001362	0.0178724	0.0120179
R-HSA-9604323	Negative regulation of NOTCH4 signaling	54	2.000729	0.0178724	0.0120179
R-HSA-69017	CDK-mediated phosphorylation and removal of Cdc6	69	1.998678	0.0178724	0.0120179
R-HSA-422356	Regulation of insulin secretion	73	1.994300	0.0178724	0.0120179
R-HSA-163210	Formation of ATP by chemiosmotic coupling	18	1.990580	0.0178724	0.0120179
R-HSA-8854050	FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	52	1.986354	0.0178724	0.0120179
R-HSA-112040	G-protein mediated events	51	1.982836	0.0178724	0.0120179
R-HSA-1268020	Mitochondrial protein import	63	1.982673	0.0178724	0.0120179
R-HSA-5673000	RAF activation	32	1.981718	0.0178724	0.0120179
R-HSA-9609736	Assembly and cell surface presentation of NMDA receptors	34	1.979062	0.0178724	0.0120179
R-HSA-2025928	Calcineurin activates NFAT	11	1.979021	0.0178724	0.0120179
R-HSA-180534	Vpu mediated degradation of CD4	50	1.976988	0.0178724	0.0120179
R-HSA-174184	Cdc20:Phospho-APC/C mediated degradation of Cyclin A	69	1.975008	0.0178724	0.0120179
R-HSA-177504	Retrograde neurotrophin signalling	14	1.972319	0.0178724	0.0120179
R-HSA-351202	Metabolism of polyamines	83	1.968965	0.0178724	0.0120179
R-HSA-174154	APC/C:Cdc20 mediated degradation of Securin	64	1.968879	0.0207406	0.0139466
R-HSA-111931	PKA-mediated phosphorylation of CREB	20	1.964091	0.0178724	0.0120179
R-HSA-180585	Vif-mediated degradation of APOBEC3G	52	1.960509	0.0178724	0.0120179
R-HSA-169911	Regulation of Apoptosis	51	1.956624	0.0178724	0.0120179
R-HSA-179419	APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	70	1.953644	0.0178724	0.0120179
R-HSA-418359	Reduction of cytosolic Ca++ levels	14	1.953115	0.0214105	0.0143970
R-HSA-5362768	Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD	54	1.950114	0.0178724	0.0120179
R-HSA-373760	L1CAM interactions	111	1.946890	0.0178724	0.0120179
R-HSA-4641258	Degradation of DVL	55	1.945154	0.0178724	0.0120179
R-HSA-174178	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	67	1.944404	0.0207406	0.0139466
R-HSA-425561	Sodium/Calcium exchangers	12	1.942157	0.0218783	0.0147115
R-HSA-451326	Activation of kainate receptors upon glutamate binding	31	1.938252	0.0178724	0.0120179
R-HSA-75815	Ubiquitin-dependent degradation of Cyclin D	50	1.933145	0.0178724	0.0120179
R-HSA-5658442	Regulation of RAS by GAPs	66	1.931985	0.0207406	0.0139466
R-HSA-5607764	CLEC7A (Dectin-1) signaling	98	1.928237	0.0178724	0.0120179
R-HSA-70326	Glucose metabolism	85	1.927372	0.0178724	0.0120179
R-HSA-69002	DNA Replication Pre-Initiation	82	1.925271	0.0178724	0.0120179
R-HSA-5387390	Hh mutants abrogate ligand secretion	56	1.922631	0.0178724	0.0120179
R-HSA-211733	Regulation of activated PAK-2p34 by proteasome mediated degradation	48	1.919536	0.0178724	0.0120179
R-HSA-69601	Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	50	1.919144	0.0178724	0.0120179
R-HSA-69610	p53-Independent DNA Damage Response	50	1.919144	0.0178724	0.0120179
R-HSA-69613	p53-Independent G1/S DNA damage checkpoint	50	1.919144	0.0178724	0.0120179
R-HSA-349425	Autodegradation of the E3 ubiquitin ligase COP1	50	1.918504	0.0178724	0.0120179
R-HSA-174143	APC/C-mediated degradation of cell cycle proteins	81	1.917352	0.0178724	0.0120179
R-HSA-453276	Regulation of mitotic cell cycle	81	1.917352	0.0178724	0.0120179
R-HSA-936837	Ion transport by P-type ATPases	54	1.915884	0.0178724	0.0120179
R-HSA-164378	PKA activation in glucagon signalling	16	1.914764	0.0214105	0.0143970
R-HSA-71406	Pyruvate metabolism and Citric Acid (TCA) cycle	52	1.913308	0.0207406	0.0139466
R-HSA-163685	Integration of energy metabolism	101	1.908613	0.0178724	0.0120179
R-HSA-176409	APC/C:Cdc20 mediated degradation of mitotic proteins	72	1.905243	0.0178724	0.0120179
R-HSA-176814	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	72	1.905243	0.0178724	0.0120179
R-HSA-195253	Degradation of beta-catenin by the destruction complex	80	1.900618	0.0178724	0.0120179
R-HSA-181429	Serotonin Neurotransmitter Release Cycle	17	1.900033	0.0178724	0.0120179
R-HSA-381676	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	39	1.899815	0.0178724	0.0120179
R-HSA-983168	Antigen processing: Ubiquitination & Proteasome degradation	296	1.891104	0.0178724	0.0120179
R-HSA-5628897	TP53 Regulates Metabolic Genes	84	1.882978	0.0178724	0.0120179
R-HSA-1169091	Activation of NF-kappaB in B cells	65	1.869737	0.0207406	0.0139466
R-HSA-70263	Gluconeogenesis	29	1.869377	0.0178724	0.0120179
R-HSA-977443	GABA receptor activation	51	1.867643	0.0207406	0.0139466
R-HSA-983712	Ion channel transport	168	1.866359	0.0178724	0.0120179
R-HSA-5673001	RAF/MAP kinase cascade	224	1.863324	0.0178724	0.0120179
R-HSA-5218921	VEGFR2 mediated cell proliferation	21	1.863316	0.0178724	0.0120179
R-HSA-264642	Acetylcholine Neurotransmitter Release Cycle	14	1.861766	0.0214105	0.0143970
R-HSA-917977	Transferrin endocytosis and recycling	29	1.860765	0.0214105	0.0143970
R-HSA-77387	Insulin receptor recycling	23	1.856669	0.0214105	0.0143970
R-HSA-6811436	COPI-independent Golgi-to-ER retrograde traffic	45	1.854048	0.0178724	0.0120179
R-HSA-432040	Vasopressin regulates renal water homeostasis via Aquaporins	38	1.848467	0.0178724	0.0120179
R-HSA-397014	Muscle contraction	187	1.846668	0.0178724	0.0120179
R-HSA-418346	Platelet homeostasis	85	1.840075	0.0178724	0.0120179
R-HSA-5621481	C-type lectin receptors (CLRs)	123	1.836159	0.0178724	0.0120179
R-HSA-3858494	Beta-catenin independent WNT signaling	139	1.832935	0.0178724	0.0120179
R-HSA-8948751	Regulation of PTEN stability and activity	67	1.832842	0.0207406	0.0139466
R-HSA-1592230	Mitochondrial biogenesis	94	1.832590	0.0178724	0.0120179
R-HSA-69541	Stabilization of p53	55	1.823896	0.0207482	0.0139516
R-HSA-187577	SCF(Skp2)-mediated degradation of p27/p21	60	1.821204	0.0207406	0.0139466
R-HSA-1855183	Synthesis of IP2, IP, and Ins in the cytosol	13	1.818648	0.0215245	0.0144737
R-HSA-5099900	WNT5A-dependent internalization of FZD4	15	1.814820	0.0214105	0.0143970
R-HSA-388844	Receptor-type tyrosine-protein phosphatases	20	1.810257	0.0178724	0.0120179
R-HSA-112308	Presynaptic depolarization and calcium channel opening	13	1.809298	0.0215245	0.0144737
R-HSA-5684996	MAPK1/MAPK3 signaling	230	1.808475	0.0178724	0.0120179
R-HSA-418360	Platelet calcium homeostasis	29	1.802779	0.0214105	0.0143970
R-HSA-74752	Signaling by Insulin receptor	66	1.799373	0.0207406	0.0139466
R-HSA-69306	DNA Replication	123	1.795906	0.0178724	0.0120179
R-HSA-69563	p53-Dependent G1 DNA Damage Response	64	1.788087	0.0207406	0.0139466
R-HSA-69580	p53-Dependent G1/S DNA damage checkpoint	64	1.788087	0.0207406	0.0139466
R-HSA-450408	AUF1 (hnRNP D0) binds and destabilizes mRNA	54	1.785273	0.0207406	0.0139466
R-HSA-1483255	PI Metabolism	82	1.783341	0.0178724	0.0120179
R-HSA-69481	G2/M Checkpoints	162	1.779985	0.0178724	0.0120179
R-HSA-70221	Glycogen breakdown (glycogenolysis)	17	1.779805	0.0357691	0.0240521
R-HSA-8949664	Processing of SMDT1	16	1.775758	0.0426610	0.0286864
R-HSA-2871837	FCERI mediated NF-kB activation	78	1.772306	0.0178724	0.0120179
R-HSA-5358346	Hedgehog ligand biogenesis	62	1.768960	0.0207406	0.0139466
R-HSA-8951664	Neddylation	225	1.768298	0.0178724	0.0120179
R-HSA-69239	Synthesis of DNA	116	1.767844	0.0178724	0.0120179
R-HSA-445717	Aquaporin-mediated transport	44	1.767032	0.0178724	0.0120179
R-HSA-1222556	ROS and RNS production in phagocytes	34	1.764762	0.0208719	0.0140349
R-HSA-69615	G1/S DNA Damage Checkpoints	66	1.763056	0.0207406	0.0139466
R-HSA-114508	Effects of PIP2 hydrolysis	26	1.763054	0.0214105	0.0143970
R-HSA-5210891	Uptake and function of anthrax toxins	13	1.757143	0.0436155	0.0293283
R-HSA-1632852	Macroautophagy	91	1.751486	0.0207406	0.0139466
R-HSA-70171	Glycolysis	68	1.746961	0.0207406	0.0139466
R-HSA-163359	Glucagon signaling in metabolic regulation	30	1.742006	0.0212825	0.0143109
R-HSA-4641257	Degradation of AXIN	53	1.740082	0.0207406	0.0139466
R-HSA-5683057	MAPK family signaling cascades	266	1.739771	0.0178724	0.0120179
R-HSA-8856688	Golgi-to-ER retrograde transport	124	1.738128	0.0205499	0.0138183
R-HSA-8949215	Mitochondrial calcium ion transport	23	1.736394	0.0287430	0.0193276
R-HSA-5358351	Signaling by Hedgehog	143	1.735278	0.0178724	0.0120179
R-HSA-4608870	Asymmetric localization of PCP proteins	62	1.734835	0.0207406	0.0139466
R-HSA-4086400	PCP/CE pathway	89	1.733743	0.0178724	0.0120179
R-HSA-8856828	Clathrin-mediated endocytosis	137	1.732979	0.0178724	0.0120179
R-HSA-1852241	Organelle biogenesis and maintenance	286	1.732181	0.0178724	0.0120179
R-HSA-453274	Mitotic G2-G2/M phases	187	1.727232	0.0178724	0.0120179
R-HSA-1483249	Inositol phosphate metabolism	48	1.725305	0.0207916	0.0139809
R-HSA-162909	Host Interactions of HIV factors	125	1.720101	0.0205499	0.0138183
R-HSA-69275	G2/M Transition	185	1.715159	0.0178724	0.0120179
R-HSA-8941858	Regulation of RUNX3 expression and activity	55	1.706189	0.0338234	0.0227438
R-HSA-2132295	MHC class II antigen presentation	110	1.704641	0.0178724	0.0120179
R-HSA-8856825	Cargo recognition for clathrin-mediated endocytosis	97	1.697754	0.0321613	0.0216261
R-HSA-166520	Signaling by NTRKs	97	1.685550	0.0321613	0.0216261
R-HSA-69620	Cell Cycle Checkpoints	279	1.685291	0.0178724	0.0120179
R-HSA-382556	ABC-family proteins mediated transport	100	1.684830	0.0257145	0.0172911
R-HSA-1855204	Synthesis of IP3 and IP4 in the cytosol	27	1.677675	0.0357691	0.0240521
R-HSA-381753	Olfactory Signaling Pathway	49	1.668289	0.0338234	0.0227438
R-HSA-2871809	FCERI mediated Ca+2 mobilization	31	1.663831	0.0344930	0.0231940
R-HSA-379724	tRNA Aminoacylation	42	1.646165	0.0404812	0.0272207
R-HSA-5205647	Mitophagy	29	1.640185	0.0421256	0.0283264
R-HSA-8852276	The role of GTSE1 in G2/M progression after G2 checkpoint	69	1.639983	0.0329968	0.0221879
R-HSA-2682334	EPH-Ephrin signaling	92	1.638920	0.0492122	0.0330917
R-HSA-5687128	MAPK6/MAPK4 signaling	84	1.634592	0.0497877	0.0334786
R-HSA-5619084	ABC transporter disorders	75	1.617943	0.0385323	0.0259102
R-HSA-380270	Recruitment of mitotic centrosome proteins and complexes	79	1.584249	0.0385323	0.0259102
R-HSA-380287	Centrosome maturation	79	1.584249	0.0385323	0.0259102
R-HSA-9006925	Intracellular signaling by second messengers	285	1.581834	0.0201686	0.0135619
R-HSA-187037	Signaling by NTRK1 (TRKA)	77	1.568724	0.0497877	0.0334786
R-HSA-2467813	Separation of Sister Chromatids	175	1.560684	0.0239269	0.0160891
R-HSA-162906	HIV Infection	224	1.540690	0.0201734	0.0135652
R-HSA-983169	Class I MHC mediated antigen processing & presentation	355	1.536145	0.0196709	0.0132272
R-HSA-9007101	Rab regulation of trafficking	122	1.535149	0.0369855	0.0248701
R-HSA-69206	G1/S Transition	131	1.520515	0.0368454	0.0247758
R-HSA-68882	Mitotic Anaphase	186	1.488832	0.0457744	0.0307800
R-HSA-2555396	Mitotic Metaphase and Anaphase	187	1.486601	0.0404812	0.0272207
R-HSA-69242	S Phase	158	1.483756	0.0404812	0.0272207
R-HSA-9609507	Protein localization	158	1.479809	0.0404812	0.0272207
R-HSA-5617833	Cilium Assembly	192	1.474133	0.0456150	0.0306728
R-HSA-6811442	Intra-Golgi and retrograde Golgi-to-ER traffic	191	1.414316	0.0497877	0.0334786
R-HSA-195721	Signaling by WNT	309	1.387903	0.0279923	0.0188228
R-HSA-5663205	Infectious disease	368	1.375228	0.0274275	0.0184430
R-HSA-8953897	Cellular responses to external stimuli	498	1.347697	0.0404812	0.0272207

Enriched terms for module #73B000 (MTcor = 0.94)

ID	Description	setSize	NES	p.adjust	qvalues
R-HSA-5625886	Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	59	3.468265	0.0117461	0.0078154
R-HSA-5334118	DNA methylation	57	3.422280	0.0117461	0.0078154
R-HSA-2299718	Condensation of Prophase Chromosomes	66	3.384387	0.0117461	0.0078154
R-HSA-73728	RNA Polymerase I Promoter Opening	57	3.382260	0.0117461	0.0078154
R-HSA-427359	SIRT1 negatively regulates rRNA expression	62	3.273416	0.0117461	0.0078154
R-HSA-212300	PRC2 methylates histones and DNA	67	3.260046	0.0117461	0.0078154
R-HSA-912446	Meiotic recombination	77	3.229282	0.0117461	0.0078154
R-HSA-427389	ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	70	3.211547	0.0117461	0.0078154
R-HSA-1912408	Pre-NOTCH Transcription and Translation	87	3.192557	0.0117461	0.0078154
R-HSA-1912422	Pre-NOTCH Expression and Processing	103	3.141059	0.0117461	0.0078154
R-HSA-8936459	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	87	3.121136	0.0117461	0.0078154
R-HSA-171306	Packaging Of Telomere Ends	45	3.107865	0.0117461	0.0078154
R-HSA-5625740	RHO GTPases activate PKNs	87	3.101239	0.0117461	0.0078154
R-HSA-201722	Formation of the beta-catenin:TCF transactivating complex	83	3.089756	0.0117461	0.0078154
R-HSA-110330	Recognition and association of DNA glycosylase with site containing an affected purine	49	3.083089	0.0117461	0.0078154
R-HSA-110331	Cleavage of the damaged purine	49	3.083089	0.0117461	0.0078154
R-HSA-73927	Depurination	49	3.083089	0.0117461	0.0078154
R-HSA-1500620	Meiosis	106	3.075246	0.0117461	0.0078154
R-HSA-977225	Amyloid fiber formation	92	3.070625	0.0117461	0.0078154
R-HSA-1474165	Reproduction	121	3.065717	0.0117461	0.0078154
R-HSA-3214815	HDACs deacetylate histones	89	3.053304	0.0117461	0.0078154
R-HSA-2559582	Senescence-Associated Secretory Phenotype (SASP)	103	3.053189	0.0117461	0.0078154
R-HSA-5617472	Activation of anterior HOX genes in hindbrain development during early embryogenesis	105	3.023189	0.0117461	0.0078154
R-HSA-5619507	Activation of HOX genes during differentiation	105	3.023189	0.0117461	0.0078154
R-HSA-3214842	HDMs demethylate histones	50	3.021979	0.0117461	0.0078154
R-HSA-9018519	Estrogen-dependent gene expression	139	3.014750	0.0117461	0.0078154
R-HSA-1221632	Meiotic synapsis	69	3.002054	0.0117461	0.0078154
R-HSA-73772	RNA Polymerase I Promoter Escape	85	2.999443	0.0117461	0.0078154
R-HSA-5250924	B-WICH complex positively regulates rRNA expression	85	2.972633	0.0117461	0.0078154
R-HSA-110328	Recognition and association of DNA glycosylase with site containing an affected pyrimidine	54	2.961401	0.0117461	0.0078154
R-HSA-110329	Cleavage of the damaged pyrimidine	54	2.961401	0.0117461	0.0078154
R-HSA-73928	Depyrimidination	54	2.961401	0.0117461	0.0078154
R-HSA-73929	Base-Excision Repair, AP Site Formation	56	2.959082	0.0117461	0.0078154
R-HSA-5578749	Transcriptional regulation by small RNAs	100	2.953369	0.0117461	0.0078154
R-HSA-606279	Deposition of new CENPA-containing nucleosomes at the centromere	67	2.926504	0.0117461	0.0078154
R-HSA-774815	Nucleosome assembly	67	2.926504	0.0117461	0.0078154
R-HSA-3214858	RMTs methylate histone arginines	74	2.896146	0.0117461	0.0078154
R-HSA-427413	NoRC negatively regulates rRNA expression	100	2.842392	0.0117461	0.0078154
R-HSA-68875	Mitotic Prophase	134	2.834253	0.0117461	0.0078154
R-HSA-2559586	DNA Damage/Telomere Stress Induced Senescence	72	2.823211	0.0117461	0.0078154
R-HSA-5250913	Positive epigenetic regulation of rRNA expression	100	2.816024	0.0117461	0.0078154
R-HSA-5250941	Negative epigenetic regulation of rRNA expression	103	2.786659	0.0117461	0.0078154
R-HSA-73864	RNA Polymerase I Transcription	105	2.775882	0.0117461	0.0078154
R-HSA-73854	RNA Polymerase I Promoter Clearance	104	2.753578	0.0117461	0.0078154
R-HSA-3214841	PKMTs methylate histone lysines	68	2.736044	0.0117461	0.0078154
R-HSA-2559580	Oxidative Stress Induced Senescence	116	2.726098	0.0117461	0.0078154
R-HSA-157579	Telomere Maintenance	74	2.707148	0.0117461	0.0078154
R-HSA-211000	Gene Silencing by RNA	128	2.642296	0.0117461	0.0078154
R-HSA-3214847	HATs acetylate histones	134	2.626393	0.0117461	0.0078154
R-HSA-8939211	ESR-mediated signaling	205	2.605186	0.0117461	0.0078154
R-HSA-73884	Base Excision Repair	84	2.554506	0.0117461	0.0078154
R-HSA-8939236	RUNX1 regulates transcription of genes involved in differentiation of HSCs	120	2.552006	0.0117461	0.0078154
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling	88	2.512160	0.0117461	0.0078154
R-HSA-73886	Chromosome Maintenance	101	2.511605	0.0117461	0.0078154
R-HSA-2559583	Cellular Senescence	183	2.502976	0.0117461	0.0078154
R-HSA-6783783	Interleukin-10 signaling	34	2.488127	0.0117461	0.0078154
R-HSA-5693571	Nonhomologous End-Joining (NHEJ)	66	2.488032	0.0117461	0.0078154
R-HSA-212165	Epigenetic regulation of gene expression	140	2.483332	0.0117461	0.0078154
R-HSA-5693606	DNA Double Strand Break Response	74	2.426852	0.0117461	0.0078154
R-HSA-5693565	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	73	2.423707	0.0117461	0.0078154
R-HSA-8941326	RUNX2 regulates bone development	30	2.403258	0.0117461	0.0078154
R-HSA-1566948	Elastic fibre formation	43	2.391125	0.0117461	0.0078154
R-HSA-9006931	Signaling by Nuclear Receptors	244	2.384423	0.0117461	0.0078154
R-HSA-5693607	Processing of DNA double-strand break ends	94	2.371347	0.0117461	0.0078154
R-HSA-1266695	Interleukin-7 signaling	33	2.369369	0.0117461	0.0078154
R-HSA-69473	G2/M DNA damage checkpoint	91	2.348016	0.0117461	0.0078154
R-HSA-1474244	Extracellular matrix organization	263	2.321442	0.0117461	0.0078154
R-HSA-5693567	HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	126	2.273638	0.0117461	0.0078154
R-HSA-3247509	Chromatin modifying enzymes	259	2.273256	0.0117461	0.0078154
R-HSA-4839726	Chromatin organization	259	2.273256	0.0117461	0.0078154
R-HSA-157118	Signaling by NOTCH	224	2.221206	0.0117461	0.0078154
R-HSA-3000170	Syndecan interactions	27	2.212491	0.0117461	0.0078154
R-HSA-2129379	Molecules associated with elastic fibres	36	2.209138	0.0117461	0.0078154
R-HSA-8940973	RUNX2 regulates osteoblast differentiation	23	2.208080	0.0117461	0.0078154
R-HSA-8878171	Transcriptional regulation by RUNX1	218	2.204695	0.0117461	0.0078154
R-HSA-5693538	Homology Directed Repair	132	2.198307	0.0117461	0.0078154
R-HSA-8875878	MET promotes cell motility	40	2.179348	0.0117461	0.0078154
R-HSA-75205	Dissolution of Fibrin Clot	10	2.112298	0.0117461	0.0078154
R-HSA-3108232	SUMO E3 ligases SUMOylate target proteins	175	2.104719	0.0117461	0.0078154
R-HSA-2022090	Assembly of collagen fibrils and other multimeric structures	56	2.096615	0.0117461	0.0078154
R-HSA-1474290	Collagen formation	84	2.092427	0.0117461	0.0078154
R-HSA-3000171	Non-integrin membrane-ECM interactions	59	2.091970	0.0117461	0.0078154
R-HSA-2197563	NOTCH2 intracellular domain regulates transcription	10	2.071611	0.0117461	0.0078154
R-HSA-8874081	MET activates PTK2 signaling	30	2.049986	0.0117461	0.0078154
R-HSA-8941856	RUNX3 regulates NOTCH signaling	14	2.049880	0.0117461	0.0078154
R-HSA-201681	TCF dependent signaling in response to WNT	215	2.041925	0.0117461	0.0078154
R-HSA-209560	NF-kB is activated and signals survival	13	2.031102	0.0202929	0.0135020
R-HSA-2173796	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	31	2.022195	0.0117461	0.0078154
R-HSA-2990846	SUMOylation	181	2.022195	0.0117461	0.0078154
R-HSA-6783589	Interleukin-6 family signaling	23	2.018325	0.0117461	0.0078154
R-HSA-3000480	Scavenging by Class A Receptors	18	2.014909	0.0197925	0.0131691
R-HSA-4551638	SUMOylation of chromatin organization proteins	70	2.014336	0.0117461	0.0078154
R-HSA-1980145	Signaling by NOTCH2	31	2.001981	0.0117461	0.0078154
R-HSA-211976	Endogenous sterols	20	1.996679	0.0198251	0.0131908
R-HSA-2173782	Binding and Uptake of Ligands by Scavenger Receptors	36	1.996595	0.0117461	0.0078154
R-HSA-216083	Integrin cell surface interactions	75	1.992018	0.0117461	0.0078154
R-HSA-9012852	Signaling by NOTCH3	47	1.991023	0.0117461	0.0078154
R-HSA-2173793	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	43	1.984741	0.0117461	0.0078154
R-HSA-2243919	Crosslinking of collagen fibrils	18	1.979909	0.0197925	0.0131691
R-HSA-2028269	Signaling by Hippo	20	1.974711	0.0198251	0.0131908
R-HSA-140342	Apoptosis induced DNA fragmentation	13	1.952558	0.0344850	0.0229448
R-HSA-5693532	DNA Double-Strand Break Repair	160	1.929721	0.0117461	0.0078154
R-HSA-210744	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	13	1.927565	0.0344850	0.0229448
R-HSA-3000178	ECM proteoglycans	70	1.926631	0.0117461	0.0078154
R-HSA-9617828	FOXO-mediated transcription of cell cycle genes	17	1.923799	0.0202929	0.0135020
R-HSA-3000157	Laminin interactions	30	1.914379	0.0117461	0.0078154
R-HSA-193639	p75NTR signals via NF-kB	16	1.911000	0.0117461	0.0078154
R-HSA-9013508	NOTCH3 Intracellular Domain Regulates Transcription	23	1.904380	0.0117461	0.0078154
R-HSA-5260271	Diseases of Immune System	24	1.879596	0.0278870	0.0185548
R-HSA-5602358	Diseases associated with the TLR signaling cascade	24	1.879596	0.0278870	0.0185548
R-HSA-446353	Cell-extracellular matrix interactions	18	1.879476	0.0197925	0.0131691
R-HSA-9013695	NOTCH4 Intracellular Domain Regulates Transcription	20	1.873682	0.0276905	0.0184241
R-HSA-2032785	YAP1- and WWTR1 (TAZ)-stimulated gene expression	12	1.873360	0.0344850	0.0229448
R-HSA-6803211	TP53 Regulates Transcription of Death Receptors and Ligands	12	1.868562	0.0344850	0.0229448
R-HSA-111461	Cytochrome c-mediated apoptotic response	13	1.868298	0.0407191	0.0270927
R-HSA-5213460	RIPK1-mediated regulated necrosis	19	1.867988	0.0197925	0.0131691
R-HSA-5218859	Regulated Necrosis	19	1.867988	0.0197925	0.0131691
R-HSA-2022870	Chondroitin sulfate biosynthesis	19	1.867393	0.0197925	0.0131691
R-HSA-1650814	Collagen biosynthesis and modifying enzymes	65	1.837174	0.0117461	0.0078154
R-HSA-1474228	Degradation of the extracellular matrix	117	1.836332	0.0117461	0.0078154
R-HSA-195258	RHO GTPase Effectors	304	1.835419	0.0117461	0.0078154
R-HSA-193692	Regulated proteolysis of p75NTR	11	1.831270	0.0283083	0.0188351
R-HSA-449147	Signaling by Interleukins	393	1.805247	0.0117461	0.0078154
R-HSA-198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	95	1.803718	0.0117461	0.0078154
R-HSA-1236977	Endosomal/Vacuolar pathway	11	1.798824	0.0414761	0.0275964
R-HSA-6788467	IL-6-type cytokine receptor ligand interactions	16	1.787366	0.0344850	0.0229448
R-HSA-2173795	Downregulation of SMAD2/3:SMAD4 transcriptional activity	23	1.784984	0.0409849	0.0272696
R-HSA-174490	Membrane binding and targetting of GAG proteins	14	1.783827	0.0479042	0.0318734
R-HSA-174495	Synthesis And Processing Of GAG, GAGPOL Polyproteins	14	1.783827	0.0479042	0.0318734
R-HSA-977606	Regulation of Complement cascade	32	1.781757	0.0197925	0.0131691
R-HSA-5689901	Metalloprotease DUBs	33	1.781302	0.0273723	0.0182123
R-HSA-380108	Chemokine receptors bind chemokines	24	1.775479	0.0406867	0.0270712
R-HSA-166658	Complement cascade	38	1.770962	0.0274778	0.0182825
R-HSA-1059683	Interleukin-6 signaling	11	1.770686	0.0414761	0.0275964
R-HSA-4755510	SUMOylation of immune response proteins	11	1.770228	0.0414761	0.0275964
R-HSA-8957275	Post-translational protein phosphorylation	93	1.762486	0.0117461	0.0078154
R-HSA-8866654	E3 ubiquitin ligases ubiquitinate target proteins	58	1.760725	0.0117461	0.0078154
R-HSA-202733	Cell surface interactions at the vascular wall	110	1.752706	0.0117461	0.0078154
R-HSA-909733	Interferon alpha/beta signaling	56	1.717716	0.0278020	0.0184983
R-HSA-5656169	Termination of translesion DNA synthesis	32	1.710565	0.0388947	0.0258789
R-HSA-381426	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	102	1.696654	0.0117461	0.0078154
R-HSA-195721	Signaling by WNT	309	1.684956	0.0117461	0.0078154
R-HSA-1442490	Collagen degradation	51	1.680047	0.0278696	0.0185433
R-HSA-3560782	Diseases associated with glycosaminoglycan metabolism	40	1.673642	0.0278085	0.0185026
R-HSA-3906995	Diseases associated with O-glycosylation of proteins	55	1.659918	0.0344850	0.0229448
R-HSA-8852135	Protein ubiquitination	77	1.644277	0.0283083	0.0188351
R-HSA-68886	M Phase	370	1.643709	0.0117461	0.0078154
R-HSA-446728	Cell junction organization	78	1.639326	0.0344850	0.0229448
R-HSA-3781865	Diseases of glycosylation	128	1.636125	0.0117461	0.0078154
R-HSA-168643	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	55	1.631757	0.0344850	0.0229448
R-HSA-2262752	Cellular responses to stress	405	1.625530	0.0117461	0.0078154
R-HSA-1793185	Chondroitin sulfate/dermatan sulfate metabolism	49	1.625400	0.0278969	0.0185614
R-HSA-381340	Transcriptional regulation of white adipocyte differentiation	78	1.618267	0.0344850	0.0229448
R-HSA-9006936	Signaling by TGF-beta family members	97	1.598987	0.0404981	0.0269457
R-HSA-6806834	Signaling by MET	78	1.591541	0.0344850	0.0229448
R-HSA-194315	Signaling by Rho GTPases	427	1.585235	0.0117461	0.0078154
R-HSA-73894	DNA Repair	322	1.439976	0.0117461	0.0078154
R-HSA-6798695	Neutrophil degranulation	426	1.411085	0.0117461	0.0078154
R-HSA-8953897	Cellular responses to external stimuli	498	1.368646	0.0117461	0.0078154

Enriched terms for module #EE8045 (MTcor = 0.93)

ID	Description	setSize	NES	p.adjust	qvalues
R-HSA-5625886	Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	59	3.423865	0.0147558	0.0095281
R-HSA-5334118	DNA methylation	57	3.408554	0.0147558	0.0095281
R-HSA-73728	RNA Polymerase I Promoter Opening	57	3.357615	0.0147558	0.0095281
R-HSA-2299718	Condensation of Prophase Chromosomes	66	3.273274	0.0147558	0.0095281
R-HSA-427359	SIRT1 negatively regulates rRNA expression	62	3.258986	0.0147558	0.0095281
R-HSA-212300	PRC2 methylates histones and DNA	67	3.187458	0.0147558	0.0095281
R-HSA-3214815	HDACs deacetylate histones	89	3.173601	0.0147558	0.0095281
R-HSA-1912408	Pre-NOTCH Transcription and Translation	87	3.151928	0.0147558	0.0095281
R-HSA-912446	Meiotic recombination	77	3.147819	0.0147558	0.0095281
R-HSA-427389	ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	70	3.136607	0.0147558	0.0095281
R-HSA-8936459	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	87	3.126798	0.0147558	0.0095281
R-HSA-5625740	RHO GTPases activate PKNs	87	3.077224	0.0147558	0.0095281
R-HSA-171306	Packaging Of Telomere Ends	45	3.026010	0.0147558	0.0095281
R-HSA-1500620	Meiosis	106	3.019959	0.0147558	0.0095281
R-HSA-73772	RNA Polymerase I Promoter Escape	85	3.010768	0.0147558	0.0095281
R-HSA-1221632	Meiotic synapsis	69	3.001838	0.0147558	0.0095281
R-HSA-1912422	Pre-NOTCH Expression and Processing	103	2.983569	0.0147558	0.0095281
R-HSA-1474165	Reproduction	121	2.976872	0.0147558	0.0095281
R-HSA-977225	Amyloid fiber formation	92	2.976040	0.0147558	0.0095281
R-HSA-110330	Recognition and association of DNA glycosylase with site containing an affected purine	49	2.945466	0.0147558	0.0095281
R-HSA-110331	Cleavage of the damaged purine	49	2.945466	0.0147558	0.0095281
R-HSA-73927	Depurination	49	2.945466	0.0147558	0.0095281
R-HSA-5250924	B-WICH complex positively regulates rRNA expression	85	2.932192	0.0147558	0.0095281
R-HSA-201722	Formation of the beta-catenin:TCF transactivating complex	83	2.915745	0.0147558	0.0095281
R-HSA-2559582	Senescence-Associated Secretory Phenotype (SASP)	103	2.908049	0.0147558	0.0095281
R-HSA-110328	Recognition and association of DNA glycosylase with site containing an affected pyrimidine	54	2.866451	0.0147558	0.0095281
R-HSA-110329	Cleavage of the damaged pyrimidine	54	2.866451	0.0147558	0.0095281
R-HSA-73928	Depyrimidination	54	2.866451	0.0147558	0.0095281
R-HSA-427413	NoRC negatively regulates rRNA expression	100	2.865425	0.0147558	0.0095281
R-HSA-5578749	Transcriptional regulation by small RNAs	100	2.858178	0.0147558	0.0095281
R-HSA-5617472	Activation of anterior HOX genes in hindbrain development during early embryogenesis	105	2.849947	0.0147558	0.0095281
R-HSA-5619507	Activation of HOX genes during differentiation	105	2.849947	0.0147558	0.0095281
R-HSA-73929	Base-Excision Repair, AP Site Formation	56	2.836182	0.0147558	0.0095281
R-HSA-9018519	Estrogen-dependent gene expression	139	2.831378	0.0147558	0.0095281
R-HSA-606279	Deposition of new CENPA-containing nucleosomes at the centromere	67	2.825716	0.0147558	0.0095281
R-HSA-774815	Nucleosome assembly	67	2.825716	0.0147558	0.0095281
R-HSA-2559586	DNA Damage/Telomere Stress Induced Senescence	72	2.813244	0.0147558	0.0095281
R-HSA-5250941	Negative epigenetic regulation of rRNA expression	103	2.802212	0.0147558	0.0095281
R-HSA-3214842	HDMs demethylate histones	50	2.793935	0.0147558	0.0095281
R-HSA-73864	RNA Polymerase I Transcription	105	2.755552	0.0147558	0.0095281
R-HSA-5250913	Positive epigenetic regulation of rRNA expression	100	2.738779	0.0147558	0.0095281
R-HSA-73854	RNA Polymerase I Promoter Clearance	104	2.737481	0.0147558	0.0095281
R-HSA-3214858	RMTs methylate histone arginines	74	2.725178	0.0147558	0.0095281
R-HSA-3214847	HATs acetylate histones	134	2.666186	0.0147558	0.0095281
R-HSA-68875	Mitotic Prophase	134	2.658509	0.0147558	0.0095281
R-HSA-157579	Telomere Maintenance	74	2.658310	0.0147558	0.0095281
R-HSA-5693565	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	73	2.639181	0.0147558	0.0095281
R-HSA-5693606	DNA Double Strand Break Response	74	2.638258	0.0147558	0.0095281
R-HSA-5693571	Nonhomologous End-Joining (NHEJ)	66	2.638140	0.0147558	0.0095281
R-HSA-211000	Gene Silencing by RNA	128	2.611310	0.0147558	0.0095281
R-HSA-3214841	PKMTs methylate histone lysines	68	2.549697	0.0147558	0.0095281
R-HSA-2559580	Oxidative Stress Induced Senescence	116	2.536816	0.0147558	0.0095281
R-HSA-212165	Epigenetic regulation of gene expression	140	2.528168	0.0147558	0.0095281
R-HSA-73886	Chromosome Maintenance	101	2.477316	0.0147558	0.0095281
R-HSA-73884	Base Excision Repair	84	2.462647	0.0147558	0.0095281
R-HSA-8939236	RUNX1 regulates transcription of genes involved in differentiation of HSCs	120	2.451663	0.0147558	0.0095281
R-HSA-8939211	ESR-mediated signaling	205	2.437913	0.0147558	0.0095281
R-HSA-5693607	Processing of DNA double-strand break ends	94	2.393373	0.0147558	0.0095281
R-HSA-69473	G2/M DNA damage checkpoint	91	2.384414	0.0147558	0.0095281
R-HSA-3247509	Chromatin modifying enzymes	259	2.368614	0.0147558	0.0095281
R-HSA-4839726	Chromatin organization	259	2.368614	0.0147558	0.0095281
R-HSA-1474290	Collagen formation	84	2.319970	0.0147558	0.0095281
R-HSA-2559583	Cellular Senescence	183	2.277798	0.0147558	0.0095281
R-HSA-8878171	Transcriptional regulation by RUNX1	218	2.246526	0.0147558	0.0095281
R-HSA-2022090	Assembly of collagen fibrils and other multimeric structures	56	2.246405	0.0147558	0.0095281
R-HSA-5693567	HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	126	2.217461	0.0147558	0.0095281
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling	88	2.213152	0.0147558	0.0095281
R-HSA-1474244	Extracellular matrix organization	263	2.201084	0.0147558	0.0095281
R-HSA-9006931	Signaling by Nuclear Receptors	244	2.195094	0.0147558	0.0095281
R-HSA-1650814	Collagen biosynthesis and modifying enzymes	65	2.193222	0.0147558	0.0095281
R-HSA-6783783	Interleukin-10 signaling	34	2.173643	0.0147558	0.0095281
R-HSA-5260271	Diseases of Immune System	24	2.124050	0.0147558	0.0095281
R-HSA-5602358	Diseases associated with the TLR signaling cascade	24	2.124050	0.0147558	0.0095281
R-HSA-5693538	Homology Directed Repair	132	2.122800	0.0147558	0.0095281
R-HSA-5689901	Metalloprotease DUBs	33	2.118768	0.0147558	0.0095281
R-HSA-216083	Integrin cell surface interactions	75	2.070907	0.0147558	0.0095281
R-HSA-3108232	SUMO E3 ligases SUMOylate target proteins	175	2.062557	0.0147558	0.0095281
R-HSA-8875878	MET promotes cell motility	40	2.034390	0.0147558	0.0095281
R-HSA-4551638	SUMOylation of chromatin organization proteins	70	2.026914	0.0147558	0.0095281
R-HSA-977606	Regulation of Complement cascade	32	2.026791	0.0147558	0.0095281
R-HSA-1266695	Interleukin-7 signaling	33	2.021810	0.0147558	0.0095281
R-HSA-166658	Complement cascade	38	2.012917	0.0147558	0.0095281
R-HSA-1566948	Elastic fibre formation	43	2.010537	0.0147558	0.0095281
R-HSA-1442490	Collagen degradation	51	2.009278	0.0147558	0.0095281
R-HSA-5693532	DNA Double-Strand Break Repair	160	1.999490	0.0147558	0.0095281
R-HSA-2028269	Signaling by Hippo	20	1.977259	0.0147558	0.0095281
R-HSA-2990846	SUMOylation	181	1.958994	0.0147558	0.0095281
R-HSA-68884	Mitotic Telophase/Cytokinesis	12	1.944953	0.0147558	0.0095281
R-HSA-157118	Signaling by NOTCH	224	1.939001	0.0147558	0.0095281
R-HSA-4755510	SUMOylation of immune response proteins	11	1.938659	0.0147558	0.0095281
R-HSA-198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	95	1.934964	0.0147558	0.0095281
R-HSA-8941856	RUNX3 regulates NOTCH signaling	14	1.925882	0.0147558	0.0095281
R-HSA-351906	Apoptotic cleavage of cell adhesion proteins	11	1.922341	0.0147558	0.0095281
R-HSA-2470946	Cohesin Loading onto Chromatin	10	1.917789	0.0147558	0.0095281
R-HSA-5213460	RIPK1-mediated regulated necrosis	19	1.914879	0.0147558	0.0095281
R-HSA-5218859	Regulated Necrosis	19	1.914879	0.0147558	0.0095281
R-HSA-983695	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	29	1.913908	0.0151148	0.0097599
R-HSA-8874081	MET activates PTK2 signaling	30	1.912836	0.0147558	0.0095281
R-HSA-2173793	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	43	1.910455	0.0147558	0.0095281
R-HSA-166663	Initial triggering of complement	18	1.897928	0.0147558	0.0095281
R-HSA-8940973	RUNX2 regulates osteoblast differentiation	23	1.894360	0.0147558	0.0095281
R-HSA-2197563	NOTCH2 intracellular domain regulates transcription	10	1.892793	0.0147558	0.0095281
R-HSA-210744	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	13	1.891067	0.0154234	0.0099592
R-HSA-2468052	Establishment of Sister Chromatid Cohesion	11	1.890788	0.0220671	0.0142491
R-HSA-1474228	Degradation of the extracellular matrix	117	1.886363	0.0147558	0.0095281
R-HSA-3000178	ECM proteoglycans	70	1.877492	0.0147558	0.0095281
R-HSA-156902	Peptide chain elongation	85	1.875282	0.0147558	0.0095281
R-HSA-2129379	Molecules associated with elastic fibres	36	1.869785	0.0147558	0.0095281
R-HSA-877300	Interferon gamma signaling	83	1.869736	0.0147558	0.0095281
R-HSA-844456	The NLRP3 inflammasome	15	1.869192	0.0147558	0.0095281
R-HSA-140534	Caspase activation via Death Receptors in the presence of ligand	16	1.862439	0.0153052	0.0098828
R-HSA-168928	DDX58/IFIH1-mediated induction of interferon-alpha/beta	63	1.861543	0.0147558	0.0095281
R-HSA-2173796	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	31	1.851776	0.0148705	0.0096022
R-HSA-380108	Chemokine receptors bind chemokines	24	1.843850	0.0147558	0.0095281
R-HSA-168643	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	55	1.841317	0.0147558	0.0095281
R-HSA-2871809	FCERI mediated Ca+2 mobilization	31	1.836736	0.0148705	0.0096022
R-HSA-3000171	Non-integrin membrane-ECM interactions	59	1.836485	0.0147558	0.0095281
R-HSA-195258	RHO GTPase Effectors	304	1.820929	0.0147558	0.0095281
R-HSA-194315	Signaling by Rho GTPases	427	1.816330	0.0147558	0.0095281
R-HSA-975956	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	91	1.815893	0.0147558	0.0095281
R-HSA-209560	NF-kB is activated and signals survival	13	1.808667	0.0280512	0.0181132
R-HSA-933542	TRAF6 mediated NF-kB activation	22	1.805904	0.0211187	0.0136367
R-HSA-156842	Eukaryotic Translation Elongation	88	1.803296	0.0147558	0.0095281
R-HSA-2029481	FCGR activation	11	1.798845	0.0336173	0.0217073
R-HSA-8948216	Collagen chain trimerization	42	1.797346	0.0147558	0.0095281
R-HSA-2173795	Downregulation of SMAD2/3:SMAD4 transcriptional activity	23	1.796343	0.0150909	0.0097445
R-HSA-2173782	Binding and Uptake of Ligands by Scavenger Receptors	36	1.795118	0.0147558	0.0095281
R-HSA-372708	p130Cas linkage to MAPK signaling for integrins	12	1.792613	0.0279866	0.0180715
R-HSA-933543	NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	12	1.791496	0.0279866	0.0180715
R-HSA-5675482	Regulation of necroptotic cell death	17	1.791205	0.0153082	0.0098848
R-HSA-2243919	Crosslinking of collagen fibrils	18	1.784329	0.0333499	0.0215347
R-HSA-2032785	YAP1- and WWTR1 (TAZ)-stimulated gene expression	12	1.783150	0.0334883	0.0216240
R-HSA-111465	Apoptotic cleavage of cellular proteins	38	1.782761	0.0147558	0.0095281
R-HSA-76009	Platelet Aggregation (Plug Formation)	33	1.776749	0.0147558	0.0095281
R-HSA-72689	Formation of a pool of free 40S subunits	97	1.773328	0.0147558	0.0095281
R-HSA-3000480	Scavenging by Class A Receptors	18	1.770127	0.0333499	0.0215347
R-HSA-192823	Viral mRNA Translation	85	1.768078	0.0147558	0.0095281
R-HSA-193639	p75NTR signals via NF-kB	16	1.763027	0.0216744	0.0139956
R-HSA-202433	Generation of second messenger molecules	26	1.757591	0.0151148	0.0097599
R-HSA-8941326	RUNX2 regulates bone development	30	1.757124	0.0151148	0.0097599
R-HSA-75205	Dissolution of Fibrin Clot	10	1.751658	0.0336173	0.0217073
R-HSA-5676594	TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	14	1.739092	0.0439633	0.0283879
R-HSA-75153	Apoptotic execution phase	52	1.738860	0.0200338	0.0129362
R-HSA-5621480	Dectin-2 family	12	1.738387	0.0433056	0.0279633
R-HSA-1810476	RIP-mediated NFkB activation via ZBP1	17	1.737595	0.0433056	0.0279633
R-HSA-202427	Phosphorylation of CD3 and TCR zeta chains	15	1.733083	0.0383197	0.0247437
R-HSA-622312	Inflammasomes	20	1.732823	0.0277998	0.0179509
R-HSA-5655862	Translesion synthesis by POLK	17	1.732333	0.0433056	0.0279633
R-HSA-6803211	TP53 Regulates Transcription of Death Receptors and Ligands	12	1.729172	0.0433056	0.0279633
R-HSA-1980145	Signaling by NOTCH2	31	1.725154	0.0263370	0.0170063
R-HSA-446353	Cell-extracellular matrix interactions	18	1.725146	0.0384807	0.0248477
R-HSA-6803207	TP53 Regulates Transcription of Caspase Activators and Caspases	12	1.724677	0.0433056	0.0279633
R-HSA-3000157	Laminin interactions	30	1.724279	0.0210780	0.0136105
R-HSA-72764	Eukaryotic Translation Termination	89	1.720346	0.0147558	0.0095281
R-HSA-354194	GRB2:SOS provides linkage to MAPK signaling for Integrins	12	1.703555	0.0480998	0.0310589
R-HSA-9617828	FOXO-mediated transcription of cell cycle genes	17	1.698662	0.0478871	0.0309216
R-HSA-937041	IKK complex recruitment mediated by RIP1	25	1.682508	0.0325298	0.0210051
R-HSA-350054	Notch-HLH transcription pathway	28	1.681517	0.0325298	0.0210051
R-HSA-73887	Death Receptor Signalling	134	1.671640	0.0147558	0.0095281
R-HSA-201681	TCF dependent signaling in response to WNT	215	1.671581	0.0147558	0.0095281
R-HSA-9013508	NOTCH3 Intracellular Domain Regulates Transcription	23	1.671287	0.0460137	0.0297119
R-HSA-909733	Interferon alpha/beta signaling	56	1.659692	0.0147558	0.0095281
R-HSA-5083635	Defective B3GALTL causes Peters-plus syndrome (PpS)	35	1.659660	0.0315379	0.0203646
R-HSA-9013695	NOTCH4 Intracellular Domain Regulates Transcription	20	1.659234	0.0432009	0.0278956
R-HSA-445989	TAK1 activates NFkB by phosphorylation and activation of IKKs complex	31	1.647604	0.0412447	0.0266325
R-HSA-202733	Cell surface interactions at the vascular wall	110	1.642448	0.0147558	0.0095281
R-HSA-449147	Signaling by Interleukins	393	1.642303	0.0147558	0.0095281
R-HSA-168898	Toll-like Receptor Cascades	146	1.640740	0.0147558	0.0095281
R-HSA-114604	GPVI-mediated activation cascade	31	1.639668	0.0498069	0.0321613
R-HSA-5173214	O-glycosylation of TSR domain-containing proteins	36	1.628517	0.0498069	0.0321613
R-HSA-8866654	E3 ubiquitin ligases ubiquitinate target proteins	58	1.628071	0.0354229	0.0228732
R-HSA-5633008	TP53 Regulates Transcription of Cell Death Genes	43	1.617457	0.0406272	0.0262337
R-HSA-9012852	Signaling by NOTCH3	47	1.605728	0.0366911	0.0236921
R-HSA-68886	M Phase	370	1.602841	0.0147558	0.0095281
R-HSA-2408557	Selenocysteine synthesis	89	1.600130	0.0147558	0.0095281
R-HSA-170834	Signaling by TGF-beta Receptor Complex	72	1.598184	0.0360057	0.0232496
R-HSA-166016	Toll Like Receptor 4 (TLR4) Cascade	124	1.596183	0.0147558	0.0095281
R-HSA-156827	L13a-mediated translational silencing of Ceruloplasmin expression	107	1.587028	0.0147558	0.0095281
R-HSA-2122947	NOTCH1 Intracellular Domain Regulates Transcription	47	1.580947	0.0457982	0.0295727
R-HSA-381426	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	102	1.580331	0.0147558	0.0095281
R-HSA-194840	Rho GTPase cycle	133	1.552178	0.0147558	0.0095281
R-HSA-72706	GTP hydrolysis and joining of the 60S ribosomal subunit	108	1.550432	0.0147558	0.0095281
R-HSA-913531	Interferon Signaling	176	1.548906	0.0147558	0.0095281
R-HSA-9006936	Signaling by TGF-beta family members	97	1.537075	0.0147558	0.0095281
R-HSA-927802	Nonsense-Mediated Decay (NMD)	110	1.535218	0.0147558	0.0095281
R-HSA-975957	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	110	1.535218	0.0147558	0.0095281
R-HSA-8957275	Post-translational protein phosphorylation	93	1.508154	0.0250671	0.0161863
R-HSA-72613	Eukaryotic Translation Initiation	115	1.501685	0.0389742	0.0251664
R-HSA-72737	Cap-dependent Translation Initiation	115	1.501685	0.0389742	0.0251664
R-HSA-6806834	Signaling by MET	78	1.500242	0.0498069	0.0321613
R-HSA-193704	p75 NTR receptor-mediated signalling	93	1.477552	0.0350586	0.0226380
R-HSA-73894	DNA Repair	322	1.453064	0.0147558	0.0095281
R-HSA-195721	Signaling by WNT	309	1.448673	0.0147558	0.0095281
R-HSA-2262752	Cellular responses to stress	405	1.436950	0.0147558	0.0095281

Enriched terms for module #84AD00 (MTcor = -0.93)

ID	Description	setSize	NES	p.adjust	qvalues
R-HSA-1428517	The citric acid (TCA) cycle and respiratory electron transport	170	3.041814	0.0163383	0.0108580
R-HSA-611105	Respiratory electron transport	100	3.001511	0.0163383	0.0108580
R-HSA-163200	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	122	2.963208	0.0163383	0.0108580
R-HSA-6799198	Complex I biogenesis	55	2.687405	0.0163383	0.0108580
R-HSA-5576892	Phase 0 - rapid depolarisation	45	2.672837	0.0163383	0.0108580
R-HSA-71406	Pyruvate metabolism and Citric Acid (TCA) cycle	52	2.566007	0.0163383	0.0108580
R-HSA-888590	GABA synthesis, release, reuptake and degradation	19	2.531036	0.0163383	0.0108580
R-HSA-1268020	Mitochondrial protein import	63	2.472878	0.0163383	0.0108580
R-HSA-112316	Neuronal System	379	2.463509	0.0163383	0.0108580
R-HSA-1296072	Voltage gated Potassium channels	40	2.462057	0.0163383	0.0108580
R-HSA-71403	Citric acid cycle (TCA cycle)	22	2.459002	0.0163383	0.0108580
R-HSA-399719	Trafficking of AMPA receptors	30	2.431389	0.0163383	0.0108580
R-HSA-399721	Glutamate binding, activation of AMPA receptors and synaptic plasticity	30	2.431389	0.0163383	0.0108580
R-HSA-112315	Transmission across Chemical Synapses	245	2.428739	0.0163383	0.0108580
R-HSA-180024	DARPP-32 events	25	2.387230	0.0163383	0.0108580
R-HSA-5682910	LGI-ADAM interactions	14	2.375936	0.0163383	0.0108580
R-HSA-442982	Ras activation upon Ca2+ influx through NMDA receptor	21	2.369297	0.0163383	0.0108580
R-HSA-112310	Neurotransmitter release cycle	47	2.337743	0.0163383	0.0108580
R-HSA-5339562	Uptake and actions of bacterial toxins	30	2.313288	0.0163383	0.0108580
R-HSA-442755	Activation of NMDA receptors and postsynaptic events	84	2.289119	0.0163383	0.0108580
R-HSA-5389840	Mitochondrial translation elongation	86	2.273528	0.0163383	0.0108580
R-HSA-445095	Interaction between L1 and Ankyrins	29	2.272928	0.0163383	0.0108580
R-HSA-5368287	Mitochondrial translation	92	2.245909	0.0163383	0.0108580
R-HSA-112314	Neurotransmitter receptors and postsynaptic signal transmission	184	2.245515	0.0163383	0.0108580
R-HSA-111933	Calmodulin induced events	35	2.242523	0.0163383	0.0108580
R-HSA-111997	CaM pathway	35	2.242523	0.0163383	0.0108580
R-HSA-168799	Neurotoxicity of clostridium toxins	10	2.212582	0.0163383	0.0108580
R-HSA-5368286	Mitochondrial translation initiation	86	2.207501	0.0163383	0.0108580
R-HSA-111996	Ca-dependent events	37	2.207053	0.0163383	0.0108580
R-HSA-5419276	Mitochondrial translation termination	86	2.203616	0.0163383	0.0108580
R-HSA-351202	Metabolism of polyamines	83	2.190904	0.0163383	0.0108580
R-HSA-1489509	DAG and IP3 signaling	41	2.189185	0.0163383	0.0108580
R-HSA-111885	Opioid Signalling	86	2.172653	0.0163383	0.0108580
R-HSA-9617324	Negative regulation of NMDA receptor-mediated neuronal transmission	22	2.157266	0.0163383	0.0108580
R-HSA-350562	Regulation of ornithine decarboxylase (ODC)	49	2.153131	0.0163383	0.0108580
R-HSA-438064	Post NMDA receptor activation events	73	2.150059	0.0163383	0.0108580
R-HSA-1296071	Potassium Channels	92	2.126784	0.0163383	0.0108580
R-HSA-379716	Cytosolic tRNA aminoacylation	24	2.120236	0.0163383	0.0108580
R-HSA-1236978	Cross-presentation of soluble exogenous antigens (endosomes)	47	2.084574	0.0163383	0.0108580
R-HSA-111932	CaMK IV-mediated phosphorylation of CREB	12	2.084286	0.0163383	0.0108580
R-HSA-416993	Trafficking of GluR2-containing AMPA receptors	16	2.075714	0.0163383	0.0108580
R-HSA-8949613	Cristae formation	31	2.075215	0.0163383	0.0108580
R-HSA-438066	Unblocking of NMDA receptors, glutamate binding and activation	22	2.046009	0.0245170	0.0162933
R-HSA-9604323	Negative regulation of NOTCH4 signaling	54	2.042919	0.0163383	0.0108580
R-HSA-9620244	Long-term potentiation	24	2.035952	0.0163383	0.0108580
R-HSA-5673000	RAF activation	32	2.019711	0.0163383	0.0108580
R-HSA-9609507	Protein localization	158	2.018606	0.0163383	0.0108580
R-HSA-70221	Glycogen breakdown (glycogenolysis)	17	2.016710	0.0163383	0.0108580
R-HSA-5628897	TP53 Regulates Metabolic Genes	84	2.011609	0.0163383	0.0108580
R-HSA-442729	CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	10	2.011388	0.0163383	0.0108580
R-HSA-4641258	Degradation of DVL	55	2.006998	0.0163383	0.0108580
R-HSA-163615	PKA activation	18	2.002056	0.0163383	0.0108580
R-HSA-112043	PLC beta mediated events	50	2.001917	0.0163383	0.0108580
R-HSA-212676	Dopamine Neurotransmitter Release Cycle	22	1.998753	0.0319771	0.0212511
R-HSA-1362409	Mitochondrial iron-sulfur cluster biogenesis	12	1.997021	0.0163383	0.0108580
R-HSA-210500	Glutamate Neurotransmitter Release Cycle	24	1.992552	0.0245170	0.0162933
R-HSA-5610783	Degradation of GLI2 by the proteasome	57	1.979908	0.0163383	0.0108580
R-HSA-442742	CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	29	1.978334	0.0245170	0.0162933
R-HSA-8951664	Neddylation	225	1.976975	0.0163383	0.0108580
R-HSA-9609736	Assembly and cell surface presentation of NMDA receptors	34	1.976486	0.0245170	0.0162933
R-HSA-442720	CREB1 phosphorylation through the activation of Adenylate Cyclase	13	1.975404	0.0163383	0.0108580
R-HSA-5610780	Degradation of GLI1 by the proteasome	57	1.971102	0.0163383	0.0108580
R-HSA-5578775	Ion homeostasis	53	1.970579	0.0163383	0.0108580
R-HSA-112040	G-protein mediated events	51	1.967535	0.0163383	0.0108580
R-HSA-5576891	Cardiac conduction	131	1.954009	0.0163383	0.0108580
R-HSA-5099900	WNT5A-dependent internalization of FZD4	15	1.945404	0.0245170	0.0162933
R-HSA-169911	Regulation of Apoptosis	51	1.941266	0.0163383	0.0108580
R-HSA-8939902	Regulation of RUNX2 expression and activity	70	1.938164	0.0163383	0.0108580
R-HSA-5676590	NIK–>noncanonical NF-kB signaling	56	1.936767	0.0163383	0.0108580
R-HSA-163685	Integration of energy metabolism	101	1.933458	0.0163383	0.0108580
R-HSA-174084	Autodegradation of Cdh1 by Cdh1:APC/C	62	1.927796	0.0163383	0.0108580
R-HSA-68867	Assembly of the pre-replicative complex	65	1.926250	0.0163383	0.0108580
R-HSA-5210891	Uptake and function of anthrax toxins	13	1.926208	0.0245170	0.0162933
R-HSA-5610785	GLI3 is processed to GLI3R by the proteasome	57	1.922772	0.0163383	0.0108580
R-HSA-68827	CDT1 association with the CDC6:ORC:origin complex	57	1.921878	0.0163383	0.0108580
R-HSA-6811436	COPI-independent Golgi-to-ER retrograde traffic	45	1.915043	0.0163383	0.0108580
R-HSA-180585	Vif-mediated degradation of APOBEC3G	52	1.913775	0.0245170	0.0162933
R-HSA-379724	tRNA Aminoacylation	42	1.913478	0.0248666	0.0165257
R-HSA-451306	Ionotropic activity of kainate receptors	12	1.906336	0.0245170	0.0162933
R-HSA-451308	Activation of Ca-permeable Kainate Receptor	12	1.906336	0.0245170	0.0162933
R-HSA-181429	Serotonin Neurotransmitter Release Cycle	17	1.903568	0.0163383	0.0108580
R-HSA-1592230	Mitochondrial biogenesis	94	1.903230	0.0163383	0.0108580
R-HSA-75815	Ubiquitin-dependent degradation of Cyclin D	50	1.900190	0.0163383	0.0108580
R-HSA-211733	Regulation of activated PAK-2p34 by proteasome mediated degradation	48	1.899298	0.0163383	0.0108580
R-HSA-69601	Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	50	1.897284	0.0163383	0.0108580
R-HSA-69610	p53-Independent DNA Damage Response	50	1.897284	0.0163383	0.0108580
R-HSA-69613	p53-Independent G1/S DNA damage checkpoint	50	1.897284	0.0163383	0.0108580
R-HSA-163210	Formation of ATP by chemiosmotic coupling	18	1.896052	0.0319771	0.0212511
R-HSA-177504	Retrograde neurotrophin signalling	14	1.894044	0.0245170	0.0162933
R-HSA-5610787	Hedgehog ‘off’ state	108	1.890758	0.0163383	0.0108580
R-HSA-8856688	Golgi-to-ER retrograde transport	124	1.890283	0.0163383	0.0108580
R-HSA-8948751	Regulation of PTEN stability and activity	67	1.888547	0.0163383	0.0108580
R-HSA-5362768	Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD	54	1.883881	0.0245170	0.0162933
R-HSA-8949215	Mitochondrial calcium ion transport	23	1.881357	0.0245170	0.0162933
R-HSA-70263	Gluconeogenesis	29	1.878854	0.0245170	0.0162933
R-HSA-422356	Regulation of insulin secretion	73	1.875978	0.0163383	0.0108580
R-HSA-6794362	Protein-protein interactions at synapses	87	1.870723	0.0163383	0.0108580
R-HSA-8849932	Synaptic adhesion-like molecules	21	1.869932	0.0383797	0.0255061
R-HSA-8949664	Processing of SMDT1	16	1.869291	0.0245170	0.0162933
R-HSA-8854050	FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	52	1.867612	0.0245170	0.0162933
R-HSA-264642	Acetylcholine Neurotransmitter Release Cycle	14	1.859296	0.0245170	0.0162933
R-HSA-77387	Insulin receptor recycling	23	1.858300	0.0319771	0.0212511
R-HSA-5607761	Dectin-1 mediated noncanonical NF-kB signaling	57	1.857786	0.0163383	0.0108580
R-HSA-180534	Vpu mediated degradation of CD4	50	1.853985	0.0163383	0.0108580
R-HSA-4086400	PCP/CE pathway	89	1.836665	0.0163383	0.0108580
R-HSA-349425	Autodegradation of the E3 ubiquitin ligase COP1	50	1.832836	0.0245170	0.0162933
R-HSA-174113	SCF-beta-TrCP mediated degradation of Emi1	53	1.831612	0.0245170	0.0162933
R-HSA-5387390	Hh mutants abrogate ligand secretion	56	1.826422	0.0245170	0.0162933
R-HSA-1168372	Downstream signaling events of B Cell Receptor (BCR)	81	1.816836	0.0245170	0.0162933
R-HSA-1222556	ROS and RNS production in phagocytes	34	1.813762	0.0245170	0.0162933
R-HSA-111931	PKA-mediated phosphorylation of CREB	20	1.812149	0.0440225	0.0292561
R-HSA-4641257	Degradation of AXIN	53	1.807226	0.0245170	0.0162933
R-HSA-917977	Transferrin endocytosis and recycling	29	1.805510	0.0319771	0.0212511
R-HSA-5658442	Regulation of RAS by GAPs	66	1.805475	0.0163383	0.0108580
R-HSA-8854214	TBC/RABGAPs	44	1.791965	0.0163383	0.0108580
R-HSA-3858494	Beta-catenin independent WNT signaling	139	1.791632	0.0163383	0.0108580
R-HSA-174154	APC/C:Cdc20 mediated degradation of Securin	64	1.790568	0.0245170	0.0162933
R-HSA-1632852	Macroautophagy	91	1.789106	0.0163383	0.0108580
R-HSA-112308	Presynaptic depolarization and calcium channel opening	13	1.777247	0.0383797	0.0255061
R-HSA-164378	PKA activation in glucagon signalling	16	1.770856	0.0440225	0.0292561
R-HSA-373760	L1CAM interactions	111	1.764163	0.0163383	0.0108580
R-HSA-70326	Glucose metabolism	85	1.761742	0.0245170	0.0162933
R-HSA-2132295	MHC class II antigen presentation	110	1.755864	0.0163383	0.0108580
R-HSA-69052	Switching of origins to a post-replicative state	87	1.750889	0.0245170	0.0162933
R-HSA-69017	CDK-mediated phosphorylation and removal of Cdc6	69	1.750688	0.0163383	0.0108580
R-HSA-68949	Orc1 removal from chromatin	69	1.746567	0.0163383	0.0108580
R-HSA-181430	Norepinephrine Neurotransmitter Release Cycle	18	1.746453	0.0381679	0.0253653
R-HSA-8941858	Regulation of RUNX3 expression and activity	55	1.741963	0.0319771	0.0212511
R-HSA-195253	Degradation of beta-catenin by the destruction complex	80	1.741499	0.0245170	0.0162933
R-HSA-69541	Stabilization of p53	55	1.737300	0.0319771	0.0212511
R-HSA-451326	Activation of kainate receptors upon glutamate binding	31	1.736232	0.0441783	0.0293597
R-HSA-174178	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	67	1.734365	0.0319771	0.0212511
R-HSA-1852241	Organelle biogenesis and maintenance	286	1.730745	0.0163383	0.0108580
R-HSA-70268	Pyruvate metabolism	28	1.728660	0.0440225	0.0292561
R-HSA-380972	Energy dependent regulation of mTOR by LKB1-AMPK	28	1.727284	0.0440225	0.0292561
R-HSA-74752	Signaling by Insulin receptor	66	1.726672	0.0383797	0.0255061
R-HSA-179419	APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	70	1.711435	0.0245170	0.0162933
R-HSA-9007101	Rab regulation of trafficking	122	1.711344	0.0163383	0.0108580
R-HSA-9005891	Loss of function of MECP2 in Rett syndrome	14	1.710397	0.0495196	0.0329093
R-HSA-9005895	Pervasive developmental disorders	14	1.710397	0.0495196	0.0329093
R-HSA-418359	Reduction of cytosolic Ca++ levels	14	1.708907	0.0495196	0.0329093
R-HSA-174184	Cdc20:Phospho-APC/C mediated degradation of Cyclin A	69	1.707665	0.0245170	0.0162933
R-HSA-6807878	COPI-mediated anterograde transport	92	1.706563	0.0163383	0.0108580
R-HSA-5607763	CLEC7A (Dectin-1) induces NFAT activation	13	1.705175	0.0440225	0.0292561
R-HSA-69002	DNA Replication Pre-Initiation	82	1.700688	0.0245170	0.0162933
R-HSA-8856828	Clathrin-mediated endocytosis	137	1.696411	0.0163383	0.0108580
R-HSA-5607764	CLEC7A (Dectin-1) signaling	98	1.694394	0.0319771	0.0212511
R-HSA-176409	APC/C:Cdc20 mediated degradation of mitotic proteins	72	1.693267	0.0163383	0.0108580
R-HSA-176814	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	72	1.693267	0.0163383	0.0108580
R-HSA-8852276	The role of GTSE1 in G2/M progression after G2 checkpoint	69	1.690602	0.0319771	0.0212511
R-HSA-382556	ABC-family proteins mediated transport	100	1.689007	0.0319771	0.0212511
R-HSA-8856825	Cargo recognition for clathrin-mediated endocytosis	97	1.676854	0.0319771	0.0212511
R-HSA-2454202	Fc epsilon receptor (FCERI) signaling	129	1.676732	0.0163383	0.0108580
R-HSA-176408	Regulation of APC/C activators between G1/S and early anaphase	76	1.676132	0.0245170	0.0162933
R-HSA-445717	Aquaporin-mediated transport	44	1.674538	0.0387468	0.0257500
R-HSA-187577	SCF(Skp2)-mediated degradation of p27/p21	60	1.666134	0.0319771	0.0212511
R-HSA-5358346	Hedgehog ligand biogenesis	62	1.662053	0.0383797	0.0255061
R-HSA-5673001	RAF/MAP kinase cascade	224	1.661475	0.0163383	0.0108580
R-HSA-432040	Vasopressin regulates renal water homeostasis via Aquaporins	38	1.655159	0.0383797	0.0255061
R-HSA-9006925	Intracellular signaling by second messengers	285	1.654087	0.0163383	0.0108580
R-HSA-4608870	Asymmetric localization of PCP proteins	62	1.645004	0.0383797	0.0255061
R-HSA-381676	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	39	1.640102	0.0387468	0.0257500
R-HSA-69563	p53-Dependent G1 DNA Damage Response	64	1.639945	0.0442887	0.0294330
R-HSA-69580	p53-Dependent G1/S DNA damage checkpoint	64	1.639945	0.0442887	0.0294330
R-HSA-6811434	COPI-dependent Golgi-to-ER retrograde traffic	91	1.638914	0.0319771	0.0212511
R-HSA-380270	Recruitment of mitotic centrosome proteins and complexes	79	1.636608	0.0319771	0.0212511
R-HSA-380287	Centrosome maturation	79	1.636608	0.0319771	0.0212511
R-HSA-453274	Mitotic G2-G2/M phases	187	1.630348	0.0163383	0.0108580
R-HSA-983168	Antigen processing: Ubiquitination & Proteasome degradation	296	1.630228	0.0163383	0.0108580
R-HSA-5621481	C-type lectin receptors (CLRs)	123	1.629426	0.0163383	0.0108580
R-HSA-1483255	PI Metabolism	82	1.628843	0.0319771	0.0212511
R-HSA-936837	Ion transport by P-type ATPases	54	1.617549	0.0384958	0.0255832
R-HSA-5619084	ABC transporter disorders	75	1.615030	0.0319771	0.0212511
R-HSA-69615	G1/S DNA Damage Checkpoints	66	1.613393	0.0383797	0.0255061
R-HSA-69275	G2/M Transition	185	1.605572	0.0163383	0.0108580
R-HSA-5684996	MAPK1/MAPK3 signaling	230	1.597186	0.0163383	0.0108580
R-HSA-5358351	Signaling by Hedgehog	143	1.596534	0.0163383	0.0108580
R-HSA-2871837	FCERI mediated NF-kB activation	78	1.593279	0.0383797	0.0255061
R-HSA-450408	AUF1 (hnRNP D0) binds and destabilizes mRNA	54	1.591723	0.0496247	0.0329792
R-HSA-5678895	Defective CFTR causes cystic fibrosis	59	1.580100	0.0319771	0.0212511
R-HSA-70171	Glycolysis	68	1.577632	0.0440225	0.0292561
R-HSA-162909	Host Interactions of HIV factors	125	1.575720	0.0245170	0.0162933
R-HSA-6794361	Neurexins and neuroligins	56	1.574817	0.0440225	0.0292561
R-HSA-8986944	Transcriptional Regulation by MECP2	61	1.563358	0.0441783	0.0293597
R-HSA-69202	Cyclin E associated events during G1/S transition	83	1.562412	0.0495196	0.0329093
R-HSA-380320	Recruitment of NuMA to mitotic centrosomes	86	1.552969	0.0495196	0.0329093
R-HSA-983712	Ion channel transport	168	1.520687	0.0163383	0.0108580
R-HSA-397014	Muscle contraction	187	1.513686	0.0163383	0.0108580
R-HSA-6811442	Intra-Golgi and retrograde Golgi-to-ER traffic	191	1.490328	0.0319413	0.0212273
R-HSA-199977	ER to Golgi Anterograde Transport	142	1.478753	0.0319771	0.0212511
R-HSA-162906	HIV Infection	224	1.450722	0.0245170	0.0162933
R-HSA-5683057	MAPK family signaling cascades	266	1.433513	0.0163383	0.0108580
R-HSA-69481	G2/M Checkpoints	162	1.433334	0.0434028	0.0288443
R-HSA-195721	Signaling by WNT	309	1.385512	0.0319771	0.0212511

rm(df)

Gene Ontology

for(module in top_modules){
  df = enrichment_GO[[module]] %>% dplyr::select(ID, Description, setSize, NES, p.adjust, qvalues) %>% arrange(desc(NES)) %>% filter(NES>0)
  if(nrow(df)>0){
    print(kable(df, caption = paste0('Enriched terms for module ', module, ' (MTcor = ', round(dataset$MTcor[dataset$Module==module][1],2),')')))
    cat('\n') 
  } else cat(paste0('\nNo enrichment found for module ',module,'\n'))
}

Enriched terms for module #00B9E3 (MTcor = -0.93)

ID	Description	setSize	NES	p.adjust	qvalues
GO:0042775	mitochondrial ATP synthesis coupled electron transport	87	2.752686	0.0329885	0.0231737
GO:0042773	ATP synthesis coupled electron transport	88	2.726014	0.0329885	0.0231737
GO:0098693	regulation of synaptic vesicle cycle	105	2.684098	0.0329885	0.0231737
GO:1900449	regulation of glutamate receptor signaling pathway	54	2.666107	0.0329885	0.0231737
GO:0099504	synaptic vesicle cycle	158	2.665682	0.0329885	0.0231737
GO:0022904	respiratory electron transport chain	104	2.661921	0.0329885	0.0231737
GO:0007269	neurotransmitter secretion	142	2.655961	0.0329885	0.0231737
GO:0099643	signal release from synapse	143	2.645728	0.0329885	0.0231737
GO:0099003	vesicle-mediated transport in synapse	171	2.630220	0.0329885	0.0231737
GO:2000310	regulation of NMDA receptor activity	33	2.616300	0.0329885	0.0231737
GO:0016079	synaptic vesicle exocytosis	99	2.597362	0.0329885	0.0231737
GO:1902803	regulation of synaptic vesicle transport	75	2.562522	0.0329885	0.0231737
GO:0048489	synaptic vesicle transport	125	2.552998	0.0329885	0.0231737
GO:0097480	establishment of synaptic vesicle localization	125	2.552998	0.0329885	0.0231737
GO:0017156	calcium ion regulated exocytosis	124	2.551871	0.0329885	0.0231737
GO:0097479	synaptic vesicle localization	135	2.549518	0.0329885	0.0231737
GO:0099601	regulation of neurotransmitter receptor activity	62	2.546387	0.0329885	0.0231737
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	54	2.543747	0.0329885	0.0231737
GO:0046928	regulation of neurotransmitter secretion	93	2.537430	0.0329885	0.0231737
GO:2001257	regulation of cation channel activity	150	2.525697	0.0329885	0.0231737
GO:0036465	synaptic vesicle recycling	49	2.514152	0.0329885	0.0231737
GO:0017158	regulation of calcium ion-dependent exocytosis	90	2.499577	0.0329885	0.0231737
GO:2000300	regulation of synaptic vesicle exocytosis	70	2.488736	0.0329885	0.0231737
GO:0007215	glutamate receptor signaling pathway	81	2.478794	0.0329885	0.0231737
GO:0045333	cellular respiration	171	2.466633	0.0329885	0.0231737
GO:0006119	oxidative phosphorylation	128	2.447293	0.0329885	0.0231737
GO:0032412	regulation of ion transmembrane transporter activity	213	2.443186	0.0329885	0.0231737
GO:0048168	regulation of neuronal synaptic plasticity	46	2.436418	0.0329885	0.0231737
GO:0051588	regulation of neurotransmitter transport	124	2.428839	0.0329885	0.0231737
GO:0006836	neurotransmitter transport	222	2.425062	0.0329885	0.0231737
GO:0048167	regulation of synaptic plasticity	163	2.421073	0.0329885	0.0231737
GO:0010257	NADH dehydrogenase complex assembly	64	2.415002	0.0329885	0.0231737
GO:0032981	mitochondrial respiratory chain complex I assembly	64	2.415002	0.0329885	0.0231737
GO:0022898	regulation of transmembrane transporter activity	220	2.403669	0.0329885	0.0231737
GO:0032594	protein transport within lipid bilayer	20	2.403186	0.0329885	0.0231737
GO:1903421	regulation of synaptic vesicle recycling	24	2.383206	0.0329885	0.0231737
GO:0032409	regulation of transporter activity	231	2.362543	0.0329885	0.0231737
GO:0098877	neurotransmitter receptor transport to plasma membrane	12	2.357005	0.0329885	0.0231737
GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	12	2.357005	0.0329885	0.0231737
GO:0106027	neuron projection organization	83	2.356722	0.0329885	0.0231737
GO:0099177	regulation of trans-synaptic signaling	375	2.356608	0.0329885	0.0231737
GO:0050804	modulation of chemical synaptic transmission	374	2.355858	0.0329885	0.0231737
GO:1903540	establishment of protein localization to postsynaptic membrane	13	2.354112	0.0329885	0.0231737
GO:0060997	dendritic spine morphogenesis	55	2.344730	0.0329885	0.0231737
GO:0061001	regulation of dendritic spine morphogenesis	42	2.339339	0.0329885	0.0231737
GO:0048169	regulation of long-term neuronal synaptic plasticity	25	2.312561	0.0329885	0.0231737
GO:0048488	synaptic vesicle endocytosis	37	2.306396	0.0329885	0.0231737
GO:0140238	presynaptic endocytosis	37	2.306396	0.0329885	0.0231737
GO:0061003	positive regulation of dendritic spine morphogenesis	20	2.302480	0.0329885	0.0231737
GO:0051650	establishment of vesicle localization	245	2.300951	0.0329885	0.0231737
GO:0051648	vesicle localization	261	2.295127	0.0329885	0.0231737
GO:0099632	protein transport within plasma membrane	13	2.281090	0.0329885	0.0231737
GO:0099637	neurotransmitter receptor transport	13	2.281090	0.0329885	0.0231737
GO:0014047	glutamate secretion	41	2.253292	0.0329885	0.0231737
GO:0097061	dendritic spine organization	75	2.231333	0.0329885	0.0231737
GO:0015672	monovalent inorganic cation transport	407	2.231038	0.0329885	0.0231737
GO:0034765	regulation of ion transmembrane transport	408	2.228250	0.0329885	0.0231737
GO:1902600	proton transmembrane transport	128	2.224872	0.0329885	0.0231737
GO:0060078	regulation of postsynaptic membrane potential	119	2.216082	0.0329885	0.0231737
GO:1904062	regulation of cation transmembrane transport	283	2.205013	0.0329885	0.0231737
GO:0022900	electron transport chain	162	2.198388	0.0329885	0.0231737
GO:1903008	organelle disassembly	78	2.195911	0.0329885	0.0231737
GO:0006101	citrate metabolic process	28	2.194922	0.0329885	0.0231737
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	67	2.184075	0.0329885	0.0231737
GO:2001259	positive regulation of cation channel activity	63	2.178469	0.0329885	0.0231737
GO:0006813	potassium ion transport	169	2.177620	0.0329885	0.0231737
GO:0000422	autophagy of mitochondrion	55	2.159412	0.0329885	0.0231737
GO:0061726	mitochondrion disassembly	55	2.159412	0.0329885	0.0231737
GO:0009060	aerobic respiration	66	2.158508	0.0329885	0.0231737
GO:0071804	cellular potassium ion transport	121	2.155527	0.0329885	0.0231737
GO:0071805	potassium ion transmembrane transport	121	2.155527	0.0329885	0.0231737
GO:0023061	signal release	380	2.154357	0.0329885	0.0231737
GO:0098814	spontaneous synaptic transmission	11	2.149657	0.0329885	0.0231737
GO:0007612	learning	137	2.143456	0.0329885	0.0231737
GO:0008306	associative learning	73	2.138620	0.0329885	0.0231737
GO:0050808	synapse organization	378	2.136757	0.0329885	0.0231737
GO:0072384	organelle transport along microtubule	71	2.132737	0.0329885	0.0231737
GO:0016082	synaptic vesicle priming	12	2.132542	0.0329885	0.0231737
GO:0001963	synaptic transmission, dopaminergic	24	2.131702	0.0329885	0.0231737
GO:0033108	mitochondrial respiratory chain complex assembly	87	2.128374	0.0329885	0.0231737
GO:0015980	energy derivation by oxidation of organic compounds	251	2.124345	0.0329885	0.0231737
GO:1901524	regulation of mitophagy	17	2.117759	0.0329885	0.0231737
GO:0007611	learning or memory	229	2.114837	0.0329885	0.0231737
GO:0034762	regulation of transmembrane transport	475	2.113879	0.0329885	0.0231737
GO:0006099	tricarboxylic acid cycle	26	2.113357	0.0329885	0.0231737
GO:0031111	negative regulation of microtubule polymerization or depolymerization	32	2.105158	0.0329885	0.0231737
GO:0035637	multicellular organismal signaling	176	2.104921	0.0329885	0.0231737
GO:0033238	regulation of cellular amine metabolic process	74	2.103478	0.0329885	0.0231737
GO:0017157	regulation of exocytosis	181	2.100406	0.0329885	0.0231737
GO:0060996	dendritic spine development	93	2.098832	0.0329885	0.0231737
GO:0050775	positive regulation of dendrite morphogenesis	35	2.095214	0.0329885	0.0231737
GO:0099132	ATP hydrolysis coupled cation transmembrane transport	52	2.090769	0.0329885	0.0231737
GO:0045653	negative regulation of megakaryocyte differentiation	17	2.088769	0.0329885	0.0231737
GO:0097484	dendrite extension	32	2.088652	0.0329885	0.0231737
GO:0046034	ATP metabolic process	274	2.085203	0.0329885	0.0231737
GO:0009126	purine nucleoside monophosphate metabolic process	304	2.080307	0.0329885	0.0231737
GO:0048172	regulation of short-term neuronal synaptic plasticity	12	2.079671	0.0329885	0.0231737
GO:0038095	Fc-epsilon receptor signaling pathway	106	2.079635	0.0329885	0.0231737
GO:0035418	protein localization to synapse	55	2.079553	0.0329885	0.0231737
GO:0042391	regulation of membrane potential	338	2.079527	0.0329885	0.0231737
GO:0007007	inner mitochondrial membrane organization	37	2.078651	0.0329885	0.0231737
GO:0007005	mitochondrion organization	452	2.075925	0.0329885	0.0231737
GO:0042407	cristae formation	30	2.075763	0.0329885	0.0231737
GO:0009205	purine ribonucleoside triphosphate metabolic process	300	2.074523	0.0329885	0.0231737
GO:0035641	locomotory exploration behavior	12	2.074474	0.0329885	0.0231737
GO:0009167	purine ribonucleoside monophosphate metabolic process	303	2.073122	0.0329885	0.0231737
GO:0050905	neuromuscular process	87	2.072795	0.0329885	0.0231737
GO:1903305	regulation of regulated secretory pathway	134	2.070448	0.0329885	0.0231737
GO:0009199	ribonucleoside triphosphate metabolic process	305	2.065402	0.0329885	0.0231737
GO:0048813	dendrite morphogenesis	130	2.062597	0.0329885	0.0231737
GO:0009161	ribonucleoside monophosphate metabolic process	316	2.062330	0.0329885	0.0231737
GO:0060998	regulation of dendritic spine development	70	2.056195	0.0329885	0.0231737
GO:0051952	regulation of amine transport	63	2.055964	0.0329885	0.0231737
GO:0009144	purine nucleoside triphosphate metabolic process	307	2.054471	0.0329885	0.0231737
GO:0007006	mitochondrial membrane organization	115	2.053742	0.0329885	0.0231737
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	37	2.053205	0.0329885	0.0231737
GO:0032414	positive regulation of ion transmembrane transporter activity	94	2.050044	0.0329885	0.0231737
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	57	2.050026	0.0329885	0.0231737
GO:1903539	protein localization to postsynaptic membrane	27	2.049038	0.0329885	0.0231737
GO:0035640	exploration behavior	23	2.047852	0.0329885	0.0231737
GO:0045956	positive regulation of calcium ion-dependent exocytosis	22	2.044626	0.0329885	0.0231737
GO:0001505	regulation of neurotransmitter levels	289	2.044403	0.0329885	0.0231737
GO:0048667	cell morphogenesis involved in neuron differentiation	469	2.041336	0.0329885	0.0231737
GO:0060999	positive regulation of dendritic spine development	41	2.037936	0.0329885	0.0231737
GO:0048814	regulation of dendrite morphogenesis	81	2.037870	0.0329885	0.0231737
GO:0009123	nucleoside monophosphate metabolic process	332	2.034644	0.0329885	0.0231737
GO:0010765	positive regulation of sodium ion transport	29	2.033345	0.0329885	0.0231737
GO:0051965	positive regulation of synapse assembly	62	2.032590	0.0329885	0.0231737
GO:1903146	regulation of autophagy of mitochondrion	41	2.032109	0.0329885	0.0231737
GO:0000266	mitochondrial fission	30	2.029498	0.0329885	0.0231737
GO:1903533	regulation of protein targeting	79	2.026574	0.0329885	0.0231737
GO:0015837	amine transport	66	2.025659	0.0329885	0.0231737
GO:0051705	multi-organism behavior	60	2.022718	0.0329885	0.0231737
GO:1903859	regulation of dendrite extension	23	2.019414	0.0329885	0.0231737
GO:0009141	nucleoside triphosphate metabolic process	323	2.017744	0.0329885	0.0231737
GO:0015800	acidic amino acid transport	60	2.017187	0.0329885	0.0231737
GO:1990138	neuron projection extension	141	2.016415	0.0329885	0.0231737
GO:1903779	regulation of cardiac conduction	65	2.015895	0.0329885	0.0231737
GO:0000423	mitophagy	21	2.011547	0.0329885	0.0231737
GO:0061337	cardiac conduction	135	2.011043	0.0329885	0.0231737
GO:0050803	regulation of synapse structure or activity	211	2.008698	0.0329885	0.0231737
GO:0051932	synaptic transmission, GABAergic	36	2.008470	0.0329885	0.0231737
GO:0010976	positive regulation of neuron projection development	249	2.007464	0.0329885	0.0231737
GO:0050806	positive regulation of synaptic transmission	138	2.005569	0.0329885	0.0231737
GO:0097120	receptor localization to synapse	35	2.003388	0.0329885	0.0231737
GO:0070050	neuron cellular homeostasis	30	2.001539	0.0329885	0.0231737
GO:0050432	catecholamine secretion	36	1.999757	0.0329885	0.0231737
GO:0006626	protein targeting to mitochondrion	84	1.995634	0.0329885	0.0231737
GO:0051646	mitochondrion localization	41	1.995059	0.0329885	0.0231737
GO:0042551	neuron maturation	42	1.995024	0.0329885	0.0231737
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	47	1.994632	0.0329885	0.0231737
GO:0007626	locomotory behavior	171	1.990999	0.0329885	0.0231737
GO:0070585	protein localization to mitochondrion	123	1.990260	0.0329885	0.0231737
GO:0035249	synaptic transmission, glutamatergic	60	1.989865	0.0329885	0.0231737
GO:0007409	axonogenesis	364	1.989650	0.0329885	0.0231737
GO:0051937	catecholamine transport	48	1.989540	0.0329885	0.0231737
GO:0072350	tricarboxylic acid metabolic process	31	1.987657	0.0329885	0.0231737
GO:0072583	clathrin-dependent endocytosis	37	1.983597	0.0329885	0.0231737
GO:0050770	regulation of axonogenesis	143	1.983039	0.0329885	0.0231737
GO:0034643	establishment of mitochondrion localization, microtubule-mediated	18	1.982571	0.0329885	0.0231737
GO:0047497	mitochondrion transport along microtubule	18	1.982571	0.0329885	0.0231737
GO:0043950	positive regulation of cAMP-mediated signaling	19	1.982362	0.0329885	0.0231737
GO:0051963	regulation of synapse assembly	99	1.982270	0.0329885	0.0231737
GO:0051656	establishment of organelle localization	426	1.981614	0.0329885	0.0231737
GO:0032411	positive regulation of transporter activity	102	1.980314	0.0329885	0.0231737
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	17	1.977501	0.0329885	0.0231737
GO:0010970	transport along microtubule	141	1.976551	0.0329885	0.0231737
GO:0099111	microtubule-based transport	141	1.976551	0.0329885	0.0231737
GO:0072655	establishment of protein localization to mitochondrion	120	1.975209	0.0329885	0.0231737
GO:0007416	synapse assembly	163	1.974775	0.0329885	0.0231737
GO:0030705	cytoskeleton-dependent intracellular transport	152	1.969909	0.0329885	0.0231737
GO:0050890	cognition	261	1.967167	0.0329885	0.0231737
GO:0016241	regulation of macroautophagy	161	1.964031	0.0329885	0.0231737
GO:1900242	regulation of synaptic vesicle endocytosis	16	1.963537	0.0329885	0.0231737
GO:0051654	establishment of mitochondrion localization	21	1.960714	0.0329885	0.0231737
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	17	1.959332	0.0329885	0.0231737
GO:0019646	aerobic electron transport chain	17	1.959332	0.0329885	0.0231737
GO:0061564	axon development	403	1.956203	0.0329885	0.0231737
GO:0032402	melanosome transport	19	1.955188	0.0372897	0.0261952
GO:0045161	neuronal ion channel clustering	11	1.953780	0.0329885	0.0231737
GO:0050433	regulation of catecholamine secretion	34	1.952564	0.0361638	0.0254042
GO:0050807	regulation of synapse organization	207	1.951989	0.0329885	0.0231737
GO:0010822	positive regulation of mitochondrion organization	113	1.951196	0.0329885	0.0231737
GO:2000649	regulation of sodium ion transmembrane transporter activity	38	1.951137	0.0329885	0.0231737
GO:0035725	sodium ion transmembrane transport	92	1.942098	0.0329885	0.0231737
GO:0010975	regulation of neuron projection development	433	1.936125	0.0329885	0.0231737
GO:0009150	purine ribonucleotide metabolic process	471	1.935344	0.0329885	0.0231737
GO:0048308	organelle inheritance	13	1.932428	0.0329885	0.0231737
GO:0048313	Golgi inheritance	13	1.932428	0.0329885	0.0231737
GO:0009259	ribonucleotide metabolic process	485	1.929754	0.0329885	0.0231737
GO:0006734	NADH metabolic process	34	1.926405	0.0361638	0.0254042
GO:0019226	transmission of nerve impulse	46	1.925135	0.0361638	0.0254042
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	12	1.924772	0.0329885	0.0231737
GO:0018210	peptidyl-threonine modification	103	1.923904	0.0329885	0.0231737
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	50	1.922104	0.0361638	0.0254042
GO:0000338	protein deneddylation	10	1.920473	0.0332231	0.0233385
GO:0032225	regulation of synaptic transmission, dopaminergic	15	1.919432	0.0372328	0.0261552
GO:0015991	ATP hydrolysis coupled proton transport	24	1.917065	0.0365558	0.0256796
GO:0060079	excitatory postsynaptic potential	88	1.916596	0.0329885	0.0231737
GO:0033173	calcineurin-NFAT signaling cascade	35	1.915508	0.0361638	0.0254042
GO:0097720	calcineurin-mediated signaling	35	1.915508	0.0361638	0.0254042
GO:0006091	generation of precursor metabolites and energy	464	1.915246	0.0329885	0.0231737
GO:0015985	energy coupled proton transport, down electrochemical gradient	22	1.915053	0.0370308	0.0260133
GO:0015986	ATP synthesis coupled proton transport	22	1.915053	0.0370308	0.0260133
GO:0099173	postsynapse organization	154	1.915023	0.0329885	0.0231737
GO:0099188	postsynaptic cytoskeleton organization	10	1.913675	0.0332231	0.0233385
GO:0042537	benzene-containing compound metabolic process	18	1.913102	0.0329885	0.0231737
GO:0010644	cell communication by electrical coupling	29	1.912673	0.0329885	0.0231737
GO:0006883	cellular sodium ion homeostasis	12	1.912650	0.0329885	0.0231737
GO:0045666	positive regulation of neuron differentiation	321	1.911493	0.0329885	0.0231737
GO:0090140	regulation of mitochondrial fission	23	1.910528	0.0418253	0.0293813
GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	25	1.910508	0.0364581	0.0256110
GO:0051954	positive regulation of amine transport	30	1.910092	0.0364581	0.0256110
GO:0099131	ATP hydrolysis coupled ion transmembrane transport	26	1.908546	0.0329885	0.0231737
GO:0007026	negative regulation of microtubule depolymerization	21	1.902486	0.0418288	0.0293838
GO:0035235	ionotropic glutamate receptor signaling pathway	23	1.902453	0.0418253	0.0293813
GO:0006163	purine nucleotide metabolic process	493	1.901963	0.0329885	0.0231737
GO:0006839	mitochondrial transport	215	1.901035	0.0329885	0.0231737
GO:0071322	cellular response to carbohydrate stimulus	122	1.900792	0.0329885	0.0231737
GO:0007632	visual behavior	47	1.899945	0.0361638	0.0254042
GO:0043266	regulation of potassium ion transport	83	1.898484	0.0329885	0.0231737
GO:0006007	glucose catabolic process	33	1.893309	0.0361638	0.0254042
GO:0032400	melanosome localization	23	1.891257	0.0418253	0.0293813
GO:0018107	peptidyl-threonine phosphorylation	95	1.891067	0.0329885	0.0231737
GO:0051904	pigment granule transport	20	1.889613	0.0371078	0.0260674
GO:0001508	action potential	108	1.883125	0.0329885	0.0231737
GO:0099565	chemical synaptic transmission, postsynaptic	96	1.882913	0.0329885	0.0231737
GO:0098930	axonal transport	50	1.882348	0.0361638	0.0254042
GO:0099518	vesicle cytoskeletal trafficking	43	1.882010	0.0329885	0.0231737
GO:0032401	establishment of melanosome localization	20	1.880900	0.0371078	0.0260674
GO:1903861	positive regulation of dendrite extension	21	1.879665	0.0418288	0.0293838
GO:0047496	vesicle transport along microtubule	38	1.879176	0.0361638	0.0254042
GO:0008542	visual learning	43	1.878617	0.0329885	0.0231737
GO:0007018	microtubule-based movement	215	1.877469	0.0329885	0.0231737
GO:0048588	developmental cell growth	194	1.877176	0.0329885	0.0231737
GO:0035306	positive regulation of dephosphorylation	51	1.875293	0.0361638	0.0254042
GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	14	1.874695	0.0422693	0.0296932
GO:0086010	membrane depolarization during action potential	24	1.873622	0.0365558	0.0256796
GO:0016358	dendrite development	212	1.872788	0.0329885	0.0231737
GO:0032252	secretory granule localization	12	1.870949	0.0372897	0.0261952
GO:0045773	positive regulation of axon extension	40	1.865765	0.0364733	0.0256217
GO:0045760	positive regulation of action potential	10	1.862002	0.0332231	0.0233385
GO:0043524	negative regulation of neuron apoptotic process	129	1.861224	0.0329885	0.0231737
GO:0031338	regulation of vesicle fusion	24	1.858766	0.0365558	0.0256796
GO:1901016	regulation of potassium ion transmembrane transporter activity	48	1.856563	0.0361638	0.0254042
GO:0051966	regulation of synaptic transmission, glutamatergic	48	1.856446	0.0361638	0.0254042
GO:1901379	regulation of potassium ion transmembrane transport	70	1.854265	0.0329885	0.0231737
GO:0021955	central nervous system neuron axonogenesis	33	1.853617	0.0361638	0.0254042
GO:0042776	mitochondrial ATP synthesis coupled proton transport	21	1.853299	0.0493475	0.0346655
GO:0005513	detection of calcium ion	11	1.851566	0.0329885	0.0231737
GO:0015872	dopamine transport	29	1.851506	0.0414464	0.0291152
GO:0031115	negative regulation of microtubule polymerization	12	1.850001	0.0372897	0.0261952
GO:1902305	regulation of sodium ion transmembrane transport	47	1.848530	0.0361638	0.0254042
GO:0051875	pigment granule localization	24	1.848487	0.0365558	0.0256796
GO:0051905	establishment of pigment granule localization	21	1.846098	0.0493475	0.0346655
GO:0014046	dopamine secretion	19	1.844211	0.0372897	0.0261952
GO:0014059	regulation of dopamine secretion	19	1.844211	0.0372897	0.0261952
GO:0006335	DNA replication-dependent nucleosome assembly	32	1.843980	0.0412551	0.0289807
GO:0034723	DNA replication-dependent nucleosome organization	32	1.843980	0.0412551	0.0289807
GO:0090662	ATP hydrolysis coupled transmembrane transport	27	1.842097	0.0414183	0.0290954
GO:0014075	response to amine	43	1.840971	0.0361638	0.0254042
GO:0050884	neuromuscular process controlling posture	12	1.840520	0.0372897	0.0261952
GO:0043039	tRNA aminoacylation	45	1.840516	0.0361638	0.0254042
GO:0046785	microtubule polymerization	65	1.838624	0.0329885	0.0231737
GO:2000311	regulation of AMPA receptor activity	18	1.838282	0.0373115	0.0262105
GO:0099500	vesicle fusion to plasma membrane	10	1.837430	0.0332231	0.0233385
GO:0043038	amino acid activation	46	1.835369	0.0361638	0.0254042
GO:0008344	adult locomotory behavior	66	1.832419	0.0329885	0.0231737
GO:0031110	regulation of microtubule polymerization or depolymerization	68	1.832100	0.0329885	0.0231737
GO:0099560	synaptic membrane adhesion	25	1.831498	0.0364581	0.0256110
GO:0071333	cellular response to glucose stimulus	112	1.830380	0.0329885	0.0231737
GO:0016236	macroautophagy	267	1.830115	0.0329885	0.0231737
GO:0007631	feeding behavior	70	1.829381	0.0329885	0.0231737
GO:0030516	regulation of axon extension	73	1.829230	0.0329885	0.0231737
GO:0006521	regulation of cellular amino acid metabolic process	56	1.828062	0.0329885	0.0231737
GO:1903818	positive regulation of voltage-gated potassium channel activity	13	1.827941	0.0424425	0.0298149
GO:0031346	positive regulation of cell projection organization	334	1.826776	0.0329885	0.0231737
GO:0071326	cellular response to monosaccharide stimulus	114	1.826581	0.0329885	0.0231737
GO:0071331	cellular response to hexose stimulus	114	1.826581	0.0329885	0.0231737
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	24	1.826574	0.0365558	0.0256796
GO:1902259	regulation of delayed rectifier potassium channel activity	15	1.826100	0.0495117	0.0347808
GO:0001967	suckling behavior	10	1.825988	0.0332231	0.0233385
GO:0008038	neuron recognition	36	1.824314	0.0361638	0.0254042
GO:0030534	adult behavior	120	1.823954	0.0329885	0.0231737
GO:0035864	response to potassium ion	12	1.823571	0.0372897	0.0261952
GO:0031114	regulation of microtubule depolymerization	23	1.823571	0.0418253	0.0293813
GO:0021954	central nervous system neuron development	73	1.822958	0.0329885	0.0231737
GO:0008088	axo-dendritic transport	60	1.822731	0.0399769	0.0280829
GO:0035307	positive regulation of protein dephosphorylation	39	1.820643	0.0364581	0.0256110
GO:0006814	sodium ion transport	160	1.820127	0.0329885	0.0231737
GO:0006103	2-oxoglutarate metabolic process	14	1.819521	0.0497435	0.0349437
GO:0043267	negative regulation of potassium ion transport	26	1.818268	0.0413027	0.0290142
GO:0031145	anaphase-promoting complex-dependent catabolic process	76	1.817985	0.0329885	0.0231737
GO:0006865	amino acid transport	122	1.817086	0.0329885	0.0231737
GO:0046717	acid secretion	91	1.817077	0.0329885	0.0231737
GO:0060627	regulation of vesicle-mediated transport	443	1.816982	0.0329885	0.0231737
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	78	1.816556	0.0329885	0.0231737
GO:1903747	regulation of establishment of protein localization to mitochondrion	70	1.815295	0.0329885	0.0231737
GO:0044106	cellular amine metabolic process	111	1.814096	0.0329885	0.0231737
GO:0099175	regulation of postsynapse organization	95	1.813649	0.0329885	0.0231737
GO:1903214	regulation of protein targeting to mitochondrion	44	1.812415	0.0361638	0.0254042
GO:0061615	glycolytic process through fructose-6-phosphate	27	1.810486	0.0470662	0.0330630
GO:0061620	glycolytic process through glucose-6-phosphate	27	1.810486	0.0470662	0.0330630
GO:0016242	negative regulation of macroautophagy	32	1.809182	0.0412551	0.0289807
GO:0006735	NADH regeneration	26	1.808499	0.0413027	0.0290142
GO:0061621	canonical glycolysis	26	1.808499	0.0413027	0.0290142
GO:0061718	glucose catabolic process to pyruvate	26	1.808499	0.0413027	0.0290142
GO:0006089	lactate metabolic process	11	1.808210	0.0424097	0.0297918
GO:0030073	insulin secretion	173	1.807628	0.0329885	0.0231737
GO:0007020	microtubule nucleation	20	1.806025	0.0371078	0.0260674
GO:1904064	positive regulation of cation transmembrane transport	126	1.803541	0.0329885	0.0231737
GO:0006851	mitochondrial calcium ion transmembrane transport	25	1.799711	0.0414464	0.0291152
GO:0045921	positive regulation of exocytosis	77	1.797803	0.0329885	0.0231737
GO:0014850	response to muscle activity	22	1.795749	0.0418253	0.0293813
GO:0015682	ferric iron transport	34	1.794657	0.0361638	0.0254042
GO:0033572	transferrin transport	34	1.794657	0.0361638	0.0254042
GO:0072512	trivalent inorganic cation transport	34	1.794657	0.0361638	0.0254042
GO:1901019	regulation of calcium ion transmembrane transporter activity	80	1.793652	0.0329885	0.0231737
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	23	1.791149	0.0418253	0.0293813
GO:0031109	microtubule polymerization or depolymerization	92	1.789393	0.0329885	0.0231737
GO:0008637	apoptotic mitochondrial changes	110	1.788843	0.0329885	0.0231737
GO:0030072	peptide hormone secretion	204	1.788405	0.0329885	0.0231737
GO:0007019	microtubule depolymerization	33	1.785194	0.0361638	0.0254042
GO:0010769	regulation of cell morphogenesis involved in differentiation	250	1.784852	0.0329885	0.0231737
GO:0007613	memory	105	1.784290	0.0329885	0.0231737
GO:0071871	response to epinephrine	15	1.784180	0.0495117	0.0347808
GO:1903307	positive regulation of regulated secretory pathway	47	1.783901	0.0361638	0.0254042
GO:0060359	response to ammonium ion	115	1.783650	0.0329885	0.0231737
GO:0002028	regulation of sodium ion transport	67	1.779401	0.0329885	0.0231737
GO:0015844	monoamine transport	59	1.779024	0.0399769	0.0280829
GO:0008016	regulation of heart contraction	215	1.777692	0.0329885	0.0231737
GO:0006835	dicarboxylic acid transport	85	1.776517	0.0329885	0.0231737
GO:0048675	axon extension	97	1.773955	0.0329885	0.0231737
GO:1901526	positive regulation of mitophagy	10	1.772817	0.0377405	0.0265118
GO:0071242	cellular response to ammonium ion	59	1.771362	0.0399769	0.0280829
GO:0009583	detection of light stimulus	54	1.770242	0.0452588	0.0317933
GO:1904427	positive regulation of calcium ion transmembrane transport	62	1.770031	0.0399769	0.0280829
GO:1901215	negative regulation of neuron death	181	1.768385	0.0329885	0.0231737
GO:0006418	tRNA aminoacylation for protein translation	42	1.767853	0.0361638	0.0254042
GO:0007413	axonal fasciculation	23	1.767492	0.0418253	0.0293813
GO:0106030	neuron projection fasciculation	23	1.767492	0.0418253	0.0293813
GO:0090313	regulation of protein targeting to membrane	34	1.766085	0.0361638	0.0254042
GO:0007616	long-term memory	32	1.764279	0.0412551	0.0289807
GO:0038093	Fc receptor signaling pathway	169	1.762124	0.0329885	0.0231737
GO:0021544	subpallium development	25	1.760856	0.0414464	0.0291152
GO:0098876	vesicle-mediated transport to the plasma membrane	67	1.760633	0.0361638	0.0254042
GO:0140029	exocytic process	61	1.758505	0.0399769	0.0280829
GO:0034767	positive regulation of ion transmembrane transport	137	1.757556	0.0329885	0.0231737
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	17	1.756141	0.0496223	0.0348585
GO:0010821	regulation of mitochondrion organization	170	1.755546	0.0329885	0.0231737
GO:0070588	calcium ion transmembrane transport	265	1.755267	0.0329885	0.0231737
GO:0042053	regulation of dopamine metabolic process	19	1.752472	0.0496223	0.0348585
GO:0042069	regulation of catecholamine metabolic process	19	1.752472	0.0496223	0.0348585
GO:0002223	stimulatory C-type lectin receptor signaling pathway	93	1.750958	0.0329885	0.0231737
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	90	1.749373	0.0329885	0.0231737
GO:0001678	cellular glucose homeostasis	122	1.746522	0.0329885	0.0231737
GO:0007212	dopamine receptor signaling pathway	32	1.744495	0.0412551	0.0289807
GO:0009582	detection of abiotic stimulus	103	1.742630	0.0329885	0.0231737
GO:0050773	regulation of dendrite development	137	1.740372	0.0329885	0.0231737
GO:1900006	positive regulation of dendrite development	68	1.738244	0.0398385	0.0279856
GO:0060047	heart contraction	239	1.729889	0.0329885	0.0231737
GO:0050805	negative regulation of synaptic transmission	65	1.727945	0.0361638	0.0254042
GO:1902750	negative regulation of cell cycle G2/M phase transition	89	1.726677	0.0329885	0.0231737
GO:0050772	positive regulation of axonogenesis	68	1.726340	0.0398385	0.0279856
GO:0086065	cell communication involved in cardiac conduction	53	1.721109	0.0451615	0.0317249
GO:0010922	positive regulation of phosphatase activity	29	1.720764	0.0472546	0.0331953
GO:0008089	anterograde axonal transport	42	1.719498	0.0468024	0.0328776
GO:0009308	amine metabolic process	118	1.718747	0.0329885	0.0231737
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	57	1.716750	0.0400578	0.0281397
GO:0051258	protein polymerization	212	1.716319	0.0329885	0.0231737
GO:0002220	innate immune response activating cell surface receptor signaling pathway	95	1.714947	0.0329885	0.0231737
GO:0043624	cellular protein complex disassembly	189	1.712157	0.0329885	0.0231737
GO:0061387	regulation of extent of cell growth	87	1.707442	0.0329885	0.0231737
GO:0032386	regulation of intracellular transport	384	1.702326	0.0329885	0.0231737
GO:0021756	striatum development	19	1.700471	0.0496223	0.0348585
GO:0097485	neuron projection guidance	190	1.697753	0.0329885	0.0231737
GO:0050796	regulation of insulin secretion	147	1.695784	0.0329885	0.0231737
GO:0050850	positive regulation of calcium-mediated signaling	37	1.694157	0.0468024	0.0328776
GO:0000209	protein polyubiquitination	279	1.692666	0.0329885	0.0231737
GO:0010389	regulation of G2/M transition of mitotic cell cycle	175	1.691840	0.0329885	0.0231737
GO:0043270	positive regulation of ion transport	237	1.691439	0.0329885	0.0231737
GO:0001504	neurotransmitter uptake	35	1.688373	0.0468177	0.0328884
GO:0048639	positive regulation of developmental growth	148	1.686601	0.0329885	0.0231737
GO:0098815	modulation of excitatory postsynaptic potential	40	1.686033	0.0414641	0.0291276
GO:0007411	axon guidance	188	1.684894	0.0329885	0.0231737
GO:0009156	ribonucleoside monophosphate biosynthetic process	178	1.684870	0.0329885	0.0231737
GO:0048016	inositol phosphate-mediated signaling	44	1.683970	0.0411452	0.0289035
GO:0000086	G2/M transition of mitotic cell cycle	227	1.679335	0.0329885	0.0231737
GO:0009581	detection of external stimulus	100	1.676362	0.0329885	0.0231737
GO:0090276	regulation of peptide hormone secretion	167	1.673736	0.0329885	0.0231737
GO:1903169	regulation of calcium ion transmembrane transport	131	1.672211	0.0329885	0.0231737
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	93	1.671856	0.0329885	0.0231737
GO:0009152	purine ribonucleotide biosynthetic process	253	1.670815	0.0329885	0.0231737
GO:0046390	ribose phosphate biosynthetic process	270	1.670552	0.0329885	0.0231737
GO:0043523	regulation of neuron apoptotic process	185	1.670277	0.0329885	0.0231737
GO:0032410	negative regulation of transporter activity	64	1.667364	0.0399769	0.0280829
GO:0051962	positive regulation of nervous system development	472	1.664464	0.0329885	0.0231737
GO:0019722	calcium-mediated signaling	163	1.663989	0.0329885	0.0231737
GO:0010959	regulation of metal ion transport	321	1.662330	0.0329885	0.0231737
GO:1905037	autophagosome organization	72	1.662293	0.0398370	0.0279846
GO:0006164	purine nucleotide biosynthetic process	263	1.662232	0.0329885	0.0231737
GO:0019884	antigen processing and presentation of exogenous antigen	164	1.659401	0.0329885	0.0231737
GO:0009127	purine nucleoside monophosphate biosynthetic process	165	1.658463	0.0329885	0.0231737
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	165	1.658463	0.0329885	0.0231737
GO:0086001	cardiac muscle cell action potential	65	1.657872	0.0399769	0.0280829
GO:0009124	nucleoside monophosphate biosynthetic process	185	1.657065	0.0329885	0.0231737
GO:0051402	neuron apoptotic process	211	1.651694	0.0329885	0.0231737
GO:0002478	antigen processing and presentation of exogenous peptide antigen	162	1.650379	0.0329885	0.0231737
GO:1903522	regulation of blood circulation	251	1.650151	0.0329885	0.0231737
GO:1990778	protein localization to cell periphery	260	1.649874	0.0329885	0.0231737
GO:0035304	regulation of protein dephosphorylation	125	1.649792	0.0329885	0.0231737
GO:0003015	heart process	248	1.649419	0.0329885	0.0231737
GO:1904063	negative regulation of cation transmembrane transport	70	1.646627	0.0398385	0.0279856
GO:0097553	calcium ion transmembrane import into cytosol	111	1.646449	0.0329885	0.0231737
GO:0051279	regulation of release of sequestered calcium ion into cytosol	68	1.643922	0.0398385	0.0279856
GO:0009260	ribonucleotide biosynthetic process	266	1.643206	0.0329885	0.0231737
GO:0035303	regulation of dephosphorylation	189	1.642118	0.0329885	0.0231737
GO:0043648	dicarboxylic acid metabolic process	81	1.640228	0.0361638	0.0254042
GO:0009584	detection of visible light	44	1.636438	0.0463643	0.0325699
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	150	1.636214	0.0329885	0.0231737
GO:0006754	ATP biosynthetic process	142	1.635834	0.0329885	0.0231737
GO:0000045	autophagosome assembly	69	1.635262	0.0398385	0.0279856
GO:0032886	regulation of microtubule-based process	195	1.634997	0.0329885	0.0231737
GO:0072347	response to anesthetic	67	1.633743	0.0399769	0.0280829
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	94	1.630325	0.0329885	0.0231737
GO:0072522	purine-containing compound biosynthetic process	273	1.627893	0.0329885	0.0231737
GO:0048013	ephrin receptor signaling pathway	86	1.626647	0.0359985	0.0252881
GO:0034764	positive regulation of transmembrane transport	173	1.625043	0.0329885	0.0231737
GO:0018105	peptidyl-serine phosphorylation	213	1.624816	0.0329885	0.0231737
GO:0044839	cell cycle G2/M phase transition	246	1.622401	0.0329885	0.0231737
GO:0030004	cellular monovalent inorganic cation homeostasis	73	1.618903	0.0393800	0.0276636
GO:0009145	purine nucleoside triphosphate biosynthetic process	151	1.616011	0.0329885	0.0231737
GO:0010921	regulation of phosphatase activity	157	1.613414	0.0329885	0.0231737
GO:0032535	regulation of cellular component size	292	1.613411	0.0329885	0.0231737
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	130	1.611952	0.0351659	0.0247032
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	77	1.608511	0.0438865	0.0308293
GO:0018209	peptidyl-serine modification	232	1.608387	0.0329885	0.0231737
GO:0051592	response to calcium ion	115	1.602920	0.0351670	0.0247040
GO:0006094	gluconeogenesis	74	1.601187	0.0393800	0.0276636
GO:0009749	response to glucose	165	1.600291	0.0329885	0.0231737
GO:0050769	positive regulation of neurogenesis	413	1.599805	0.0329885	0.0231737
GO:1902749	regulation of cell cycle G2/M phase transition	192	1.598032	0.0329885	0.0231737
GO:0009743	response to carbohydrate	196	1.596119	0.0329885	0.0231737
GO:0031333	negative regulation of protein complex assembly	115	1.595746	0.0351670	0.0247040
GO:0034763	negative regulation of transmembrane transport	100	1.591549	0.0422654	0.0296905
GO:0031345	negative regulation of cell projection organization	151	1.586870	0.0329885	0.0231737
GO:0009201	ribonucleoside triphosphate biosynthetic process	155	1.583576	0.0350660	0.0246330
GO:0034766	negative regulation of ion transmembrane transport	81	1.579244	0.0498255	0.0350013
GO:0032271	regulation of protein polymerization	165	1.578958	0.0329885	0.0231737
GO:1905477	positive regulation of protein localization to membrane	111	1.574253	0.0358382	0.0251755
GO:0050848	regulation of calcium-mediated signaling	87	1.571969	0.0496734	0.0348945
GO:0048284	organelle fusion	92	1.571128	0.0393800	0.0276636
GO:0060560	developmental growth involved in morphogenesis	202	1.570183	0.0329885	0.0231737
GO:0051668	localization within membrane	120	1.568688	0.0487162	0.0342220
GO:0033157	regulation of intracellular protein transport	210	1.566313	0.0329885	0.0231737
GO:1901800	positive regulation of proteasomal protein catabolic process	90	1.566068	0.0392689	0.0275855
GO:0043666	regulation of phosphoprotein phosphatase activity	104	1.561188	0.0486938	0.0342063
GO:0009746	response to hexose	170	1.559169	0.0329885	0.0231737
GO:0048193	Golgi vesicle transport	290	1.550247	0.0329885	0.0231737
GO:0072659	protein localization to plasma membrane	223	1.549284	0.0329885	0.0231737
GO:0061136	regulation of proteasomal protein catabolic process	162	1.545539	0.0350660	0.0246330
GO:0046879	hormone secretion	254	1.543492	0.0329885	0.0231737
GO:0019319	hexose biosynthetic process	77	1.542174	0.0497992	0.0349828
GO:0009914	hormone transport	263	1.538192	0.0329885	0.0231737
GO:0048638	regulation of developmental growth	275	1.538192	0.0329885	0.0231737
GO:0070507	regulation of microtubule cytoskeleton organization	167	1.533430	0.0350660	0.0246330
GO:0009142	nucleoside triphosphate biosynthetic process	166	1.532739	0.0378730	0.0266049
GO:0002027	regulation of heart rate	84	1.530637	0.0495946	0.0348391
GO:0010506	regulation of autophagy	301	1.528084	0.0329885	0.0231737
GO:0034284	response to monosaccharide	174	1.525524	0.0329885	0.0231737
GO:0019932	second-messenger-mediated signaling	305	1.519423	0.0329885	0.0231737
GO:0022604	regulation of cell morphogenesis	411	1.515354	0.0329885	0.0231737
GO:0050906	detection of stimulus involved in sensory perception	108	1.514434	0.0424097	0.0297918
GO:0070997	neuron death	311	1.511110	0.0329885	0.0231737
GO:0006914	autophagy	455	1.511034	0.0329885	0.0231737
GO:0061919	process utilizing autophagic mechanism	455	1.511034	0.0329885	0.0231737
GO:0006470	protein dephosphorylation	288	1.510004	0.0329885	0.0231737
GO:0070838	divalent metal ion transport	401	1.509694	0.0329885	0.0231737
GO:1901293	nucleoside phosphate biosynthetic process	343	1.502273	0.0329885	0.0231737
GO:0072511	divalent inorganic cation transport	403	1.501848	0.0329885	0.0231737
GO:0006520	cellular amino acid metabolic process	323	1.501355	0.0329885	0.0231737
GO:0032984	protein-containing complex disassembly	286	1.499978	0.0329885	0.0231737
GO:0010256	endomembrane system organization	344	1.498688	0.0329885	0.0231737
GO:0048002	antigen processing and presentation of peptide antigen	174	1.496180	0.0377405	0.0265118
GO:0009165	nucleotide biosynthetic process	340	1.496154	0.0329885	0.0231737
GO:0006816	calcium ion transport	364	1.493733	0.0329885	0.0231737
GO:0046883	regulation of hormone secretion	215	1.493640	0.0343030	0.0240971
GO:0090150	establishment of protein localization to membrane	267	1.493224	0.0329885	0.0231737
GO:0022411	cellular component disassembly	454	1.491968	0.0329885	0.0231737
GO:0010720	positive regulation of cell development	468	1.491403	0.0329885	0.0231737
GO:0010498	proteasomal protein catabolic process	369	1.490679	0.0329885	0.0231737
GO:1903827	regulation of cellular protein localization	478	1.490491	0.0329885	0.0231737
GO:1901214	regulation of neuron death	279	1.490443	0.0329885	0.0231737
GO:1905475	regulation of protein localization to membrane	167	1.485561	0.0480538	0.0337567
GO:0016311	dephosphorylation	418	1.483413	0.0329885	0.0231737
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	316	1.482798	0.0329885	0.0231737
GO:0070646	protein modification by small protein removal	263	1.468921	0.0370498	0.0260266
GO:0060271	cilium assembly	319	1.462095	0.0329885	0.0231737
GO:0019882	antigen processing and presentation	202	1.449168	0.0414718	0.0291330
GO:0046434	organophosphate catabolic process	211	1.440211	0.0414641	0.0291276
GO:0000226	microtubule cytoskeleton organization	433	1.426885	0.0332928	0.0233874
GO:0044782	cilium organization	328	1.423031	0.0403803	0.0283662
GO:0090066	regulation of anatomical structure size	396	1.416338	0.0329885	0.0231737
GO:0002768	immune response-regulating cell surface receptor signaling pathway	312	1.415533	0.0496734	0.0348945
GO:0051051	negative regulation of transport	412	1.406800	0.0329885	0.0231737
GO:0019941	modification-dependent protein catabolic process	472	1.402441	0.0329885	0.0231737
GO:0006873	cellular ion homeostasis	459	1.398508	0.0329885	0.0231737
GO:0006511	ubiquitin-dependent protein catabolic process	467	1.396923	0.0361638	0.0254042
GO:0030003	cellular cation homeostasis	450	1.380773	0.0332231	0.0233385
GO:0043632	modification-dependent macromolecule catabolic process	479	1.379019	0.0361638	0.0254042
GO:0042176	regulation of protein catabolic process	335	1.377503	0.0498414	0.0350125
GO:0010817	regulation of hormone levels	412	1.354427	0.0490027	0.0344233
GO:0006875	cellular metal ion homeostasis	403	1.351955	0.0488689	0.0343293

Enriched terms for module #73B000 (MTcor = 0.94)

ID	Description	setSize	NES	p.adjust	qvalues
GO:0006335	DNA replication-dependent nucleosome assembly	32	3.281963	0.0163009	0.0113833
GO:0034723	DNA replication-dependent nucleosome organization	32	3.281963	0.0163009	0.0113833
GO:0000183	chromatin silencing at rDNA	39	3.015703	0.0163009	0.0113833
GO:0051290	protein heterotetramerization	51	2.920453	0.0163009	0.0113833
GO:0045653	negative regulation of megakaryocyte differentiation	17	2.823607	0.0163009	0.0113833
GO:0006334	nucleosome assembly	119	2.804989	0.0163009	0.0113833
GO:0045652	regulation of megakaryocyte differentiation	74	2.724017	0.0163009	0.0113833
GO:0030219	megakaryocyte differentiation	90	2.682767	0.0163009	0.0113833
GO:0031497	chromatin assembly	135	2.634938	0.0163009	0.0113833
GO:0034728	nucleosome organization	144	2.572696	0.0163009	0.0113833
GO:0034080	CENP-A containing nucleosome assembly	41	2.502281	0.0163009	0.0113833
GO:0061641	CENP-A containing chromatin organization	41	2.502281	0.0163009	0.0113833
GO:0006333	chromatin assembly or disassembly	159	2.494888	0.0163009	0.0113833
GO:0006323	DNA packaging	168	2.476166	0.0163009	0.0113833
GO:0048514	blood vessel morphogenesis	495	2.414044	0.0163009	0.0113833
GO:0006342	chromatin silencing	76	2.403177	0.0163009	0.0113833
GO:0031055	chromatin remodeling at centromere	45	2.353854	0.0163009	0.0113833
GO:1903707	negative regulation of hemopoiesis	129	2.333940	0.0163009	0.0113833
GO:0003158	endothelium development	106	2.333436	0.0163009	0.0113833
GO:0038111	interleukin-7-mediated signaling pathway	29	2.326228	0.0163009	0.0113833
GO:0060964	regulation of gene silencing by miRNA	110	2.318738	0.0163009	0.0113833
GO:0010718	positive regulation of epithelial to mesenchymal transition	45	2.314219	0.0163009	0.0113833
GO:0043486	histone exchange	50	2.313078	0.0163009	0.0113833
GO:0006336	DNA replication-independent nucleosome assembly	52	2.313018	0.0163009	0.0113833
GO:0034724	DNA replication-independent nucleosome organization	52	2.313018	0.0163009	0.0113833
GO:0060147	regulation of posttranscriptional gene silencing	112	2.300594	0.0163009	0.0113833
GO:0060966	regulation of gene silencing by RNA	112	2.300594	0.0163009	0.0113833
GO:0001525	angiogenesis	418	2.298458	0.0163009	0.0113833
GO:0045814	negative regulation of gene expression, epigenetic	94	2.288462	0.0163009	0.0113833
GO:0065004	protein-DNA complex assembly	191	2.260830	0.0163009	0.0113833
GO:1904018	positive regulation of vasculature development	161	2.253925	0.0163009	0.0113833
GO:0030856	regulation of epithelial cell differentiation	112	2.248593	0.0163009	0.0113833
GO:0001704	formation of primary germ layer	95	2.241676	0.0163009	0.0113833
GO:0007492	endoderm development	60	2.232370	0.0163009	0.0113833
GO:0046637	regulation of alpha-beta T cell differentiation	51	2.231238	0.0163009	0.0113833
GO:0045637	regulation of myeloid cell differentiation	214	2.230233	0.0163009	0.0113833
GO:0045446	endothelial cell differentiation	88	2.218811	0.0163009	0.0113833
GO:0061614	pri-miRNA transcription by RNA polymerase II	43	2.218749	0.0163009	0.0113833
GO:0030198	extracellular matrix organization	286	2.192768	0.0163009	0.0113833
GO:0045766	positive regulation of angiogenesis	143	2.191895	0.0163009	0.0113833
GO:0046632	alpha-beta T cell differentiation	78	2.189461	0.0163009	0.0113833
GO:0046638	positive regulation of alpha-beta T cell differentiation	40	2.185307	0.0163009	0.0113833
GO:1901342	regulation of vasculature development	274	2.184894	0.0163009	0.0113833
GO:0034508	centromere complex assembly	53	2.182849	0.0163009	0.0113833
GO:0046636	negative regulation of alpha-beta T cell activation	31	2.181756	0.0163009	0.0113833
GO:0046631	alpha-beta T cell activation	107	2.163636	0.0163009	0.0113833
GO:0046634	regulation of alpha-beta T cell activation	74	2.156328	0.0163009	0.0113833
GO:0045765	regulation of angiogenesis	246	2.155318	0.0163009	0.0113833
GO:0035195	gene silencing by miRNA	150	2.153835	0.0163009	0.0113833
GO:0045638	negative regulation of myeloid cell differentiation	79	2.147018	0.0163009	0.0113833
GO:0043062	extracellular structure organization	330	2.142770	0.0163009	0.0113833
GO:0001706	endoderm formation	42	2.139188	0.0163009	0.0113833
GO:0050866	negative regulation of cell activation	162	2.138813	0.0163009	0.0113833
GO:0030260	entry into host cell	118	2.134275	0.0163009	0.0113833
GO:0044409	entry into host	118	2.134275	0.0163009	0.0113833
GO:0051806	entry into cell of other organism involved in symbiotic interaction	118	2.134275	0.0163009	0.0113833
GO:0051828	entry into other organism involved in symbiotic interaction	118	2.134275	0.0163009	0.0113833
GO:1904035	regulation of epithelial cell apoptotic process	61	2.128339	0.0163009	0.0113833
GO:0014745	negative regulation of muscle adaptation	11	2.127725	0.0163009	0.0113833
GO:0030855	epithelial cell differentiation	481	2.126033	0.0163009	0.0113833
GO:0002286	T cell activation involved in immune response	70	2.125011	0.0163009	0.0113833
GO:0030099	myeloid cell differentiation	357	2.124192	0.0163009	0.0113833
GO:0045667	regulation of osteoblast differentiation	107	2.124127	0.0163009	0.0113833
GO:0032200	telomere organization	158	2.124006	0.0163009	0.0113833
GO:0061180	mammary gland epithelium development	59	2.120205	0.0163009	0.0113833
GO:0016233	telomere capping	49	2.111809	0.0163009	0.0113833
GO:0071824	protein-DNA complex subunit organization	216	2.107134	0.0163009	0.0113833
GO:0071103	DNA conformation change	253	2.106475	0.0163009	0.0113833
GO:0061138	morphogenesis of a branching epithelium	154	2.106262	0.0163009	0.0113833
GO:0060968	regulation of gene silencing	132	2.104981	0.0163009	0.0113833
GO:0034446	substrate adhesion-dependent cell spreading	82	2.102304	0.0163009	0.0113833
GO:0016441	posttranscriptional gene silencing	155	2.102180	0.0163009	0.0113833
GO:0031047	gene silencing by RNA	174	2.100760	0.0163009	0.0113833
GO:0035194	posttranscriptional gene silencing by RNA	154	2.100144	0.0163009	0.0113833
GO:0042110	T cell activation	376	2.098991	0.0163009	0.0113833
GO:0002064	epithelial cell development	175	2.098650	0.0163009	0.0113833
GO:0035987	endodermal cell differentiation	38	2.098008	0.0163009	0.0113833
GO:0048754	branching morphogenesis of an epithelial tube	126	2.095619	0.0163009	0.0113833
GO:0042307	positive regulation of protein import into nucleus	34	2.095381	0.0163009	0.0113833
GO:0007369	gastrulation	146	2.095188	0.0163009	0.0113833
GO:0002683	negative regulation of immune system process	376	2.094643	0.0163009	0.0113833
GO:0042060	wound healing	458	2.093919	0.0163009	0.0113833
GO:0110110	positive regulation of animal organ morphogenesis	69	2.093698	0.0163009	0.0113833
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	22	2.093155	0.0163009	0.0113833
GO:0051291	protein heterooligomerization	120	2.088588	0.0163009	0.0113833
GO:0033002	muscle cell proliferation	175	2.084705	0.0163009	0.0113833
GO:0030199	collagen fibril organization	40	2.079294	0.0163009	0.0113833
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	13	2.077650	0.0163009	0.0113833
GO:1903708	positive regulation of hemopoiesis	155	2.075687	0.0163009	0.0113833
GO:0035329	hippo signaling	38	2.071621	0.0163009	0.0113833
GO:0032496	response to lipopolysaccharide	248	2.071391	0.0163009	0.0113833
GO:0009617	response to bacterium	413	2.070860	0.0163009	0.0113833
GO:0002237	response to molecule of bacterial origin	260	2.069487	0.0163009	0.0113833
GO:0002819	regulation of adaptive immune response	128	2.068829	0.0163009	0.0113833
GO:0098760	response to interleukin-7	40	2.067516	0.0163009	0.0113833
GO:0098761	cellular response to interleukin-7	40	2.067516	0.0163009	0.0113833
GO:0022612	gland morphogenesis	101	2.064871	0.0163009	0.0113833
GO:0048333	mesodermal cell differentiation	27	2.062396	0.0163009	0.0113833
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	46	2.055948	0.0163009	0.0113833
GO:0002227	innate immune response in mucosa	11	2.052684	0.0163009	0.0113833
GO:0032677	regulation of interleukin-8 production	53	2.051840	0.0163009	0.0113833
GO:0060326	cell chemotaxis	201	2.050613	0.0163009	0.0113833
GO:0003151	outflow tract morphogenesis	70	2.045981	0.0163009	0.0113833
GO:0071216	cellular response to biotic stimulus	178	2.044258	0.0163009	0.0113833
GO:1904036	negative regulation of epithelial cell apoptotic process	30	2.041644	0.0163009	0.0113833
GO:0014741	negative regulation of muscle hypertrophy	25	2.039269	0.0163009	0.0113833
GO:0048368	lateral mesoderm development	13	2.037636	0.0163009	0.0113833
GO:1904894	positive regulation of STAT cascade	61	2.037606	0.0163009	0.0113833
GO:0001570	vasculogenesis	68	2.037259	0.0163009	0.0113833
GO:0072006	nephron development	121	2.037143	0.0163009	0.0113833
GO:0022408	negative regulation of cell-cell adhesion	138	2.034252	0.0163009	0.0113833
GO:0030217	T cell differentiation	193	2.031911	0.0163009	0.0113833
GO:0046718	viral entry into host cell	106	2.031748	0.0163009	0.0113833
GO:0048332	mesoderm morphogenesis	57	2.026901	0.0163009	0.0113833
GO:1902107	positive regulation of leukocyte differentiation	122	2.023687	0.0163009	0.0113833
GO:0002695	negative regulation of leukocyte activation	143	2.023093	0.0163009	0.0113833
GO:0072028	nephron morphogenesis	66	2.021569	0.0163009	0.0113833
GO:0002507	tolerance induction	18	2.019637	0.0163009	0.0113833
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	23	2.017153	0.0163009	0.0113833
GO:0046427	positive regulation of JAK-STAT cascade	59	2.015126	0.0163009	0.0113833
GO:2001236	regulation of extrinsic apoptotic signaling pathway	137	2.014815	0.0163009	0.0113833
GO:0002577	regulation of antigen processing and presentation	15	2.013972	0.0163009	0.0113833
GO:0030278	regulation of ossification	169	2.011543	0.0163009	0.0113833
GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	37	2.011033	0.0163009	0.0113833
GO:1903053	regulation of extracellular matrix organization	36	2.009104	0.0163009	0.0113833
GO:0071222	cellular response to lipopolysaccharide	148	2.007952	0.0163009	0.0113833
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	39	2.005453	0.0256950	0.0179433
GO:0045616	regulation of keratinocyte differentiation	30	2.004612	0.0163009	0.0113833
GO:0090183	regulation of kidney development	46	2.004535	0.0256950	0.0179433
GO:0072073	kidney epithelium development	120	2.002833	0.0163009	0.0113833
GO:0007566	embryo implantation	43	2.002232	0.0258183	0.0180295
GO:0001890	placenta development	131	2.000883	0.0163009	0.0113833
GO:0045621	positive regulation of lymphocyte differentiation	81	2.000118	0.0163009	0.0113833
GO:0050868	negative regulation of T cell activation	89	1.998171	0.0163009	0.0113833
GO:0003181	atrioventricular valve morphogenesis	22	1.997860	0.0163009	0.0113833
GO:0001763	morphogenesis of a branching structure	167	1.997080	0.0163009	0.0113833
GO:0051250	negative regulation of lymphocyte activation	117	1.996758	0.0163009	0.0113833
GO:2000482	regulation of interleukin-8 secretion	20	1.994918	0.0163009	0.0113833
GO:0060479	lung cell differentiation	15	1.990732	0.0256950	0.0179433
GO:0071219	cellular response to molecule of bacterial origin	155	1.990147	0.0163009	0.0113833
GO:2000179	positive regulation of neural precursor cell proliferation	44	1.989036	0.0256950	0.0179433
GO:1904019	epithelial cell apoptotic process	81	1.987989	0.0163009	0.0113833
GO:0002285	lymphocyte activation involved in immune response	128	1.986501	0.0163009	0.0113833
GO:0032060	bleb assembly	11	1.985604	0.0163009	0.0113833
GO:0045669	positive regulation of osteoblast differentiation	61	1.985265	0.0163009	0.0113833
GO:0061005	cell differentiation involved in kidney development	48	1.984123	0.0257133	0.0179562
GO:1901626	regulation of postsynaptic membrane organization	14	1.982813	0.0163009	0.0113833
GO:2000826	regulation of heart morphogenesis	32	1.982671	0.0163009	0.0113833
GO:0042129	regulation of T cell proliferation	123	1.980702	0.0163009	0.0113833
GO:2000351	regulation of endothelial cell apoptotic process	36	1.978509	0.0163009	0.0113833
GO:0048708	astrocyte differentiation	71	1.978094	0.0163009	0.0113833
GO:0030206	chondroitin sulfate biosynthetic process	25	1.976975	0.0163009	0.0113833
GO:0002821	positive regulation of adaptive immune response	78	1.976761	0.0163009	0.0113833
GO:0009595	detection of biotic stimulus	17	1.975224	0.0163009	0.0113833
GO:0001655	urogenital system development	286	1.975188	0.0163009	0.0113833
GO:0045604	regulation of epidermal cell differentiation	45	1.974814	0.0256950	0.0179433
GO:0002287	alpha-beta T cell activation involved in immune response	47	1.974340	0.0256950	0.0179433
GO:0002293	alpha-beta T cell differentiation involved in immune response	47	1.974340	0.0256950	0.0179433
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	47	1.974340	0.0256950	0.0179433
GO:0045582	positive regulation of T cell differentiation	71	1.974294	0.0163009	0.0113833
GO:0035710	CD4-positive, alpha-beta T cell activation	71	1.973952	0.0163009	0.0113833
GO:0046635	positive regulation of alpha-beta T cell activation	51	1.971458	0.0163009	0.0113833
GO:0046639	negative regulation of alpha-beta T cell differentiation	21	1.971344	0.0163009	0.0113833
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	73	1.971195	0.0163009	0.0113833
GO:0072207	metanephric epithelium development	23	1.970801	0.0163009	0.0113833
GO:0003183	mitral valve morphogenesis	10	1.970504	0.0163009	0.0113833
GO:2000147	positive regulation of cell motility	442	1.969086	0.0163009	0.0113833
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	197	1.966630	0.0163009	0.0113833
GO:0030335	positive regulation of cell migration	427	1.966054	0.0163009	0.0113833
GO:0072132	mesenchyme morphogenesis	47	1.964821	0.0256950	0.0179433
GO:0072001	renal system development	260	1.963360	0.0163009	0.0113833
GO:0072009	nephron epithelium development	90	1.963098	0.0163009	0.0113833
GO:0001822	kidney development	245	1.962898	0.0163009	0.0113833
GO:0060411	cardiac septum morphogenesis	67	1.961579	0.0163009	0.0113833
GO:0030858	positive regulation of epithelial cell differentiation	49	1.960627	0.0256950	0.0179433
GO:0001707	mesoderm formation	55	1.960582	0.0163009	0.0113833
GO:0032637	interleukin-8 production	58	1.959157	0.0163009	0.0113833
GO:0097150	neuronal stem cell population maintenance	22	1.958891	0.0163009	0.0113833
GO:0060561	apoptotic process involved in morphogenesis	21	1.958723	0.0163009	0.0113833
GO:0061326	renal tubule development	79	1.955483	0.0163009	0.0113833
GO:0003007	heart morphogenesis	213	1.954472	0.0163009	0.0113833
GO:0002250	adaptive immune response	290	1.951776	0.0163009	0.0113833
GO:2000811	negative regulation of anoikis	15	1.951105	0.0256950	0.0179433
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	114	1.948942	0.0163009	0.0113833
GO:0072080	nephron tubule development	77	1.948245	0.0163009	0.0113833
GO:0072088	nephron epithelium morphogenesis	64	1.947935	0.0163009	0.0113833
GO:0042742	defense response to bacterium	120	1.946931	0.0163009	0.0113833
GO:0042093	T-helper cell differentiation	46	1.945784	0.0256950	0.0179433
GO:0003382	epithelial cell morphogenesis	25	1.944556	0.0163009	0.0113833
GO:0002088	lens development in camera-type eye	58	1.943813	0.0163009	0.0113833
GO:2000036	regulation of stem cell population maintenance	25	1.940979	0.0163009	0.0113833
GO:0006968	cellular defense response	40	1.940089	0.0256950	0.0179433
GO:1905332	positive regulation of morphogenesis of an epithelium	31	1.939865	0.0163009	0.0113833
GO:0003171	atrioventricular valve development	23	1.939460	0.0163009	0.0113833
GO:0010463	mesenchymal cell proliferation	41	1.938546	0.0256950	0.0179433
GO:0048844	artery morphogenesis	58	1.938415	0.0163009	0.0113833
GO:0043297	apical junction assembly	55	1.938197	0.0163009	0.0113833
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	23	1.936605	0.0163009	0.0113833
GO:0001656	metanephros development	74	1.936547	0.0163009	0.0113833
GO:0072243	metanephric nephron epithelium development	20	1.934631	0.0163009	0.0113833
GO:1904591	positive regulation of protein import	36	1.934484	0.0163009	0.0113833
GO:0006509	membrane protein ectodomain proteolysis	37	1.933582	0.0163009	0.0113833
GO:0002292	T cell differentiation involved in immune response	49	1.933045	0.0256950	0.0179433
GO:0035635	entry of bacterium into host cell	14	1.931106	0.0256950	0.0179433
GO:0050900	leukocyte migration	335	1.929425	0.0163009	0.0113833
GO:0001885	endothelial cell development	53	1.928683	0.0163009	0.0113833
GO:0072170	metanephric tubule development	22	1.927899	0.0163009	0.0113833
GO:0043367	CD4-positive, alpha-beta T cell differentiation	58	1.927700	0.0163009	0.0113833
GO:0050777	negative regulation of immune response	116	1.926393	0.0163009	0.0113833
GO:0050673	epithelial cell proliferation	326	1.925842	0.0163009	0.0113833
GO:0072577	endothelial cell apoptotic process	42	1.925825	0.0256950	0.0179433
GO:0001503	ossification	339	1.925490	0.0163009	0.0113833
GO:0060993	kidney morphogenesis	81	1.922369	0.0163009	0.0113833
GO:0051568	histone H3-K4 methylation	46	1.921827	0.0256950	0.0179433
GO:0002385	mucosal immune response	14	1.920873	0.0325638	0.0227400
GO:0001892	embryonic placenta development	78	1.920229	0.0163009	0.0113833
GO:0050830	defense response to Gram-positive bacterium	45	1.919976	0.0256950	0.0179433
GO:0000768	syncytium formation by plasma membrane fusion	41	1.919721	0.0256950	0.0179433
GO:0140253	cell-cell fusion	41	1.919721	0.0256950	0.0179433
GO:1902807	negative regulation of cell cycle G1/S phase transition	102	1.918019	0.0163009	0.0113833
GO:0072078	nephron tubule morphogenesis	62	1.918014	0.0163009	0.0113833
GO:0042102	positive regulation of T cell proliferation	69	1.917452	0.0163009	0.0113833
GO:0042267	natural killer cell mediated cytotoxicity	43	1.916163	0.0327718	0.0228853
GO:0010759	positive regulation of macrophage chemotaxis	14	1.915875	0.0325638	0.0227400
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	100	1.915439	0.0163009	0.0113833
GO:0002825	regulation of T-helper 1 type immune response	18	1.915277	0.0163009	0.0113833
GO:0051272	positive regulation of cellular component movement	455	1.914921	0.0163009	0.0113833
GO:1903038	negative regulation of leukocyte cell-cell adhesion	98	1.914414	0.0163009	0.0113833
GO:0036119	response to platelet-derived growth factor	21	1.910974	0.0163009	0.0113833
GO:1903706	regulation of hemopoiesis	409	1.910713	0.0163009	0.0113833
GO:0046697	decidualization	22	1.909212	0.0163009	0.0113833
GO:0045655	regulation of monocyte differentiation	16	1.908668	0.0256950	0.0179433
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	37	1.907452	0.0163009	0.0113833
GO:0061053	somite development	65	1.907433	0.0163009	0.0113833
GO:0042269	regulation of natural killer cell mediated cytotoxicity	29	1.907006	0.0163009	0.0113833
GO:0003170	heart valve development	54	1.906001	0.0163009	0.0113833
GO:0010614	negative regulation of cardiac muscle hypertrophy	23	1.905537	0.0163009	0.0113833
GO:1905523	positive regulation of macrophage migration	19	1.904808	0.0256950	0.0179433
GO:0042098	T cell proliferation	151	1.903371	0.0163009	0.0113833
GO:0048661	positive regulation of smooth muscle cell proliferation	81	1.902375	0.0163009	0.0113833
GO:0030323	respiratory tube development	156	1.902275	0.0163009	0.0113833
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	24	1.900477	0.0163009	0.0113833
GO:0072171	mesonephric tubule morphogenesis	57	1.900140	0.0163009	0.0113833
GO:0007498	mesoderm development	100	1.899509	0.0163009	0.0113833
GO:0030324	lung development	152	1.898808	0.0163009	0.0113833
GO:0031589	cell-substrate adhesion	295	1.896323	0.0163009	0.0113833
GO:0060487	lung epithelial cell differentiation	14	1.895789	0.0325638	0.0227400
GO:0001773	myeloid dendritic cell activation	21	1.894269	0.0163009	0.0113833
GO:0010631	epithelial cell migration	256	1.893528	0.0163009	0.0113833
GO:0002827	positive regulation of T-helper 1 type immune response	12	1.893490	0.0163009	0.0113833
GO:0014015	positive regulation of gliogenesis	69	1.892174	0.0163009	0.0113833
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	87	1.891388	0.0163009	0.0113833
GO:0043044	ATP-dependent chromatin remodeling	72	1.891105	0.0163009	0.0113833
GO:1901213	regulation of transcription from RNA polymerase II promoter involved in heart development	12	1.890390	0.0163009	0.0113833
GO:0002715	regulation of natural killer cell mediated immunity	31	1.887702	0.0163009	0.0113833
GO:0060135	maternal process involved in female pregnancy	56	1.887460	0.0163009	0.0113833
GO:0045601	regulation of endothelial cell differentiation	26	1.887459	0.0163009	0.0113833
GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	27	1.886344	0.0163009	0.0113833
GO:0090594	inflammatory response to wounding	12	1.885613	0.0163009	0.0113833
GO:0001667	ameboidal-type cell migration	333	1.885574	0.0163009	0.0113833
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	28	1.885434	0.0163009	0.0113833
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	204	1.884494	0.0163009	0.0113833
GO:0016458	gene silencing	227	1.882284	0.0163009	0.0113833
GO:0007249	I-kappaB kinase/NF-kappaB signaling	231	1.882138	0.0163009	0.0113833
GO:0014855	striated muscle cell proliferation	58	1.878940	0.0163009	0.0113833
GO:0045581	negative regulation of T cell differentiation	38	1.877032	0.0256950	0.0179433
GO:0032757	positive regulation of interleukin-8 production	36	1.876516	0.0256950	0.0179433
GO:0090132	epithelium migration	257	1.875151	0.0163009	0.0113833
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	27	1.874601	0.0163009	0.0113833
GO:0061333	renal tubule morphogenesis	66	1.874248	0.0163009	0.0113833
GO:0002040	sprouting angiogenesis	100	1.872913	0.0163009	0.0113833
GO:0060675	ureteric bud morphogenesis	56	1.871069	0.0163009	0.0113833
GO:0043542	endothelial cell migration	187	1.869551	0.0163009	0.0113833
GO:0001658	branching involved in ureteric bud morphogenesis	51	1.869461	0.0259198	0.0181004
GO:2000737	negative regulation of stem cell differentiation	19	1.869447	0.0256950	0.0179433
GO:0040017	positive regulation of locomotion	470	1.868969	0.0163009	0.0113833
GO:0030098	lymphocyte differentiation	272	1.868650	0.0163009	0.0113833
GO:0001837	epithelial to mesenchymal transition	121	1.867779	0.0163009	0.0113833
GO:0071674	mononuclear cell migration	54	1.867547	0.0163009	0.0113833
GO:0036120	cellular response to platelet-derived growth factor stimulus	20	1.866624	0.0256950	0.0179433
GO:0070663	regulation of leukocyte proliferation	177	1.866292	0.0163009	0.0113833
GO:0002697	regulation of immune effector process	310	1.864815	0.0163009	0.0113833
GO:0007159	leukocyte cell-cell adhesion	272	1.864264	0.0163009	0.0113833
GO:0001756	somitogenesis	49	1.864114	0.0256950	0.0179433
GO:0006949	syncytium formation	42	1.863773	0.0256950	0.0179433
GO:0007596	blood coagulation	276	1.863759	0.0163009	0.0113833
GO:0050817	coagulation	278	1.862314	0.0163009	0.0113833
GO:0060541	respiratory system development	174	1.862072	0.0163009	0.0113833
GO:0072234	metanephric nephron tubule development	19	1.861117	0.0256950	0.0179433
GO:0090130	tissue migration	262	1.859746	0.0163009	0.0113833
GO:0007221	positive regulation of transcription of Notch receptor target	17	1.859224	0.0325638	0.0227400
GO:1990868	response to chemokine	47	1.859103	0.0256950	0.0179433
GO:1990869	cellular response to chemokine	47	1.859103	0.0256950	0.0179433
GO:0048762	mesenchymal cell differentiation	171	1.858978	0.0163009	0.0113833
GO:0001657	ureteric bud development	87	1.858747	0.0163009	0.0113833
GO:0002714	positive regulation of B cell mediated immunity	28	1.857075	0.0163009	0.0113833
GO:0002891	positive regulation of immunoglobulin mediated immune response	28	1.857075	0.0163009	0.0113833
GO:0003174	mitral valve development	11	1.855191	0.0256950	0.0179433
GO:0002228	natural killer cell mediated immunity	47	1.854758	0.0256950	0.0179433
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	10	1.853873	0.0163009	0.0113833
GO:0032611	interleukin-1 beta production	71	1.853723	0.0163009	0.0113833
GO:0046640	regulation of alpha-beta T cell proliferation	23	1.852490	0.0163009	0.0113833
GO:0072163	mesonephric epithelium development	88	1.851483	0.0163009	0.0113833
GO:0072164	mesonephric tubule development	88	1.851483	0.0163009	0.0113833
GO:0032963	collagen metabolic process	79	1.851348	0.0163009	0.0113833
GO:0002521	leukocyte differentiation	407	1.849519	0.0163009	0.0113833
GO:0050678	regulation of epithelial cell proliferation	276	1.847584	0.0163009	0.0113833
GO:0002920	regulation of humoral immune response	46	1.846352	0.0256950	0.0179433
GO:0010594	regulation of endothelial cell migration	145	1.846086	0.0163009	0.0113833
GO:0045778	positive regulation of ossification	85	1.845822	0.0163009	0.0113833
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	59	1.845744	0.0163009	0.0113833
GO:0061045	negative regulation of wound healing	58	1.845279	0.0163009	0.0113833
GO:1903670	regulation of sprouting angiogenesis	63	1.844496	0.0163009	0.0113833
GO:0060713	labyrinthine layer morphogenesis	18	1.844154	0.0468647	0.0327267
GO:0032944	regulation of mononuclear cell proliferation	169	1.843834	0.0163009	0.0113833
GO:0061041	regulation of wound healing	113	1.843206	0.0163009	0.0113833
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	24	1.842983	0.0256950	0.0179433
GO:0019915	lipid storage	57	1.841538	0.0163009	0.0113833
GO:0002703	regulation of leukocyte mediated immunity	155	1.840757	0.0163009	0.0113833
GO:0060317	cardiac epithelial to mesenchymal transition	32	1.840155	0.0163009	0.0113833
GO:0033687	osteoblast proliferation	22	1.840090	0.0163009	0.0113833
GO:0055092	sterol homeostasis	59	1.839947	0.0163009	0.0113833
GO:0061383	trabecula morphogenesis	44	1.839812	0.0325638	0.0227400
GO:1901890	positive regulation of cell junction assembly	31	1.839795	0.0163009	0.0113833
GO:0060485	mesenchyme development	210	1.839608	0.0163009	0.0113833
GO:0048660	regulation of smooth muscle cell proliferation	125	1.837426	0.0163009	0.0113833
GO:0033631	cell-cell adhesion mediated by integrin	14	1.837265	0.0325638	0.0227400
GO:0046633	alpha-beta T cell proliferation	26	1.836904	0.0163009	0.0113833
GO:0007565	female pregnancy	159	1.835430	0.0163009	0.0113833
GO:0040029	regulation of gene expression, epigenetic	283	1.833592	0.0163009	0.0113833
GO:0098581	detection of external biotic stimulus	13	1.833551	0.0399030	0.0278651
GO:0060562	epithelial tube morphogenesis	274	1.833518	0.0163009	0.0113833
GO:0050670	regulation of lymphocyte proliferation	168	1.832897	0.0163009	0.0113833
GO:0060009	Sertoli cell development	14	1.832823	0.0325638	0.0227400
GO:0001710	mesodermal cell fate commitment	15	1.832544	0.0397381	0.0277500
GO:0001823	mesonephros development	90	1.832539	0.0163009	0.0113833
GO:0060425	lung morphogenesis	45	1.832494	0.0325638	0.0227400
GO:0030224	monocyte differentiation	31	1.832143	0.0163009	0.0113833
GO:1903131	mononuclear cell differentiation	31	1.832143	0.0163009	0.0113833
GO:1903037	regulation of leukocyte cell-cell adhesion	244	1.830181	0.0163009	0.0113833
GO:0002532	production of molecular mediator involved in inflammatory response	56	1.829235	0.0163009	0.0113833
GO:0048260	positive regulation of receptor-mediated endocytosis	43	1.825883	0.0327718	0.0228853
GO:0072111	cell proliferation involved in kidney development	16	1.825036	0.0467758	0.0326645
GO:0050679	positive regulation of epithelial cell proliferation	159	1.824577	0.0163009	0.0113833
GO:0001649	osteoblast differentiation	193	1.823856	0.0163009	0.0113833
GO:0050702	interleukin-1 beta secretion	42	1.823766	0.0325638	0.0227400
GO:0010811	positive regulation of cell-substrate adhesion	98	1.823616	0.0163009	0.0113833
GO:0002706	regulation of lymphocyte mediated immunity	109	1.823408	0.0163009	0.0113833
GO:0046641	positive regulation of alpha-beta T cell proliferation	14	1.823202	0.0325638	0.0227400
GO:0045620	negative regulation of lymphocyte differentiation	44	1.822794	0.0325638	0.0227400
GO:0034121	regulation of toll-like receptor signaling pathway	59	1.821114	0.0163009	0.0113833
GO:0007599	hemostasis	280	1.819826	0.0163009	0.0113833
GO:0050863	regulation of T cell activation	259	1.818125	0.0163009	0.0113833
GO:0003179	heart valve morphogenesis	46	1.818028	0.0256950	0.0179433
GO:0007507	heart development	479	1.817890	0.0163009	0.0113833
GO:0022407	regulation of cell-cell adhesion	321	1.816402	0.0163009	0.0113833
GO:0007179	transforming growth factor beta receptor signaling pathway	162	1.816087	0.0163009	0.0113833
GO:0048659	smooth muscle cell proliferation	127	1.815300	0.0163009	0.0113833
GO:0060669	embryonic placenta morphogenesis	23	1.814344	0.0256950	0.0179433
GO:0060008	Sertoli cell differentiation	18	1.813795	0.0468647	0.0327267
GO:0045785	positive regulation of cell adhesion	334	1.813704	0.0163009	0.0113833
GO:0002449	lymphocyte mediated immunity	187	1.813407	0.0163009	0.0113833
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	12	1.813050	0.0327126	0.0228439
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	28	1.812344	0.0256950	0.0179433
GO:0003206	cardiac chamber morphogenesis	108	1.811903	0.0163009	0.0113833
GO:1903039	positive regulation of leukocyte cell-cell adhesion	178	1.811751	0.0163009	0.0113833
GO:0034329	cell junction assembly	201	1.811580	0.0163009	0.0113833
GO:0003215	cardiac right ventricle morphogenesis	11	1.811505	0.0325638	0.0227400
GO:0043484	regulation of RNA splicing	106	1.809896	0.0163009	0.0113833
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	44	1.808973	0.0325638	0.0227400
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	32	1.808237	0.0163009	0.0113833
GO:0002712	regulation of B cell mediated immunity	40	1.808092	0.0325638	0.0227400
GO:0002889	regulation of immunoglobulin mediated immune response	40	1.808092	0.0325638	0.0227400
GO:0002221	pattern recognition receptor signaling pathway	168	1.807998	0.0163009	0.0113833
GO:1903671	negative regulation of sprouting angiogenesis	23	1.807662	0.0256950	0.0179433
GO:1905953	negative regulation of lipid localization	33	1.804654	0.0163009	0.0113833
GO:2000050	regulation of non-canonical Wnt signaling pathway	22	1.804380	0.0325638	0.0227400
GO:0001893	maternal placenta development	33	1.803910	0.0163009	0.0113833
GO:0032612	interleukin-1 production	80	1.803802	0.0163009	0.0113833
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	24	1.802113	0.0256950	0.0179433
GO:0002548	monocyte chemotaxis	33	1.801957	0.0163009	0.0113833
GO:0033619	membrane protein proteolysis	52	1.800198	0.0259198	0.0181004
GO:0060142	regulation of syncytium formation by plasma membrane fusion	21	1.799761	0.0256950	0.0179433
GO:0085029	extracellular matrix assembly	25	1.799709	0.0325638	0.0227400
GO:0048644	muscle organ morphogenesis	62	1.799307	0.0163009	0.0113833
GO:0043535	regulation of blood vessel endothelial cell migration	83	1.798916	0.0163009	0.0113833
GO:0032675	regulation of interleukin-6 production	106	1.798374	0.0163009	0.0113833
GO:0010632	regulation of epithelial cell migration	201	1.797881	0.0163009	0.0113833
GO:0019731	antibacterial humoral response	20	1.796163	0.0397381	0.0277500
GO:1900016	negative regulation of cytokine production involved in inflammatory response	15	1.795767	0.0397381	0.0277500
GO:0002251	organ or tissue specific immune response	17	1.794706	0.0467808	0.0326681
GO:2000177	regulation of neural precursor cell proliferation	78	1.794394	0.0163009	0.0113833
GO:1901343	negative regulation of vasculature development	100	1.794285	0.0163009	0.0113833
GO:0006023	aminoglycan biosynthetic process	103	1.792814	0.0163009	0.0113833
GO:0060412	ventricular septum morphogenesis	41	1.792802	0.0397381	0.0277500
GO:0006352	DNA-templated transcription, initiation	215	1.792801	0.0163009	0.0113833
GO:1903909	regulation of receptor clustering	12	1.791603	0.0327126	0.0228439
GO:0071560	cellular response to transforming growth factor beta stimulus	207	1.790781	0.0163009	0.0113833
GO:0051262	protein tetramerization	157	1.790668	0.0163009	0.0113833
GO:1902337	regulation of apoptotic process involved in morphogenesis	11	1.790413	0.0464540	0.0324398
GO:1904748	regulation of apoptotic process involved in development	11	1.790413	0.0464540	0.0324398
GO:0050870	positive regulation of T cell activation	165	1.790322	0.0163009	0.0113833
GO:0042632	cholesterol homeostasis	58	1.789960	0.0259198	0.0181004
GO:0019724	B cell mediated immunity	88	1.789203	0.0163009	0.0113833
GO:0006024	glycosaminoglycan biosynthetic process	102	1.788838	0.0163009	0.0113833
GO:0048339	paraxial mesoderm development	15	1.788537	0.0397381	0.0277500
GO:1902105	regulation of leukocyte differentiation	223	1.788017	0.0163009	0.0113833
GO:0030879	mammary gland development	118	1.787845	0.0163009	0.0113833
GO:0003272	endocardial cushion formation	23	1.785965	0.0325638	0.0227400
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	16	1.785645	0.0467758	0.0326645
GO:0045639	positive regulation of myeloid cell differentiation	71	1.784747	0.0163009	0.0113833
GO:0071559	response to transforming growth factor beta	213	1.781451	0.0163009	0.0113833
GO:0035909	aorta morphogenesis	28	1.781122	0.0325638	0.0227400
GO:0036499	PERK-mediated unfolded protein response	20	1.780651	0.0397381	0.0277500
GO:0048732	gland development	355	1.779743	0.0163009	0.0113833
GO:0016064	immunoglobulin mediated immune response	86	1.779681	0.0163009	0.0113833
GO:0034505	tooth mineralization	16	1.778963	0.0467758	0.0326645
GO:0046209	nitric oxide metabolic process	66	1.778213	0.0163009	0.0113833
GO:0045685	regulation of glial cell differentiation	71	1.777066	0.0163009	0.0113833
GO:0010742	macrophage derived foam cell differentiation	28	1.776461	0.0325638	0.0227400
GO:0090077	foam cell differentiation	28	1.776461	0.0325638	0.0227400
GO:2000352	negative regulation of endothelial cell apoptotic process	20	1.775820	0.0397381	0.0277500
GO:0060977	coronary vasculature morphogenesis	14	1.774879	0.0399030	0.0278651
GO:0010470	regulation of gastrulation	32	1.773164	0.0163009	0.0113833
GO:0030166	proteoglycan biosynthetic process	52	1.772613	0.0336977	0.0235318
GO:0001954	positive regulation of cell-matrix adhesion	44	1.772239	0.0325638	0.0227400
GO:0045622	regulation of T-helper cell differentiation	27	1.771855	0.0256950	0.0179433
GO:0001654	eye development	303	1.771519	0.0163009	0.0113833
GO:0050878	regulation of body fluid levels	413	1.770007	0.0163009	0.0113833
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	12	1.768370	0.0399030	0.0278651
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	18	1.768002	0.0468647	0.0327267
GO:0032835	glomerulus development	52	1.767365	0.0336977	0.0235318
GO:0051249	regulation of lymphocyte activation	345	1.764462	0.0163009	0.0113833
GO:0072202	cell differentiation involved in metanephros development	23	1.764297	0.0325638	0.0227400
GO:0043534	blood vessel endothelial cell migration	107	1.763994	0.0163009	0.0113833
GO:0010888	negative regulation of lipid storage	15	1.762937	0.0467808	0.0326681
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	48	1.762073	0.0399030	0.0278651
GO:0003229	ventricular cardiac muscle tissue development	45	1.761894	0.0399030	0.0278651
GO:0042306	regulation of protein import into nucleus	51	1.761182	0.0404520	0.0282485
GO:0050865	regulation of cell activation	453	1.761097	0.0163009	0.0113833
GO:0150063	visual system development	307	1.761070	0.0163009	0.0113833
GO:0002708	positive regulation of lymphocyte mediated immunity	72	1.760566	0.0163009	0.0113833
GO:0007160	cell-matrix adhesion	192	1.760495	0.0163009	0.0113833
GO:0050921	positive regulation of chemotaxis	114	1.760388	0.0163009	0.0113833
GO:0042304	regulation of fatty acid biosynthetic process	36	1.759831	0.0256950	0.0179433
GO:0045682	regulation of epidermis development	63	1.759361	0.0163009	0.0113833
GO:0045619	regulation of lymphocyte differentiation	139	1.758581	0.0163009	0.0113833
GO:0010575	positive regulation of vascular endothelial growth factor production	24	1.758009	0.0397381	0.0277500
GO:0060428	lung epithelium development	28	1.757250	0.0325638	0.0227400
GO:0007162	negative regulation of cell adhesion	223	1.756730	0.0163009	0.0113833
GO:0051251	positive regulation of lymphocyte activation	218	1.756096	0.0163009	0.0113833
GO:0032964	collagen biosynthetic process	40	1.755332	0.0325638	0.0227400
GO:0043010	camera-type eye development	263	1.755043	0.0163009	0.0113833
GO:0010831	positive regulation of myotube differentiation	23	1.754484	0.0325638	0.0227400
GO:0035850	epithelial cell differentiation involved in kidney development	39	1.754133	0.0325638	0.0227400
GO:0043277	apoptotic cell clearance	35	1.751872	0.0325638	0.0227400
GO:0061448	connective tissue development	202	1.751458	0.0163009	0.0113833
GO:0003281	ventricular septum development	68	1.751388	0.0259198	0.0181004
GO:0003279	cardiac septum development	101	1.750747	0.0163009	0.0113833
GO:2001057	reactive nitrogen species metabolic process	69	1.749285	0.0163009	0.0113833
GO:0042089	cytokine biosynthetic process	89	1.748636	0.0163009	0.0113833
GO:0048880	sensory system development	308	1.748489	0.0163009	0.0113833
GO:0051147	regulation of muscle cell differentiation	138	1.748004	0.0163009	0.0113833
GO:0044706	multi-multicellular organism process	186	1.747020	0.0163009	0.0113833
GO:0042692	muscle cell differentiation	289	1.746236	0.0163009	0.0113833
GO:0043536	positive regulation of blood vessel endothelial cell migration	53	1.745795	0.0404520	0.0282485
GO:0050728	negative regulation of inflammatory response	110	1.745551	0.0163009	0.0113833
GO:0045687	positive regulation of glial cell differentiation	45	1.745505	0.0399030	0.0278651
GO:0044319	wound healing, spreading of cells	28	1.745239	0.0325638	0.0227400
GO:0090505	epiboly involved in wound healing	28	1.745239	0.0325638	0.0227400
GO:0001825	blastocyst formation	32	1.745151	0.0163009	0.0113833
GO:1902106	negative regulation of leukocyte differentiation	84	1.745144	0.0163009	0.0113833
GO:0051894	positive regulation of focal adhesion assembly	23	1.744498	0.0395251	0.0276012
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	14	1.744128	0.0468647	0.0327267
GO:0042789	mRNA transcription by RNA polymerase II	16	1.743970	0.0467758	0.0326645
GO:0018022	peptidyl-lysine methylation	112	1.743645	0.0163009	0.0113833
GO:0060333	interferon-gamma-mediated signaling pathway	83	1.743626	0.0163009	0.0113833
GO:0048608	reproductive structure development	354	1.742536	0.0163009	0.0113833
GO:0018126	protein hydroxylation	22	1.741543	0.0397381	0.0277500
GO:0061311	cell surface receptor signaling pathway involved in heart development	27	1.741464	0.0325926	0.0227601
GO:0072574	hepatocyte proliferation	16	1.741105	0.0467758	0.0326645
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	16	1.741105	0.0467758	0.0326645
GO:0050864	regulation of B cell activation	97	1.740461	0.0259198	0.0181004
GO:0010595	positive regulation of endothelial cell migration	95	1.740267	0.0259198	0.0181004
GO:2000379	positive regulation of reactive oxygen species metabolic process	83	1.740147	0.0163009	0.0113833
GO:0034330	cell junction organization	259	1.739877	0.0163009	0.0113833
GO:0033688	regulation of osteoblast proliferation	21	1.738387	0.0399030	0.0278651
GO:0034968	histone lysine methylation	100	1.738066	0.0163009	0.0113833
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	32	1.737712	0.0163009	0.0113833
GO:1903035	negative regulation of response to wounding	71	1.737445	0.0163009	0.0113833
GO:0019058	viral life cycle	292	1.737349	0.0163009	0.0113833
GO:0071604	transforming growth factor beta production	32	1.737176	0.0163009	0.0113833
GO:0070935	3’-UTR-mediated mRNA stabilization	14	1.736828	0.0468647	0.0327267
GO:0003203	endocardial cushion morphogenesis	32	1.736728	0.0163009	0.0113833
GO:2000778	positive regulation of interleukin-6 secretion	23	1.736182	0.0465001	0.0324720
GO:0010717	regulation of epithelial to mesenchymal transition	77	1.735835	0.0163009	0.0113833
GO:0070661	leukocyte proliferation	227	1.735540	0.0163009	0.0113833
GO:0045580	regulation of T cell differentiation	117	1.733667	0.0163009	0.0113833
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	35	1.733401	0.0325638	0.0227400
GO:0032103	positive regulation of response to external stimulus	251	1.733346	0.0163009	0.0113833
GO:0048598	embryonic morphogenesis	462	1.732915	0.0163009	0.0113833
GO:1903034	regulation of response to wounding	140	1.731253	0.0163009	0.0113833
GO:0001569	branching involved in blood vessel morphogenesis	26	1.730460	0.0399030	0.0278651
GO:0035313	wound healing, spreading of epidermal cells	14	1.730444	0.0468647	0.0327267
GO:0003231	cardiac ventricle development	112	1.730000	0.0163009	0.0113833
GO:0002262	myeloid cell homeostasis	130	1.728983	0.0163009	0.0113833
GO:0002694	regulation of leukocyte activation	420	1.728955	0.0163009	0.0113833
GO:0045598	regulation of fat cell differentiation	108	1.728722	0.0163009	0.0113833
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	159	1.728286	0.0163009	0.0113833
GO:0035886	vascular smooth muscle cell differentiation	24	1.727656	0.0397381	0.0277500
GO:1901222	regulation of NIK/NF-kappaB signaling	93	1.727335	0.0259198	0.0181004
GO:0016577	histone demethylation	24	1.726554	0.0397381	0.0277500
GO:0034341	response to interferon-gamma	159	1.726475	0.0163009	0.0113833
GO:0060563	neuroepithelial cell differentiation	45	1.725731	0.0468647	0.0327267
GO:0014031	mesenchymal cell development	56	1.725517	0.0399424	0.0278926
GO:0014013	regulation of gliogenesis	111	1.725452	0.0163009	0.0113833
GO:0070664	negative regulation of leukocyte proliferation	63	1.723531	0.0163009	0.0113833
GO:0035767	endothelial cell chemotaxis	24	1.723053	0.0397381	0.0277500
GO:0060840	artery development	81	1.722713	0.0163009	0.0113833
GO:0008360	regulation of cell shape	118	1.722624	0.0163009	0.0113833
GO:0042107	cytokine metabolic process	90	1.722333	0.0163009	0.0113833
GO:0007044	cell-substrate junction assembly	93	1.722018	0.0259198	0.0181004
GO:0032922	circadian regulation of gene expression	57	1.722014	0.0399030	0.0278651
GO:0010634	positive regulation of epithelial cell migration	134	1.721574	0.0163009	0.0113833
GO:0070665	positive regulation of leukocyte proliferation	103	1.721500	0.0163009	0.0113833
GO:0032943	mononuclear cell proliferation	210	1.721224	0.0163009	0.0113833
GO:0030595	leukocyte chemotaxis	149	1.719725	0.0163009	0.0113833
GO:0010837	regulation of keratinocyte proliferation	28	1.717783	0.0325638	0.0227400
GO:0046651	lymphocyte proliferation	208	1.715920	0.0163009	0.0113833
GO:0009952	anterior/posterior pattern specification	136	1.714609	0.0163009	0.0113833
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	51	1.714336	0.0479310	0.0334712
GO:0034101	erythrocyte homeostasis	105	1.714278	0.0163009	0.0113833
GO:0071634	regulation of transforming growth factor beta production	30	1.713948	0.0325638	0.0227400
GO:0002673	regulation of acute inflammatory response	69	1.713691	0.0163009	0.0113833
GO:0098542	defense response to other organism	314	1.713686	0.0163009	0.0113833
GO:0045066	regulatory T cell differentiation	29	1.713231	0.0325638	0.0227400
GO:0035282	segmentation	70	1.712278	0.0163009	0.0113833
GO:0030449	regulation of complement activation	36	1.712009	0.0399030	0.0278651
GO:2000353	positive regulation of endothelial cell apoptotic process	16	1.711954	0.0467758	0.0326645
GO:0097191	extrinsic apoptotic signaling pathway	192	1.711116	0.0163009	0.0113833
GO:0002699	positive regulation of immune effector process	164	1.709659	0.0163009	0.0113833
GO:0032635	interleukin-6 production	114	1.708735	0.0163009	0.0113833
GO:0060976	coronary vasculature development	43	1.708733	0.0399459	0.0278951
GO:0048593	camera-type eye morphogenesis	99	1.708604	0.0259198	0.0181004
GO:1905314	semi-lunar valve development	33	1.707667	0.0394902	0.0275769
GO:0002224	toll-like receptor signaling pathway	126	1.706628	0.0163009	0.0113833
GO:0002526	acute inflammatory response	111	1.705466	0.0163009	0.0113833
GO:1903426	regulation of reactive oxygen species biosynthetic process	76	1.705132	0.0163009	0.0113833
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	36	1.704823	0.0399030	0.0278651
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	27	1.704792	0.0399030	0.0278651
GO:0032755	positive regulation of interleukin-6 production	67	1.704175	0.0259198	0.0181004
GO:2000181	negative regulation of blood vessel morphogenesis	90	1.703702	0.0163009	0.0113833
GO:0060795	cell fate commitment involved in formation of primary germ layer	25	1.701599	0.0467587	0.0326526
GO:0030857	negative regulation of epithelial cell differentiation	28	1.701021	0.0325638	0.0227400
GO:0071675	regulation of mononuclear cell migration	41	1.700848	0.0468268	0.0327001
GO:0010464	regulation of mesenchymal cell proliferation	32	1.700782	0.0256950	0.0179433
GO:0006606	protein import into nucleus	96	1.700140	0.0259198	0.0181004
GO:0097581	lamellipodium organization	71	1.699903	0.0163009	0.0113833
GO:0007259	JAK-STAT cascade	102	1.699291	0.0163009	0.0113833
GO:0061458	reproductive system development	357	1.698398	0.0163009	0.0113833
GO:0051053	negative regulation of DNA metabolic process	119	1.697216	0.0163009	0.0113833
GO:0048592	eye morphogenesis	126	1.697189	0.0163009	0.0113833
GO:0022409	positive regulation of cell-cell adhesion	206	1.696118	0.0163009	0.0113833
GO:0006956	complement activation	43	1.696047	0.0399459	0.0278951
GO:0003205	cardiac chamber development	148	1.695877	0.0163009	0.0113833
GO:0042088	T-helper 1 type immune response	34	1.695840	0.0468647	0.0327267
GO:0007043	cell-cell junction assembly	88	1.694962	0.0163009	0.0113833
GO:1900015	regulation of cytokine production involved in inflammatory response	34	1.693597	0.0468647	0.0327267
GO:0060537	muscle tissue development	323	1.692796	0.0163009	0.0113833
GO:0071260	cellular response to mechanical stimulus	69	1.692460	0.0259198	0.0181004
GO:0048565	digestive tract development	106	1.692063	0.0163009	0.0113833
GO:0002696	positive regulation of leukocyte activation	255	1.692010	0.0163009	0.0113833
GO:0032946	positive regulation of mononuclear cell proliferation	100	1.691647	0.0163009	0.0113833
GO:0050727	regulation of inflammatory response	299	1.691469	0.0163009	0.0113833
GO:0007435	salivary gland morphogenesis	32	1.691318	0.0394902	0.0275769
GO:0060759	regulation of response to cytokine stimulus	154	1.687517	0.0163009	0.0113833
GO:0060415	muscle tissue morphogenesis	58	1.686603	0.0481798	0.0336450
GO:0007431	salivary gland development	36	1.686508	0.0399030	0.0278651
GO:0048536	spleen development	26	1.686255	0.0399030	0.0278651
GO:0001701	in utero embryonic development	307	1.685789	0.0163009	0.0113833
GO:0050867	positive regulation of cell activation	265	1.684700	0.0163009	0.0113833
GO:0048144	fibroblast proliferation	76	1.684354	0.0163009	0.0113833
GO:0072273	metanephric nephron morphogenesis	25	1.683234	0.0467587	0.0326526
GO:0045668	negative regulation of osteoblast differentiation	36	1.683213	0.0469681	0.0327988
GO:0030279	negative regulation of ossification	57	1.682032	0.0399030	0.0278651
GO:0007423	sensory organ development	449	1.681285	0.0163009	0.0113833
GO:0045216	cell-cell junction organization	116	1.681215	0.0163009	0.0113833
GO:0032945	negative regulation of mononuclear cell proliferation	58	1.681199	0.0481798	0.0336450
GO:0050672	negative regulation of lymphocyte proliferation	58	1.681199	0.0481798	0.0336450
GO:0035270	endocrine system development	93	1.681029	0.0259198	0.0181004
GO:0001959	regulation of cytokine-mediated signaling pathway	143	1.681008	0.0163009	0.0113833
GO:0001501	skeletal system development	394	1.680399	0.0163009	0.0113833
GO:0071354	cellular response to interleukin-6	33	1.677193	0.0464565	0.0324416
GO:0097696	STAT cascade	106	1.676635	0.0163009	0.0113833
GO:0048568	embryonic organ development	338	1.675988	0.0163009	0.0113833
GO:0060348	bone development	163	1.675805	0.0163009	0.0113833
GO:0007517	muscle organ development	327	1.673995	0.0163009	0.0113833
GO:0042035	regulation of cytokine biosynthetic process	83	1.673547	0.0163009	0.0113833
GO:0032570	response to progesterone	40	1.672925	0.0469124	0.0327599
GO:0050871	positive regulation of B cell activation	59	1.672629	0.0408088	0.0284976
GO:0090184	positive regulation of kidney development	32	1.672472	0.0464565	0.0324416
GO:0030218	erythrocyte differentiation	99	1.672314	0.0259198	0.0181004
GO:0070741	response to interleukin-6	36	1.671636	0.0469681	0.0327988
GO:0006303	double-strand break repair via nonhomologous end joining	77	1.671189	0.0163009	0.0113833
GO:0002573	myeloid leukocyte differentiation	166	1.670663	0.0163009	0.0113833
GO:0050671	positive regulation of lymphocyte proliferation	99	1.669844	0.0259198	0.0181004
GO:0090504	epiboly	29	1.668664	0.0397381	0.0277500
GO:0016525	negative regulation of angiogenesis	89	1.666168	0.0259198	0.0181004
GO:0045165	cell fate commitment	173	1.665609	0.0163009	0.0113833
GO:0048710	regulation of astrocyte differentiation	31	1.665507	0.0467758	0.0326645
GO:0070613	regulation of protein processing	83	1.664982	0.0163009	0.0113833
GO:0097421	liver regeneration	29	1.664737	0.0397381	0.0277500
GO:1902532	negative regulation of intracellular signal transduction	461	1.664042	0.0163009	0.0113833
GO:0031348	negative regulation of defense response	170	1.663617	0.0163009	0.0113833
GO:0000726	non-recombinational repair	83	1.663509	0.0163009	0.0113833
GO:0009913	epidermal cell differentiation	153	1.660987	0.0163009	0.0113833
GO:0043433	negative regulation of DNA-binding transcription factor activity	144	1.658615	0.0163009	0.0113833
GO:0050818	regulation of coagulation	64	1.658435	0.0163009	0.0113833
GO:0043409	negative regulation of MAPK cascade	146	1.658242	0.0163009	0.0113833
GO:0031532	actin cytoskeleton reorganization	82	1.657939	0.0259198	0.0181004
GO:0048771	tissue remodeling	133	1.656716	0.0163009	0.0113833
GO:0031099	regeneration	163	1.656489	0.0163009	0.0113833
GO:0031100	animal organ regeneration	67	1.656231	0.0259198	0.0181004
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	276	1.655423	0.0163009	0.0113833
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	204	1.655252	0.0163009	0.0113833
GO:0051384	response to glucocorticoid	119	1.654085	0.0259198	0.0181004
GO:0032651	regulation of interleukin-1 beta production	61	1.654041	0.0334693	0.0233723
GO:0120162	positive regulation of cold-induced thermogenesis	84	1.653133	0.0163009	0.0113833
GO:0030216	keratinocyte differentiation	112	1.653075	0.0259198	0.0181004
GO:2000146	negative regulation of cell motility	238	1.651712	0.0163009	0.0113833
GO:0007173	epidermal growth factor receptor signaling pathway	104	1.646665	0.0163009	0.0113833
GO:0034332	adherens junction organization	129	1.644699	0.0163009	0.0113833
GO:0050663	cytokine secretion	178	1.644155	0.0163009	0.0113833
GO:0071901	negative regulation of protein serine/threonine kinase activity	114	1.643109	0.0259198	0.0181004
GO:0014706	striated muscle tissue development	310	1.641667	0.0163009	0.0113833
GO:0070373	negative regulation of ERK1 and ERK2 cascade	64	1.640789	0.0338318	0.0236255
GO:0031960	response to corticosteroid	135	1.640053	0.0163009	0.0113833
GO:0010810	regulation of cell-substrate adhesion	178	1.639850	0.0163009	0.0113833
GO:0030336	negative regulation of cell migration	227	1.638925	0.0163009	0.0113833
GO:0050920	regulation of chemotaxis	157	1.638685	0.0163009	0.0113833
GO:0001935	endothelial cell proliferation	119	1.638411	0.0259198	0.0181004
GO:0001818	negative regulation of cytokine production	225	1.637597	0.0163009	0.0113833
GO:0030183	B cell differentiation	98	1.636794	0.0259198	0.0181004
GO:0048145	regulation of fibroblast proliferation	75	1.635742	0.0163009	0.0113833
GO:0055123	digestive system development	115	1.635506	0.0259198	0.0181004
GO:0032102	negative regulation of response to external stimulus	258	1.633242	0.0163009	0.0113833
GO:0030522	intracellular receptor signaling pathway	253	1.631735	0.0163009	0.0113833
GO:0002698	negative regulation of immune effector process	99	1.630417	0.0259198	0.0181004
GO:0048705	skeletal system morphogenesis	160	1.630014	0.0163009	0.0113833
GO:0002685	regulation of leukocyte migration	157	1.629967	0.0163009	0.0113833
GO:0019827	stem cell population maintenance	140	1.629590	0.0163009	0.0113833
GO:0000723	telomere maintenance	145	1.628975	0.0163009	0.0113833
GO:0050729	positive regulation of inflammatory response	114	1.628065	0.0259198	0.0181004
GO:0098727	maintenance of cell number	142	1.627375	0.0163009	0.0113833
GO:0030203	glycosaminoglycan metabolic process	143	1.625647	0.0163009	0.0113833
GO:0042326	negative regulation of phosphorylation	396	1.623966	0.0163009	0.0113833
GO:0042113	B cell activation	186	1.623769	0.0163009	0.0113833
GO:1903317	regulation of protein maturation	85	1.623546	0.0163009	0.0113833
GO:0035051	cardiocyte differentiation	112	1.623116	0.0341122	0.0238213
GO:0006909	phagocytosis	219	1.622168	0.0163009	0.0113833
GO:0048738	cardiac muscle tissue development	173	1.621893	0.0163009	0.0113833
GO:0071346	cellular response to interferon-gamma	142	1.618006	0.0163009	0.0113833
GO:0051216	cartilage development	151	1.617303	0.0259198	0.0181004
GO:0051271	negative regulation of cellular component movement	254	1.616671	0.0163009	0.0113833
GO:0016485	protein processing	184	1.615846	0.0163009	0.0113833
GO:0006022	aminoglycan metabolic process	146	1.614960	0.0163009	0.0113833
GO:1901888	regulation of cell junction assembly	86	1.612291	0.0163009	0.0113833
GO:0006986	response to unfolded protein	156	1.611920	0.0259198	0.0181004
GO:0007229	integrin-mediated signaling pathway	90	1.611530	0.0259198	0.0181004
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	120	1.610275	0.0338658	0.0236492
GO:0042542	response to hydrogen peroxide	129	1.609989	0.0336977	0.0235318
GO:0071887	leukocyte apoptotic process	83	1.609179	0.0487739	0.0340598
GO:0001936	regulation of endothelial cell proliferation	104	1.608784	0.0259198	0.0181004
GO:0001819	positive regulation of cytokine production	364	1.606572	0.0163009	0.0113833
GO:0032680	regulation of tumor necrosis factor production	117	1.604140	0.0163009	0.0113833
GO:0002761	regulation of myeloid leukocyte differentiation	93	1.603591	0.0341052	0.0238164
GO:2000045	regulation of G1/S transition of mitotic cell cycle	139	1.603339	0.0332441	0.0232151
GO:0008544	epidermis development	242	1.602838	0.0163009	0.0113833
GO:0046425	regulation of JAK-STAT cascade	87	1.601873	0.0259198	0.0181004
GO:0048545	response to steroid hormone	337	1.601295	0.0163009	0.0113833
GO:0032609	interferon-gamma production	78	1.598320	0.0163009	0.0113833
GO:0097529	myeloid leukocyte migration	136	1.598172	0.0259198	0.0181004
GO:0051701	interaction with host	187	1.597637	0.0163009	0.0113833
GO:0009101	glycoprotein biosynthetic process	265	1.597310	0.0163009	0.0113833
GO:0071706	tumor necrosis factor superfamily cytokine production	125	1.596908	0.0337309	0.0235550
GO:0002688	regulation of leukocyte chemotaxis	89	1.596103	0.0259198	0.0181004
GO:0050707	regulation of cytokine secretion	153	1.595940	0.0259198	0.0181004
GO:0048872	homeostasis of number of cells	212	1.595358	0.0163009	0.0113833
GO:0040013	negative regulation of locomotion	265	1.595025	0.0163009	0.0113833
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	119	1.592729	0.0259198	0.0181004
GO:0001659	temperature homeostasis	152	1.592354	0.0259198	0.0181004
GO:0048010	vascular endothelial growth factor receptor signaling pathway	87	1.591525	0.0259198	0.0181004
GO:0007569	cell aging	99	1.590731	0.0341052	0.0238164
GO:0001776	leukocyte homeostasis	74	1.589042	0.0336977	0.0235318
GO:0045444	fat cell differentiation	192	1.587415	0.0163009	0.0113833
GO:0001933	negative regulation of protein phosphorylation	363	1.585326	0.0163009	0.0113833
GO:0043588	skin development	214	1.585202	0.0163009	0.0113833
GO:1905952	regulation of lipid localization	115	1.583176	0.0259198	0.0181004
GO:1904892	regulation of STAT cascade	90	1.579647	0.0341122	0.0238213
GO:0070371	ERK1 and ERK2 cascade	241	1.579013	0.0163009	0.0113833
GO:0034333	adherens junction assembly	88	1.578991	0.0420626	0.0293732
GO:0032526	response to retinoic acid	93	1.577909	0.0341052	0.0238164
GO:0106106	cold-induced thermogenesis	129	1.573761	0.0486648	0.0339837
GO:0120161	regulation of cold-induced thermogenesis	129	1.573761	0.0486648	0.0339837
GO:0010001	glial cell differentiation	200	1.571772	0.0163009	0.0113833
GO:0006959	humoral immune response	119	1.569872	0.0337643	0.0235784
GO:0007265	Ras protein signal transduction	314	1.568428	0.0163009	0.0113833
GO:0035265	organ growth	138	1.566270	0.0479310	0.0334712
GO:1901184	regulation of ERBB signaling pathway	83	1.565565	0.0487739	0.0340598
GO:0032640	tumor necrosis factor production	121	1.565178	0.0414987	0.0289794
GO:0002009	morphogenesis of an epithelium	461	1.564542	0.0163009	0.0113833
GO:0007266	Rho protein signal transduction	151	1.563486	0.0259198	0.0181004
GO:0043009	chordate embryonic development	496	1.560149	0.0163009	0.0113833
GO:0051090	regulation of DNA-binding transcription factor activity	377	1.559297	0.0163009	0.0113833
GO:0006493	protein O-linked glycosylation	87	1.558964	0.0493729	0.0344781
GO:0001906	cell killing	94	1.552809	0.0341096	0.0238195
GO:0033673	negative regulation of kinase activity	214	1.549712	0.0163009	0.0113833
GO:0051170	import into nucleus	117	1.549609	0.0259198	0.0181004
GO:0006469	negative regulation of protein kinase activity	197	1.548833	0.0163009	0.0113833
GO:0019216	regulation of lipid metabolic process	339	1.543705	0.0163009	0.0113833
GO:0001101	response to acid chemical	298	1.543320	0.0163009	0.0113833
GO:0042063	gliogenesis	262	1.541951	0.0163009	0.0113833
GO:1902806	regulation of cell cycle G1/S phase transition	152	1.539691	0.0259198	0.0181004
GO:1903409	reactive oxygen species biosynthetic process	96	1.538200	0.0419599	0.0293015
GO:0062014	negative regulation of small molecule metabolic process	84	1.533317	0.0494299	0.0345180
GO:2000377	regulation of reactive oxygen species metabolic process	161	1.527025	0.0259198	0.0181004
GO:0045936	negative regulation of phosphate metabolic process	498	1.522672	0.0163009	0.0113833
GO:0051146	striated muscle cell differentiation	212	1.518334	0.0163009	0.0113833
GO:2001020	regulation of response to DNA damage stimulus	194	1.517527	0.0256950	0.0179433
GO:0070372	regulation of ERK1 and ERK2 cascade	226	1.513326	0.0163009	0.0113833
GO:0090596	sensory organ morphogenesis	207	1.509917	0.0163009	0.0113833
GO:0010563	negative regulation of phosphorus metabolic process	499	1.509790	0.0163009	0.0113833
GO:0007219	Notch signaling pathway	157	1.504911	0.0259198	0.0181004
GO:0035966	response to topologically incorrect protein	170	1.500023	0.0163009	0.0113833
GO:1901652	response to peptide	433	1.497208	0.0163009	0.0113833
GO:0071407	cellular response to organic cyclic compound	489	1.495282	0.0163009	0.0113833
GO:0042330	taxis	461	1.489261	0.0163009	0.0113833
GO:0006302	double-strand break repair	200	1.477868	0.0256950	0.0179433
GO:0006935	chemotaxis	459	1.475953	0.0163009	0.0113833
GO:0009612	response to mechanical stimulus	180	1.475874	0.0259198	0.0181004
GO:0007568	aging	276	1.472302	0.0259198	0.0181004
GO:0043583	ear development	180	1.465610	0.0259198	0.0181004
GO:0043405	regulation of MAP kinase activity	293	1.462833	0.0256950	0.0179433
GO:2001234	negative regulation of apoptotic signaling pathway	199	1.460054	0.0325638	0.0227400
GO:0009100	glycoprotein metabolic process	321	1.459553	0.0163009	0.0113833
GO:0043434	response to peptide hormone	359	1.454162	0.0163009	0.0113833
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	176	1.453980	0.0163009	0.0113833
GO:2000116	regulation of cysteine-type endopeptidase activity	200	1.451070	0.0325638	0.0227400
GO:0000302	response to reactive oxygen species	204	1.448319	0.0256950	0.0179433
GO:0071214	cellular response to abiotic stimulus	277	1.438212	0.0258183	0.0180295
GO:0104004	cellular response to environmental stimulus	277	1.438212	0.0258183	0.0180295
GO:0045088	regulation of innate immune response	367	1.436410	0.0163009	0.0113833
GO:0051604	protein maturation	238	1.432332	0.0163009	0.0113833
GO:2001233	regulation of apoptotic signaling pathway	360	1.425854	0.0163009	0.0113833
GO:0042119	neutrophil activation	442	1.425386	0.0163009	0.0113833
GO:0052547	regulation of peptidase activity	311	1.424759	0.0256950	0.0179433
GO:0007548	sex differentiation	219	1.423387	0.0325638	0.0227400
GO:0002446	neutrophil mediated immunity	442	1.420592	0.0163009	0.0113833
GO:0043410	positive regulation of MAPK cascade	430	1.420062	0.0163009	0.0113833
GO:0002253	activation of immune response	482	1.418634	0.0163009	0.0113833
GO:0097193	intrinsic apoptotic signaling pathway	252	1.413788	0.0325638	0.0227400
GO:0071383	cellular response to steroid hormone stimulus	224	1.413623	0.0325638	0.0227400
GO:0046578	regulation of Ras protein signal transduction	208	1.407638	0.0399857	0.0279229
GO:0048562	embryonic organ morphogenesis	217	1.404412	0.0399030	0.0278651
GO:1901653	cellular response to peptide	322	1.402946	0.0391379	0.0273308
GO:0036230	granulocyte activation	449	1.392785	0.0163009	0.0113833
GO:0043312	neutrophil degranulation	431	1.389726	0.0163009	0.0113833
GO:0002283	neutrophil activation involved in immune response	433	1.388856	0.0163009	0.0113833
GO:0000082	G1/S transition of mitotic cell cycle	229	1.388597	0.0468647	0.0327267
GO:0072593	reactive oxygen species metabolic process	229	1.387864	0.0468647	0.0327267
GO:0045926	negative regulation of growth	211	1.386956	0.0399030	0.0278651
GO:0052548	regulation of endopeptidase activity	287	1.384939	0.0468647	0.0327267
GO:0007264	small GTPase mediated signal transduction	449	1.383349	0.0163009	0.0113833
GO:0071900	regulation of protein serine/threonine kinase activity	433	1.378355	0.0163009	0.0113833
GO:0044843	cell cycle G1/S phase transition	243	1.376693	0.0399030	0.0278651
GO:0090287	regulation of cellular response to growth factor stimulus	225	1.372181	0.0473740	0.0330823
GO:0051348	negative regulation of transferase activity	241	1.367540	0.0469681	0.0327988
GO:0048871	multicellular organismal homeostasis	393	1.362653	0.0384836	0.0268740
GO:0043299	leukocyte degranulation	475	1.355314	0.0256950	0.0179433
GO:0031349	positive regulation of defense response	415	1.352573	0.0325638	0.0227400
GO:0002444	myeloid leukocyte mediated immunity	490	1.342794	0.0256950	0.0179433
GO:0002275	myeloid cell activation involved in immune response	483	1.338694	0.0256950	0.0179433

Enriched terms for module #EE8045 (MTcor = 0.93)

ID	Description	setSize	NES	p.adjust	qvalues
GO:0006335	DNA replication-dependent nucleosome assembly	32	2.996751	0.0159016	0.0102626
GO:0034723	DNA replication-dependent nucleosome organization	32	2.996751	0.0159016	0.0102626
GO:0000183	chromatin silencing at rDNA	39	2.777755	0.0159016	0.0102626
GO:0030219	megakaryocyte differentiation	90	2.673639	0.0159016	0.0102626
GO:0045652	regulation of megakaryocyte differentiation	74	2.668044	0.0159016	0.0102626
GO:0045653	negative regulation of megakaryocyte differentiation	17	2.640593	0.0159016	0.0102626
GO:0046637	regulation of alpha-beta T cell differentiation	51	2.599135	0.0159016	0.0102626
GO:0002250	adaptive immune response	290	2.578289	0.0159016	0.0102626
GO:0051290	protein heterotetramerization	51	2.569952	0.0159016	0.0102626
GO:1902107	positive regulation of leukocyte differentiation	122	2.565363	0.0159016	0.0102626
GO:0002819	regulation of adaptive immune response	128	2.547999	0.0159016	0.0102626
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	37	2.545056	0.0159016	0.0102626
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	46	2.521920	0.0159016	0.0102626
GO:0045621	positive regulation of lymphocyte differentiation	81	2.519959	0.0159016	0.0102626
GO:0046634	regulation of alpha-beta T cell activation	74	2.495200	0.0159016	0.0102626
GO:0006334	nucleosome assembly	119	2.491964	0.0159016	0.0102626
GO:1903708	positive regulation of hemopoiesis	155	2.475645	0.0159016	0.0102626
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	197	2.468648	0.0159016	0.0102626
GO:0046638	positive regulation of alpha-beta T cell differentiation	40	2.468390	0.0159016	0.0102626
GO:1903707	negative regulation of hemopoiesis	129	2.465092	0.0159016	0.0102626
GO:0045582	positive regulation of T cell differentiation	71	2.462210	0.0159016	0.0102626
GO:0042129	regulation of T cell proliferation	123	2.446160	0.0159016	0.0102626
GO:0070663	regulation of leukocyte proliferation	177	2.437859	0.0159016	0.0102626
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	114	2.437506	0.0159016	0.0102626
GO:0046631	alpha-beta T cell activation	107	2.428381	0.0159016	0.0102626
GO:0042098	T cell proliferation	151	2.424494	0.0159016	0.0102626
GO:0032944	regulation of mononuclear cell proliferation	169	2.420905	0.0159016	0.0102626
GO:0051250	negative regulation of lymphocyte activation	117	2.413892	0.0159016	0.0102626
GO:0046635	positive regulation of alpha-beta T cell activation	51	2.413465	0.0159016	0.0102626
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	23	2.410038	0.0159016	0.0102626
GO:0045622	regulation of T-helper cell differentiation	27	2.404610	0.0159016	0.0102626
GO:0050670	regulation of lymphocyte proliferation	168	2.400951	0.0159016	0.0102626
GO:1902105	regulation of leukocyte differentiation	223	2.391644	0.0159016	0.0102626
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	18	2.387865	0.0159016	0.0102626
GO:0002821	positive regulation of adaptive immune response	78	2.387704	0.0159016	0.0102626
GO:0042110	T cell activation	376	2.385384	0.0159016	0.0102626
GO:0034728	nucleosome organization	144	2.382611	0.0159016	0.0102626
GO:0031497	chromatin assembly	135	2.382550	0.0159016	0.0102626
GO:0045580	regulation of T cell differentiation	117	2.363514	0.0159016	0.0102626
GO:0046632	alpha-beta T cell differentiation	78	2.363269	0.0159016	0.0102626
GO:0002385	mucosal immune response	14	2.360574	0.0159016	0.0102626
GO:0045619	regulation of lymphocyte differentiation	139	2.357851	0.0159016	0.0102626
GO:0046639	negative regulation of alpha-beta T cell differentiation	21	2.355658	0.0159016	0.0102626
GO:0043367	CD4-positive, alpha-beta T cell differentiation	58	2.353200	0.0159016	0.0102626
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	73	2.352232	0.0159016	0.0102626
GO:0070661	leukocyte proliferation	227	2.347786	0.0159016	0.0102626
GO:0045637	regulation of myeloid cell differentiation	214	2.342380	0.0159016	0.0102626
GO:0030217	T cell differentiation	193	2.336414	0.0159016	0.0102626
GO:0002695	negative regulation of leukocyte activation	143	2.335048	0.0159016	0.0102626
GO:0050863	regulation of T cell activation	259	2.334270	0.0159016	0.0102626
GO:0002285	lymphocyte activation involved in immune response	128	2.329127	0.0159016	0.0102626
GO:0032943	mononuclear cell proliferation	210	2.328515	0.0159016	0.0102626
GO:0050866	negative regulation of cell activation	162	2.325771	0.0159016	0.0102626
GO:0050853	B cell receptor signaling pathway	43	2.324354	0.0159016	0.0102626
GO:0030199	collagen fibril organization	40	2.319824	0.0159016	0.0102626
GO:0046651	lymphocyte proliferation	208	2.315219	0.0159016	0.0102626
GO:0006342	chromatin silencing	76	2.311585	0.0159016	0.0102626
GO:0007159	leukocyte cell-cell adhesion	272	2.310113	0.0159016	0.0102626
GO:0046636	negative regulation of alpha-beta T cell activation	31	2.307623	0.0159016	0.0102626
GO:0002286	T cell activation involved in immune response	70	2.303469	0.0159016	0.0102626
GO:0035710	CD4-positive, alpha-beta T cell activation	71	2.301925	0.0159016	0.0102626
GO:0006333	chromatin assembly or disassembly	159	2.301213	0.0159016	0.0102626
GO:0051249	regulation of lymphocyte activation	345	2.296515	0.0159016	0.0102626
GO:0050868	negative regulation of T cell activation	89	2.294916	0.0159016	0.0102626
GO:0022408	negative regulation of cell-cell adhesion	138	2.292432	0.0159016	0.0102626
GO:1903037	regulation of leukocyte cell-cell adhesion	244	2.285001	0.0159016	0.0102626
GO:0030098	lymphocyte differentiation	272	2.282246	0.0159016	0.0102626
GO:1903038	negative regulation of leukocyte cell-cell adhesion	98	2.280447	0.0159016	0.0102626
GO:0002227	innate immune response in mucosa	11	2.268398	0.0162534	0.0104897
GO:1903039	positive regulation of leukocyte cell-cell adhesion	178	2.268072	0.0159016	0.0102626
GO:0060964	regulation of gene silencing by miRNA	110	2.265707	0.0159016	0.0102626
GO:0002449	lymphocyte mediated immunity	187	2.264338	0.0159016	0.0102626
GO:0002467	germinal center formation	14	2.264219	0.0159016	0.0102626
GO:0002694	regulation of leukocyte activation	420	2.263749	0.0159016	0.0102626
GO:0070664	negative regulation of leukocyte proliferation	63	2.263131	0.0159016	0.0102626
GO:0007492	endoderm development	60	2.260271	0.0159016	0.0102626
GO:0060333	interferon-gamma-mediated signaling pathway	83	2.258355	0.0159016	0.0102626
GO:0002683	negative regulation of immune system process	376	2.255517	0.0159016	0.0102626
GO:1902106	negative regulation of leukocyte differentiation	84	2.252447	0.0159016	0.0102626
GO:0002251	organ or tissue specific immune response	17	2.251300	0.0159016	0.0102626
GO:0034508	centromere complex assembly	53	2.243692	0.0159016	0.0102626
GO:0050870	positive regulation of T cell activation	165	2.241986	0.0159016	0.0102626
GO:0060326	cell chemotaxis	201	2.238333	0.0159016	0.0102626
GO:0042102	positive regulation of T cell proliferation	69	2.237726	0.0159016	0.0102626
GO:0045581	negative regulation of T cell differentiation	38	2.233343	0.0159016	0.0102626
GO:0050865	regulation of cell activation	453	2.231562	0.0159016	0.0102626
GO:0002521	leukocyte differentiation	407	2.231494	0.0159016	0.0102626
GO:0060147	regulation of posttranscriptional gene silencing	112	2.229272	0.0159016	0.0102626
GO:0060966	regulation of gene silencing by RNA	112	2.229272	0.0159016	0.0102626
GO:0002577	regulation of antigen processing and presentation	15	2.227794	0.0159016	0.0102626
GO:0048514	blood vessel morphogenesis	495	2.224973	0.0159016	0.0102626
GO:0045624	positive regulation of T-helper cell differentiation	17	2.224029	0.0159016	0.0102626
GO:0032677	regulation of interleukin-8 production	53	2.217004	0.0159016	0.0102626
GO:0016064	immunoglobulin mediated immune response	86	2.214410	0.0159016	0.0102626
GO:0032945	negative regulation of mononuclear cell proliferation	58	2.211020	0.0159016	0.0102626
GO:0050672	negative regulation of lymphocyte proliferation	58	2.211020	0.0159016	0.0102626
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	24	2.209178	0.0159016	0.0102626
GO:0006323	DNA packaging	168	2.206612	0.0159016	0.0102626
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	28	2.206398	0.0159016	0.0102626
GO:0019731	antibacterial humoral response	20	2.205999	0.0159016	0.0102626
GO:0045066	regulatory T cell differentiation	29	2.203715	0.0159016	0.0102626
GO:0002703	regulation of leukocyte mediated immunity	155	2.201637	0.0159016	0.0102626
GO:0019724	B cell mediated immunity	88	2.201544	0.0159016	0.0102626
GO:0045616	regulation of keratinocyte differentiation	30	2.198550	0.0159016	0.0102626
GO:0002696	positive regulation of leukocyte activation	255	2.197440	0.0159016	0.0102626
GO:0050867	positive regulation of cell activation	265	2.196000	0.0159016	0.0102626
GO:0045814	negative regulation of gene expression, epigenetic	94	2.195384	0.0159016	0.0102626
GO:0010718	positive regulation of epithelial to mesenchymal transition	45	2.192845	0.0159016	0.0102626
GO:0022407	regulation of cell-cell adhesion	321	2.192025	0.0159016	0.0102626
GO:0001710	mesodermal cell fate commitment	15	2.191462	0.0159016	0.0102626
GO:0002706	regulation of lymphocyte mediated immunity	109	2.186002	0.0159016	0.0102626
GO:0006968	cellular defense response	40	2.185394	0.0159016	0.0102626
GO:0045638	negative regulation of myeloid cell differentiation	79	2.183768	0.0159016	0.0102626
GO:0051251	positive regulation of lymphocyte activation	218	2.180389	0.0159016	0.0102626
GO:0030099	myeloid cell differentiation	357	2.180262	0.0159016	0.0102626
GO:0002287	alpha-beta T cell activation involved in immune response	47	2.177864	0.0159016	0.0102626
GO:0002293	alpha-beta T cell differentiation involved in immune response	47	2.177864	0.0159016	0.0102626
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	47	2.177864	0.0159016	0.0102626
GO:0002697	regulation of immune effector process	310	2.176051	0.0159016	0.0102626
GO:0002292	T cell differentiation involved in immune response	49	2.174498	0.0159016	0.0102626
GO:0042113	B cell activation	186	2.172635	0.0159016	0.0102626
GO:0001704	formation of primary germ layer	95	2.165954	0.0159016	0.0102626
GO:0009617	response to bacterium	413	2.162041	0.0159016	0.0102626
GO:0022409	positive regulation of cell-cell adhesion	206	2.159242	0.0159016	0.0102626
GO:1903706	regulation of hemopoiesis	409	2.155280	0.0159016	0.0102626
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	13	2.154887	0.0159016	0.0102626
GO:0003272	endocardial cushion formation	23	2.152902	0.0159016	0.0102626
GO:0031055	chromatin remodeling at centromere	45	2.151889	0.0159016	0.0102626
GO:0042093	T-helper cell differentiation	46	2.151698	0.0159016	0.0102626
GO:0001773	myeloid dendritic cell activation	21	2.151516	0.0159016	0.0102626
GO:0048333	mesodermal cell differentiation	27	2.148310	0.0159016	0.0102626
GO:0045589	regulation of regulatory T cell differentiation	28	2.147716	0.0159016	0.0102626
GO:0032060	bleb assembly	11	2.146013	0.0162534	0.0104897
GO:0070665	positive regulation of leukocyte proliferation	103	2.145809	0.0159016	0.0102626
GO:2000482	regulation of interleukin-8 secretion	20	2.144121	0.0159016	0.0102626
GO:0050864	regulation of B cell activation	97	2.140673	0.0159016	0.0102626
GO:0046633	alpha-beta T cell proliferation	26	2.136271	0.0159016	0.0102626
GO:0045620	negative regulation of lymphocyte differentiation	44	2.134582	0.0159016	0.0102626
GO:2000036	regulation of stem cell population maintenance	25	2.132358	0.0159016	0.0102626
GO:0038111	interleukin-7-mediated signaling pathway	29	2.129577	0.0159016	0.0102626
GO:0001525	angiogenesis	418	2.124523	0.0159016	0.0102626
GO:0035329	hippo signaling	38	2.122046	0.0159016	0.0102626
GO:0045623	negative regulation of T-helper cell differentiation	14	2.121473	0.0159016	0.0102626
GO:2000319	regulation of T-helper 17 cell differentiation	13	2.120336	0.0159016	0.0102626
GO:0034341	response to interferon-gamma	159	2.112033	0.0159016	0.0102626
GO:0032729	positive regulation of interferon-gamma production	46	2.111243	0.0159016	0.0102626
GO:0032946	positive regulation of mononuclear cell proliferation	100	2.110927	0.0159016	0.0102626
GO:0043486	histone exchange	50	2.110727	0.0159016	0.0102626
GO:0009595	detection of biotic stimulus	17	2.107029	0.0159016	0.0102626
GO:0007162	negative regulation of cell adhesion	223	2.105805	0.0159016	0.0102626
GO:0051291	protein heterooligomerization	120	2.103920	0.0159016	0.0102626
GO:0002064	epithelial cell development	175	2.102489	0.0159016	0.0102626
GO:0045785	positive regulation of cell adhesion	334	2.098971	0.0159016	0.0102626
GO:1904018	positive regulation of vasculature development	161	2.096105	0.0159016	0.0102626
GO:0003158	endothelium development	106	2.096033	0.0159016	0.0102626
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	23	2.092080	0.0159016	0.0102626
GO:0006911	phagocytosis, engulfment	40	2.091847	0.0159016	0.0102626
GO:0050671	positive regulation of lymphocyte proliferation	99	2.088629	0.0159016	0.0102626
GO:0060968	regulation of gene silencing	132	2.088293	0.0159016	0.0102626
GO:0002237	response to molecule of bacterial origin	260	2.086782	0.0159016	0.0102626
GO:0002507	tolerance induction	18	2.083241	0.0159016	0.0102626
GO:0032637	interleukin-8 production	58	2.082901	0.0159016	0.0102626
GO:0034080	CENP-A containing nucleosome assembly	41	2.080170	0.0159016	0.0102626
GO:0061641	CENP-A containing chromatin organization	41	2.080170	0.0159016	0.0102626
GO:0032757	positive regulation of interleukin-8 production	36	2.079433	0.0159016	0.0102626
GO:2001026	regulation of endothelial cell chemotaxis	17	2.077567	0.0159016	0.0102626
GO:2000050	regulation of non-canonical Wnt signaling pathway	22	2.076022	0.0159016	0.0102626
GO:0065004	protein-DNA complex assembly	191	2.073912	0.0159016	0.0102626
GO:0030183	B cell differentiation	98	2.073187	0.0159016	0.0102626
GO:0008360	regulation of cell shape	118	2.073166	0.0159016	0.0102626
GO:0030856	regulation of epithelial cell differentiation	112	2.071347	0.0159016	0.0102626
GO:0002708	positive regulation of lymphocyte mediated immunity	72	2.071081	0.0159016	0.0102626
GO:0072160	nephron tubule epithelial cell differentiation	13	2.070807	0.0159016	0.0102626
GO:0072574	hepatocyte proliferation	16	2.069090	0.0159016	0.0102626
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	16	2.069090	0.0159016	0.0102626
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	37	2.068410	0.0159016	0.0102626
GO:0060795	cell fate commitment involved in formation of primary germ layer	25	2.067592	0.0159016	0.0102626
GO:0016233	telomere capping	49	2.067202	0.0159016	0.0102626
GO:0035767	endothelial cell chemotaxis	24	2.067169	0.0159016	0.0102626
GO:2000316	regulation of T-helper 17 type immune response	15	2.066747	0.0159016	0.0102626
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	34	2.066536	0.0159016	0.0102626
GO:0043484	regulation of RNA splicing	106	2.061311	0.0159016	0.0102626
GO:0050854	regulation of antigen receptor-mediated signaling pathway	50	2.058590	0.0159016	0.0102626
GO:0071216	cellular response to biotic stimulus	178	2.056995	0.0159016	0.0102626
GO:0006336	DNA replication-independent nucleosome assembly	52	2.052734	0.0159016	0.0102626
GO:0034724	DNA replication-independent nucleosome organization	52	2.052734	0.0159016	0.0102626
GO:0033622	integrin activation	19	2.051575	0.0159016	0.0102626
GO:0014855	striated muscle cell proliferation	58	2.049696	0.0159016	0.0102626
GO:0071346	cellular response to interferon-gamma	142	2.047801	0.0159016	0.0102626
GO:2000826	regulation of heart morphogenesis	32	2.045632	0.0159016	0.0102626
GO:0010452	histone H3-K36 methylation	12	2.043796	0.0159016	0.0102626
GO:0002699	positive regulation of immune effector process	164	2.040104	0.0159016	0.0102626
GO:0003151	outflow tract morphogenesis	70	2.038889	0.0159016	0.0102626
GO:0061053	somite development	65	2.036500	0.0159016	0.0102626
GO:0001756	somitogenesis	49	2.035314	0.0159016	0.0102626
GO:2000737	negative regulation of stem cell differentiation	19	2.034768	0.0159016	0.0102626
GO:0097150	neuronal stem cell population maintenance	22	2.033552	0.0159016	0.0102626
GO:0032496	response to lipopolysaccharide	248	2.033551	0.0159016	0.0102626
GO:0007498	mesoderm development	100	2.033095	0.0159016	0.0102626
GO:0030449	regulation of complement activation	36	2.033087	0.0159016	0.0102626
GO:0050777	negative regulation of immune response	116	2.031395	0.0159016	0.0102626
GO:0030198	extracellular matrix organization	286	2.031014	0.0159016	0.0102626
GO:2000257	regulation of protein activation cascade	37	2.030388	0.0159016	0.0102626
GO:0034968	histone lysine methylation	100	2.028889	0.0159016	0.0102626
GO:0050830	defense response to Gram-positive bacterium	45	2.023377	0.0159016	0.0102626
GO:0071675	regulation of mononuclear cell migration	41	2.020780	0.0159016	0.0102626
GO:0016441	posttranscriptional gene silencing	155	2.020633	0.0159016	0.0102626
GO:0046640	regulation of alpha-beta T cell proliferation	23	2.020561	0.0159016	0.0102626
GO:0035195	gene silencing by miRNA	150	2.020028	0.0159016	0.0102626
GO:0043044	ATP-dependent chromatin remodeling	72	2.018077	0.0159016	0.0102626
GO:1904036	negative regulation of epithelial cell apoptotic process	30	2.017284	0.0159016	0.0102626
GO:0045446	endothelial cell differentiation	88	2.015375	0.0159016	0.0102626
GO:0045649	regulation of macrophage differentiation	19	2.013752	0.0159016	0.0102626
GO:0002761	regulation of myeloid leukocyte differentiation	93	2.010662	0.0159016	0.0102626
GO:0007369	gastrulation	146	2.009882	0.0159016	0.0102626
GO:0045579	positive regulation of B cell differentiation	11	2.007057	0.0162534	0.0104897
GO:0072132	mesenchyme morphogenesis	47	2.006785	0.0159016	0.0102626
GO:0071824	protein-DNA complex subunit organization	216	2.006527	0.0159016	0.0102626
GO:0006956	complement activation	43	2.005610	0.0159016	0.0102626
GO:0008340	determination of adult lifespan	14	2.003847	0.0159016	0.0102626
GO:1904035	regulation of epithelial cell apoptotic process	61	2.002353	0.0159016	0.0102626
GO:0016577	histone demethylation	24	2.001585	0.0159016	0.0102626
GO:0098581	detection of external biotic stimulus	13	2.000402	0.0159016	0.0102626
GO:0045778	positive regulation of ossification	85	2.000043	0.0159016	0.0102626
GO:0045639	positive regulation of myeloid cell differentiation	71	2.000001	0.0159016	0.0102626
GO:0050900	leukocyte migration	335	1.998014	0.0159016	0.0102626
GO:0045766	positive regulation of angiogenesis	143	1.997812	0.0159016	0.0102626
GO:0007229	integrin-mediated signaling pathway	90	1.996853	0.0159016	0.0102626
GO:0002920	regulation of humoral immune response	46	1.996339	0.0159016	0.0102626
GO:0035194	posttranscriptional gene silencing by RNA	154	1.996125	0.0159016	0.0102626
GO:0045604	regulation of epidermal cell differentiation	45	1.994987	0.0159016	0.0102626
GO:1905523	positive regulation of macrophage migration	19	1.993109	0.0159016	0.0102626
GO:0043011	myeloid dendritic cell differentiation	14	1.992992	0.0159016	0.0102626
GO:0003382	epithelial cell morphogenesis	25	1.991944	0.0159016	0.0102626
GO:0042089	cytokine biosynthetic process	89	1.991620	0.0159016	0.0102626
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	65	1.990390	0.0159016	0.0102626
GO:0071219	cellular response to molecule of bacterial origin	155	1.990373	0.0159016	0.0102626
GO:0042060	wound healing	458	1.990057	0.0159016	0.0102626
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	39	1.990055	0.0159016	0.0102626
GO:0072576	liver morphogenesis	17	1.989076	0.0159016	0.0102626
GO:0030225	macrophage differentiation	38	1.988708	0.0159016	0.0102626
GO:0003229	ventricular cardiac muscle tissue development	45	1.988014	0.0159016	0.0102626
GO:0060411	cardiac septum morphogenesis	67	1.988007	0.0159016	0.0102626
GO:0042107	cytokine metabolic process	90	1.987084	0.0159016	0.0102626
GO:0042130	negative regulation of T cell proliferation	47	1.986294	0.0159016	0.0102626
GO:0002714	positive regulation of B cell mediated immunity	28	1.985472	0.0159016	0.0102626
GO:0002891	positive regulation of immunoglobulin mediated immune response	28	1.985472	0.0159016	0.0102626
GO:0002673	regulation of acute inflammatory response	69	1.985236	0.0159016	0.0102626
GO:2000677	regulation of transcription regulatory region DNA binding	42	1.983749	0.0159016	0.0102626
GO:0002712	regulation of B cell mediated immunity	40	1.983496	0.0159016	0.0102626
GO:0002889	regulation of immunoglobulin mediated immune response	40	1.983496	0.0159016	0.0102626
GO:0110110	positive regulation of animal organ morphogenesis	69	1.983304	0.0159016	0.0102626
GO:0010575	positive regulation of vascular endothelial growth factor production	24	1.982622	0.0159016	0.0102626
GO:0048332	mesoderm morphogenesis	57	1.981666	0.0159016	0.0102626
GO:0045628	regulation of T-helper 2 cell differentiation	11	1.981046	0.0162534	0.0104897
GO:1901342	regulation of vasculature development	274	1.980583	0.0159016	0.0102626
GO:0042116	macrophage activation	78	1.980234	0.0159016	0.0102626
GO:0006959	humoral immune response	119	1.979436	0.0159016	0.0102626
GO:2000679	positive regulation of transcription regulatory region DNA binding	19	1.979197	0.0159016	0.0102626
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	17	1.979054	0.0159016	0.0102626
GO:0014842	regulation of skeletal muscle satellite cell proliferation	12	1.978968	0.0159016	0.0102626
GO:0071222	cellular response to lipopolysaccharide	148	1.976056	0.0159016	0.0102626
GO:0042742	defense response to bacterium	120	1.975638	0.0159016	0.0102626
GO:0002763	positive regulation of myeloid leukocyte differentiation	41	1.975124	0.0159016	0.0102626
GO:0032623	interleukin-2 production	54	1.974236	0.0159016	0.0102626
GO:0099024	plasma membrane invagination	48	1.972812	0.0159016	0.0102626
GO:0050798	activated T cell proliferation	31	1.972576	0.0159016	0.0102626
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	36	1.971354	0.0159016	0.0102626
GO:0072606	interleukin-8 secretion	23	1.970205	0.0159016	0.0102626
GO:0061614	pri-miRNA transcription by RNA polymerase II	43	1.969405	0.0159016	0.0102626
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	29	1.967972	0.0159016	0.0102626
GO:0048644	muscle organ morphogenesis	62	1.967900	0.0159016	0.0102626
GO:2001236	regulation of extrinsic apoptotic signaling pathway	137	1.967410	0.0159016	0.0102626
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	35	1.967118	0.0159016	0.0102626
GO:0050702	interleukin-1 beta secretion	42	1.963622	0.0159016	0.0102626
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	22	1.961361	0.0159016	0.0102626
GO:0030855	epithelial cell differentiation	481	1.957537	0.0159016	0.0102626
GO:0022612	gland morphogenesis	101	1.957471	0.0159016	0.0102626
GO:0050920	regulation of chemotaxis	157	1.956884	0.0159016	0.0102626
GO:0003279	cardiac septum development	101	1.956674	0.0159016	0.0102626
GO:0035987	endodermal cell differentiation	38	1.956129	0.0159016	0.0102626
GO:0032663	regulation of interleukin-2 production	46	1.954072	0.0159016	0.0102626
GO:0001706	endoderm formation	42	1.953888	0.0159016	0.0102626
GO:0060142	regulation of syncytium formation by plasma membrane fusion	21	1.953618	0.0159016	0.0102626
GO:0050869	negative regulation of B cell activation	28	1.951449	0.0159016	0.0102626
GO:0030595	leukocyte chemotaxis	149	1.950895	0.0159016	0.0102626
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	10	1.950753	0.0204307	0.0131856
GO:0045682	regulation of epidermis development	63	1.950337	0.0159016	0.0102626
GO:1990776	response to angiotensin	25	1.949864	0.0159016	0.0102626
GO:0035282	segmentation	70	1.949668	0.0159016	0.0102626
GO:0003170	heart valve development	54	1.949245	0.0159016	0.0102626
GO:0002705	positive regulation of leukocyte mediated immunity	97	1.948220	0.0159016	0.0102626
GO:0002573	myeloid leukocyte differentiation	166	1.947939	0.0159016	0.0102626
GO:0050713	negative regulation of interleukin-1 beta secretion	10	1.945093	0.0204307	0.0131856
GO:0045064	T-helper 2 cell differentiation	12	1.944399	0.0159016	0.0102626
GO:0001707	mesoderm formation	55	1.943634	0.0159016	0.0102626
GO:0098760	response to interleukin-7	40	1.943011	0.0159016	0.0102626
GO:0098761	cellular response to interleukin-7	40	1.943011	0.0159016	0.0102626
GO:0072182	regulation of nephron tubule epithelial cell differentiation	11	1.941712	0.0162534	0.0104897
GO:0046641	positive regulation of alpha-beta T cell proliferation	14	1.941564	0.0159016	0.0102626
GO:0018022	peptidyl-lysine methylation	112	1.941119	0.0159016	0.0102626
GO:0032609	interferon-gamma production	78	1.940796	0.0159016	0.0102626
GO:0002548	monocyte chemotaxis	33	1.940102	0.0159016	0.0102626
GO:0043062	extracellular structure organization	330	1.939101	0.0159016	0.0102626
GO:0070076	histone lysine demethylation	23	1.938599	0.0159016	0.0102626
GO:0046831	regulation of RNA export from nucleus	11	1.937940	0.0162534	0.0104897
GO:0042035	regulation of cytokine biosynthetic process	83	1.936657	0.0159016	0.0102626
GO:0014857	regulation of skeletal muscle cell proliferation	13	1.935150	0.0159016	0.0102626
GO:0031047	gene silencing by RNA	174	1.934478	0.0159016	0.0102626
GO:0060977	coronary vasculature morphogenesis	14	1.932245	0.0159016	0.0102626
GO:0090195	chemokine secretion	16	1.932141	0.0159016	0.0102626
GO:0051101	regulation of DNA binding	106	1.931130	0.0159016	0.0102626
GO:0051567	histone H3-K9 methylation	35	1.930734	0.0159016	0.0102626
GO:0045655	regulation of monocyte differentiation	16	1.930230	0.0159016	0.0102626
GO:0032743	positive regulation of interleukin-2 production	27	1.929536	0.0159016	0.0102626
GO:1901213	regulation of transcription from RNA polymerase II promoter involved in heart development	12	1.929135	0.0159016	0.0102626
GO:0030216	keratinocyte differentiation	112	1.927246	0.0159016	0.0102626
GO:0150076	neuroinflammatory response	54	1.926403	0.0159016	0.0102626
GO:0010528	regulation of transposition	18	1.926016	0.0159016	0.0102626
GO:0010529	negative regulation of transposition	18	1.926016	0.0159016	0.0102626
GO:0032760	positive regulation of tumor necrosis factor production	63	1.925842	0.0159016	0.0102626
GO:0045577	regulation of B cell differentiation	24	1.925295	0.0159016	0.0102626
GO:0045651	positive regulation of macrophage differentiation	13	1.922123	0.0159016	0.0102626
GO:0050855	regulation of B cell receptor signaling pathway	20	1.921984	0.0159016	0.0102626
GO:0042088	T-helper 1 type immune response	34	1.920935	0.0159016	0.0102626
GO:0003231	cardiac ventricle development	112	1.919741	0.0159016	0.0102626
GO:2000052	positive regulation of non-canonical Wnt signaling pathway	12	1.919267	0.0159016	0.0102626
GO:0032722	positive regulation of chemokine production	46	1.919169	0.0159016	0.0102626
GO:0060759	regulation of response to cytokine stimulus	154	1.918880	0.0159016	0.0102626
GO:0061900	glial cell activation	44	1.918561	0.0159016	0.0102626
GO:0000768	syncytium formation by plasma membrane fusion	41	1.918345	0.0159016	0.0102626
GO:0140253	cell-cell fusion	41	1.918345	0.0159016	0.0102626
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	87	1.914418	0.0159016	0.0102626
GO:1901222	regulation of NIK/NF-kappaB signaling	93	1.912684	0.0159016	0.0102626
GO:0030278	regulation of ossification	169	1.911704	0.0159016	0.0102626
GO:0001959	regulation of cytokine-mediated signaling pathway	143	1.909492	0.0159016	0.0102626
GO:0002688	regulation of leukocyte chemotaxis	89	1.908966	0.0159016	0.0102626
GO:0001771	immunological synapse formation	11	1.908597	0.0162534	0.0104897
GO:0006338	chromatin remodeling	145	1.907939	0.0159016	0.0102626
GO:1990868	response to chemokine	47	1.907536	0.0159016	0.0102626
GO:1990869	cellular response to chemokine	47	1.907536	0.0159016	0.0102626
GO:0003281	ventricular septum development	68	1.906723	0.0159016	0.0102626
GO:0030335	positive regulation of cell migration	427	1.906160	0.0159016	0.0102626
GO:0098727	maintenance of cell number	142	1.904374	0.0159016	0.0102626
GO:0060395	SMAD protein signal transduction	47	1.904358	0.0159016	0.0102626
GO:0001503	ossification	339	1.904357	0.0159016	0.0102626
GO:0042108	positive regulation of cytokine biosynthetic process	51	1.904243	0.0159016	0.0102626
GO:2000147	positive regulation of cell motility	442	1.902984	0.0159016	0.0102626
GO:0040029	regulation of gene expression, epigenetic	283	1.902963	0.0159016	0.0102626
GO:0006949	syncytium formation	42	1.902869	0.0159016	0.0102626
GO:0045591	positive regulation of regulatory T cell differentiation	12	1.902219	0.0159016	0.0102626
GO:0045576	mast cell activation	52	1.900166	0.0159016	0.0102626
GO:0033627	cell adhesion mediated by integrin	57	1.898605	0.0159016	0.0102626
GO:0002825	regulation of T-helper 1 type immune response	18	1.897308	0.0159016	0.0102626
GO:0002685	regulation of leukocyte migration	157	1.895378	0.0159016	0.0102626
GO:0002709	regulation of T cell mediated immunity	53	1.895353	0.0159016	0.0102626
GO:0032494	response to peptidoglycan	11	1.894001	0.0203686	0.0131455
GO:0072539	T-helper 17 cell differentiation	18	1.893888	0.0159016	0.0102626
GO:0010463	mesenchymal cell proliferation	41	1.893831	0.0159016	0.0102626
GO:0090197	positive regulation of chemokine secretion	13	1.891444	0.0159016	0.0102626
GO:0014841	skeletal muscle satellite cell proliferation	13	1.891213	0.0159016	0.0102626
GO:0032611	interleukin-1 beta production	71	1.889475	0.0159016	0.0102626
GO:0071103	DNA conformation change	253	1.889396	0.0159016	0.0102626
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	16	1.888025	0.0159016	0.0102626
GO:0043297	apical junction assembly	55	1.885889	0.0159016	0.0102626
GO:2001028	positive regulation of endothelial cell chemotaxis	14	1.885876	0.0159016	0.0102626
GO:0036499	PERK-mediated unfolded protein response	20	1.885593	0.0159016	0.0102626
GO:0061647	histone H3-K9 modification	45	1.884986	0.0159016	0.0102626
GO:0032732	positive regulation of interleukin-1 production	40	1.884932	0.0159016	0.0102626
GO:2000351	regulation of endothelial cell apoptotic process	36	1.884912	0.0159016	0.0102626
GO:0001782	B cell homeostasis	26	1.884167	0.0159016	0.0102626
GO:0019827	stem cell population maintenance	140	1.883757	0.0159016	0.0102626
GO:0034446	substrate adhesion-dependent cell spreading	82	1.882150	0.0159016	0.0102626
GO:0071677	positive regulation of mononuclear cell migration	19	1.882003	0.0159016	0.0102626
GO:0032200	telomere organization	158	1.879343	0.0159016	0.0102626
GO:0033003	regulation of mast cell activation	36	1.877610	0.0159016	0.0102626
GO:0045667	regulation of osteoblast differentiation	107	1.876388	0.0159016	0.0102626
GO:0050871	positive regulation of B cell activation	59	1.876015	0.0159016	0.0102626
GO:0033002	muscle cell proliferation	175	1.875741	0.0159016	0.0102626
GO:0032612	interleukin-1 production	80	1.874850	0.0159016	0.0102626
GO:0002711	positive regulation of T cell mediated immunity	33	1.874776	0.0159016	0.0102626
GO:0045765	regulation of angiogenesis	246	1.874682	0.0159016	0.0102626
GO:0002526	acute inflammatory response	111	1.873877	0.0159016	0.0102626
GO:0002820	negative regulation of adaptive immune response	38	1.872689	0.0159016	0.0102626
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	14	1.871924	0.0159016	0.0102626
GO:0032196	transposition	21	1.868497	0.0159016	0.0102626
GO:0043535	regulation of blood vessel endothelial cell migration	83	1.868467	0.0159016	0.0102626
GO:0045669	positive regulation of osteoblast differentiation	61	1.868142	0.0159016	0.0102626
GO:0050706	regulation of interleukin-1 beta secretion	35	1.867738	0.0159016	0.0102626
GO:0003401	axis elongation	25	1.866647	0.0159016	0.0102626
GO:0007249	I-kappaB kinase/NF-kappaB signaling	231	1.865616	0.0159016	0.0102626
GO:0002224	toll-like receptor signaling pathway	126	1.864033	0.0159016	0.0102626
GO:0048844	artery morphogenesis	58	1.863530	0.0159016	0.0102626
GO:0001819	positive regulation of cytokine production	364	1.863384	0.0159016	0.0102626
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	20	1.862362	0.0159016	0.0102626
GO:0032490	detection of molecule of bacterial origin	10	1.862120	0.0204307	0.0131856
GO:0032633	interleukin-4 production	25	1.862024	0.0159016	0.0102626
GO:0060561	apoptotic process involved in morphogenesis	21	1.861257	0.0159016	0.0102626
GO:0072376	protein activation cascade	58	1.860262	0.0159016	0.0102626
GO:0001776	leukocyte homeostasis	74	1.859524	0.0159016	0.0102626
GO:0072073	kidney epithelium development	120	1.858270	0.0159016	0.0102626
GO:0002643	regulation of tolerance induction	12	1.858143	0.0197595	0.0127525
GO:0032835	glomerulus development	52	1.858010	0.0159016	0.0102626
GO:0032103	positive regulation of response to external stimulus	251	1.856278	0.0159016	0.0102626
GO:0045342	MHC class II biosynthetic process	11	1.855797	0.0273893	0.0176766
GO:2000778	positive regulation of interleukin-6 secretion	23	1.855353	0.0159016	0.0102626
GO:0030888	regulation of B cell proliferation	49	1.854950	0.0159016	0.0102626
GO:0003179	heart valve morphogenesis	46	1.854925	0.0159016	0.0102626
GO:0060415	muscle tissue morphogenesis	58	1.854238	0.0159016	0.0102626
GO:0050921	positive regulation of chemotaxis	114	1.853568	0.0159016	0.0102626
GO:0002221	pattern recognition receptor signaling pathway	168	1.852932	0.0159016	0.0102626
GO:0032239	regulation of nucleobase-containing compound transport	13	1.852647	0.0265576	0.0171398
GO:0071674	mononuclear cell migration	54	1.848777	0.0159016	0.0102626
GO:0042100	B cell proliferation	57	1.848374	0.0159016	0.0102626
GO:0001892	embryonic placenta development	78	1.846747	0.0159016	0.0102626
GO:0045600	positive regulation of fat cell differentiation	55	1.846010	0.0159016	0.0102626
GO:0032731	positive regulation of interleukin-1 beta production	36	1.845689	0.0159016	0.0102626
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	44	1.845314	0.0159016	0.0102626
GO:0060602	branch elongation of an epithelium	17	1.844510	0.0159016	0.0102626
GO:0072538	T-helper 17 type immune response	20	1.844498	0.0159016	0.0102626
GO:1903209	positive regulation of oxidative stress-induced cell death	13	1.844202	0.0320996	0.0207165
GO:0043534	blood vessel endothelial cell migration	107	1.843567	0.0159016	0.0102626
GO:0055008	cardiac muscle tissue morphogenesis	50	1.842807	0.0159016	0.0102626
GO:0051272	positive regulation of cellular component movement	455	1.842325	0.0159016	0.0102626
GO:0032635	interleukin-6 production	114	1.842206	0.0159016	0.0102626
GO:0002827	positive regulation of T-helper 1 type immune response	12	1.841313	0.0265900	0.0171607
GO:0097028	dendritic cell differentiation	34	1.840625	0.0159016	0.0102626
GO:2000345	regulation of hepatocyte proliferation	12	1.840346	0.0265900	0.0171607
GO:1900409	positive regulation of cellular response to oxidative stress	14	1.839527	0.0197048	0.0127172
GO:0090025	regulation of monocyte chemotaxis	22	1.838861	0.0159016	0.0102626
GO:0062033	positive regulation of mitotic sister chromatid segregation	12	1.838753	0.0265900	0.0171607
GO:0003203	endocardial cushion morphogenesis	32	1.838738	0.0159016	0.0102626
GO:0048745	smooth muscle tissue development	17	1.838502	0.0159016	0.0102626
GO:0035850	epithelial cell differentiation involved in kidney development	39	1.838298	0.0159016	0.0102626
GO:0050856	regulation of T cell receptor signaling pathway	33	1.837707	0.0159016	0.0102626
GO:0050701	interleukin-1 secretion	46	1.837602	0.0159016	0.0102626
GO:0043536	positive regulation of blood vessel endothelial cell migration	53	1.837136	0.0159016	0.0102626
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	204	1.837084	0.0159016	0.0102626
GO:0014856	skeletal muscle cell proliferation	14	1.836477	0.0197048	0.0127172
GO:0032642	regulation of chemokine production	65	1.836350	0.0159016	0.0102626
GO:1901798	positive regulation of signal transduction by p53 class mediator	19	1.834798	0.0159016	0.0102626
GO:0007501	mesodermal cell fate specification	11	1.834673	0.0273893	0.0176766
GO:0010324	membrane invagination	56	1.834297	0.0159016	0.0102626
GO:0072006	nephron development	121	1.834188	0.0159016	0.0102626
GO:0007517	muscle organ development	327	1.832733	0.0159016	0.0102626
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	32	1.832515	0.0159016	0.0102626
GO:0001885	endothelial cell development	53	1.831371	0.0159016	0.0102626
GO:0055010	ventricular cardiac muscle tissue morphogenesis	39	1.829912	0.0159016	0.0102626
GO:0030224	monocyte differentiation	31	1.829335	0.0159016	0.0102626
GO:1903131	mononuclear cell differentiation	31	1.829335	0.0159016	0.0102626
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	14	1.829280	0.0197048	0.0127172
GO:0046006	regulation of activated T cell proliferation	27	1.829036	0.0159016	0.0102626
GO:0043392	negative regulation of DNA binding	43	1.828329	0.0159016	0.0102626
GO:0033628	regulation of cell adhesion mediated by integrin	41	1.828047	0.0159016	0.0102626
GO:0003205	cardiac chamber development	148	1.826673	0.0159016	0.0102626
GO:0051570	regulation of histone H3-K9 methylation	22	1.826448	0.0197048	0.0127172
GO:0090594	inflammatory response to wounding	12	1.826228	0.0321942	0.0207776
GO:0050727	regulation of inflammatory response	299	1.825642	0.0159016	0.0102626
GO:0045165	cell fate commitment	173	1.825579	0.0159016	0.0102626
GO:0070613	regulation of protein processing	83	1.824910	0.0159016	0.0102626
GO:0001774	microglial cell activation	37	1.824135	0.0159016	0.0102626
GO:0002269	leukocyte activation involved in inflammatory response	37	1.824135	0.0159016	0.0102626
GO:0031060	regulation of histone methylation	58	1.824079	0.0159016	0.0102626
GO:0045063	T-helper 1 cell differentiation	16	1.823253	0.0159016	0.0102626
GO:0002456	T cell mediated immunity	79	1.821986	0.0159016	0.0102626
GO:0010837	regulation of keratinocyte proliferation	28	1.821786	0.0159016	0.0102626
GO:0045618	positive regulation of keratinocyte differentiation	13	1.821416	0.0375938	0.0242624
GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	37	1.819091	0.0159016	0.0102626
GO:0032755	positive regulation of interleukin-6 production	67	1.816677	0.0159016	0.0102626
GO:0043032	positive regulation of macrophage activation	24	1.815363	0.0264554	0.0170738
GO:0032373	positive regulation of sterol transport	20	1.815061	0.0159016	0.0102626
GO:0032376	positive regulation of cholesterol transport	20	1.815061	0.0159016	0.0102626
GO:0016571	histone methylation	119	1.814959	0.0159016	0.0102626
GO:0008544	epidermis development	242	1.814736	0.0159016	0.0102626
GO:0035313	wound healing, spreading of epidermal cells	14	1.814266	0.0265576	0.0171398
GO:0036037	CD8-positive, alpha-beta T cell activation	17	1.813591	0.0159016	0.0102626
GO:0034086	maintenance of sister chromatid cohesion	12	1.812161	0.0434232	0.0280246
GO:0034088	maintenance of mitotic sister chromatid cohesion	12	1.812161	0.0434232	0.0280246
GO:0072009	nephron epithelium development	90	1.810670	0.0159016	0.0102626
GO:0016458	gene silencing	227	1.809978	0.0159016	0.0102626
GO:1905521	regulation of macrophage migration	31	1.809713	0.0159016	0.0102626
GO:0097581	lamellipodium organization	71	1.808668	0.0159016	0.0102626
GO:0003206	cardiac chamber morphogenesis	108	1.808651	0.0159016	0.0102626
GO:0042226	interleukin-6 biosynthetic process	18	1.808337	0.0198333	0.0128001
GO:0034329	cell junction assembly	201	1.808048	0.0159016	0.0102626
GO:1901888	regulation of cell junction assembly	86	1.807964	0.0159016	0.0102626
GO:1904019	epithelial cell apoptotic process	81	1.807663	0.0159016	0.0102626
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	51	1.807237	0.0159016	0.0102626
GO:0032675	regulation of interleukin-6 production	106	1.806698	0.0159016	0.0102626
GO:0040017	positive regulation of locomotion	470	1.806416	0.0159016	0.0102626
GO:1903317	regulation of protein maturation	85	1.806376	0.0159016	0.0102626
GO:0070266	necroptotic process	33	1.805738	0.0159016	0.0102626
GO:0036119	response to platelet-derived growth factor	21	1.802855	0.0159016	0.0102626
GO:0061448	connective tissue development	202	1.801726	0.0159016	0.0102626
GO:0002756	MyD88-independent toll-like receptor signaling pathway	33	1.801717	0.0159016	0.0102626
GO:0042554	superoxide anion generation	29	1.801536	0.0159016	0.0102626
GO:0006909	phagocytosis	219	1.800905	0.0159016	0.0102626
GO:0033631	cell-cell adhesion mediated by integrin	14	1.800522	0.0320996	0.0207165
GO:0002260	lymphocyte homeostasis	52	1.799426	0.0159016	0.0102626
GO:0090169	regulation of spindle assembly	26	1.798345	0.0159016	0.0102626
GO:0030858	positive regulation of epithelial cell differentiation	49	1.798153	0.0159016	0.0102626
GO:0060537	muscle tissue development	323	1.795333	0.0159016	0.0102626
GO:0036342	post-anal tail morphogenesis	15	1.794048	0.0159016	0.0102626
GO:0060038	cardiac muscle cell proliferation	45	1.793642	0.0159016	0.0102626
GO:0072678	T cell migration	47	1.792363	0.0197048	0.0127172
GO:0043922	negative regulation by host of viral transcription	10	1.792066	0.0274543	0.0177185
GO:0090196	regulation of chemokine secretion	14	1.791961	0.0320996	0.0207165
GO:2000117	negative regulation of cysteine-type endopeptidase activity	76	1.791895	0.0159016	0.0102626
GO:0032649	regulation of interferon-gamma production	69	1.791683	0.0159016	0.0102626
GO:0051092	positive regulation of NF-kappaB transcription factor activity	138	1.791230	0.0159016	0.0102626
GO:0050718	positive regulation of interleukin-1 beta secretion	25	1.791179	0.0159016	0.0102626
GO:0061005	cell differentiation involved in kidney development	48	1.790834	0.0197048	0.0127172
GO:0097300	programmed necrotic cell death	37	1.790489	0.0159016	0.0102626
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	11	1.790206	0.0273893	0.0176766
GO:0001570	vasculogenesis	68	1.790056	0.0159016	0.0102626
GO:0003197	endocardial cushion development	39	1.789537	0.0197048	0.0127172
GO:0006957	complement activation, alternative pathway	10	1.788942	0.0274543	0.0177185
GO:0002228	natural killer cell mediated immunity	47	1.787778	0.0197048	0.0127172
GO:0009913	epidermal cell differentiation	153	1.786766	0.0159016	0.0102626
GO:0050663	cytokine secretion	178	1.786763	0.0159016	0.0102626
GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	19	1.786232	0.0197048	0.0127172
GO:0009048	dosage compensation by inactivation of X chromosome	14	1.784684	0.0375938	0.0242624
GO:0030889	negative regulation of B cell proliferation	14	1.783965	0.0375938	0.0242624
GO:0001906	cell killing	94	1.783955	0.0159016	0.0102626
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	31	1.782842	0.0197048	0.0127172
GO:1904738	vascular associated smooth muscle cell migration	21	1.782671	0.0159016	0.0102626
GO:1904752	regulation of vascular associated smooth muscle cell migration	21	1.782671	0.0159016	0.0102626
GO:0010759	positive regulation of macrophage chemotaxis	14	1.782527	0.0375938	0.0242624
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	51	1.782434	0.0159016	0.0102626
GO:0016444	somatic cell DNA recombination	51	1.782434	0.0159016	0.0102626
GO:0031663	lipopolysaccharide-mediated signaling pathway	50	1.782364	0.0159016	0.0102626
GO:0001910	regulation of leukocyte mediated cytotoxicity	48	1.782318	0.0197048	0.0127172
GO:0042267	natural killer cell mediated cytotoxicity	43	1.782111	0.0159016	0.0102626
GO:0001818	negative regulation of cytokine production	225	1.781499	0.0159016	0.0102626
GO:1904385	cellular response to angiotensin	22	1.781400	0.0197048	0.0127172
GO:0050673	epithelial cell proliferation	326	1.781044	0.0159016	0.0102626
GO:0002312	B cell activation involved in immune response	58	1.779864	0.0159016	0.0102626
GO:0014015	positive regulation of gliogenesis	69	1.779598	0.0159016	0.0102626
GO:0002687	positive regulation of leukocyte migration	104	1.779018	0.0159016	0.0102626
GO:0060043	regulation of cardiac muscle cell proliferation	35	1.778492	0.0159016	0.0102626
GO:0060993	kidney morphogenesis	81	1.778479	0.0159016	0.0102626
GO:0048339	paraxial mesoderm development	15	1.778448	0.0159016	0.0102626
GO:0048872	homeostasis of number of cells	212	1.777820	0.0159016	0.0102626
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	12	1.776545	0.0483532	0.0312063
GO:0048565	digestive tract development	106	1.776344	0.0159016	0.0102626
GO:0060669	embryonic placenta morphogenesis	23	1.775885	0.0197048	0.0127172
GO:0001780	neutrophil homeostasis	16	1.775843	0.0159016	0.0102626
GO:0002040	sprouting angiogenesis	100	1.774975	0.0159016	0.0102626
GO:0032652	regulation of interleukin-1 production	69	1.774452	0.0159016	0.0102626
GO:0060099	regulation of phagocytosis, engulfment	13	1.771086	0.0375938	0.0242624
GO:0050817	coagulation	278	1.770573	0.0159016	0.0102626
GO:0010464	regulation of mesenchymal cell proliferation	32	1.770290	0.0197048	0.0127172
GO:0051053	negative regulation of DNA metabolic process	119	1.770101	0.0159016	0.0102626
GO:0050729	positive regulation of inflammatory response	114	1.769475	0.0159016	0.0102626
GO:0090026	positive regulation of monocyte chemotaxis	15	1.769075	0.0264462	0.0170679
GO:0072001	renal system development	260	1.768404	0.0159016	0.0102626
GO:0061323	cell proliferation involved in heart morphogenesis	11	1.767924	0.0273893	0.0176766
GO:0061180	mammary gland epithelium development	59	1.767544	0.0159016	0.0102626
GO:0072028	nephron morphogenesis	66	1.767270	0.0159016	0.0102626
GO:0050716	positive regulation of interleukin-1 secretion	27	1.767115	0.0197048	0.0127172
GO:0071599	otic vesicle development	14	1.766572	0.0433215	0.0279589
GO:0045824	negative regulation of innate immune response	46	1.765943	0.0159016	0.0102626
GO:0050711	negative regulation of interleukin-1 secretion	12	1.765659	0.0483532	0.0312063
GO:0055123	digestive system development	115	1.765231	0.0159016	0.0102626
GO:2001198	regulation of dendritic cell differentiation	11	1.764433	0.0273893	0.0176766
GO:0001822	kidney development	245	1.764288	0.0159016	0.0102626
GO:0097529	myeloid leukocyte migration	136	1.764026	0.0159016	0.0102626
GO:2000106	regulation of leukocyte apoptotic process	65	1.763899	0.0159016	0.0102626
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	34	1.763889	0.0159016	0.0102626
GO:0002088	lens development in camera-type eye	58	1.763267	0.0159016	0.0102626
GO:0007596	blood coagulation	276	1.763032	0.0159016	0.0102626
GO:0002690	positive regulation of leukocyte chemotaxis	69	1.762997	0.0159016	0.0102626
GO:0002042	cell migration involved in sprouting angiogenesis	53	1.762668	0.0159016	0.0102626
GO:0045685	regulation of glial cell differentiation	71	1.762664	0.0159016	0.0102626
GO:0070231	T cell apoptotic process	36	1.762107	0.0197048	0.0127172
GO:0072080	nephron tubule development	77	1.761785	0.0159016	0.0102626
GO:0032963	collagen metabolic process	79	1.761651	0.0159016	0.0102626
GO:0036005	response to macrophage colony-stimulating factor	11	1.761452	0.0273893	0.0176766
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	11	1.761452	0.0273893	0.0176766
GO:0001501	skeletal system development	394	1.760832	0.0159016	0.0102626
GO:0018023	peptidyl-lysine trimethylation	40	1.760697	0.0197048	0.0127172
GO:0090084	negative regulation of inclusion body assembly	10	1.759677	0.0274543	0.0177185
GO:0072643	interferon-gamma secretion	13	1.759566	0.0375938	0.0242624
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	59	1.759054	0.0159016	0.0102626
GO:0043542	endothelial cell migration	187	1.758009	0.0159016	0.0102626
GO:0035855	megakaryocyte development	16	1.757791	0.0159016	0.0102626
GO:0001655	urogenital system development	286	1.757291	0.0159016	0.0102626
GO:0071385	cellular response to glucocorticoid stimulus	50	1.757098	0.0159016	0.0102626
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	24	1.756906	0.0264554	0.0170738
GO:0002377	immunoglobulin production	81	1.755560	0.0159016	0.0102626
GO:0002700	regulation of production of molecular mediator of immune response	113	1.755499	0.0159016	0.0102626
GO:0001657	ureteric bud development	87	1.755266	0.0159016	0.0102626
GO:0051984	positive regulation of chromosome segregation	23	1.755042	0.0264462	0.0170679
GO:0045346	regulation of MHC class II biosynthetic process	10	1.754483	0.0333001	0.0214913
GO:0060348	bone development	163	1.753287	0.0159016	0.0102626
GO:0034340	response to type I interferon	79	1.751717	0.0159016	0.0102626
GO:0045687	positive regulation of glial cell differentiation	45	1.751650	0.0159016	0.0102626
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	100	1.750987	0.0159016	0.0102626
GO:0071887	leukocyte apoptotic process	83	1.750973	0.0159016	0.0102626
GO:0007520	myoblast fusion	30	1.749631	0.0197048	0.0127172
GO:0071157	negative regulation of cell cycle arrest	20	1.749398	0.0197048	0.0127172
GO:0061326	renal tubule development	79	1.748423	0.0159016	0.0102626
GO:0061842	microtubule organizing center localization	24	1.748174	0.0264554	0.0170738
GO:0031589	cell-substrate adhesion	295	1.748047	0.0159016	0.0102626
GO:1901224	positive regulation of NIK/NF-kappaB signaling	65	1.746970	0.0159016	0.0102626
GO:0050704	regulation of interleukin-1 secretion	38	1.746791	0.0263057	0.0169772
GO:0007173	epidermal growth factor receptor signaling pathway	104	1.746629	0.0159016	0.0102626
GO:0098542	defense response to other organism	314	1.746327	0.0159016	0.0102626
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	12	1.746302	0.0483532	0.0312063
GO:0072088	nephron epithelium morphogenesis	64	1.746195	0.0159016	0.0102626
GO:0045598	regulation of fat cell differentiation	108	1.745709	0.0159016	0.0102626
GO:2000484	positive regulation of interleukin-8 secretion	12	1.744731	0.0483532	0.0312063
GO:0043409	negative regulation of MAPK cascade	146	1.744633	0.0159016	0.0102626
GO:0033077	T cell differentiation in thymus	60	1.744315	0.0159016	0.0102626
GO:0071559	response to transforming growth factor beta	213	1.743084	0.0159016	0.0102626
GO:0050678	regulation of epithelial cell proliferation	276	1.743006	0.0159016	0.0102626
GO:0032735	positive regulation of interleukin-12 production	23	1.742468	0.0264462	0.0170679
GO:0051216	cartilage development	151	1.742406	0.0159016	0.0102626
GO:0048010	vascular endothelial growth factor receptor signaling pathway	87	1.742333	0.0159016	0.0102626
GO:0045932	negative regulation of muscle contraction	21	1.741989	0.0264462	0.0170679
GO:0034770	histone H4-K20 methylation	10	1.741871	0.0391612	0.0252740
GO:0032651	regulation of interleukin-1 beta production	61	1.741727	0.0159016	0.0102626
GO:0019730	antimicrobial humoral response	44	1.741602	0.0197048	0.0127172
GO:0010573	vascular endothelial growth factor production	30	1.741538	0.0197048	0.0127172
GO:0014812	muscle cell migration	78	1.741504	0.0159016	0.0102626
GO:0002279	mast cell activation involved in immune response	43	1.741022	0.0197048	0.0127172
GO:1901739	regulation of myoblast fusion	15	1.740615	0.0319261	0.0206045
GO:0060412	ventricular septum morphogenesis	41	1.740595	0.0264462	0.0170679
GO:0043405	regulation of MAP kinase activity	293	1.738556	0.0159016	0.0102626
GO:0001823	mesonephros development	90	1.738153	0.0159016	0.0102626
GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	13	1.737840	0.0375938	0.0242624
GO:0050679	positive regulation of epithelial cell proliferation	159	1.736970	0.0159016	0.0102626
GO:1902884	positive regulation of response to oxidative stress	16	1.736459	0.0159016	0.0102626
GO:0032615	interleukin-12 production	41	1.736317	0.0264462	0.0170679
GO:0001649	osteoblast differentiation	193	1.735343	0.0159016	0.0102626
GO:0006482	protein demethylation	26	1.734219	0.0197048	0.0127172
GO:0008214	protein dealkylation	26	1.734219	0.0197048	0.0127172
GO:0051894	positive regulation of focal adhesion assembly	23	1.734171	0.0319261	0.0206045
GO:0010631	epithelial cell migration	256	1.733934	0.0159016	0.0102626
GO:0001909	leukocyte mediated cytotoxicity	74	1.733642	0.0194000	0.0125204
GO:0048738	cardiac muscle tissue development	173	1.733347	0.0159016	0.0102626
GO:0002828	regulation of type 2 immune response	24	1.732897	0.0264554	0.0170738
GO:0060485	mesenchyme development	210	1.732241	0.0159016	0.0102626
GO:0072163	mesonephric epithelium development	88	1.731744	0.0159016	0.0102626
GO:0072164	mesonephric tubule development	88	1.731744	0.0159016	0.0102626
GO:0007549	dosage compensation	16	1.731523	0.0159016	0.0102626
GO:0061333	renal tubule morphogenesis	66	1.731275	0.0159016	0.0102626
GO:0010574	regulation of vascular endothelial growth factor production	28	1.730542	0.0159016	0.0102626
GO:0009299	mRNA transcription	22	1.730517	0.0374799	0.0241889
GO:0032753	positive regulation of interleukin-4 production	19	1.729985	0.0197048	0.0127172
GO:0010818	T cell chemotaxis	17	1.729262	0.0197048	0.0127172
GO:0032964	collagen biosynthetic process	40	1.729016	0.0319128	0.0205960
GO:0097530	granulocyte migration	76	1.728509	0.0159016	0.0102626
GO:0090132	epithelium migration	257	1.728302	0.0159016	0.0102626
GO:0060479	lung cell differentiation	15	1.727852	0.0319261	0.0206045
GO:0072078	nephron tubule morphogenesis	62	1.727813	0.0159016	0.0102626
GO:0048705	skeletal system morphogenesis	160	1.727186	0.0159016	0.0102626
GO:0032655	regulation of interleukin-12 production	40	1.726788	0.0319128	0.0205960
GO:0043616	keratinocyte proliferation	36	1.726787	0.0263057	0.0169772
GO:0010819	regulation of T cell chemotaxis	11	1.725942	0.0331329	0.0213834
GO:0007599	hemostasis	280	1.725723	0.0159016	0.0102626
GO:2000810	regulation of bicellular tight junction assembly	20	1.725523	0.0263057	0.0169772
GO:0036120	cellular response to platelet-derived growth factor stimulus	20	1.724955	0.0263057	0.0169772
GO:0007252	I-kappaB phosphorylation	17	1.724637	0.0197048	0.0127172
GO:0030866	cortical actin cytoskeleton organization	29	1.724197	0.0319128	0.0205960
GO:0071900	regulation of protein serine/threonine kinase activity	433	1.723793	0.0159016	0.0102626
GO:0048024	regulation of mRNA splicing, via spliceosome	68	1.722403	0.0159016	0.0102626
GO:0032602	chemokine production	72	1.721751	0.0159016	0.0102626
GO:0002262	myeloid cell homeostasis	130	1.721577	0.0159016	0.0102626
GO:0007043	cell-cell junction assembly	88	1.721402	0.0159016	0.0102626
GO:0031341	regulation of cell killing	56	1.720943	0.0159016	0.0102626
GO:0032673	regulation of interleukin-4 production	22	1.720471	0.0374799	0.0241889
GO:0014706	striated muscle tissue development	310	1.720435	0.0159016	0.0102626
GO:0045058	T cell selection	33	1.720380	0.0197048	0.0127172
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	53	1.720286	0.0159016	0.0102626
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	17	1.720223	0.0197048	0.0127172
GO:0051409	response to nitrosative stress	10	1.720201	0.0448092	0.0289191
GO:0002369	T cell cytokine production	33	1.719814	0.0197048	0.0127172
GO:0090322	regulation of superoxide metabolic process	31	1.719692	0.0319128	0.0205960
GO:1903670	regulation of sprouting angiogenesis	63	1.719486	0.0159016	0.0102626
GO:0032495	response to muramyl dipeptide	19	1.719439	0.0197048	0.0127172
GO:0045408	regulation of interleukin-6 biosynthetic process	17	1.719167	0.0197048	0.0127172
GO:0007507	heart development	479	1.719142	0.0159016	0.0102626
GO:0007099	centriole replication	31	1.717945	0.0319128	0.0205960
GO:0035456	response to interferon-beta	23	1.717023	0.0319261	0.0206045
GO:0048598	embryonic morphogenesis	462	1.716917	0.0159016	0.0102626
GO:1903036	positive regulation of response to wounding	55	1.716504	0.0159016	0.0102626
GO:0090083	regulation of inclusion body assembly	15	1.716475	0.0319261	0.0206045
GO:0002724	regulation of T cell cytokine production	26	1.716460	0.0263057	0.0169772
GO:0071901	negative regulation of protein serine/threonine kinase activity	114	1.715957	0.0159016	0.0102626
GO:0002062	chondrocyte differentiation	86	1.715530	0.0159016	0.0102626
GO:0070988	demethylation	51	1.714830	0.0159016	0.0102626
GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	14	1.714713	0.0433215	0.0279589
GO:0043583	ear development	180	1.713264	0.0159016	0.0102626
GO:0030852	regulation of granulocyte differentiation	13	1.712574	0.0375938	0.0242624
GO:0061041	regulation of wound healing	113	1.712218	0.0159016	0.0102626
GO:1900402	regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter	11	1.710765	0.0331329	0.0213834
GO:0071706	tumor necrosis factor superfamily cytokine production	125	1.710714	0.0159016	0.0102626
GO:0050707	regulation of cytokine secretion	153	1.710422	0.0159016	0.0102626
GO:0010742	macrophage derived foam cell differentiation	28	1.710096	0.0197048	0.0127172
GO:0090077	foam cell differentiation	28	1.710096	0.0197048	0.0127172
GO:0030903	notochord development	15	1.710025	0.0319261	0.0206045
GO:0060713	labyrinthine layer morphogenesis	18	1.709459	0.0322532	0.0208156
GO:0150077	regulation of neuroinflammatory response	31	1.709284	0.0319128	0.0205960
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	39	1.708885	0.0319261	0.0206045
GO:0002208	somatic diversification of immunoglobulins involved in immune response	39	1.708885	0.0319261	0.0206045
GO:0045190	isotype switching	39	1.708885	0.0319261	0.0206045
GO:0003007	heart morphogenesis	213	1.708862	0.0159016	0.0102626
GO:0008156	negative regulation of DNA replication	31	1.708773	0.0319128	0.0205960
GO:0033006	regulation of mast cell activation involved in immune response	28	1.708755	0.0197048	0.0127172
GO:1902807	negative regulation of cell cycle G1/S phase transition	102	1.708707	0.0159016	0.0102626
GO:0035886	vascular smooth muscle cell differentiation	24	1.708602	0.0375938	0.0242624
GO:0002347	response to tumor cell	19	1.708432	0.0197048	0.0127172
GO:0003176	aortic valve development	28	1.707419	0.0197048	0.0127172
GO:0043407	negative regulation of MAP kinase activity	59	1.706592	0.0159016	0.0102626
GO:0072171	mesonephric tubule morphogenesis	57	1.706170	0.0159016	0.0102626
GO:0061138	morphogenesis of a branching epithelium	154	1.705484	0.0159016	0.0102626
GO:0002253	activation of immune response	482	1.705183	0.0159016	0.0102626
GO:0070373	negative regulation of ERK1 and ERK2 cascade	64	1.703926	0.0159016	0.0102626
GO:0034101	erythrocyte homeostasis	105	1.703652	0.0194000	0.0125204
GO:0071560	cellular response to transforming growth factor beta stimulus	207	1.703601	0.0159016	0.0102626
GO:0090130	tissue migration	262	1.703279	0.0159016	0.0102626
GO:0060065	uterus development	17	1.702878	0.0197048	0.0127172
GO:0042246	tissue regeneration	59	1.702226	0.0159016	0.0102626
GO:0002440	production of molecular mediator of immune response	159	1.702047	0.0159016	0.0102626
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	15	1.701218	0.0319261	0.0206045
GO:0003208	cardiac ventricle morphogenesis	57	1.700933	0.0159016	0.0102626
GO:0097067	cellular response to thyroid hormone stimulus	14	1.700658	0.0433215	0.0279589
GO:0042692	muscle cell differentiation	289	1.700639	0.0159016	0.0102626
GO:0070102	interleukin-6-mediated signaling pathway	19	1.699888	0.0197048	0.0127172
GO:0048762	mesenchymal cell differentiation	171	1.699817	0.0159016	0.0102626
GO:0001763	morphogenesis of a branching structure	167	1.699520	0.0159016	0.0102626
GO:0002455	humoral immune response mediated by circulating immunoglobulin	32	1.699296	0.0260810	0.0168322
GO:1901673	regulation of mitotic spindle assembly	19	1.699292	0.0197048	0.0127172
GO:0003180	aortic valve morphogenesis	24	1.699038	0.0375938	0.0242624
GO:0051225	spindle assembly	85	1.698416	0.0159016	0.0102626
GO:0060544	regulation of necroptotic process	17	1.697964	0.0197048	0.0127172
GO:2001251	negative regulation of chromosome organization	115	1.697737	0.0159016	0.0102626
GO:0033004	negative regulation of mast cell activation	11	1.697672	0.0389629	0.0251460
GO:0001656	metanephros development	74	1.697086	0.0194000	0.0125204
GO:1901186	positive regulation of ERBB signaling pathway	30	1.697002	0.0263057	0.0169772
GO:0007063	regulation of sister chromatid cohesion	21	1.696877	0.0319261	0.0206045
GO:0003230	cardiac atrium development	27	1.695940	0.0374799	0.0241889
GO:0010165	response to X-ray	26	1.695241	0.0319261	0.0206045
GO:0060562	epithelial tube morphogenesis	274	1.694943	0.0159016	0.0102626
GO:0007044	cell-substrate junction assembly	93	1.694481	0.0159016	0.0102626
GO:0016447	somatic recombination of immunoglobulin gene segments	41	1.693616	0.0319261	0.0206045
GO:0051148	negative regulation of muscle cell differentiation	52	1.693158	0.0159016	0.0102626
GO:0071354	cellular response to interleukin-6	33	1.692290	0.0197048	0.0127172
GO:0010594	regulation of endothelial cell migration	145	1.691870	0.0159016	0.0102626
GO:0030218	erythrocyte differentiation	99	1.691794	0.0159016	0.0102626
GO:0048771	tissue remodeling	133	1.691614	0.0193893	0.0125135
GO:0010656	negative regulation of muscle cell apoptotic process	33	1.691224	0.0197048	0.0127172
GO:0002834	regulation of response to tumor cell	11	1.690939	0.0496855	0.0320662
GO:0002837	regulation of immune response to tumor cell	11	1.690939	0.0496855	0.0320662
GO:0048708	astrocyte differentiation	71	1.690388	0.0193760	0.0125049
GO:0035924	cellular response to vascular endothelial growth factor stimulus	48	1.690231	0.0197048	0.0127172
GO:0043303	mast cell degranulation	41	1.690198	0.0319261	0.0206045
GO:0070265	necrotic cell death	45	1.689783	0.0197048	0.0127172
GO:0043433	negative regulation of DNA-binding transcription factor activity	144	1.689639	0.0193760	0.0125049
GO:0060390	regulation of SMAD protein signal transduction	22	1.689180	0.0374799	0.0241889
GO:0010259	multicellular organism aging	28	1.689171	0.0197048	0.0127172
GO:0033119	negative regulation of RNA splicing	24	1.688955	0.0375938	0.0242624
GO:2001224	positive regulation of neuron migration	14	1.688781	0.0433215	0.0279589
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	17	1.688635	0.0197048	0.0127172
GO:0043030	regulation of macrophage activation	51	1.687092	0.0159016	0.0102626
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	120	1.686601	0.0193760	0.0125049
GO:0043588	skin development	214	1.686000	0.0159016	0.0102626
GO:0045601	regulation of endothelial cell differentiation	26	1.685928	0.0319261	0.0206045
GO:0002532	production of molecular mediator involved in inflammatory response	56	1.685889	0.0159016	0.0102626
GO:0035729	cellular response to hepatocyte growth factor stimulus	15	1.685665	0.0375213	0.0242156
GO:2000178	negative regulation of neural precursor cell proliferation	23	1.684850	0.0375402	0.0242278
GO:1901223	negative regulation of NIK/NF-kappaB signaling	22	1.684626	0.0374799	0.0241889
GO:0060487	lung epithelial cell differentiation	14	1.684471	0.0433215	0.0279589
GO:0001569	branching involved in blood vessel morphogenesis	26	1.684022	0.0319261	0.0206045
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	28	1.683940	0.0197048	0.0127172
GO:0061383	trabecula morphogenesis	44	1.683233	0.0197048	0.0127172
GO:2000352	negative regulation of endothelial cell apoptotic process	20	1.683192	0.0319261	0.0206045
GO:0002698	negative regulation of immune effector process	99	1.682919	0.0159016	0.0102626
GO:0007266	Rho protein signal transduction	151	1.680327	0.0159016	0.0102626
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	176	1.679771	0.0159016	0.0102626
GO:0051090	regulation of DNA-binding transcription factor activity	377	1.679371	0.0159016	0.0102626
GO:0051642	centrosome localization	23	1.678593	0.0375402	0.0242278
GO:0042330	taxis	461	1.678522	0.0159016	0.0102626
GO:0003159	morphogenesis of an endothelium	18	1.676972	0.0322532	0.0208156
GO:0061154	endothelial tube morphogenesis	18	1.676972	0.0322532	0.0208156
GO:0007221	positive regulation of transcription of Notch receptor target	17	1.676867	0.0320537	0.0206869
GO:0007423	sensory organ development	449	1.676590	0.0159016	0.0102626
GO:0048839	inner ear development	158	1.676317	0.0159016	0.0102626
GO:2000116	regulation of cysteine-type endopeptidase activity	200	1.676160	0.0159016	0.0102626
GO:0060675	ureteric bud morphogenesis	56	1.674972	0.0197048	0.0127172
GO:0072089	stem cell proliferation	102	1.674636	0.0193760	0.0125049
GO:0006935	chemotaxis	459	1.674622	0.0159016	0.0102626
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	20	1.674356	0.0319261	0.0206045
GO:0030330	DNA damage response, signal transduction by p53 class mediator	101	1.674300	0.0193760	0.0125049
GO:0060443	mammary gland morphogenesis	39	1.673613	0.0374799	0.0241889
GO:1905314	semi-lunar valve development	33	1.673501	0.0319128	0.0205960
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	48	1.673466	0.0197048	0.0127172
GO:0021983	pituitary gland development	31	1.672560	0.0319128	0.0205960
GO:0010758	regulation of macrophage chemotaxis	20	1.672143	0.0319261	0.0206045
GO:0072577	endothelial cell apoptotic process	42	1.671673	0.0375402	0.0242278
GO:0007566	embryo implantation	43	1.670773	0.0263057	0.0169772
GO:0072673	lamellipodium morphogenesis	16	1.669202	0.0264462	0.0170679
GO:0045686	negative regulation of glial cell differentiation	22	1.668482	0.0431083	0.0278214
GO:0072111	cell proliferation involved in kidney development	16	1.667810	0.0264462	0.0170679
GO:0007160	cell-matrix adhesion	192	1.666823	0.0188136	0.0121420
GO:0010664	negative regulation of striated muscle cell apoptotic process	23	1.666762	0.0432170	0.0278915
GO:0002726	positive regulation of T cell cytokine production	17	1.665782	0.0320537	0.0206869
GO:0032928	regulation of superoxide anion generation	20	1.665736	0.0319261	0.0206045
GO:0034109	homotypic cell-cell adhesion	68	1.665514	0.0193760	0.0125049
GO:2000648	positive regulation of stem cell proliferation	33	1.664710	0.0319128	0.0205960
GO:0060541	respiratory system development	174	1.664124	0.0188683	0.0121773
GO:0043304	regulation of mast cell degranulation	26	1.663605	0.0374229	0.0241521
GO:0043300	regulation of leukocyte degranulation	42	1.662125	0.0375402	0.0242278
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	159	1.661090	0.0159016	0.0102626
GO:0014911	positive regulation of smooth muscle cell migration	37	1.660726	0.0372315	0.0240286
GO:0060008	Sertoli cell differentiation	18	1.660621	0.0378372	0.0244195
GO:0009952	anterior/posterior pattern specification	136	1.660144	0.0193760	0.0125049
GO:0042533	tumor necrosis factor biosynthetic process	21	1.659768	0.0319261	0.0206045
GO:0042534	regulation of tumor necrosis factor biosynthetic process	21	1.659768	0.0319261	0.0206045
GO:0098534	centriole assembly	33	1.659250	0.0319128	0.0205960
GO:0030323	respiratory tube development	156	1.658955	0.0159016	0.0102626
GO:0034405	response to fluid shear stress	33	1.658654	0.0319128	0.0205960
GO:0030316	osteoclast differentiation	78	1.657688	0.0193760	0.0125049
GO:0006303	double-strand break repair via nonhomologous end joining	77	1.657018	0.0193760	0.0125049
GO:0014910	regulation of smooth muscle cell migration	60	1.656277	0.0159016	0.0102626
GO:0060009	Sertoli cell development	14	1.656253	0.0433215	0.0279589
GO:0002448	mast cell mediated immunity	43	1.656121	0.0374229	0.0241521
GO:0061045	negative regulation of wound healing	58	1.655519	0.0159016	0.0102626
GO:0060216	definitive hemopoiesis	16	1.655259	0.0264462	0.0170679
GO:0061028	establishment of endothelial barrier	39	1.655028	0.0430890	0.0278089
GO:0043388	positive regulation of DNA binding	50	1.654902	0.0197048	0.0127172
GO:0048568	embryonic organ development	338	1.654659	0.0159016	0.0102626
GO:0051147	regulation of muscle cell differentiation	138	1.654647	0.0193760	0.0125049
GO:0032680	regulation of tumor necrosis factor production	117	1.654443	0.0193760	0.0125049
GO:0010717	regulation of epithelial to mesenchymal transition	77	1.653435	0.0193760	0.0125049
GO:0090303	positive regulation of wound healing	45	1.653093	0.0319261	0.0206045
GO:0032691	negative regulation of interleukin-1 beta production	21	1.652860	0.0319261	0.0206045
GO:0034330	cell junction organization	259	1.652797	0.0159016	0.0102626
GO:1902275	regulation of chromatin organization	154	1.652574	0.0193760	0.0125049
GO:0071800	podosome assembly	15	1.652446	0.0478749	0.0308976
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	70	1.652334	0.0306432	0.0197766
GO:0048525	negative regulation of viral process	80	1.652208	0.0193760	0.0125049
GO:0060914	heart formation	19	1.650946	0.0482102	0.0311141
GO:0032640	tumor necrosis factor production	121	1.650859	0.0193760	0.0125049
GO:0001837	epithelial to mesenchymal transition	121	1.649856	0.0193760	0.0125049
GO:0042276	error-prone translesion synthesis	18	1.649016	0.0378372	0.0244195
GO:0071621	granulocyte chemotaxis	64	1.648357	0.0159016	0.0102626
GO:0070098	chemokine-mediated signaling pathway	39	1.648338	0.0430890	0.0278089
GO:0046330	positive regulation of JNK cascade	107	1.648305	0.0193760	0.0125049
GO:0003209	cardiac atrium morphogenesis	22	1.647890	0.0478191	0.0308616
GO:2000142	regulation of DNA-templated transcription, initiation	26	1.647430	0.0429443	0.0277155
GO:0031532	actin cytoskeleton reorganization	82	1.647379	0.0193760	0.0125049
GO:0032570	response to progesterone	40	1.647047	0.0473358	0.0305497
GO:0010470	regulation of gastrulation	32	1.645978	0.0370796	0.0239305
GO:0010595	positive regulation of endothelial cell migration	95	1.645432	0.0193760	0.0125049
GO:0072012	glomerulus vasculature development	19	1.644769	0.0482102	0.0311141
GO:0071384	cellular response to corticosteroid stimulus	54	1.643561	0.0260810	0.0168322
GO:0034121	regulation of toll-like receptor signaling pathway	59	1.643399	0.0159016	0.0102626
GO:0045071	negative regulation of viral genome replication	50	1.641648	0.0264462	0.0170679
GO:0007179	transforming growth factor beta receptor signaling pathway	162	1.641158	0.0159016	0.0102626
GO:0002637	regulation of immunoglobulin production	50	1.639619	0.0264462	0.0170679
GO:0048754	branching morphogenesis of an epithelial tube	126	1.639309	0.0193760	0.0125049
GO:0031062	positive regulation of histone methylation	36	1.638810	0.0429443	0.0277155
GO:0060428	lung epithelium development	28	1.638555	0.0476773	0.0307701
GO:0120193	tight junction organization	51	1.637827	0.0263057	0.0169772
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	92	1.636756	0.0159016	0.0102626
GO:0045445	myoblast differentiation	70	1.636026	0.0306432	0.0197766
GO:1903034	regulation of response to wounding	140	1.634943	0.0193760	0.0125049
GO:0045830	positive regulation of isotype switching	21	1.634767	0.0375402	0.0242278
GO:0035728	response to hepatocyte growth factor	17	1.634492	0.0482102	0.0311141
GO:1904706	negative regulation of vascular smooth muscle cell proliferation	17	1.633855	0.0482102	0.0311141
GO:0150063	visual system development	307	1.633458	0.0159016	0.0102626
GO:0048880	sensory system development	308	1.633448	0.0159016	0.0102626
GO:1904888	cranial skeletal system development	56	1.633236	0.0261757	0.0168934
GO:0050878	regulation of body fluid levels	413	1.633143	0.0159016	0.0102626
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	24	1.633131	0.0482102	0.0311141
GO:0001667	ameboidal-type cell migration	333	1.633123	0.0159016	0.0102626
GO:0070371	ERK1 and ERK2 cascade	241	1.632785	0.0159016	0.0102626
GO:0045606	positive regulation of epidermal cell differentiation	19	1.632305	0.0482102	0.0311141
GO:0001658	branching involved in ureteric bud morphogenesis	51	1.631431	0.0263057	0.0169772
GO:0070830	bicellular tight junction assembly	47	1.630710	0.0197048	0.0127172
GO:0060337	type I interferon signaling pathway	75	1.630452	0.0193760	0.0125049
GO:0071357	cellular response to type I interferon	75	1.630452	0.0193760	0.0125049
GO:0060840	artery development	81	1.630166	0.0193760	0.0125049
GO:0002715	regulation of natural killer cell mediated immunity	31	1.628855	0.0372354	0.0240311
GO:0050715	positive regulation of cytokine secretion	103	1.628801	0.0193760	0.0125049
GO:0051146	striated muscle cell differentiation	212	1.628567	0.0159016	0.0102626
GO:0042789	mRNA transcription by RNA polymerase II	16	1.628472	0.0319261	0.0206045
GO:0001890	placenta development	131	1.627659	0.0193760	0.0125049
GO:0002886	regulation of myeloid leukocyte mediated immunity	49	1.626735	0.0319128	0.0205960
GO:2000177	regulation of neural precursor cell proliferation	78	1.624597	0.0193760	0.0125049
GO:0033673	negative regulation of kinase activity	214	1.624591	0.0159016	0.0102626
GO:0097191	extrinsic apoptotic signaling pathway	192	1.623581	0.0188136	0.0121420
GO:0038127	ERBB signaling pathway	125	1.622297	0.0193760	0.0125049
GO:1904894	positive regulation of STAT cascade	61	1.622054	0.0256715	0.0165680
GO:0030324	lung development	152	1.621762	0.0193760	0.0125049
GO:0002718	regulation of cytokine production involved in immune response	69	1.621591	0.0307259	0.0198300
GO:2000404	regulation of T cell migration	34	1.619174	0.0372354	0.0240311
GO:0042094	interleukin-2 biosynthetic process	19	1.618605	0.0482102	0.0311141
GO:0042307	positive regulation of protein import into nucleus	34	1.617661	0.0372354	0.0240311
GO:0014909	smooth muscle cell migration	66	1.616343	0.0194000	0.0125204
GO:0071902	positive regulation of protein serine/threonine kinase activity	297	1.615329	0.0159016	0.0102626
GO:2000353	positive regulation of endothelial cell apoptotic process	16	1.615307	0.0432170	0.0278915
GO:0042026	protein refolding	18	1.614373	0.0378372	0.0244195
GO:0030206	chondroitin sulfate biosynthetic process	25	1.614203	0.0480182	0.0309901
GO:0061437	renal system vasculature development	21	1.614113	0.0431968	0.0278785
GO:0061440	kidney vasculature development	21	1.614113	0.0431968	0.0278785
GO:0010001	glial cell differentiation	200	1.612794	0.0188136	0.0121420
GO:0051893	regulation of focal adhesion assembly	59	1.612649	0.0197048	0.0127172
GO:0090109	regulation of cell-substrate junction assembly	59	1.612649	0.0197048	0.0127172
GO:1903053	regulation of extracellular matrix organization	36	1.612020	0.0475746	0.0307038
GO:0060317	cardiac epithelial to mesenchymal transition	32	1.610616	0.0424757	0.0274131
GO:0002757	immune response-activating signal transduction	427	1.608768	0.0159016	0.0102626
GO:0060760	positive regulation of response to cytokine stimulus	53	1.608257	0.0197048	0.0127172
GO:0002702	positive regulation of production of molecular mediator of immune response	77	1.607586	0.0193760	0.0125049
GO:1901184	regulation of ERBB signaling pathway	83	1.606535	0.0193760	0.0125049
GO:0007140	male meiotic nuclear division	32	1.606502	0.0424757	0.0274131
GO:0014013	regulation of gliogenesis	111	1.605840	0.0193760	0.0125049
GO:0051568	histone H3-K4 methylation	46	1.604962	0.0476773	0.0307701
GO:0072091	regulation of stem cell proliferation	57	1.604658	0.0159016	0.0102626
GO:0006469	negative regulation of protein kinase activity	197	1.604334	0.0188136	0.0121420
GO:0010830	regulation of myotube differentiation	44	1.604328	0.0319261	0.0206045
GO:0032088	negative regulation of NF-kappaB transcription factor activity	76	1.604119	0.0193760	0.0125049
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	71	1.602707	0.0306432	0.0197766
GO:0045005	DNA-dependent DNA replication maintenance of fidelity	33	1.602378	0.0472826	0.0305154
GO:0031214	biomineral tissue development	127	1.601758	0.0193760	0.0125049
GO:0043406	positive regulation of MAP kinase activity	231	1.600961	0.0159016	0.0102626
GO:2000379	positive regulation of reactive oxygen species metabolic process	83	1.599147	0.0193760	0.0125049
GO:0010811	positive regulation of cell-substrate adhesion	98	1.598895	0.0247948	0.0160021
GO:0002764	immune response-regulating signaling pathway	456	1.598504	0.0159016	0.0102626
GO:0070372	regulation of ERK1 and ERK2 cascade	226	1.597478	0.0159016	0.0102626
GO:0048713	regulation of oligodendrocyte differentiation	38	1.596679	0.0474352	0.0306138
GO:0007062	sister chromatid cohesion	45	1.596322	0.0430890	0.0278089
GO:0002200	somatic diversification of immune receptors	58	1.594089	0.0197048	0.0127172
GO:0051154	negative regulation of striated muscle cell differentiation	34	1.593661	0.0473813	0.0305791
GO:0050684	regulation of mRNA processing	101	1.593209	0.0247948	0.0160021
GO:0014902	myotube differentiation	87	1.591942	0.0159016	0.0102626
GO:0043410	positive regulation of MAPK cascade	430	1.591917	0.0159016	0.0102626
GO:0090183	regulation of kidney development	46	1.589529	0.0476773	0.0307701
GO:0046427	positive regulation of JAK-STAT cascade	59	1.589181	0.0261514	0.0168776
GO:0060761	negative regulation of response to cytokine stimulus	53	1.588439	0.0370676	0.0239228
GO:0001654	eye development	303	1.588298	0.0159016	0.0102626
GO:0050922	negative regulation of chemotaxis	33	1.587057	0.0472826	0.0305154
GO:0070206	protein trimerization	47	1.586973	0.0429443	0.0277155
GO:0061035	regulation of cartilage development	57	1.586969	0.0197048	0.0127172
GO:0000018	regulation of DNA recombination	77	1.586472	0.0193760	0.0125049
GO:0120192	tight junction assembly	48	1.585657	0.0319128	0.0205960
GO:0051153	regulation of striated muscle cell differentiation	87	1.585066	0.0159016	0.0102626
GO:0032922	circadian regulation of gene expression	57	1.584912	0.0197048	0.0127172
GO:2000146	negative regulation of cell motility	238	1.584632	0.0159016	0.0102626
GO:0030336	negative regulation of cell migration	227	1.583821	0.0159016	0.0102626
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	32	1.582697	0.0472169	0.0304730
GO:0050710	negative regulation of cytokine secretion	53	1.582509	0.0424757	0.0274131
GO:0002639	positive regulation of immunoglobulin production	32	1.582412	0.0472169	0.0304730
GO:0045444	fat cell differentiation	192	1.581299	0.0188136	0.0121420
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	77	1.580286	0.0193760	0.0125049
GO:0045995	regulation of embryonic development	110	1.579517	0.0193760	0.0125049
GO:0018205	peptidyl-lysine modification	350	1.578856	0.0159016	0.0102626
GO:0006613	cotranslational protein targeting to membrane	95	1.578639	0.0247948	0.0160021
GO:0035148	tube formation	130	1.578060	0.0248321	0.0160262
GO:0045047	protein targeting to ER	97	1.578037	0.0306432	0.0197766
GO:0048661	positive regulation of smooth muscle cell proliferation	81	1.577414	0.0193760	0.0125049
GO:0034333	adherens junction assembly	88	1.577320	0.0159016	0.0102626
GO:0030859	polarized epithelial cell differentiation	18	1.577243	0.0378372	0.0244195
GO:0050918	positive chemotaxis	55	1.576506	0.0371184	0.0239556
GO:0033044	regulation of chromosome organization	290	1.576322	0.0159016	0.0102626
GO:1900024	regulation of substrate adhesion-dependent cell spreading	47	1.576038	0.0429443	0.0277155
GO:0090307	mitotic spindle assembly	49	1.574693	0.0426607	0.0275325
GO:0001961	positive regulation of cytokine-mediated signaling pathway	46	1.574445	0.0476773	0.0307701
GO:1905954	positive regulation of lipid localization	71	1.574266	0.0355565	0.0229475
GO:0007405	neuroblast proliferation	53	1.572657	0.0472169	0.0304730
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	276	1.571713	0.0159016	0.0102626
GO:0051271	negative regulation of cellular component movement	254	1.571128	0.0159016	0.0102626
GO:0030032	lamellipodium assembly	54	1.570900	0.0424757	0.0274131
GO:0001960	negative regulation of cytokine-mediated signaling pathway	49	1.570795	0.0426607	0.0275325
GO:1905952	regulation of lipid localization	115	1.570432	0.0193760	0.0125049
GO:0042770	signal transduction in response to DNA damage	124	1.569165	0.0247948	0.0160021
GO:0032970	regulation of actin filament-based process	307	1.566530	0.0159016	0.0102626
GO:0046718	viral entry into host cell	106	1.566444	0.0249569	0.0161068
GO:0048706	embryonic skeletal system development	86	1.563905	0.0247948	0.0160021
GO:0001708	cell fate specification	53	1.563160	0.0472169	0.0304730
GO:0030522	intracellular receptor signaling pathway	253	1.562617	0.0159016	0.0102626
GO:0042303	molting cycle	86	1.561371	0.0247948	0.0160021
GO:0042633	hair cycle	86	1.561371	0.0247948	0.0160021
GO:0051145	smooth muscle cell differentiation	54	1.560849	0.0472169	0.0304730
GO:0006801	superoxide metabolic process	57	1.560493	0.0370796	0.0239305
GO:0007264	small GTPase mediated signal transduction	449	1.560206	0.0159016	0.0102626
GO:0060021	roof of mouth development	80	1.560045	0.0247948	0.0160021
GO:0071622	regulation of granulocyte chemotaxis	34	1.559391	0.0473813	0.0305791
GO:0002367	cytokine production involved in immune response	85	1.558968	0.0247948	0.0160021
GO:0000726	non-recombinational repair	83	1.558966	0.0247249	0.0159570
GO:0007045	cell-substrate adherens junction assembly	79	1.557622	0.0247601	0.0159798
GO:0048041	focal adhesion assembly	79	1.557622	0.0247601	0.0159798
GO:0016569	covalent chromatin modification	403	1.555151	0.0159016	0.0102626
GO:0042063	gliogenesis	262	1.554680	0.0159016	0.0102626
GO:0045216	cell-cell junction organization	116	1.553463	0.0248321	0.0160262
GO:0060349	bone morphogenesis	75	1.552902	0.0248321	0.0160262
GO:0048704	embryonic skeletal system morphogenesis	62	1.552842	0.0368442	0.0237786
GO:0051983	regulation of chromosome segregation	85	1.552341	0.0247948	0.0160021
GO:0035023	regulation of Rho protein signal transduction	118	1.550478	0.0306432	0.0197766
GO:0061008	hepaticobiliary system development	120	1.549316	0.0247948	0.0160021
GO:0010632	regulation of epithelial cell migration	201	1.546296	0.0188226	0.0121478
GO:0051781	positive regulation of cell division	68	1.545734	0.0451956	0.0291685
GO:0042326	negative regulation of phosphorylation	396	1.545011	0.0159016	0.0102626
GO:0090288	negative regulation of cellular response to growth factor stimulus	123	1.543845	0.0193760	0.0125049
GO:1903035	negative regulation of response to wounding	71	1.542021	0.0355565	0.0229475
GO:0051056	regulation of small GTPase mediated signal transduction	305	1.540444	0.0159016	0.0102626
GO:0043507	positive regulation of JUN kinase activity	62	1.539523	0.0467119	0.0301470
GO:0016570	histone modification	392	1.538633	0.0159016	0.0102626
GO:0050818	regulation of coagulation	64	1.537981	0.0464996	0.0300100
GO:1902532	negative regulation of intracellular signal transduction	461	1.537920	0.0159016	0.0102626
GO:0048660	regulation of smooth muscle cell proliferation	125	1.537857	0.0352673	0.0227609
GO:0002431	Fc receptor mediated stimulatory signaling pathway	78	1.537543	0.0350445	0.0226171
GO:0050764	regulation of phagocytosis	75	1.534482	0.0248321	0.0160262
GO:0048545	response to steroid hormone	337	1.533894	0.0159016	0.0102626
GO:0040013	negative regulation of locomotion	265	1.533721	0.0188136	0.0121420
GO:0031056	regulation of histone modification	129	1.532957	0.0306432	0.0197766
GO:2001234	negative regulation of apoptotic signaling pathway	199	1.531848	0.0188136	0.0121420
GO:0045088	regulation of innate immune response	367	1.530379	0.0159016	0.0102626
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	103	1.528565	0.0248321	0.0160262
GO:0051091	positive regulation of DNA-binding transcription factor activity	233	1.528187	0.0159016	0.0102626
GO:0052548	regulation of endopeptidase activity	287	1.528158	0.0159016	0.0102626
GO:0007015	actin filament organization	299	1.528005	0.0159016	0.0102626
GO:0033045	regulation of sister chromatid segregation	65	1.527800	0.0456122	0.0294374
GO:0042476	odontogenesis	105	1.525454	0.0307538	0.0198480
GO:0043506	regulation of JUN kinase activity	75	1.525270	0.0355565	0.0229475
GO:0031099	regeneration	163	1.525078	0.0240307	0.0155090
GO:0030838	positive regulation of actin filament polymerization	73	1.524823	0.0450884	0.0290993
GO:0048659	smooth muscle cell proliferation	127	1.524026	0.0353581	0.0228195
GO:0052547	regulation of peptidase activity	311	1.523719	0.0185164	0.0119502
GO:0051384	response to glucocorticoid	119	1.523049	0.0306432	0.0197766
GO:0001889	liver development	117	1.520731	0.0306432	0.0197766
GO:0051262	protein tetramerization	157	1.519759	0.0300692	0.0194062
GO:0010951	negative regulation of endopeptidase activity	145	1.519574	0.0248321	0.0160262
GO:0042475	odontogenesis of dentin-containing tooth	69	1.517813	0.0453344	0.0292581
GO:0048608	reproductive structure development	354	1.516569	0.0159016	0.0102626
GO:0071260	cellular response to mechanical stimulus	69	1.514274	0.0453344	0.0292581
GO:0043901	negative regulation of multi-organism process	143	1.511554	0.0306432	0.0197766
GO:0001933	negative regulation of protein phosphorylation	363	1.510792	0.0159016	0.0102626
GO:0006606	protein import into nucleus	96	1.510361	0.0352673	0.0227609
GO:0048732	gland development	355	1.510302	0.0159016	0.0102626
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	116	1.509756	0.0355157	0.0229212
GO:0051302	regulation of cell division	140	1.508449	0.0306432	0.0197766
GO:0010810	regulation of cell-substrate adhesion	178	1.506937	0.0291339	0.0188025
GO:0048144	fibroblast proliferation	76	1.505964	0.0306432	0.0197766
GO:0007265	Ras protein signal transduction	314	1.503164	0.0185994	0.0120037
GO:0051052	regulation of DNA metabolic process	361	1.502831	0.0159016	0.0102626
GO:0072599	establishment of protein localization to endoplasmic reticulum	101	1.502448	0.0306432	0.0197766
GO:0006352	DNA-templated transcription, initiation	215	1.502219	0.0188136	0.0121420
GO:0001942	hair follicle development	72	1.501251	0.0495485	0.0319778
GO:0032102	negative regulation of response to external stimulus	258	1.499971	0.0188136	0.0121420
GO:0030260	entry into host cell	118	1.499378	0.0352673	0.0227609
GO:0044409	entry into host	118	1.499378	0.0352673	0.0227609
GO:0051806	entry into cell of other organism involved in symbiotic interaction	118	1.499378	0.0352673	0.0227609
GO:0051828	entry into other organism involved in symbiotic interaction	118	1.499378	0.0352673	0.0227609
GO:0032956	regulation of actin cytoskeleton organization	267	1.499080	0.0231200	0.0149212
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	130	1.498967	0.0404474	0.0261040
GO:0009612	response to mechanical stimulus	180	1.496244	0.0336129	0.0216932
GO:0046849	bone remodeling	71	1.494655	0.0495485	0.0319778
GO:0006479	protein methylation	156	1.494622	0.0301179	0.0194376
GO:0008213	protein alkylation	156	1.494622	0.0301179	0.0194376
GO:0000723	telomere maintenance	145	1.494499	0.0306432	0.0197766
GO:0007569	cell aging	99	1.493633	0.0401798	0.0259313
GO:0043010	camera-type eye development	263	1.493101	0.0187720	0.0121151
GO:0051348	negative regulation of transferase activity	241	1.492540	0.0233030	0.0150394
GO:0031334	positive regulation of protein complex assembly	212	1.492490	0.0188136	0.0121420
GO:2000045	regulation of G1/S transition of mitotic cell cycle	139	1.491819	0.0306432	0.0197766
GO:0070302	regulation of stress-activated protein kinase signaling cascade	188	1.491710	0.0289365	0.0186751
GO:0045860	positive regulation of protein kinase activity	456	1.490393	0.0159016	0.0102626
GO:0022404	molting cycle process	74	1.489680	0.0499031	0.0322066
GO:0022405	hair cycle process	74	1.489680	0.0499031	0.0322066
GO:0018108	peptidyl-tyrosine phosphorylation	297	1.484074	0.0186645	0.0120457
GO:0032526	response to retinoic acid	93	1.483506	0.0450431	0.0290700
GO:0035265	organ growth	138	1.482493	0.0306432	0.0197766
GO:0061458	reproductive system development	357	1.481139	0.0159016	0.0102626
GO:0072175	epithelial tube formation	117	1.480118	0.0447895	0.0289064
GO:0018212	peptidyl-tyrosine modification	300	1.480041	0.0185994	0.0120037
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	147	1.479343	0.0306432	0.0197766
GO:0010466	negative regulation of peptidase activity	152	1.479306	0.0350391	0.0226137
GO:0046328	regulation of JNK cascade	149	1.473598	0.0306432	0.0197766
GO:0032874	positive regulation of stress-activated MAPK cascade	129	1.472039	0.0493954	0.0318789
GO:0007389	pattern specification process	322	1.470523	0.0183551	0.0118461
GO:0046546	development of primary male sexual characteristics	113	1.469931	0.0493954	0.0318789
GO:0032872	regulation of stress-activated MAPK cascade	186	1.468648	0.0380555	0.0245604
GO:0031348	negative regulation of defense response	170	1.465406	0.0379636	0.0245011
GO:0051607	defense response to virus	189	1.465127	0.0286513	0.0184911
GO:0071407	cellular response to organic cyclic compound	489	1.464697	0.0159016	0.0102626
GO:0043087	regulation of GTPase activity	392	1.464144	0.0159016	0.0102626
GO:2001020	regulation of response to DNA damage stimulus	194	1.462309	0.0233030	0.0150394
GO:0061351	neural precursor cell proliferation	131	1.461875	0.0448487	0.0289446
GO:0033674	positive regulation of kinase activity	494	1.461655	0.0159016	0.0102626
GO:0007565	female pregnancy	159	1.459833	0.0297585	0.0192056
GO:0051897	positive regulation of protein kinase B signaling	133	1.459693	0.0406290	0.0262213
GO:0030168	platelet activation	131	1.459078	0.0448487	0.0289446
GO:0034332	adherens junction organization	129	1.458939	0.0493954	0.0318789
GO:0030879	mammary gland development	118	1.458833	0.0447454	0.0288779
GO:0043009	chordate embryonic development	496	1.458308	0.0159016	0.0102626
GO:0021915	neural tube development	141	1.454769	0.0306432	0.0197766
GO:0051028	mRNA transport	138	1.453037	0.0352673	0.0227609
GO:1902905	positive regulation of supramolecular fiber organization	169	1.451102	0.0431545	0.0278511
GO:0048562	embryonic organ morphogenesis	217	1.448161	0.0285672	0.0184368
GO:0110053	regulation of actin filament organization	208	1.447671	0.0286513	0.0184911
GO:1902806	regulation of cell cycle G1/S phase transition	152	1.443387	0.0350391	0.0226137
GO:0002009	morphogenesis of an epithelium	461	1.439933	0.0159016	0.0102626
GO:0031960	response to corticosteroid	135	1.438319	0.0451041	0.0291094
GO:0031349	positive regulation of defense response	415	1.436665	0.0180628	0.0116574
GO:0045936	negative regulation of phosphate metabolic process	498	1.435827	0.0159016	0.0102626
GO:0090596	sensory organ morphogenesis	207	1.434792	0.0329418	0.0212600
GO:0008154	actin polymerization or depolymerization	155	1.430854	0.0485015	0.0313020
GO:0071214	cellular response to abiotic stimulus	277	1.428203	0.0279137	0.0180150
GO:0104004	cellular response to environmental stimulus	277	1.428203	0.0279137	0.0180150
GO:0001701	in utero embryonic development	307	1.422623	0.0185164	0.0119502
GO:0000819	sister chromatid segregation	148	1.422302	0.0404532	0.0261078
GO:0016485	protein processing	184	1.422255	0.0472437	0.0304903
GO:0010563	negative regulation of phosphorus metabolic process	499	1.422064	0.0159016	0.0102626
GO:0043547	positive regulation of GTPase activity	322	1.418397	0.0223178	0.0144035
GO:0006302	double-strand break repair	200	1.417340	0.0427401	0.0275837
GO:2001233	regulation of apoptotic signaling pathway	360	1.414907	0.0268566	0.0173328
GO:0050851	antigen receptor-mediated signaling pathway	191	1.414319	0.0425678	0.0274725
GO:0002768	immune response-regulating cell surface receptor signaling pathway	312	1.413609	0.0185164	0.0119502
GO:2001242	regulation of intrinsic apoptotic signaling pathway	147	1.413431	0.0494462	0.0319117
GO:0051495	positive regulation of cytoskeleton organization	188	1.409979	0.0429443	0.0277155
GO:0002429	immune response-activating cell surface receptor signaling pathway	284	1.409151	0.0372315	0.0240286
GO:0003002	regionalization	248	1.387532	0.0374229	0.0241521
GO:0045089	positive regulation of innate immune response	311	1.376130	0.0226241	0.0146012
GO:0009615	response to virus	264	1.373906	0.0374799	0.0241889
GO:0051493	regulation of cytoskeleton organization	439	1.372295	0.0180490	0.0116485
GO:0008380	RNA splicing	386	1.368319	0.0220555	0.0142342
GO:1902903	regulation of supramolecular fiber organization	286	1.356384	0.0453344	0.0292581

Enriched terms for module #84AD00 (MTcor = -0.93)

ID	Description	setSize	NES	p.adjust	qvalues
GO:0042773	ATP synthesis coupled electron transport	88	2.828241	0.0223578	0.0162795
GO:0042775	mitochondrial ATP synthesis coupled electron transport	87	2.817455	0.0223578	0.0162795
GO:0022904	respiratory electron transport chain	104	2.814443	0.0223578	0.0162795
GO:0045333	cellular respiration	171	2.775592	0.0223578	0.0162795
GO:0007269	neurotransmitter secretion	142	2.677088	0.0223578	0.0162795
GO:0099643	signal release from synapse	143	2.668203	0.0223578	0.0162795
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	54	2.650402	0.0223578	0.0162795
GO:0006119	oxidative phosphorylation	128	2.646906	0.0223578	0.0162795
GO:0098693	regulation of synaptic vesicle cycle	105	2.623405	0.0223578	0.0162795
GO:0016079	synaptic vesicle exocytosis	99	2.593716	0.0223578	0.0162795
GO:0048489	synaptic vesicle transport	125	2.586872	0.0223578	0.0162795
GO:0097480	establishment of synaptic vesicle localization	125	2.586872	0.0223578	0.0162795
GO:0010257	NADH dehydrogenase complex assembly	64	2.584921	0.0223578	0.0162795
GO:0032981	mitochondrial respiratory chain complex I assembly	64	2.584921	0.0223578	0.0162795
GO:0097479	synaptic vesicle localization	135	2.570717	0.0223578	0.0162795
GO:0017156	calcium ion regulated exocytosis	124	2.566309	0.0223578	0.0162795
GO:0099003	vesicle-mediated transport in synapse	171	2.564606	0.0223578	0.0162795
GO:0099504	synaptic vesicle cycle	158	2.549670	0.0223578	0.0162795
GO:1902803	regulation of synaptic vesicle transport	75	2.547550	0.0223578	0.0162795
GO:0046928	regulation of neurotransmitter secretion	93	2.539251	0.0223578	0.0162795
GO:0006101	citrate metabolic process	28	2.524150	0.0223578	0.0162795
GO:0009060	aerobic respiration	66	2.510141	0.0223578	0.0162795
GO:0033108	mitochondrial respiratory chain complex assembly	87	2.503824	0.0223578	0.0162795
GO:1900449	regulation of glutamate receptor signaling pathway	54	2.497750	0.0223578	0.0162795
GO:0006099	tricarboxylic acid cycle	26	2.480137	0.0223578	0.0162795
GO:2000300	regulation of synaptic vesicle exocytosis	70	2.461367	0.0223578	0.0162795
GO:0015980	energy derivation by oxidation of organic compounds	251	2.446646	0.0223578	0.0162795
GO:0017158	regulation of calcium ion-dependent exocytosis	90	2.438766	0.0223578	0.0162795
GO:0072350	tricarboxylic acid metabolic process	31	2.428176	0.0223578	0.0162795
GO:0051588	regulation of neurotransmitter transport	124	2.406984	0.0223578	0.0162795
GO:0022900	electron transport chain	162	2.402303	0.0223578	0.0162795
GO:0006836	neurotransmitter transport	222	2.395609	0.0223578	0.0162795
GO:0007005	mitochondrion organization	452	2.363754	0.0223578	0.0162795
GO:2001257	regulation of cation channel activity	150	2.355495	0.0223578	0.0162795
GO:0048168	regulation of neuronal synaptic plasticity	46	2.347220	0.0223578	0.0162795
GO:0051648	vesicle localization	261	2.322752	0.0223578	0.0162795
GO:0051650	establishment of vesicle localization	245	2.317448	0.0223578	0.0162795
GO:0006335	DNA replication-dependent nucleosome assembly	32	2.315180	0.0223578	0.0162795
GO:0034723	DNA replication-dependent nucleosome organization	32	2.315180	0.0223578	0.0162795
GO:0099177	regulation of trans-synaptic signaling	375	2.288237	0.0223578	0.0162795
GO:0050804	modulation of chemical synaptic transmission	374	2.287089	0.0223578	0.0162795
GO:2000310	regulation of NMDA receptor activity	33	2.286404	0.0223578	0.0162795
GO:0032543	mitochondrial translation	124	2.280576	0.0223578	0.0162795
GO:1901524	regulation of mitophagy	17	2.273647	0.0223578	0.0162795
GO:0099601	regulation of neurotransmitter receptor activity	62	2.272499	0.0223578	0.0162795
GO:1902600	proton transmembrane transport	128	2.272480	0.0223578	0.0162795
GO:0006103	2-oxoglutarate metabolic process	14	2.256982	0.0223578	0.0162795
GO:0032412	regulation of ion transmembrane transporter activity	213	2.247505	0.0223578	0.0162795
GO:0036465	synaptic vesicle recycling	49	2.244697	0.0223578	0.0162795
GO:0006091	generation of precursor metabolites and energy	464	2.236065	0.0223578	0.0162795
GO:0070125	mitochondrial translational elongation	85	2.227963	0.0223578	0.0162795
GO:0022898	regulation of transmembrane transporter activity	220	2.223322	0.0223578	0.0162795
GO:0007007	inner mitochondrial membrane organization	37	2.221033	0.0223578	0.0162795
GO:0023061	signal release	380	2.215097	0.0223578	0.0162795
GO:0009126	purine nucleoside monophosphate metabolic process	304	2.211605	0.0223578	0.0162795
GO:0009167	purine ribonucleoside monophosphate metabolic process	303	2.205684	0.0223578	0.0162795
GO:0000422	autophagy of mitochondrion	55	2.204424	0.0223578	0.0162795
GO:0061726	mitochondrion disassembly	55	2.204424	0.0223578	0.0162795
GO:0015672	monovalent inorganic cation transport	407	2.197697	0.0223578	0.0162795
GO:0046034	ATP metabolic process	274	2.197151	0.0223578	0.0162795
GO:0070126	mitochondrial translational termination	87	2.197053	0.0223578	0.0162795
GO:0009161	ribonucleoside monophosphate metabolic process	316	2.182006	0.0223578	0.0162795
GO:0098877	neurotransmitter receptor transport to plasma membrane	12	2.177158	0.0223578	0.0162795
GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	12	2.177158	0.0223578	0.0162795
GO:0009205	purine ribonucleoside triphosphate metabolic process	300	2.176266	0.0223578	0.0162795
GO:0035640	exploration behavior	23	2.172891	0.0223578	0.0162795
GO:0009199	ribonucleoside triphosphate metabolic process	305	2.171970	0.0223578	0.0162795
GO:1903540	establishment of protein localization to postsynaptic membrane	13	2.168906	0.0223578	0.0162795
GO:0032409	regulation of transporter activity	231	2.164542	0.0223578	0.0162795
GO:0000423	mitophagy	21	2.160674	0.0223578	0.0162795
GO:0009144	purine nucleoside triphosphate metabolic process	307	2.160562	0.0223578	0.0162795
GO:0009123	nucleoside monophosphate metabolic process	332	2.153721	0.0223578	0.0162795
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	67	2.150552	0.0223578	0.0162795
GO:0042407	cristae formation	30	2.146410	0.0223578	0.0162795
GO:1903533	regulation of protein targeting	79	2.143354	0.0223578	0.0162795
GO:0000266	mitochondrial fission	30	2.139862	0.0223578	0.0162795
GO:0045653	negative regulation of megakaryocyte differentiation	17	2.137809	0.0223578	0.0162795
GO:0006734	NADH metabolic process	34	2.132332	0.0223578	0.0162795
GO:0009141	nucleoside triphosphate metabolic process	323	2.128344	0.0223578	0.0162795
GO:0032594	protein transport within lipid bilayer	20	2.121697	0.0223578	0.0162795
GO:0006415	translational termination	99	2.117017	0.0223578	0.0162795
GO:1903008	organelle disassembly	78	2.116569	0.0223578	0.0162795
GO:1903146	regulation of autophagy of mitochondrion	41	2.111945	0.0223578	0.0162795
GO:0072384	organelle transport along microtubule	71	2.104751	0.0223578	0.0162795
GO:0070585	protein localization to mitochondrion	123	2.104079	0.0223578	0.0162795
GO:0035418	protein localization to synapse	55	2.099575	0.0223578	0.0162795
GO:0007006	mitochondrial membrane organization	115	2.098256	0.0223578	0.0162795
GO:0007215	glutamate receptor signaling pathway	81	2.098103	0.0223578	0.0162795
GO:0098930	axonal transport	50	2.093806	0.0223578	0.0162795
GO:0006839	mitochondrial transport	215	2.088816	0.0223578	0.0162795
GO:1903421	regulation of synaptic vesicle recycling	24	2.087482	0.0223578	0.0162795
GO:0006626	protein targeting to mitochondrion	84	2.087343	0.0223578	0.0162795
GO:0006007	glucose catabolic process	33	2.084569	0.0223578	0.0162795
GO:0006735	NADH regeneration	26	2.079659	0.0223578	0.0162795
GO:0061621	canonical glycolysis	26	2.079659	0.0223578	0.0162795
GO:0061718	glucose catabolic process to pyruvate	26	2.079659	0.0223578	0.0162795
GO:0032400	melanosome localization	23	2.073243	0.0223578	0.0162795
GO:0072655	establishment of protein localization to mitochondrion	120	2.071044	0.0223578	0.0162795
GO:0050905	neuromuscular process	87	2.070235	0.0223578	0.0162795
GO:0001505	regulation of neurotransmitter levels	289	2.069485	0.0223578	0.0162795
GO:0016241	regulation of macroautophagy	161	2.068810	0.0223578	0.0162795
GO:0000338	protein deneddylation	10	2.067647	0.0223578	0.0162795
GO:0033238	regulation of cellular amine metabolic process	74	2.066447	0.0223578	0.0162795
GO:0099632	protein transport within plasma membrane	13	2.065506	0.0223578	0.0162795
GO:0099637	neurotransmitter receptor transport	13	2.065506	0.0223578	0.0162795
GO:0048167	regulation of synaptic plasticity	163	2.064887	0.0223578	0.0162795
GO:0048488	synaptic vesicle endocytosis	37	2.060549	0.0223578	0.0162795
GO:0140238	presynaptic endocytosis	37	2.060549	0.0223578	0.0162795
GO:0140053	mitochondrial gene expression	147	2.059212	0.0223578	0.0162795
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	37	2.055423	0.0223578	0.0162795
GO:0061615	glycolytic process through fructose-6-phosphate	27	2.039727	0.0223578	0.0162795
GO:0061620	glycolytic process through glucose-6-phosphate	27	2.039727	0.0223578	0.0162795
GO:1904062	regulation of cation transmembrane transport	283	2.033419	0.0223578	0.0162795
GO:0016082	synaptic vesicle priming	12	2.032477	0.0223578	0.0162795
GO:0051875	pigment granule localization	24	2.032323	0.0223578	0.0162795
GO:0006851	mitochondrial calcium ion transmembrane transport	25	2.032321	0.0223578	0.0162795
GO:2000311	regulation of AMPA receptor activity	18	2.031251	0.0223578	0.0162795
GO:0051705	multi-organism behavior	60	2.031153	0.0223578	0.0162795
GO:0010822	positive regulation of mitochondrion organization	113	2.021605	0.0223578	0.0162795
GO:0090140	regulation of mitochondrial fission	23	2.019707	0.0223578	0.0162795
GO:0009150	purine ribonucleotide metabolic process	471	2.013367	0.0223578	0.0162795
GO:0032402	melanosome transport	19	2.010979	0.0223578	0.0162795
GO:0035641	locomotory exploration behavior	12	2.010047	0.0223578	0.0162795
GO:0050884	neuromuscular process controlling posture	12	2.009172	0.0223578	0.0162795
GO:0034765	regulation of ion transmembrane transport	408	2.008212	0.0223578	0.0162795
GO:0009259	ribonucleotide metabolic process	485	2.008072	0.0223578	0.0162795
GO:2001259	positive regulation of cation channel activity	63	2.001511	0.0223578	0.0162795
GO:0048169	regulation of long-term neuronal synaptic plasticity	25	1.997028	0.0223578	0.0162795
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	17	1.996994	0.0322778	0.0235026
GO:0019646	aerobic electron transport chain	17	1.996994	0.0322778	0.0235026
GO:0006813	potassium ion transport	169	1.995549	0.0223578	0.0162795
GO:0016999	antibiotic metabolic process	106	1.987685	0.0223578	0.0162795
GO:0032401	establishment of melanosome localization	20	1.983706	0.0223578	0.0162795
GO:0047496	vesicle transport along microtubule	38	1.981060	0.0223578	0.0162795
GO:0048857	neural nucleus development	55	1.976708	0.0223578	0.0162795
GO:0051904	pigment granule transport	20	1.974316	0.0223578	0.0162795
GO:0051646	mitochondrion localization	41	1.968018	0.0223578	0.0162795
GO:0071333	cellular response to glucose stimulus	112	1.967897	0.0223578	0.0162795
GO:0006163	purine nucleotide metabolic process	493	1.966354	0.0223578	0.0162795
GO:0043039	tRNA aminoacylation	45	1.957513	0.0223578	0.0162795
GO:0070584	mitochondrion morphogenesis	20	1.955266	0.0223578	0.0162795
GO:0051932	synaptic transmission, GABAergic	36	1.953458	0.0223578	0.0162795
GO:0017157	regulation of exocytosis	181	1.951179	0.0223578	0.0162795
GO:0106027	neuron projection organization	83	1.947896	0.0223578	0.0162795
GO:1903861	positive regulation of dendrite extension	21	1.944171	0.0322778	0.0235026
GO:0008089	anterograde axonal transport	42	1.943317	0.0223578	0.0162795
GO:0071322	cellular response to carbohydrate stimulus	122	1.942160	0.0223578	0.0162795
GO:0010765	positive regulation of sodium ion transport	29	1.941056	0.0223578	0.0162795
GO:0010970	transport along microtubule	141	1.940548	0.0223578	0.0162795
GO:0099111	microtubule-based transport	141	1.940548	0.0223578	0.0162795
GO:0071326	cellular response to monosaccharide stimulus	114	1.939894	0.0223578	0.0162795
GO:0071331	cellular response to hexose stimulus	114	1.939894	0.0223578	0.0162795
GO:0051905	establishment of pigment granule localization	21	1.939555	0.0322778	0.0235026
GO:0043648	dicarboxylic acid metabolic process	81	1.939448	0.0223578	0.0162795
GO:1903859	regulation of dendrite extension	23	1.937957	0.0322778	0.0235026
GO:0099500	vesicle fusion to plasma membrane	10	1.936617	0.0223578	0.0162795
GO:0031111	negative regulation of microtubule polymerization or depolymerization	32	1.931813	0.0223578	0.0162795
GO:0016242	negative regulation of macroautophagy	32	1.929146	0.0223578	0.0162795
GO:0071804	cellular potassium ion transport	121	1.928829	0.0223578	0.0162795
GO:0071805	potassium ion transmembrane transport	121	1.928829	0.0223578	0.0162795
GO:0070129	regulation of mitochondrial translation	25	1.926568	0.0406563	0.0296032
GO:0060078	regulation of postsynaptic membrane potential	119	1.921361	0.0223578	0.0162795
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	47	1.920872	0.0223578	0.0162795
GO:0072583	clathrin-dependent endocytosis	37	1.919903	0.0223578	0.0162795
GO:0099132	ATP hydrolysis coupled cation transmembrane transport	52	1.918763	0.0223578	0.0162795
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	12	1.918033	0.0223578	0.0162795
GO:1903305	regulation of regulated secretory pathway	134	1.916798	0.0223578	0.0162795
GO:0006521	regulation of cellular amino acid metabolic process	56	1.916787	0.0223578	0.0162795
GO:0097120	receptor localization to synapse	35	1.916778	0.0223578	0.0162795
GO:0010821	regulation of mitochondrion organization	170	1.914481	0.0223578	0.0162795
GO:0042551	neuron maturation	42	1.907931	0.0223578	0.0162795
GO:0008088	axo-dendritic transport	60	1.905457	0.0223578	0.0162795
GO:0030705	cytoskeleton-dependent intracellular transport	152	1.905058	0.0223578	0.0162795
GO:0099518	vesicle cytoskeletal trafficking	43	1.903245	0.0223578	0.0162795
GO:0016236	macroautophagy	267	1.902817	0.0223578	0.0162795
GO:1903539	protein localization to postsynaptic membrane	27	1.899904	0.0223578	0.0162795
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	17	1.898958	0.0322778	0.0235026
GO:0070131	positive regulation of mitochondrial translation	17	1.898371	0.0322778	0.0235026
GO:0043950	positive regulation of cAMP-mediated signaling	19	1.896103	0.0412231	0.0300159
GO:0043038	amino acid activation	46	1.892211	0.0223578	0.0162795
GO:0099188	postsynaptic cytoskeleton organization	10	1.890066	0.0322778	0.0235026
GO:0090313	regulation of protein targeting to membrane	34	1.889918	0.0223578	0.0162795
GO:0006418	tRNA aminoacylation for protein translation	42	1.889703	0.0223578	0.0162795
GO:0061003	positive regulation of dendritic spine morphogenesis	20	1.889239	0.0409811	0.0298397
GO:0051656	establishment of organelle localization	426	1.885636	0.0223578	0.0162795
GO:0034762	regulation of transmembrane transport	475	1.884657	0.0223578	0.0162795
GO:0043624	cellular protein complex disassembly	189	1.880512	0.0223578	0.0162795
GO:0032414	positive regulation of ion transmembrane transporter activity	94	1.877641	0.0223578	0.0162795
GO:0050432	catecholamine secretion	36	1.876824	0.0223578	0.0162795
GO:0001963	synaptic transmission, dopaminergic	24	1.873459	0.0488308	0.0355553
GO:2000785	regulation of autophagosome assembly	32	1.872715	0.0322778	0.0235026
GO:0071871	response to epinephrine	15	1.872703	0.0409811	0.0298397
GO:0006414	translational elongation	122	1.872548	0.0223578	0.0162795
GO:0140029	exocytic process	61	1.871625	0.0223578	0.0162795
GO:0035637	multicellular organismal signaling	176	1.865403	0.0223578	0.0162795
GO:0048311	mitochondrion distribution	13	1.865114	0.0322778	0.0235026
GO:0048813	dendrite morphogenesis	130	1.861945	0.0223578	0.0162795
GO:0008637	apoptotic mitochondrial changes	110	1.861401	0.0223578	0.0162795
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	57	1.859820	0.0223578	0.0162795
GO:0014047	glutamate secretion	41	1.859517	0.0223578	0.0162795
GO:0097484	dendrite extension	32	1.858119	0.0322778	0.0235026
GO:0050808	synapse organization	378	1.857439	0.0223578	0.0162795
GO:0044106	cellular amine metabolic process	111	1.854721	0.0223578	0.0162795
GO:0060079	excitatory postsynaptic potential	88	1.853358	0.0223578	0.0162795
GO:0090314	positive regulation of protein targeting to membrane	29	1.852956	0.0322778	0.0235026
GO:0015991	ATP hydrolysis coupled proton transport	24	1.849629	0.0488308	0.0355553
GO:0060997	dendritic spine morphogenesis	55	1.848544	0.0223578	0.0162795
GO:0007612	learning	137	1.847873	0.0223578	0.0162795
GO:0042391	regulation of membrane potential	338	1.846104	0.0223578	0.0162795
GO:0008053	mitochondrial fusion	21	1.841318	0.0491806	0.0358101
GO:0099565	chemical synaptic transmission, postsynaptic	96	1.839139	0.0223578	0.0162795
GO:0021762	substantia nigra development	40	1.837172	0.0322778	0.0235026
GO:0001678	cellular glucose homeostasis	122	1.829115	0.0223578	0.0162795
GO:0051290	protein heterotetramerization	51	1.824872	0.0223578	0.0162795
GO:0038003	opioid receptor signaling pathway	11	1.823995	0.0223578	0.0162795
GO:0007416	synapse assembly	163	1.821593	0.0223578	0.0162795
GO:0090141	positive regulation of mitochondrial fission	14	1.820792	0.0486375	0.0354146
GO:0035864	response to potassium ion	12	1.820304	0.0493488	0.0359325
GO:0050433	regulation of catecholamine secretion	34	1.818383	0.0406563	0.0296032
GO:0006883	cellular sodium ion homeostasis	12	1.817844	0.0493488	0.0359325
GO:1901526	positive regulation of mitophagy	10	1.817454	0.0415419	0.0302480
GO:0030534	adult behavior	120	1.817174	0.0223578	0.0162795
GO:0018210	peptidyl-threonine modification	103	1.813500	0.0223578	0.0162795
GO:0061001	regulation of dendritic spine morphogenesis	42	1.811413	0.0223578	0.0162795
GO:0030072	peptide hormone secretion	204	1.808586	0.0223578	0.0162795
GO:0010644	cell communication by electrical coupling	29	1.806425	0.0483524	0.0352070
GO:0030073	insulin secretion	173	1.805960	0.0223578	0.0162795
GO:0035307	positive regulation of protein dephosphorylation	39	1.803262	0.0406563	0.0296032
GO:1990542	mitochondrial transmembrane transport	64	1.802349	0.0223578	0.0162795
GO:0051952	regulation of amine transport	63	1.801349	0.0223578	0.0162795
GO:0043524	negative regulation of neuron apoptotic process	129	1.799533	0.0322778	0.0235026
GO:0018107	peptidyl-threonine phosphorylation	95	1.793408	0.0223578	0.0162795
GO:1903214	regulation of protein targeting to mitochondrion	44	1.792350	0.0322778	0.0235026
GO:2000786	positive regulation of autophagosome assembly	11	1.792139	0.0322778	0.0235026
GO:0051937	catecholamine transport	48	1.790691	0.0223578	0.0162795
GO:0019320	hexose catabolic process	50	1.789735	0.0223578	0.0162795
GO:0050775	positive regulation of dendrite morphogenesis	35	1.786120	0.0322778	0.0235026
GO:0007611	learning or memory	229	1.781654	0.0223578	0.0162795
GO:0032411	positive regulation of transporter activity	102	1.778558	0.0223578	0.0162795
GO:0015800	acidic amino acid transport	60	1.773786	0.0223578	0.0162795
GO:1901019	regulation of calcium ion transmembrane transporter activity	80	1.772436	0.0223578	0.0162795
GO:0090199	regulation of release of cytochrome c from mitochondria	44	1.770651	0.0322778	0.0235026
GO:0008344	adult locomotory behavior	66	1.770444	0.0223578	0.0162795
GO:0061337	cardiac conduction	135	1.767448	0.0223578	0.0162795
GO:0097061	dendritic spine organization	75	1.766925	0.0223578	0.0162795
GO:0048667	cell morphogenesis involved in neuron differentiation	469	1.763595	0.0223578	0.0162795
GO:0019226	transmission of nerve impulse	46	1.756020	0.0223578	0.0162795
GO:0048814	regulation of dendrite morphogenesis	81	1.755244	0.0223578	0.0162795
GO:0000183	chromatin silencing at rDNA	39	1.752559	0.0406563	0.0296032
GO:0006006	glucose metabolic process	180	1.752368	0.0223578	0.0162795
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	90	1.752298	0.0223578	0.0162795
GO:0008306	associative learning	73	1.748468	0.0322778	0.0235026
GO:0046365	monosaccharide catabolic process	57	1.744426	0.0322778	0.0235026
GO:0009749	response to glucose	165	1.740851	0.0223578	0.0162795
GO:0016358	dendrite development	212	1.737918	0.0223578	0.0162795
GO:0007018	microtubule-based movement	215	1.733848	0.0223578	0.0162795
GO:0006520	cellular amino acid metabolic process	323	1.731993	0.0223578	0.0162795
GO:0009308	amine metabolic process	118	1.731877	0.0223578	0.0162795
GO:0060627	regulation of vesicle-mediated transport	443	1.728295	0.0223578	0.0162795
GO:0035306	positive regulation of dephosphorylation	51	1.726995	0.0322778	0.0235026
GO:0035304	regulation of protein dephosphorylation	125	1.722718	0.0322778	0.0235026
GO:0051963	regulation of synapse assembly	99	1.721303	0.0223578	0.0162795
GO:0050890	cognition	261	1.719962	0.0223578	0.0162795
GO:0035176	social behavior	46	1.719651	0.0223578	0.0162795
GO:0051703	intraspecies interaction between organisms	46	1.719651	0.0223578	0.0162795
GO:0001508	action potential	108	1.718387	0.0223578	0.0162795
GO:0015837	amine transport	66	1.709635	0.0406563	0.0296032
GO:1903747	regulation of establishment of protein localization to mitochondrion	70	1.706602	0.0322778	0.0235026
GO:0050885	neuromuscular process controlling balance	41	1.706275	0.0406563	0.0296032
GO:0032386	regulation of intracellular transport	384	1.698225	0.0223578	0.0162795
GO:0007626	locomotory behavior	171	1.697666	0.0223578	0.0162795
GO:0046717	acid secretion	91	1.694416	0.0223578	0.0162795
GO:1904427	positive regulation of calcium ion transmembrane transport	62	1.693830	0.0406563	0.0296032
GO:1901215	negative regulation of neuron death	181	1.688678	0.0223578	0.0162795
GO:0060999	positive regulation of dendritic spine development	41	1.687612	0.0406563	0.0296032
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	50	1.687056	0.0406563	0.0296032
GO:0099173	postsynapse organization	154	1.684717	0.0223578	0.0162795
GO:0051965	positive regulation of synapse assembly	62	1.683552	0.0481498	0.0350594
GO:0060996	dendritic spine development	93	1.682415	0.0406563	0.0296032
GO:1990138	neuron projection extension	141	1.681285	0.0322778	0.0235026
GO:0010975	regulation of neuron projection development	433	1.679506	0.0223578	0.0162795
GO:0032984	protein-containing complex disassembly	286	1.676087	0.0223578	0.0162795
GO:0007409	axonogenesis	364	1.674457	0.0223578	0.0162795
GO:0090276	regulation of peptide hormone secretion	167	1.674122	0.0223578	0.0162795
GO:0060359	response to ammonium ion	115	1.670481	0.0223578	0.0162795
GO:0043242	negative regulation of protein complex disassembly	58	1.669751	0.0406563	0.0296032
GO:0061564	axon development	403	1.669393	0.0223578	0.0162795
GO:0009746	response to hexose	170	1.667157	0.0223578	0.0162795
GO:0046390	ribose phosphate biosynthetic process	270	1.665120	0.0223578	0.0162795
GO:1905037	autophagosome organization	72	1.664485	0.0322778	0.0235026
GO:0050796	regulation of insulin secretion	147	1.663763	0.0223578	0.0162795
GO:0051261	protein depolymerization	88	1.663742	0.0322778	0.0235026
GO:1903779	regulation of cardiac conduction	65	1.662983	0.0406563	0.0296032
GO:0035249	synaptic transmission, glutamatergic	60	1.659985	0.0406563	0.0296032
GO:0009152	purine ribonucleotide biosynthetic process	253	1.658978	0.0223578	0.0162795
GO:0050806	positive regulation of synaptic transmission	138	1.654886	0.0322778	0.0235026
GO:0009260	ribonucleotide biosynthetic process	266	1.648019	0.0223578	0.0162795
GO:0009127	purine nucleoside monophosphate biosynthetic process	165	1.647936	0.0223578	0.0162795
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	165	1.647936	0.0223578	0.0162795
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	78	1.647492	0.0322778	0.0235026
GO:0010823	negative regulation of mitochondrion organization	51	1.647404	0.0406563	0.0296032
GO:0009743	response to carbohydrate	196	1.646944	0.0223578	0.0162795
GO:0006914	autophagy	455	1.646826	0.0223578	0.0162795
GO:0061919	process utilizing autophagic mechanism	455	1.646826	0.0223578	0.0162795
GO:0006826	iron ion transport	50	1.645785	0.0481498	0.0350594
GO:0002478	antigen processing and presentation of exogenous peptide antigen	162	1.642622	0.0223578	0.0162795
GO:0019884	antigen processing and presentation of exogenous antigen	164	1.642118	0.0223578	0.0162795
GO:0009156	ribonucleoside monophosphate biosynthetic process	178	1.640985	0.0223578	0.0162795
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	93	1.639894	0.0406563	0.0296032
GO:0031145	anaphase-promoting complex-dependent catabolic process	76	1.639840	0.0223578	0.0162795
GO:0070588	calcium ion transmembrane transport	265	1.638377	0.0223578	0.0162795
GO:0006164	purine nucleotide biosynthetic process	263	1.636370	0.0223578	0.0162795
GO:0007032	endosome organization	70	1.635396	0.0406563	0.0296032
GO:0032456	endocytic recycling	42	1.635125	0.0482200	0.0351106
GO:0009145	purine nucleoside triphosphate biosynthetic process	151	1.628637	0.0223578	0.0162795
GO:0010976	positive regulation of neuron projection development	249	1.628464	0.0223578	0.0162795
GO:0010506	regulation of autophagy	301	1.624676	0.0223578	0.0162795
GO:0022411	cellular component disassembly	454	1.624089	0.0223578	0.0162795
GO:0001836	release of cytochrome c from mitochondria	55	1.623500	0.0406563	0.0296032
GO:0034284	response to monosaccharide	174	1.621427	0.0223578	0.0162795
GO:0008016	regulation of heart contraction	215	1.621068	0.0223578	0.0162795
GO:0006865	amino acid transport	122	1.618646	0.0322778	0.0235026
GO:0060998	regulation of dendritic spine development	70	1.617898	0.0406563	0.0296032
GO:0050803	regulation of synapse structure or activity	211	1.617753	0.0223578	0.0162795
GO:0032272	negative regulation of protein polymerization	54	1.617000	0.0483524	0.0352070
GO:0035725	sodium ion transmembrane transport	92	1.610313	0.0406563	0.0296032
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	150	1.609436	0.0322778	0.0235026
GO:0043270	positive regulation of ion transport	237	1.608919	0.0223578	0.0162795
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	94	1.607915	0.0477472	0.0347664
GO:0048193	Golgi vesicle transport	290	1.607064	0.0223578	0.0162795
GO:0006814	sodium ion transport	160	1.605574	0.0223578	0.0162795
GO:0033157	regulation of intracellular protein transport	210	1.605225	0.0223578	0.0162795
GO:0042180	cellular ketone metabolic process	197	1.600646	0.0223578	0.0162795
GO:0043523	regulation of neuron apoptotic process	185	1.600244	0.0223578	0.0162795
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	74	1.599848	0.0406563	0.0296032
GO:0048588	developmental cell growth	194	1.596777	0.0223578	0.0162795
GO:1901880	negative regulation of protein depolymerization	52	1.596148	0.0479719	0.0349300
GO:0045921	positive regulation of exocytosis	77	1.595622	0.0406563	0.0296032
GO:0043687	post-translational protein modification	335	1.593346	0.0223578	0.0162795
GO:0009201	ribonucleoside triphosphate biosynthetic process	155	1.592022	0.0223578	0.0162795
GO:0009124	nucleoside monophosphate biosynthetic process	185	1.591763	0.0223578	0.0162795
GO:0086065	cell communication involved in cardiac conduction	53	1.589545	0.0481936	0.0350913
GO:0006754	ATP biosynthetic process	142	1.588961	0.0322778	0.0235026
GO:0072522	purine-containing compound biosynthetic process	273	1.588010	0.0223578	0.0162795
GO:0050770	regulation of axonogenesis	143	1.585651	0.0322778	0.0235026
GO:1905477	positive regulation of protein localization to membrane	111	1.584776	0.0322778	0.0235026
GO:0038095	Fc-epsilon receptor signaling pathway	106	1.584156	0.0474974	0.0345845
GO:1904064	positive regulation of cation transmembrane transport	126	1.582798	0.0322778	0.0235026
GO:0031333	negative regulation of protein complex assembly	115	1.577292	0.0322778	0.0235026
GO:0051402	neuron apoptotic process	211	1.572632	0.0223578	0.0162795
GO:0060047	heart contraction	239	1.569107	0.0223578	0.0162795
GO:0000209	protein polyubiquitination	279	1.566710	0.0223578	0.0162795
GO:0000086	G2/M transition of mitotic cell cycle	227	1.561001	0.0223578	0.0162795
GO:0019318	hexose metabolic process	213	1.560866	0.0223578	0.0162795
GO:0009142	nucleoside triphosphate biosynthetic process	166	1.560120	0.0322778	0.0235026
GO:1903827	regulation of cellular protein localization	478	1.551928	0.0223578	0.0162795
GO:0031109	microtubule polymerization or depolymerization	92	1.551384	0.0476670	0.0347079
GO:0006399	tRNA metabolic process	157	1.550574	0.0467707	0.0340553
GO:0016482	cytosolic transport	136	1.548533	0.0322778	0.0235026
GO:0010389	regulation of G2/M transition of mitotic cell cycle	175	1.545398	0.0322778	0.0235026
GO:0046879	hormone secretion	254	1.540837	0.0223578	0.0162795
GO:0050807	regulation of synapse organization	207	1.538865	0.0223578	0.0162795
GO:0051668	localization within membrane	120	1.535453	0.0468065	0.0340813
GO:0008277	regulation of G protein-coupled receptor signaling pathway	135	1.526512	0.0322778	0.0235026
GO:0009165	nucleotide biosynthetic process	340	1.523839	0.0223578	0.0162795
GO:0010769	regulation of cell morphogenesis involved in differentiation	250	1.523596	0.0223578	0.0162795
GO:1901293	nucleoside phosphate biosynthetic process	343	1.522242	0.0223578	0.0162795
GO:0045666	positive regulation of neuron differentiation	321	1.515355	0.0223578	0.0162795
GO:0010498	proteasomal protein catabolic process	369	1.511369	0.0223578	0.0162795
GO:0034767	positive regulation of ion transmembrane transport	137	1.508585	0.0322778	0.0235026
GO:0009914	hormone transport	263	1.503732	0.0223578	0.0162795
GO:1903169	regulation of calcium ion transmembrane transport	131	1.502357	0.0474585	0.0345561
GO:0035303	regulation of dephosphorylation	189	1.501302	0.0223578	0.0162795
GO:0050773	regulation of dendrite development	137	1.500003	0.0322778	0.0235026
GO:0005996	monosaccharide metabolic process	234	1.498350	0.0223578	0.0162795
GO:0048639	positive regulation of developmental growth	148	1.496156	0.0466491	0.0339667
GO:0046883	regulation of hormone secretion	215	1.492888	0.0322778	0.0235026
GO:0003015	heart process	248	1.484907	0.0223578	0.0162795
GO:0048002	antigen processing and presentation of peptide antigen	174	1.482991	0.0322778	0.0235026
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	316	1.478598	0.0223578	0.0162795
GO:0051494	negative regulation of cytoskeleton organization	116	1.476216	0.0474585	0.0345561
GO:0051186	cofactor metabolic process	489	1.469441	0.0223578	0.0162795
GO:0044839	cell cycle G2/M phase transition	246	1.467143	0.0223578	0.0162795
GO:0010959	regulation of metal ion transport	321	1.459582	0.0223578	0.0162795
GO:0006090	pyruvate metabolic process	137	1.456922	0.0475367	0.0346130
GO:1903522	regulation of blood circulation	251	1.452451	0.0322778	0.0235026
GO:0051258	protein polymerization	212	1.448075	0.0322778	0.0235026
GO:1990778	protein localization to cell periphery	260	1.445071	0.0322778	0.0235026
GO:0140056	organelle localization by membrane tethering	138	1.441590	0.0474585	0.0345561
GO:1902749	regulation of cell cycle G2/M phase transition	192	1.440348	0.0456751	0.0332576
GO:1903829	positive regulation of cellular protein localization	297	1.430599	0.0223578	0.0162795
GO:0034764	positive regulation of transmembrane transport	173	1.428905	0.0461894	0.0336321
GO:0031346	positive regulation of cell projection organization	334	1.426292	0.0223578	0.0162795
GO:0033500	carbohydrate homeostasis	188	1.417367	0.0453990	0.0330565
GO:0070997	neuron death	311	1.414492	0.0223578	0.0162795
GO:0019882	antigen processing and presentation	202	1.412522	0.0457074	0.0332811
GO:0018209	peptidyl-serine modification	232	1.410053	0.0459884	0.0334857
GO:0010256	endomembrane system organization	344	1.400693	0.0223578	0.0162795
GO:0016311	dephosphorylation	418	1.391967	0.0322778	0.0235026
GO:0010817	regulation of hormone levels	412	1.388222	0.0223578	0.0162795
GO:0070838	divalent metal ion transport	401	1.383133	0.0322778	0.0235026
GO:0072511	divalent inorganic cation transport	403	1.380272	0.0322778	0.0235026
GO:0006816	calcium ion transport	364	1.379089	0.0322778	0.0235026
GO:0032535	regulation of cellular component size	292	1.377722	0.0453990	0.0330565
GO:1901214	regulation of neuron death	279	1.372852	0.0453368	0.0330113
GO:0019941	modification-dependent protein catabolic process	472	1.368516	0.0443827	0.0323165
GO:0006511	ubiquitin-dependent protein catabolic process	467	1.360809	0.0450364	0.0327925
GO:0044282	small molecule catabolic process	363	1.350433	0.0322778	0.0235026
GO:0022604	regulation of cell morphogenesis	411	1.345709	0.0453061	0.0329889

rm(df)

Disease Gene Network

for(module in top_modules){
  df = enrichment_DGN[[module]] %>% dplyr::select(ID, Description, setSize, NES, p.adjust, qvalues) %>% arrange(desc(NES)) %>% filter(NES>0)
  if(nrow(df)>0){
    print(kable(df, caption = paste0('Enriched terms for module ', module, ' (MTcor = ', round(dataset$MTcor[dataset$Module==module][1],2),')')))
    cat('\n') 
  } else cat(paste0('\nNo enrichment found for module ',module,'\n'))
}

Enriched terms for module #00B9E3 (MTcor = -0.93)

ID	Description	setSize	NES	p.adjust	qvalues
umls:C0543888	Epileptic encephalopathy	51	2.517619	0.0466231	0.0349444
umls:C1838979	MITOCHONDRIAL COMPLEX I DEFICIENCY	29	2.409845	0.0466231	0.0349444
umls:C0751122	Infantile Severe Myoclonic Epilepsy	25	2.303187	0.0466231	0.0349444
umls:C0014547	Epilepsies, Partial	42	2.291802	0.0466231	0.0349444
umls:C0406810	Carney Complex	27	2.207425	0.0466231	0.0349444
umls:C0085292	Stiff-Person Syndrome	19	2.160874	0.0466231	0.0349444
umls:C0037769	West Syndrome	58	2.137014	0.0466231	0.0349444
umls:C0270850	Idiopathic generalized epilepsy	45	2.125396	0.0466231	0.0349444
umls:C0393706	Early infantile epileptic encephalopathy with suppression bursts	19	2.120049	0.0466231	0.0349444
umls:C2936907	NADH:Q(1) Oxidoreductase deficiency	20	2.097329	0.0466231	0.0349444
umls:C0014548	Epilepsy, Generalized	44	2.086088	0.0466231	0.0349444
umls:C0014550	Epilepsies, Myoclonic	36	2.079689	0.0466231	0.0349444
umls:C1955869	Malformations of Cortical Development	45	2.063900	0.0466231	0.0349444
umls:C2931919	X-linked infantile spasm syndrome	15	2.055925	0.0466231	0.0349444
umls:C0427086	Involuntary Movements	13	2.054965	0.0466231	0.0349444
umls:C0342776	Nicotinamide adenine dinucleotide coenzyme Q reductase deficiency	38	2.036608	0.0466231	0.0349444
umls:C0270736	Essential Tremor	49	2.033486	0.0466231	0.0349444
umls:C0238111	Lennox-Gastaut syndrome	11	2.028922	0.0466231	0.0349444
umls:C0026650	Movement Disorders	95	1.998762	0.0466231	0.0349444
umls:C0023264	Leigh Disease	77	1.985598	0.0466231	0.0349444
umls:C1838951	LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY	14	1.968265	0.0466231	0.0349444
umls:C1096063	Drug Resistant Epilepsy	53	1.958415	0.0466231	0.0349444
umls:C0162635	Angelman Syndrome	53	1.956889	0.0466231	0.0349444
umls:C0376532	Epilepsy, Rolandic	15	1.950209	0.0466231	0.0349444
umls:C1849156	Spastic Ataxia	14	1.947152	0.0466231	0.0349444
umls:C0004134	Ataxia	221	1.944100	0.0466231	0.0349444
umls:C0751214	Hyperalgesia, Thermal	24	1.942523	0.0466231	0.0349444
umls:C0234166	Hyperexplexia	10	1.916174	0.0466231	0.0349444
umls:C0014553	Absence Epilepsy	49	1.888701	0.0466231	0.0349444
umls:C0391957	idiopathic epilepsy	17	1.883950	0.0466231	0.0349444
umls:C0014556	Epilepsy, Temporal Lobe	175	1.873512	0.0466231	0.0349444
umls:C1306341	Mental handicap	20	1.857124	0.0482247	0.0361448
umls:C0525045	Mood Disorders	238	1.850502	0.0466231	0.0349444
umls:C0751495	Seizures, Focal	18	1.836239	0.0482247	0.0361448
umls:C0035372	Rett Syndrome	111	1.834904	0.0466231	0.0349444
umls:C1142166	Brugada Syndrome (disorder)	46	1.828296	0.0466231	0.0349444
umls:C1510586	Autism Spectrum Disorders	216	1.824252	0.0466231	0.0349444
umls:C1720189	Episodic Ataxia	18	1.816075	0.0482247	0.0361448
umls:C0278864	Growth Hormone-Producing Pituitary Gland Neoplasm	10	1.807948	0.0482247	0.0361448
umls:C0432028	Split foot	10	1.807657	0.0482247	0.0361448
umls:C2911647	Weight Gain Adverse Event	138	1.803999	0.0466231	0.0349444
umls:C0037773	Spastic Paraplegia, Hereditary	62	1.782308	0.0466231	0.0349444
umls:C0162670	Mitochondrial Myopathies	48	1.748064	0.0471197	0.0353166
umls:C0085584	Encephalopathies	120	1.734605	0.0466231	0.0349444
umls:C0242422	Parkinsonian Disorders	173	1.710886	0.0466231	0.0349444
umls:C1263846	Attention deficit hyperactivity disorder	365	1.705684	0.0466231	0.0349444
umls:C0004936	Mental disorders	384	1.687791	0.0466231	0.0349444
umls:C0424551	Impaired exercise tolerance	27	1.685058	0.0481819	0.0361127
umls:C0009952	Febrile Convulsions	60	1.660894	0.0495553	0.0371421
umls:C0236736	Cocaine-Related Disorders	93	1.641811	0.0466231	0.0349444
umls:C0393593	Dystonia Disorders	119	1.637567	0.0466231	0.0349444
umls:C0424605	Developmental delay (disorder)	170	1.617865	0.0466231	0.0349444
umls:C0007758	Cerebellar Ataxia	94	1.611195	0.0484409	0.0363069
umls:C3714756	Intellectual Disability	422	1.609837	0.0466231	0.0349444
umls:C0041696	Unipolar Depression	366	1.606141	0.0466231	0.0349444
umls:C0018817	Atrial Septal Defects	231	1.584548	0.0466231	0.0349444
umls:C0025362	Mental Retardation	356	1.573522	0.0466231	0.0349444
umls:C0027765	nervous system disorder	388	1.567742	0.0466231	0.0349444
umls:C1269683	Major Depressive Disorder	426	1.564966	0.0466231	0.0349444
umls:C0751651	Mitochondrial Diseases	123	1.537339	0.0484409	0.0363069
umls:C0338656	Impaired cognition	343	1.514572	0.0466231	0.0349444
umls:C0043094	Weight Gain	217	1.473246	0.0482247	0.0361448

Enriched terms for module #73B000 (MTcor = 0.94)

ID	Description	setSize	NES	p.adjust	qvalues
umls:C2986658	Diffuse Intrinsic Pontine Glioma	19	2.664576	0.0167243	0.0117021
umls:C0278504	Non-small cell lung cancer stage I	61	2.520511	0.0167243	0.0117021
umls:C0595936	Aqueous Humor Disorders	54	2.368952	0.0167243	0.0117021
umls:C0600518	Choroidal Neovascularization	43	2.332125	0.0167243	0.0117021
umls:C0016059	Fibrosis	163	2.305263	0.0167243	0.0117021
umls:C0034067	Pulmonary Emphysema	153	2.305145	0.0167243	0.0117021
umls:C1800706	Idiopathic Pulmonary Fibrosis	276	2.296737	0.0167243	0.0117021
umls:C3714514	Infection	464	2.287752	0.0167243	0.0117021
umls:C0240035	Interstitial fibrosis	82	2.270451	0.0167243	0.0117021
umls:C0151650	Renal fibrosis	143	2.268175	0.0167243	0.0117021
umls:C1306759	Eosinophilic disorder	96	2.258364	0.0167243	0.0117021
umls:C0152101	Hypoplastic Left Heart Syndrome	18	2.252855	0.0167243	0.0117021
umls:C0162871	Aortic Aneurysm, Abdominal	151	2.243151	0.0167243	0.0117021
umls:C1636667	Disorder characterized by eosinophilia	95	2.235024	0.0167243	0.0117021
umls:C0042798	Low Vision	19	2.233750	0.0167243	0.0117021
umls:C0041956	Ureteral obstruction	120	2.227728	0.0167243	0.0117021
umls:C0153676	Secondary malignant neoplasm of lung	490	2.218196	0.0167243	0.0117021
umls:C0002962	Angina Pectoris	31	2.217219	0.0167243	0.0117021
umls:C0340643	Dissection of aorta	31	2.201097	0.0167243	0.0117021
umls:C0019189	Hepatitis, Chronic	138	2.198963	0.0167243	0.0117021
umls:C0238288	Muscular Dystrophy, Facioscapulohumeral	60	2.196008	0.0167243	0.0117021
umls:C0025568	Metaplasia	62	2.193596	0.0167243	0.0117021
umls:C3495559	Juvenile arthritis	272	2.193496	0.0167243	0.0117021
umls:C0004623	Bacterial Infections	180	2.182155	0.0167243	0.0117021
umls:C3825567	Tumors in children	10	2.175738	0.0167243	0.0117021
umls:C0879615	Stromal Neoplasm	70	2.175153	0.0167243	0.0117021
umls:C0243038	Carcinoma, Lewis Lung	67	2.162927	0.0167243	0.0117021
umls:C1527311	Brain Edema	43	2.150425	0.0167243	0.0117021
umls:C0036421	Systemic Scleroderma	441	2.140162	0.0167243	0.0117021
umls:C1261287	Stenosis	26	2.136433	0.0167243	0.0117021
umls:C0008495	Chorioamnionitis	156	2.136288	0.0167243	0.0117021
umls:C0026654	Moyamoya Disease	34	2.133518	0.0167243	0.0117021
umls:C0015944	Fetal Membranes, Premature Rupture	155	2.129837	0.0167243	0.0117021
umls:C0027613	Neonatal hepatitis	12	2.110280	0.0167243	0.0117021
umls:C0029434	Osteogenesis Imperfecta	38	2.104095	0.0167243	0.0117021
umls:C0220810	Congenital defects	43	2.101958	0.0167243	0.0117021
umls:C0001339	Acute pancreatitis	70	2.099831	0.0167243	0.0117021
umls:C3665419	Intracranial glioma	34	2.098128	0.0167243	0.0117021
umls:C0003486	Aortic Aneurysm	167	2.097108	0.0167243	0.0117021
umls:C2919032	Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified	149	2.095887	0.0167243	0.0117021
umls:C0021345	Infectious Mononucleosis	22	2.091323	0.0167243	0.0117021
umls:C0032964	Pregnancy Complications, Hematologic	108	2.088528	0.0167243	0.0117021
umls:C0014457	Eosinophilia	102	2.085527	0.0167243	0.0117021
umls:C0019061	Hemolytic-Uremic Syndrome	49	2.084316	0.0167243	0.0117021
umls:C0019187	Hepatitis, Alcoholic	41	2.078615	0.0167243	0.0117021
umls:C0023893	Liver Cirrhosis, Experimental	149	2.077015	0.0167243	0.0117021
umls:C0206659	Embryonal Carcinoma	128	2.074546	0.0167243	0.0117021
umls:C0038395	Streptococcal Infections	35	2.071819	0.0167243	0.0117021
umls:C0032965	Pregnancy Complications, Infectious	24	2.065497	0.0167243	0.0117021
umls:C1292758	Precursor T-cell lymphoblastic lymphoma	12	2.060110	0.0167243	0.0117021
umls:C0022876	Premature Obstetric Labor	163	2.057221	0.0167243	0.0117021
umls:C0242488	Acute Lung Injury	57	2.056643	0.0167243	0.0117021
umls:C0011603	Dermatitis	126	2.055413	0.0167243	0.0117021
umls:C1719672	Severe Sepsis	66	2.054683	0.0167243	0.0117021
umls:C0008373	Cholesteatoma	33	2.053767	0.0167243	0.0117021
umls:C0162810	Cicatrix, Hypertrophic	51	2.052398	0.0167243	0.0117021
umls:C0026857	Musculoskeletal Diseases	107	2.051981	0.0167243	0.0117021
umls:C0032285	Pneumonia	312	2.051294	0.0167243	0.0117021
umls:C0034069	Pulmonary Fibrosis	290	2.045027	0.0167243	0.0117021
umls:C0024291	Lymphohistiocytosis, Hemophagocytic	69	2.044440	0.0167243	0.0117021
umls:C0220641	Lip and Oral Cavity Carcinoma	344	2.041983	0.0167243	0.0117021
umls:C0042345	Varicosity	39	2.039254	0.0167243	0.0117021
umls:C0403447	Chronic Kidney Insufficiency	149	2.037793	0.0167243	0.0117021
umls:C0149516	Chronic sinusitis	42	2.037077	0.0167243	0.0117021
umls:C0002940	Aneurysm	107	2.027965	0.0167243	0.0117021
umls:C0024236	Lymphedema	45	2.025914	0.0167243	0.0117021
umls:C0035369	Retroviridae Infections	54	2.025767	0.0167243	0.0117021
umls:C0026640	Mouth Neoplasms	173	2.021292	0.0167243	0.0117021
umls:C1519670	Tumor Angiogenesis	360	2.020365	0.0167243	0.0117021
umls:C0024115	Lung diseases	276	2.018978	0.0167243	0.0117021
umls:C0085390	Li-Fraumeni Syndrome	37	2.017408	0.0167243	0.0117021
umls:C0085437	Meningitis, Bacterial	32	2.016302	0.0167243	0.0117021
umls:C0151526	Premature Birth	235	2.015831	0.0167243	0.0117021
umls:C0856825	Acute GVH disease	90	2.015036	0.0167243	0.0117021
umls:C0867389	Chronic graft-versus-host disease	60	2.013438	0.0167243	0.0117021
umls:C0035455	Rhinitis	71	2.013250	0.0167243	0.0117021
umls:C0585362	Squamous cell carcinoma of mouth	42	2.012994	0.0167243	0.0117021
umls:C0035222	Respiratory Distress Syndrome, Adult	113	2.012097	0.0167243	0.0117021
umls:C0023484	Leukemia, Plasma Cell	35	2.011566	0.0167243	0.0117021
umls:C1334274	Invasive Carcinoma	134	2.010370	0.0167243	0.0117021
umls:C0340629	Aortic aneurysm without mention of rupture NOS	26	2.009482	0.0167243	0.0117021
umls:C0153381	Malignant neoplasm of mouth	344	2.008563	0.0167243	0.0117021
umls:C0036920	Sezary Syndrome	109	2.007829	0.0167243	0.0117021
umls:C0023646	Lichen Planus	16	2.007498	0.0167243	0.0117021
umls:C0007282	Carotid Stenosis	95	2.005633	0.0167243	0.0117021
umls:C0162872	Aortic Aneurysm, Thoracic	91	2.003847	0.0167243	0.0117021
umls:C1956391	Temporal Arteritis	13	2.001715	0.0167243	0.0117021
umls:C0019340	Herpes NOS	67	2.000683	0.0167243	0.0117021
umls:C0029172	Oral Submucous Fibrosis	45	1.998321	0.0167243	0.0117021
umls:C0339539	Familial Exudative Vitreoretinopathy	14	1.996388	0.0167243	0.0117021
umls:C0920646	Renal ischaemia	76	1.996294	0.0167243	0.0117021
umls:C0029118	Opportunistic Infections	25	1.996010	0.0167243	0.0117021
umls:C0014356	Enterocolitis	18	1.995200	0.0167243	0.0117021
umls:C0013537	Eclampsia	143	1.994462	0.0167243	0.0117021
umls:C1566590	Delayed Graft Function	13	1.993396	0.0167243	0.0117021
umls:C0033687	Proteinuria	67	1.991694	0.0167243	0.0117021
umls:C0009447	Common Variable Immunodeficiency	91	1.989739	0.0167243	0.0117021
umls:C0037928	Spinal Cord Diseases	32	1.988874	0.0167243	0.0117021
umls:C0374997	Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site	246	1.988762	0.0167243	0.0117021
umls:C0042131	Uterine Diseases	16	1.986974	0.0167243	0.0117021
umls:C0235989	Renal interstitial fibrosis	29	1.984096	0.0167243	0.0117021
umls:C0003130	Anoxia	306	1.983164	0.0167243	0.0117021
umls:C0030481	Tropical Spastic Paraparesis	33	1.983160	0.0167243	0.0117021
umls:C0036117	Salmonella infections	23	1.982932	0.0167243	0.0117021
umls:C0034362	Q Fever	20	1.982387	0.0167243	0.0117021
umls:C0025295	Meningitis, Pneumococcal	28	1.981475	0.0167243	0.0117021
umls:C0971858	Arthritis, Collagen-Induced	133	1.979505	0.0167243	0.0117021
umls:C0085090	Lymphoma, AIDS-Related	27	1.977390	0.0167243	0.0117021
umls:C0042373	Vascular Diseases	328	1.976202	0.0167243	0.0117021
umls:C0035328	Retinal Vein Occlusion	24	1.974219	0.0167243	0.0117021
umls:C0079218	Fibromatosis, Aggressive	53	1.973459	0.0167243	0.0117021
umls:C0162820	Dermatitis, Allergic Contact	83	1.972440	0.0167243	0.0117021
umls:C0017658	Glomerulonephritis	161	1.972250	0.0167243	0.0117021
umls:C0887833	Carcinoma, Pancreatic Ductal	55	1.971403	0.0167243	0.0117021
umls:C0017411	Female Genital Diseases	14	1.970766	0.0167243	0.0117021
umls:C0947751	Vascular inflammations	99	1.970520	0.0167243	0.0117021
umls:C0014170	Endometrial Neoplasms	220	1.968924	0.0167243	0.0117021
umls:C1318485	Liver regeneration disorder	75	1.967044	0.0167243	0.0117021
umls:C0023895	Liver diseases	446	1.966124	0.0167243	0.0117021
umls:C0332853	Anastomosis	18	1.963422	0.0252770	0.0176865
umls:C0027626	Neoplasm Invasiveness	147	1.961754	0.0167243	0.0117021
umls:C0040053	Thrombosis	105	1.957679	0.0167243	0.0117021
umls:C0034040	Puerperal Disorders	27	1.956047	0.0167243	0.0117021
umls:C0206677	Adenomatous Polyps	58	1.953494	0.0167243	0.0117021
umls:C0036202	Sarcoidosis	195	1.953156	0.0167243	0.0117021
umls:C2931384	Moyamoya disease 1	25	1.953123	0.0167243	0.0117021
umls:C1176475	Ductal Carcinoma	185	1.951113	0.0167243	0.0117021
umls:C1512433	Cervical high grade squamous intraepithelial lesion	15	1.951104	0.0252770	0.0176865
umls:C1260959	Drusen	38	1.949270	0.0167243	0.0117021
umls:C0015929	Fetal Diseases	122	1.947972	0.0167243	0.0117021
umls:C1762616	Meningioma, benign, no ICD-O subtype	191	1.947949	0.0167243	0.0117021
umls:C0027697	Nephritis	117	1.942911	0.0167243	0.0117021
umls:C0032914	Pre-Eclampsia	275	1.942371	0.0167243	0.0117021
umls:C0701807	Acute anterior uveitis	33	1.941898	0.0167243	0.0117021
umls:C0007772	Intracranial Arteriovenous Malformation	10	1.941728	0.0167243	0.0117021
umls:C0022548	Keloid	146	1.941089	0.0167243	0.0117021
umls:C0006274	Bronchiolitis, Viral	139	1.938986	0.0167243	0.0117021
umls:C0017612	Glaucoma, Open-Angle	77	1.935449	0.0167243	0.0117021
umls:C0036420	Localized scleroderma	19	1.935438	0.0339424	0.0237497
umls:C0153690	Secondary malignant neoplasm of bone	233	1.934874	0.0167243	0.0117021
umls:C1368683	Epithelioma	225	1.932421	0.0167243	0.0117021
umls:C0278996	Cancer of Head and Neck	361	1.932031	0.0167243	0.0117021
umls:C1719495	Aggressive periodontitis, generalized	29	1.929658	0.0167243	0.0117021
umls:C0346429	Multiple malignancy	164	1.927884	0.0167243	0.0117021
umls:C0012236	DiGeorge Syndrome	64	1.927164	0.0167243	0.0117021
umls:C0013295	Duodenal Ulcer	60	1.925079	0.0167243	0.0117021
umls:C0149939	Obstructive nephropathy	33	1.924865	0.0167243	0.0117021
umls:C1851585	MYELOPROLIFERATIVE DISORDER, CHRONIC, WITH EOSINOPHILIA	23	1.923578	0.0167243	0.0117021
umls:C0700613	Anxiety state	11	1.923350	0.0167243	0.0117021
umls:C0011615	Dermatitis, Atopic	333	1.919431	0.0167243	0.0117021
umls:C0333307	Superficial ulcer	98	1.918153	0.0167243	0.0117021
umls:C0031106	Periodontitis, Juvenile	69	1.916850	0.0167243	0.0117021
umls:C0020541	Hypertension, Portal	56	1.916834	0.0167243	0.0117021
umls:C0206708	Cervical Intraepithelial Neoplasia	179	1.916114	0.0167243	0.0117021
umls:C0014009	Empyema	11	1.915612	0.0167243	0.0117021
umls:C0023241	Legionnaires’ Disease	12	1.914343	0.0167243	0.0117021
umls:C0023267	Fibroid Tumor	270	1.914058	0.0167243	0.0117021
umls:C0003864	Arthritis	427	1.913413	0.0167243	0.0117021
umls:C0020473	Hyperlipidemia	174	1.912435	0.0167243	0.0117021
umls:C2004493	Leukemia, B-Cell	77	1.912346	0.0167243	0.0117021
umls:C0080233	Tooth Loss	14	1.912054	0.0252770	0.0176865
umls:C0018824	Heart valve disease	38	1.911223	0.0167243	0.0117021
umls:C0221204	Lytic lesion	11	1.910914	0.0167243	0.0117021
umls:C0032787	Postoperative Complications	48	1.910711	0.0167243	0.0117021
umls:C0034155	Purpura, Thrombotic Thrombocytopenic	32	1.910517	0.0167243	0.0117021
umls:C0236788	Bipolar II disorder	11	1.909844	0.0167243	0.0117021
umls:C0019080	Hemorrhage	54	1.909747	0.0167243	0.0117021
umls:C0013884	Filarial Elephantiases	16	1.909328	0.0252770	0.0176865
umls:C1444680	Posterior capsule opacification	12	1.907970	0.0252770	0.0176865
umls:C0004030	Aspergillosis	21	1.907854	0.0167243	0.0117021
umls:C0262985	Psoriasiform eczema	12	1.907710	0.0252770	0.0176865
umls:C0340543	Familial primary pulmonary hypertension	22	1.907194	0.0167243	0.0117021
umls:C0042164	Uveitis	100	1.907034	0.0167243	0.0117021
umls:C0032131	Plasmacytoma	63	1.906024	0.0167243	0.0117021
umls:C0003507	Aortic Valve Stenosis	72	1.905072	0.0167243	0.0117021
umls:C0035235	Respiratory Syncytial Virus Infections	217	1.903980	0.0167243	0.0117021
umls:C0024266	Lymphocytic Choriomeningitis	42	1.903168	0.0167243	0.0117021
umls:C0265004	Dilatation of aorta	14	1.902844	0.0339424	0.0237497
umls:C0263641	Epithelial hyperplasia of skin	33	1.901061	0.0167243	0.0117021
umls:C0278701	Gastric Adenocarcinoma	216	1.900705	0.0167243	0.0117021
umls:C0014072	Experimental Autoimmune Encephalomyelitis	305	1.895914	0.0167243	0.0117021
umls:C1621958	Glioblastoma Multiforme	370	1.892622	0.0167243	0.0117021
umls:C0079487	Helicobacter Infections	81	1.891091	0.0167243	0.0117021
umls:C0031154	Peritonitis	88	1.890533	0.0167243	0.0117021
umls:C0399440	Hereditary gingival fibromatosis	17	1.890429	0.0252770	0.0176865
umls:C0002448	Ameloblastoma	58	1.889633	0.0167243	0.0117021
umls:C0021831	Intestinal Diseases	54	1.889080	0.0167243	0.0117021
umls:C1306889	Peripheral arterial occlusive disease	14	1.886797	0.0339424	0.0237497
umls:C0011436	Dentinogenesis Imperfecta	11	1.885687	0.0167243	0.0117021
umls:C1861922	CAMPOMELIC DYSPLASIA	26	1.885473	0.0252770	0.0176865
umls:C0156181	Peritoneal adhesion	12	1.884784	0.0252770	0.0176865
umls:C3495801	Granulomatosis with polyangiitis	44	1.883371	0.0167243	0.0117021
umls:C0085083	Ovarian Hyperstimulation Syndrome	24	1.882728	0.0339424	0.0237497
umls:C0023055	Laryngeal neoplasm	89	1.880075	0.0167243	0.0117021
umls:C0742133	cervical cancer squamous cell	12	1.879654	0.0252770	0.0176865
umls:C0409959	Osteoarthritis, Knee	94	1.879294	0.0167243	0.0117021
umls:C0398686	Primary immune deficiency disorder	59	1.878575	0.0167243	0.0117021
umls:C0019158	Hepatitis	196	1.878264	0.0167243	0.0117021
umls:C1449563	Cardiomyopathy, Familial Idiopathic	159	1.877229	0.0167243	0.0117021
umls:C0265110	Cerebral Vasospasm	13	1.875252	0.0411477	0.0287912
umls:C0268731	Renal glomerular disease	81	1.874205	0.0167243	0.0117021
umls:C0019829	Hodgkin Disease	306	1.874098	0.0167243	0.0117021
umls:C0007766	Intracranial Aneurysm	96	1.873716	0.0167243	0.0117021
umls:C0543697	Mixed cryoglobulinemia	24	1.873631	0.0339424	0.0237497
umls:C0278484	Malignant neoplasm of colon stage IV	62	1.873243	0.0167243	0.0117021
umls:C0850666	Helicobacter pylori infection	225	1.872858	0.0167243	0.0117021
umls:C0345967	Malignant mesothelioma	227	1.872669	0.0167243	0.0117021
umls:C0036220	Kaposi Sarcoma	147	1.871938	0.0167243	0.0117021
umls:C0153349	Malignant neoplasm of tongue	41	1.871673	0.0167243	0.0117021
umls:C0153601	Malignant neoplasm of penis	22	1.871458	0.0252770	0.0176865
umls:C0009782	Connective Tissue Diseases	159	1.870142	0.0167243	0.0117021
umls:C0085786	Hamman-Rich syndrome	29	1.869605	0.0167243	0.0117021
umls:C0268363	Osteogenesis imperfecta type IV (disorder)	11	1.868969	0.0339424	0.0237497
umls:C0038358	Gastric ulcer	87	1.868234	0.0167243	0.0117021
umls:C0023281	Leishmaniasis	45	1.867381	0.0167243	0.0117021
umls:C0009319	Colitis	414	1.864835	0.0167243	0.0117021
umls:C0018378	Guillain-Barre Syndrome	39	1.864703	0.0167243	0.0117021
umls:C0042344	Varicose Ulcer	35	1.864204	0.0167243	0.0117021
umls:C0024143	Lupus Nephritis	161	1.863456	0.0167243	0.0117021
umls:C0031099	Periodontitis	198	1.862201	0.0167243	0.0117021
umls:C0035439	Rheumatic Heart Disease	41	1.861155	0.0167243	0.0117021
umls:C0349566	Squamous cell carcinoma of tongue	98	1.861022	0.0167243	0.0117021
umls:C0278488	Carcinoma breast stage IV	280	1.860954	0.0167243	0.0117021
umls:C2607914	Allergic rhinitis (disorder)	120	1.860865	0.0167243	0.0117021
umls:C0154084	Stage 0 Breast Carcinoma	13	1.860612	0.0411477	0.0287912
umls:C0178238	Intestinal infectious disease (disorder)	12	1.860562	0.0339424	0.0237497
umls:C0239946	Fibrosis, Liver	271	1.860536	0.0167243	0.0117021
umls:C0376620	Pouchitis	12	1.858472	0.0339424	0.0237497
umls:C0268351	Cutis Laxa, Autosomal Recessive, Type I	14	1.857879	0.0339424	0.0237497
umls:C0039445	Hereditary hemorrhagic telangiectasia	17	1.856179	0.0339424	0.0237497
umls:C0026277	Mixed Salivary Gland Tumor	92	1.854383	0.0167243	0.0117021
umls:C0017668	Focal glomerulosclerosis	85	1.852332	0.0167243	0.0117021
umls:C0018081	Gonorrhea	33	1.852291	0.0252770	0.0176865
umls:C0000786	Spontaneous abortion	191	1.850923	0.0167243	0.0117021
umls:C0006267	Bronchiectasis	33	1.849576	0.0252770	0.0176865
umls:C1367654	Marginal Zone B-Cell Lymphoma	38	1.849461	0.0167243	0.0117021
umls:C0334579	Anaplastic astrocytoma	125	1.847827	0.0167243	0.0117021
umls:C0022602	Actinic keratosis	69	1.847822	0.0167243	0.0117021
umls:C0028064	Niemann-Pick Diseases	10	1.846400	0.0252770	0.0176865
umls:C3272363	Ischemic Cerebrovascular Accident	271	1.845240	0.0167243	0.0117021
umls:C1290886	Chronic inflammatory disorder	59	1.845112	0.0167243	0.0117021
umls:C0263454	Chloracne	36	1.844147	0.0167243	0.0117021
umls:C1301355	Myelodysplastic-Myeloproliferative Diseases	17	1.842531	0.0339424	0.0237497
umls:C0409651	Seropositive rheumatoid arthritis	16	1.842431	0.0411477	0.0287912
umls:C0007873	Uterine Cervical Neoplasm	146	1.842088	0.0167243	0.0117021
umls:C0023343	Leprosy	105	1.841018	0.0167243	0.0117021
umls:C0020443	Hypercholesterolemia	150	1.840963	0.0167243	0.0117021
umls:C0162869	Aneurysm, Ruptured	22	1.840785	0.0339424	0.0237497
umls:C0162526	AIDS-Related Opportunistic Infections	10	1.839548	0.0339572	0.0237601
umls:C0008497	Choriocarcinoma	226	1.838158	0.0167243	0.0117021
umls:C0004626	Pneumonia, Bacterial	24	1.837186	0.0411477	0.0287912
umls:C0005411	Biliary Atresia	69	1.837120	0.0167243	0.0117021
umls:C0022354	Jaundice, Obstructive	12	1.836877	0.0339424	0.0237497
umls:C0019100	Severe Dengue	59	1.831721	0.0167243	0.0117021
umls:C0206694	Mucoepidermoid Carcinoma	59	1.830709	0.0167243	0.0117021
umls:C0042133	Uterine Fibroids	276	1.830595	0.0167243	0.0117021
umls:C0019069	Hemophilia A	73	1.830296	0.0167243	0.0117021
umls:C0558353	Tongue Carcinoma	44	1.829262	0.0252770	0.0176865
umls:C0282350	Sexual abuse	12	1.827923	0.0339424	0.0237497
umls:C0034065	Pulmonary Embolism	54	1.827452	0.0167243	0.0117021
umls:C0856053	Leukemia secondary	17	1.827178	0.0339424	0.0237497
umls:C0013720	Ehlers-Danlos Syndrome	52	1.824302	0.0167243	0.0117021
umls:C0079588	Ichthyosis, X-Linked	70	1.823989	0.0167243	0.0117021
umls:C1378703	Renal carcinoma	387	1.823203	0.0167243	0.0117021
umls:C1290884	Inflammatory disorder	183	1.822401	0.0167243	0.0117021
umls:C1876165	Copper-Overload Cirrhosis	11	1.819774	0.0411477	0.0287912
umls:C0149521	Pancreatitis, Chronic	214	1.819636	0.0167243	0.0117021
umls:C0333186	Restenosis	169	1.819625	0.0167243	0.0117021
umls:C0699949	airway disease	64	1.819065	0.0167243	0.0117021
umls:C0006663	Calcinosis	82	1.817570	0.0167243	0.0117021
umls:C0206180	Ki-1+ Anaplastic Large Cell Lymphoma	214	1.817324	0.0167243	0.0117021
umls:C0002793	Anaplasia	191	1.816733	0.0167243	0.0117021
umls:C0008384	Cholesterol Ester Storage Disease	11	1.816395	0.0411477	0.0287912
umls:C0015695	Fatty Liver	286	1.815854	0.0167243	0.0117021
umls:C0023465	Acute monocytic leukemia	64	1.814703	0.0167243	0.0117021
umls:C0035126	Reperfusion Injury	271	1.814696	0.0167243	0.0117021
umls:C0013595	Eczema	281	1.813419	0.0167243	0.0117021
umls:C0036205	Sarcoidosis, Pulmonary	41	1.813243	0.0167243	0.0117021
umls:C0038013	Ankylosing spondylitis	187	1.812473	0.0167243	0.0117021
umls:C0011616	Contact Dermatitis	62	1.811122	0.0167243	0.0117021
umls:C0013312	Dupuytren Contracture	16	1.810505	0.0471454	0.0329879
umls:C1333171	Primary Cutaneous Follicle Center Lymphoma	11	1.809953	0.0411477	0.0287912
umls:C0948089	Acute Coronary Syndrome	241	1.808814	0.0167243	0.0117021
umls:C0020507	Hyperplasia	122	1.808539	0.0167243	0.0117021
umls:C0334520	Teratoma, Malignant	17	1.808398	0.0471454	0.0329879
umls:C0521607	Peritoneal Fibrosis	29	1.807570	0.0339424	0.0237497
umls:C0010495	Cutis Laxa	26	1.804516	0.0411477	0.0287912
umls:C0017152	Gastritis	153	1.804121	0.0167243	0.0117021
umls:C0267375	Chronic colitis	24	1.802578	0.0471454	0.0329879
umls:C0008312	Primary biliary cirrhosis	201	1.802572	0.0167243	0.0117021
umls:C0024232	Lymphatic Metastasis	133	1.802518	0.0167243	0.0117021
umls:C0917804	Arteriovenous Malformations, Cerebral	15	1.802402	0.0471454	0.0329879
umls:C0235653	Malignant neoplasm of female breast	45	1.802396	0.0252770	0.0176865
umls:C0042487	Venous Thrombosis	75	1.802368	0.0167243	0.0117021
umls:C0042165	Anterior uveitis	28	1.802043	0.0471454	0.0329879
umls:C0021361	Female infertility	53	1.801870	0.0167243	0.0117021
umls:C0948008	Ischemic stroke	307	1.801617	0.0167243	0.0117021
umls:C0008149	Chlamydia Infections	61	1.801275	0.0167243	0.0117021
umls:C3642347	Basal-Like Breast Carcinoma	15	1.800277	0.0471454	0.0329879
umls:C0018915	Hemangioendothelioma	11	1.800217	0.0411477	0.0287912
umls:C0029458	Osteoporosis, Postmenopausal	74	1.799164	0.0167243	0.0117021
umls:C0152018	Esophageal carcinoma	445	1.798540	0.0167243	0.0117021
umls:C0033054	Prenatal Exposure Delayed Effects	44	1.797632	0.0252770	0.0176865
umls:C0085220	Cerebral Amyloid Angiopathy	35	1.797443	0.0167243	0.0117021
umls:C1336527	Carcinoma of urinary bladder, superficial	33	1.795379	0.0252770	0.0176865
umls:C0032927	Precancerous Conditions	351	1.794377	0.0167243	0.0117021
umls:C0022578	Keratoconus	66	1.794114	0.0167243	0.0117021
umls:C1561643	Chronic Kidney Diseases	229	1.793931	0.0167243	0.0117021
umls:C0853879	Invasive breast carcinoma	321	1.792351	0.0167243	0.0117021
umls:C0007104	Female Breast Carcinoma	48	1.792038	0.0339424	0.0237497
umls:C0037286	Skin Neoplasms	274	1.789932	0.0167243	0.0117021
umls:C0002351	Altitude Sickness	16	1.788366	0.0471454	0.0329879
umls:C0016034	Breast Fibrocystic Disease	55	1.788150	0.0167243	0.0117021
umls:C3494652	Severe dementia	11	1.784819	0.0471454	0.0329879
umls:C0376628	Chromosome Breakage	15	1.784685	0.0471454	0.0329879
umls:C0270726	Alexander Disease	16	1.784195	0.0471454	0.0329879
umls:C0031039	Pericardial effusion	22	1.783537	0.0471454	0.0329879
umls:C0015393	Eye Abnormalities	36	1.783211	0.0167243	0.0117021
umls:C0024282	Lymphocytosis	42	1.782982	0.0167243	0.0117021
umls:C3539878	Triple Negative Breast Neoplasms	388	1.782919	0.0167243	0.0117021
umls:C0001486	Adenovirus Infections	63	1.782503	0.0167243	0.0117021
umls:C0280803	Primary central nervous system lymphoma	39	1.782132	0.0253258	0.0177206
umls:C0032231	Pleurisy	22	1.780922	0.0471454	0.0329879
umls:C0007789	Cerebral Palsy	65	1.780762	0.0167243	0.0117021
umls:C0267941	Pancreatitis, Acute Necrotizing	30	1.780754	0.0411477	0.0287912
umls:C0009917	Contracture	35	1.780570	0.0252770	0.0176865
umls:C2609414	Acute kidney injury	96	1.776528	0.0167243	0.0117021
umls:C0033999	Pterygium	53	1.775969	0.0167243	0.0117021
umls:C0010606	Adenoid Cystic Carcinoma	185	1.775475	0.0167243	0.0117021
umls:C0265268	Adams Oliver syndrome	11	1.775360	0.0471454	0.0329879
umls:C0018798	Congenital Heart Defects	210	1.773590	0.0167243	0.0117021
umls:C0038354	Stomach Diseases	31	1.771818	0.0339424	0.0237497
umls:C0018133	Graft-vs-Host Disease	230	1.770887	0.0167243	0.0117021
umls:C0011644	Scleroderma	132	1.770086	0.0167243	0.0117021
umls:C1279420	Anxiety neurosis (finding)	10	1.769379	0.0411477	0.0287912
umls:C2986665	Early-Stage Breast Carcinoma	57	1.768873	0.0252770	0.0176865
umls:C0034063	Pulmonary Edema	66	1.768723	0.0167243	0.0117021
umls:C0278883	Metastatic melanoma	272	1.768577	0.0167243	0.0117021
umls:C1333762	Gastric Cardia Adenocarcinoma	31	1.766686	0.0339424	0.0237497
umls:C0037199	Sinusitis	29	1.766470	0.0471454	0.0329879
umls:C0007114	Malignant neoplasm of skin	192	1.765509	0.0167243	0.0117021
umls:C0008626	Congenital chromosomal disease	440	1.763545	0.0167243	0.0117021
umls:C0339543	Epiretinal Membrane	30	1.763514	0.0411477	0.0287912
umls:C0003838	Arterial Occlusive Diseases	37	1.762074	0.0167243	0.0117021
umls:C1096184	West Nile viral infection	64	1.761705	0.0252770	0.0176865
umls:C0149678	Epstein-Barr Virus Infections	174	1.761387	0.0167243	0.0117021
umls:C0024305	Lymphoma, Non-Hodgkin	426	1.761370	0.0167243	0.0117021
umls:C0013238	Dry Eye Syndromes	36	1.760131	0.0167243	0.0117021
umls:C0020217	Hydatidiform Mole	48	1.759795	0.0411477	0.0287912
umls:C0242706	Hyperoxia	42	1.759420	0.0252770	0.0176865
umls:C0013371	Shigella Infections	51	1.758149	0.0339424	0.0237497
umls:C0079772	T-Cell Lymphoma	239	1.758118	0.0167243	0.0117021
umls:C0008313	Cholangitis, Sclerosing	69	1.756650	0.0167243	0.0117021
umls:C0004610	Bacteremia	73	1.756270	0.0167243	0.0117021
umls:C0013182	Drug Allergy	52	1.753839	0.0252770	0.0176865
umls:C0007103	Malignant neoplasm of endometrium	413	1.751976	0.0167243	0.0117021
umls:C1883486	Uterine Corpus Cancer	413	1.751976	0.0167243	0.0117021
umls:C0079744	Diffuse Large B-Cell Lymphoma	459	1.751193	0.0167243	0.0117021
umls:C0279628	Adenocarcinoma Of Esophagus	229	1.751174	0.0167243	0.0117021
umls:C0006272	Bronchiolitis Obliterans	40	1.750466	0.0167243	0.0117021
umls:C0002965	Angina, Unstable	65	1.749311	0.0167243	0.0117021
umls:C1559271	Non-Malignant Ascites Adverse Event	146	1.748952	0.0167243	0.0117021
umls:C3714636	Pneumonitis	46	1.747471	0.0340331	0.0238131
umls:C0020474	Hyperlipidemia, Familial Combined	67	1.746435	0.0167243	0.0117021
umls:C0546837	Malignant neoplasm of esophagus	485	1.745507	0.0167243	0.0117021
umls:C0333997	Lymphoid hyperplasia	15	1.745000	0.0471454	0.0329879
umls:C0004997	Benign Ovarian Neoplasm	32	1.743089	0.0411477	0.0287912
umls:C0524910	Hepatitis C, Chronic	327	1.741859	0.0167243	0.0117021
umls:C0029445	Bone necrosis	40	1.741560	0.0167243	0.0117021
umls:C0949690	Spondylarthritis	47	1.740370	0.0411477	0.0287912
umls:C0751967	Multiple Sclerosis, Relapsing-Remitting	77	1.739242	0.0167243	0.0117021
umls:C1623038	Cirrhosis	307	1.738872	0.0167243	0.0117021
umls:C0206139	Lichen Planus, Oral	64	1.737950	0.0252770	0.0176865
umls:C0524909	Hepatitis B, Chronic	185	1.736431	0.0167243	0.0117021
umls:C1168327	High-Grade Prostatic Intraepithelial Neoplasia	80	1.734454	0.0167243	0.0117021
umls:C0600452	Hepatopulmonary Syndrome	81	1.733940	0.0167243	0.0117021
umls:C0042384	Vasculitis	105	1.733712	0.0167243	0.0117021
umls:C0040592	Trachoma	41	1.733263	0.0252770	0.0176865
umls:C0155862	Streptococcal pneumonia	25	1.733116	0.0471454	0.0329879
umls:C1335302	Pancreatic Ductal Adenocarcinoma	462	1.730426	0.0167243	0.0117021
umls:C0005779	Blood Coagulation Disorders	102	1.730172	0.0167243	0.0117021
umls:C0242647	Mucosa-Associated Lymphoid Tissue Lymphoma	142	1.727809	0.0167243	0.0117021
umls:C1840264	IMMUNE SUPPRESSION	61	1.726027	0.0252770	0.0176865
umls:C0024131	Lupus Vulgaris	238	1.725299	0.0167243	0.0117021
umls:C0007787	Transient Ischemic Attack	153	1.725171	0.0167243	0.0117021
umls:C0023290	Leishmaniasis, Visceral	58	1.725145	0.0252770	0.0176865
umls:C0026850	Muscular Dystrophy	182	1.725115	0.0167243	0.0117021
umls:C0206638	Giant Cell Tumor of Bone	58	1.724844	0.0252770	0.0176865
umls:C0238190	Inclusion Body Myositis (disorder)	58	1.723197	0.0252770	0.0176865
umls:C0206698	Cholangiocarcinoma	333	1.722673	0.0167243	0.0117021
umls:C0085110	Severe Combined Immunodeficiency	420	1.718085	0.0167243	0.0117021
umls:C1527390	Neoplasms, Intracranial	54	1.715787	0.0339471	0.0237530
umls:C0221757	alpha 1-Antitrypsin Deficiency	45	1.715674	0.0339626	0.0237638
umls:C0005695	Bladder Neoplasm	390	1.715393	0.0167243	0.0117021
umls:C0494165	Secondary malignant neoplasm of liver	349	1.714033	0.0167243	0.0117021
umls:C0206734	Hemangioblastoma	32	1.713130	0.0411477	0.0287912
umls:C1518171	Malignant Conversion	40	1.710506	0.0167243	0.0117021
umls:C0341439	Chronic liver disease	108	1.709358	0.0167243	0.0117021
umls:C3539909	Allergic disposition	149	1.708266	0.0167243	0.0117021
umls:C0025286	Meningioma	381	1.707166	0.0167243	0.0117021
umls:C1519346	Skin Carcinogenesis	95	1.706870	0.0339424	0.0237497
umls:C1511789	Desmoplastic	68	1.706768	0.0167243	0.0117021
umls:C0269102	Endometrioma	55	1.706713	0.0411477	0.0287912
umls:C0238394	Female Pseudohermaphroditism	43	1.706024	0.0339424	0.0237497
umls:C1134719	Invasive Ductal Breast Carcinoma	205	1.704863	0.0167243	0.0117021
umls:C0027726	Nephrotic Syndrome	144	1.704760	0.0167243	0.0117021
umls:C0403592	Chronic rejection of renal transplant	35	1.704078	0.0339424	0.0237497
umls:C1333064	Classical Hodgkin’s Lymphoma	100	1.702394	0.0167243	0.0117021
umls:C3714757	Juvenile rheumatoid arthritis	139	1.701053	0.0252770	0.0176865
umls:C0279702	Conventional (Clear Cell) Renal Cell Carcinoma	304	1.699252	0.0167243	0.0117021
umls:C0042029	Urinary tract infection	64	1.698838	0.0252770	0.0176865
umls:C2711227	Steatohepatitis	179	1.696872	0.0167243	0.0117021
umls:C0030524	Paratuberculosis	32	1.694411	0.0411477	0.0287912
umls:C0376545	Hematologic Neoplasms	399	1.692548	0.0167243	0.0117021
umls:C0020517	Hypersensitivity	121	1.692144	0.0252770	0.0176865
umls:C0851140	Carcinoma in situ of uterine cervix	48	1.689809	0.0471454	0.0329879
umls:C0266929	Chronic Periodontitis	127	1.689439	0.0252770	0.0176865
umls:C0011311	Dengue Fever	140	1.689382	0.0252770	0.0176865
umls:C0341858	Endometriosis of uterus	48	1.688473	0.0471454	0.0329879
umls:C0006413	Burkitt Lymphoma	167	1.687532	0.0167243	0.0117021
umls:C0007193	Cardiomyopathy, Dilated	328	1.687212	0.0167243	0.0117021
umls:C0019159	Hepatitis A	188	1.686011	0.0167243	0.0117021
umls:C0334590	Anaplastic Oligodendroglioma	121	1.684965	0.0252770	0.0176865
umls:C0392707	Atopy	42	1.684716	0.0341043	0.0238629
umls:C0007124	Noninfiltrating Intraductal Carcinoma	257	1.683990	0.0167243	0.0117021
umls:C0036983	Septic Shock	48	1.682822	0.0471454	0.0329879
umls:C0039103	Synovitis	76	1.682665	0.0167243	0.0117021
umls:C0278678	Metastatic Renal Cell Cancer	40	1.681762	0.0252770	0.0176865
umls:C0031090	Periodontal Diseases	94	1.681692	0.0339424	0.0237497
umls:C0027439	Nasopharyngeal Neoplasms	61	1.681166	0.0411477	0.0287912
umls:C0555198	Malignant Glioma	356	1.681136	0.0167243	0.0117021
umls:C0280785	Diffuse Astrocytoma	37	1.680705	0.0411477	0.0287912
umls:C0242852	Proliferative vitreoretinopathy	52	1.680549	0.0471454	0.0329879
umls:C2931852	Clear-cell metastatic renal cell carcinoma	92	1.680199	0.0252770	0.0176865
umls:C1292769	Precursor B-cell lymphoblastic leukemia	297	1.680059	0.0167243	0.0117021
umls:C0023892	Biliary cirrhosis	100	1.679717	0.0252770	0.0176865
umls:C0020542	Pulmonary Hypertension	283	1.679477	0.0167243	0.0117021
umls:C0023487	Acute Promyelocytic Leukemia	359	1.675116	0.0167243	0.0117021
umls:C0030809	Pemphigus Vulgaris	58	1.675058	0.0252770	0.0176865
umls:C0040038	Thromboembolism	87	1.674121	0.0252770	0.0176865
umls:C0007570	Celiac Disease	268	1.674037	0.0167243	0.0117021
umls:C0010674	Cystic Fibrosis	330	1.673220	0.0167243	0.0117021
umls:C0026946	Mycoses	193	1.673162	0.0167243	0.0117021
umls:C0339143	Thyroid associated opthalmopathies	71	1.672860	0.0167243	0.0117021
umls:C0026896	Myasthenia Gravis	139	1.672817	0.0252770	0.0176865
umls:C0029134	Optic Neuritis	32	1.672727	0.0411477	0.0287912
umls:C0005967	Bone neoplasms	84	1.672604	0.0252770	0.0176865
umls:C0746102	Chronic lung disease	47	1.672341	0.0411477	0.0287912
umls:C0860207	Drug-Induced Liver Injury	135	1.671859	0.0252770	0.0176865
umls:C0021051	Immunologic Deficiency Syndromes	349	1.671372	0.0167243	0.0117021
umls:C0001925	Albuminuria	111	1.671213	0.0167243	0.0117021
umls:C0940937	precancerous lesions	91	1.670272	0.0252770	0.0176865
umls:C0019621	Histiocytosis, Langerhans-Cell	48	1.669594	0.0471454	0.0329879
umls:C0024138	Lupus Erythematosus, Discoid	244	1.668026	0.0167243	0.0117021
umls:C0178664	Glomerulosclerosis (disorder)	63	1.667437	0.0411477	0.0287912
umls:C0025500	Mesothelioma	326	1.667059	0.0167243	0.0117021
umls:C0016781	Fuchs Endothelial Dystrophy	35	1.666732	0.0411477	0.0287912
umls:C0993582	Arthritis, Experimental	133	1.666548	0.0252770	0.0176865
umls:C0403416	Idiopathic crescentic glomerulonephritis	34	1.666285	0.0411477	0.0287912
umls:C0040028	Thrombocythemia, Essential	124	1.665844	0.0252770	0.0176865
umls:C0162557	Liver Failure, Acute	89	1.665768	0.0252770	0.0176865
umls:C1846064	Recurrent infections (sinusitis and bacterial pneumonia and meningitis)	43	1.665752	0.0339424	0.0237497
umls:C0024312	Lymphopenia	60	1.665304	0.0411477	0.0287912
umls:C0238463	Papillary thyroid carcinoma	379	1.665155	0.0167243	0.0117021
umls:C0345904	Malignant neoplasm of liver	481	1.664363	0.0167243	0.0117021
umls:C0745744	End Stage Liver Disease	32	1.661846	0.0471454	0.0329879
umls:C0001883	Airway Obstruction	37	1.660498	0.0411477	0.0287912
umls:C0011884	Diabetic Retinopathy	191	1.658249	0.0167243	0.0117021
umls:C0409974	Lupus Erythematosus	284	1.657680	0.0167243	0.0117021
umls:C1318544	M5b Acute differentiated monocytic leukemia	73	1.657522	0.0167243	0.0117021
umls:C0008925	Cleft Palate	216	1.656933	0.0167243	0.0117021
umls:C0033847	Pseudoxanthoma Elasticum	41	1.656699	0.0411477	0.0287912
umls:C0085129	Bronchial Hyperreactivity	128	1.656006	0.0252770	0.0176865
umls:C0037299	Skin Ulcer	32	1.654595	0.0471454	0.0329879
umls:C0410528	Skeletal dysplasia	66	1.653604	0.0252770	0.0176865
umls:C0238301	Cancer of Nasopharynx	80	1.651272	0.0252770	0.0176865
umls:C0339573	Glaucoma, Primary Open Angle	141	1.650596	0.0252770	0.0176865
umls:C0035412	Rhabdomyosarcoma	307	1.650114	0.0167243	0.0117021
umls:C1334177	Infiltrating Cervical Carcinoma	50	1.649179	0.0471454	0.0329879
umls:C0340288	Stable angina	66	1.648267	0.0252770	0.0176865
umls:C0741923	cardiac event	38	1.647709	0.0411477	0.0287912
umls:C0039483	Giant Cell Arteritis	97	1.646739	0.0339424	0.0237497
umls:C0023896	Alcoholic Liver Diseases	86	1.646518	0.0252770	0.0176865
umls:C0004238	Atrial Fibrillation	104	1.646495	0.0253254	0.0177203
umls:C1328840	Autoimmune Lymphoproliferative Syndrome	38	1.645828	0.0411477	0.0287912
umls:C0376544	Hematopoietic Neoplasms	140	1.645069	0.0252770	0.0176865
umls:C0001175	Acquired Immunodeficiency Syndrome	108	1.644807	0.0252770	0.0176865
umls:C0279000	Liver and Intrahepatic Biliary Tract Carcinoma	403	1.644307	0.0167243	0.0117021
umls:C3463897	HYDATIDIFORM MOLE, RECURRENT, 1	44	1.644252	0.0411477	0.0287912
umls:C0024796	Marfan Syndrome	47	1.644043	0.0471454	0.0329879
umls:C0577631	Carotid Atherosclerosis	88	1.643938	0.0252770	0.0176865
umls:C0023493	Adult T-Cell Lymphoma/Leukemia	366	1.641075	0.0167243	0.0117021
umls:C0376634	Craniofacial Abnormalities	175	1.640417	0.0167243	0.0117021
umls:C0006309	Brucellosis	36	1.639944	0.0471454	0.0329879
umls:C0018203	Chronic granulomatous disease	60	1.638802	0.0471454	0.0329879
umls:C0011303	Demyelinating Diseases	72	1.638019	0.0167243	0.0117021
umls:C0206685	Acinar Cell Carcinoma	32	1.636366	0.0471454	0.0329879
umls:C0018995	Hemochromatosis	76	1.634489	0.0252770	0.0176865
umls:C0030305	Pancreatitis	149	1.633939	0.0252770	0.0176865
umls:C0242383	Age related macular degeneration	331	1.632937	0.0167243	0.0117021
umls:C0022408	Arthropathy	95	1.632616	0.0339424	0.0237497
umls:C0852949	Arteriopathic disease	44	1.632289	0.0411477	0.0287912
umls:C0032962	Pregnancy Complications	94	1.630460	0.0339424	0.0237497
umls:C0280141	Acute Undifferentiated Leukemia	70	1.628983	0.0252770	0.0176865
umls:C0948192	Primary infection NOS	46	1.627992	0.0411613	0.0288007
umls:C0037274	Dermatologic disorders	363	1.627519	0.0167243	0.0117021
umls:C0027686	Pathologic Neovascularization	62	1.626941	0.0471454	0.0329879
umls:C0584960	Factor V Leiden mutation	40	1.625852	0.0411477	0.0287912
umls:C0025007	Measles	120	1.624298	0.0341106	0.0238674
umls:C0238790	bone destruction	66	1.623999	0.0339424	0.0237497
umls:C0004943	Behcet Syndrome	229	1.622649	0.0167243	0.0117021
umls:C0079745	Lymphoma, Large-Cell, Follicular	137	1.622214	0.0252770	0.0176865
umls:C0314719	Dryness of eye	32	1.621884	0.0471454	0.0329879
umls:C0011065	Cessation of life	117	1.619749	0.0341970	0.0239278
umls:C0008924	Cleft Lip	173	1.619444	0.0167243	0.0117021
umls:C0017525	Giant Cell Tumors	63	1.618874	0.0471454	0.0329879
umls:C0311375	Arsenic Poisoning	63	1.618215	0.0471454	0.0329879
umls:C0018213	Graves Disease	260	1.616571	0.0167243	0.0117021
umls:C0026691	Mucocutaneous Lymph Node Syndrome	145	1.615733	0.0339424	0.0237497
umls:C0006287	Bronchopulmonary Dysplasia	174	1.615642	0.0167243	0.0117021
umls:C0595921	Intraocular pressure disorder	84	1.615596	0.0252770	0.0176865
umls:C0878500	Intraepithelial Neoplasia	106	1.615096	0.0253263	0.0177209
umls:C0151546	Oral Cavity Carcinoma	73	1.614308	0.0252770	0.0176865
umls:C0027430	Nasal Polyps	141	1.613962	0.0252770	0.0176865
umls:C3665444	Neutrophilia (disorder)	40	1.613150	0.0471454	0.0329879
umls:C0598608	Hyperhomocysteinemia	98	1.610941	0.0411477	0.0287912
umls:C0740392	Infarction, Middle Cerebral Artery	77	1.610467	0.0252770	0.0176865
umls:C0022661	Kidney Failure, Chronic	483	1.610171	0.0167243	0.0117021
umls:C0152171	Idiopathic pulmonary hypertension	181	1.609855	0.0167243	0.0117021
umls:C0085096	Peripheral Vascular Diseases	94	1.609822	0.0411477	0.0287912
umls:C0085278	Antiphospholipid Syndrome	45	1.609807	0.0411477	0.0287912
umls:C0333875	High-Grade Squamous Intraepithelial Lesions	71	1.608227	0.0252770	0.0176865
umls:C0162309	Adrenoleukodystrophy	117	1.606103	0.0341970	0.0239278
umls:C0005940	Bone Diseases	137	1.605087	0.0252770	0.0176865
umls:C0220650	Metastatic malignant neoplasm to brain	105	1.604609	0.0253255	0.0177204
umls:C0024668	Mammary Neoplasms, Experimental	185	1.604462	0.0252770	0.0176865
umls:C0280324	Laryngeal Squamous Cell Carcinoma	110	1.603225	0.0339424	0.0237497
umls:C0740457	Malignant neoplasm of kidney	337	1.600983	0.0167243	0.0117021
umls:C0008625	Chromosome Aberrations	76	1.600004	0.0252770	0.0176865
umls:C0023904	Liver Neoplasms, Experimental	78	1.597632	0.0339424	0.0237497
umls:C0007138	Carcinoma, Transitional Cell	332	1.597320	0.0167243	0.0117021
umls:C0238198	Gastrointestinal Stromal Tumors	279	1.596899	0.0167243	0.0117021
umls:C0085655	Polymyositis	80	1.596428	0.0339424	0.0237497
umls:C0007133	Carcinoma, Papillary	211	1.595170	0.0167243	0.0117021
umls:C0024301	Lymphoma, Follicular	300	1.594771	0.0167243	0.0117021
umls:C0017563	Gingival Diseases	74	1.594420	0.0339424	0.0237497
umls:C0017601	Glaucoma	180	1.591954	0.0252770	0.0176865
umls:C0027059	Myocarditis	83	1.590910	0.0252770	0.0176865
umls:C0400966	Non-alcoholic Fatty Liver Disease	243	1.589232	0.0167243	0.0117021
umls:C0206681	Adenocarcinoma, Clear Cell	88	1.589081	0.0339424	0.0237497
umls:C0002874	Aplastic Anemia	111	1.584673	0.0339424	0.0237497
umls:C0553723	Squamous cell carcinoma of skin	126	1.580811	0.0411477	0.0287912
umls:C0035435	Rheumatism	86	1.580523	0.0411477	0.0287912
umls:C0027055	Myocardial Reperfusion Injury	132	1.580072	0.0252770	0.0176865
umls:C0007115	Malignant neoplasm of thyroid	393	1.580067	0.0167243	0.0117021
umls:C0023492	Leukemia, T-Cell	270	1.579952	0.0167243	0.0117021
umls:C0020459	Hyperinsulinism	211	1.577699	0.0167243	0.0117021
umls:C0014038	Encephalitis	106	1.575512	0.0341970	0.0239278
umls:C0019348	Herpes Simplex Infections	425	1.574852	0.0167243	0.0117021
umls:C0006012	Borderline Personality Disorder	146	1.573681	0.0339424	0.0237497
umls:C0024667	Animal Mammary Neoplasms	178	1.572727	0.0252770	0.0176865
umls:C0026846	Muscular Atrophy	157	1.570307	0.0252770	0.0176865
umls:C0346957	Disseminated Malignant Neoplasm	132	1.570126	0.0339572	0.0237601
umls:C0017185	Gastrointestinal Neoplasms	102	1.570089	0.0411477	0.0287912
umls:C0016057	Fibrosarcoma	224	1.567713	0.0167243	0.0117021
umls:C0041327	Tuberculosis, Pulmonary	170	1.566847	0.0252770	0.0176865
umls:C0021053	Immune System Diseases	142	1.563548	0.0411477	0.0287912
umls:C0278601	Inflammatory Breast Carcinoma	73	1.563244	0.0339424	0.0237497
umls:C0021655	Insulin Resistance	249	1.558897	0.0167243	0.0117021
umls:C0035372	Rett Syndrome	111	1.556926	0.0411477	0.0287912
umls:C0007117	Basal cell carcinoma	86	1.556102	0.0411477	0.0287912
umls:C0279671	Cervical Squamous Cell Carcinoma	110	1.553358	0.0411477	0.0287912
umls:C1512409	Hepatocarcinogenesis	399	1.553262	0.0167243	0.0117021
umls:C1527336	Sjogren’s Syndrome	88	1.550936	0.0471454	0.0329879
umls:C0022660	Kidney Failure, Acute	151	1.550136	0.0471454	0.0329879
umls:C1961099	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	287	1.548878	0.0167243	0.0117021
umls:C0338106	Adenocarcinoma of colon	193	1.546866	0.0252770	0.0176865
umls:C0151779	Cutaneous Melanoma	217	1.544101	0.0167243	0.0117021
umls:C0220633	Uveal melanoma	165	1.542561	0.0252770	0.0176865
umls:C0011633	Dermatomyositis	88	1.542280	0.0471454	0.0329879
umls:C0566602	Primary sclerosing cholangitis	81	1.539694	0.0471454	0.0329879
umls:C0007785	Cerebral Infarction	248	1.536002	0.0167243	0.0117021
umls:C0008479	Chondrosarcoma	194	1.535331	0.0252770	0.0176865
umls:C0281361	Adenocarcinoma of pancreas	252	1.534429	0.0167243	0.0117021
umls:C0020445	Hypercholesterolemia, Familial	132	1.534149	0.0471454	0.0329879
umls:C0005699	Blast Phase	183	1.533777	0.0252770	0.0176865
umls:C0030354	Papilloma	133	1.531579	0.0411477	0.0287912
umls:C0751396	Well Differentiated Oligodendroglioma	152	1.530093	0.0411477	0.0287912
umls:C0521158	Recurrent tumor	251	1.526603	0.0167243	0.0117021
umls:C0028945	oligodendroglioma	170	1.522911	0.0252770	0.0176865
umls:C1519680	Tumor Immunity	74	1.518855	0.0471454	0.0329879
umls:C0020456	Hyperglycemia	380	1.517361	0.0167243	0.0117021
umls:C3203102	Idiopathic pulmonary arterial hypertension	76	1.517151	0.0411477	0.0287912
umls:C0677932	Progressive Neoplastic Disease	124	1.516668	0.0471454	0.0329879
umls:C3539781	Progressive cGVHD	124	1.516668	0.0471454	0.0329879
umls:C0010823	Cytomegalovirus Infections	133	1.516011	0.0471454	0.0329879
umls:C0029456	Osteoporosis	368	1.515713	0.0167243	0.0117021
umls:C1861172	Venous Thromboembolism	108	1.514747	0.0471454	0.0329879
umls:C1519689	Tumor Promotion	79	1.513661	0.0471454	0.0329879
umls:C0023470	Myeloid Leukemia	430	1.511598	0.0167243	0.0117021
umls:C0242339	Dyslipidemias	187	1.511420	0.0252770	0.0176865
umls:C0033860	Psoriasis	481	1.510789	0.0167243	0.0117021
umls:C0007786	Brain Ischemia	357	1.509625	0.0167243	0.0117021
umls:C0333983	Hyperplastic Polyp	78	1.509326	0.0471454	0.0329879
umls:C0035078	Kidney Failure	268	1.509212	0.0167243	0.0117021
umls:C0151744	Myocardial Ischemia	412	1.507206	0.0167243	0.0117021
umls:C0243026	Sepsis	440	1.507135	0.0167243	0.0117021
umls:C0271650	Impaired glucose tolerance	235	1.505848	0.0167243	0.0117021
umls:C0023448	Lymphoid leukemia	195	1.505600	0.0252770	0.0176865
umls:C0086692	Benign Neoplasm	170	1.504205	0.0411477	0.0287912
umls:C0002871	Anemia	247	1.497204	0.0167243	0.0117021
umls:C1709246	Non-Neoplastic Disorder	374	1.491041	0.0167243	0.0117021
umls:C0856169	Endothelial dysfunction	182	1.487779	0.0471454	0.0329879
umls:C0029928	Ovarian Diseases	180	1.483842	0.0471454	0.0329879
umls:C0032580	Adenomatous Polyposis Coli	324	1.481725	0.0167243	0.0117021
umls:C0206624	Hepatoblastoma	178	1.478142	0.0471454	0.0329879
umls:C0685938	Malignant neoplasm of gastrointestinal tract	182	1.477487	0.0471454	0.0329879
umls:C1516170	Cancer Cell Growth	277	1.473205	0.0252770	0.0176865
umls:C0025149	Medulloblastoma	462	1.470612	0.0167243	0.0117021
umls:C0018671	Head and Neck Neoplasms	292	1.470018	0.0167243	0.0117021
umls:C0079773	Lymphoma, T-Cell, Cutaneous	185	1.463852	0.0471454	0.0329879
umls:C0812413	Malignant Pleural Mesothelioma	200	1.461323	0.0252770	0.0176865
umls:C0007113	Rectal Carcinoma	221	1.458939	0.0252770	0.0176865
umls:C0023452	Leukemia, Lymphocytic, Acute, L1	306	1.457041	0.0167243	0.0117021
umls:C0027022	Myeloproliferative disease	216	1.454890	0.0167243	0.0117021
umls:C0155626	Acute myocardial infarction	186	1.453952	0.0471454	0.0329879
umls:C1704272	Benign Prostatic Hyperplasia	301	1.452728	0.0167243	0.0117021
umls:C2145472	Urothelial Carcinoma	175	1.452684	0.0471454	0.0329879
umls:C0375023	Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site	194	1.447951	0.0252770	0.0176865
umls:C0040136	Thyroid Neoplasm	397	1.446689	0.0252770	0.0176865
umls:C0027708	Nephroblastoma	265	1.444237	0.0167243	0.0117021
umls:C0334634	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	261	1.441078	0.0167243	0.0117021
umls:C3469521	FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	189	1.438611	0.0471454	0.0329879
umls:C0032019	Pituitary Neoplasms	237	1.433424	0.0252770	0.0176865
umls:C0032584	polyps	206	1.429628	0.0252770	0.0176865
umls:C0035309	Retinal Diseases	289	1.423465	0.0167243	0.0117021
umls:C0022665	Kidney Neoplasm	258	1.420942	0.0167243	0.0117021
umls:C1520166	Xenograft Model	440	1.413595	0.0252770	0.0176865
umls:C1302401	Adenoma of large intestine	207	1.410496	0.0339297	0.0237407
umls:C0011853	Diabetes Mellitus, Experimental	422	1.403252	0.0252770	0.0176865
umls:C0085669	Acute leukemia	398	1.391983	0.0398840	0.0279070
umls:C2937358	Cerebral Hemorrhage	207	1.375771	0.0470951	0.0329527
umls:C0041296	Tuberculosis	427	1.372973	0.0252770	0.0176865
umls:C0036690	Septicemia	304	1.362101	0.0252770	0.0176865
umls:C0035335	Retinoblastoma	388	1.341589	0.0465136	0.0325458

Enriched terms for module #EE8045 (MTcor = 0.93)

ID	Description	setSize	NES	p.adjust	qvalues
umls:C2986658	Diffuse Intrinsic Pontine Glioma	19	2.477416	0.0213829	0.0157834
umls:C3495559	Juvenile arthritis	272	2.378926	0.0213200	0.0157370
umls:C0595936	Aqueous Humor Disorders	54	2.334878	0.0213200	0.0157370
umls:C0006274	Bronchiolitis, Viral	139	2.289616	0.0213200	0.0157370
umls:C0004623	Bacterial Infections	180	2.272615	0.0213200	0.0157370
umls:C0151650	Renal fibrosis	143	2.231256	0.0213200	0.0157370
umls:C1527311	Brain Edema	43	2.191929	0.0213200	0.0157370
umls:C3714514	Infection	464	2.190516	0.0213200	0.0157370
umls:C0856825	Acute GVH disease	90	2.164842	0.0213200	0.0157370
umls:C0036202	Sarcoidosis	195	2.148506	0.0213200	0.0157370
umls:C0015944	Fetal Membranes, Premature Rupture	155	2.147448	0.0213200	0.0157370
umls:C0238288	Muscular Dystrophy, Facioscapulohumeral	60	2.143640	0.0213200	0.0157370
umls:C0240035	Interstitial fibrosis	82	2.132722	0.0213200	0.0157370
umls:C0008495	Chorioamnionitis	156	2.131669	0.0213200	0.0157370
umls:C0027697	Nephritis	117	2.126371	0.0213200	0.0157370
umls:C0085437	Meningitis, Bacterial	32	2.123222	0.0213200	0.0157370
umls:C0278504	Non-small cell lung cancer stage I	61	2.122751	0.0213200	0.0157370
umls:C2004493	Leukemia, B-Cell	77	2.122223	0.0213200	0.0157370
umls:C0041956	Ureteral obstruction	120	2.121561	0.0213200	0.0157370
umls:C0031099	Periodontitis	198	2.106942	0.0213200	0.0157370
umls:C0036421	Systemic Scleroderma	441	2.102414	0.0213200	0.0157370
umls:C2919032	Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified	149	2.101503	0.0213200	0.0157370
umls:C0032964	Pregnancy Complications, Hematologic	108	2.101098	0.0213200	0.0157370
umls:C0038395	Streptococcal Infections	35	2.095752	0.0213200	0.0157370
umls:C0036117	Salmonella infections	23	2.091344	0.0213200	0.0157370
umls:C0026857	Musculoskeletal Diseases	107	2.090082	0.0213200	0.0157370
umls:C0016059	Fibrosis	163	2.089532	0.0213200	0.0157370
umls:C0333307	Superficial ulcer	98	2.087237	0.0213200	0.0157370
umls:C0035235	Respiratory Syncytial Virus Infections	217	2.076661	0.0213200	0.0157370
umls:C0015929	Fetal Diseases	122	2.075651	0.0213200	0.0157370
umls:C1800706	Idiopathic Pulmonary Fibrosis	276	2.070348	0.0213200	0.0157370
umls:C0025568	Metaplasia	62	2.064722	0.0213200	0.0157370
umls:C0035455	Rhinitis	71	2.059612	0.0213200	0.0157370
umls:C0020517	Hypersensitivity	121	2.056660	0.0213200	0.0157370
umls:C0333186	Restenosis	169	2.056332	0.0213200	0.0157370
umls:C0039128	Syphilis	18	2.055331	0.0213200	0.0157370
umls:C0034067	Pulmonary Emphysema	153	2.048690	0.0213200	0.0157370
umls:C1636667	Disorder characterized by eosinophilia	95	2.048537	0.0213200	0.0157370
umls:C0014457	Eosinophilia	102	2.046762	0.0213200	0.0157370
umls:C0242488	Acute Lung Injury	57	2.043495	0.0311509	0.0229935
umls:C0162810	Cicatrix, Hypertrophic	51	2.041923	0.0213200	0.0157370
umls:C0850639	premalignant lesion	19	2.041144	0.0213829	0.0157834
umls:C0032285	Pneumonia	312	2.040063	0.0213200	0.0157370
umls:C0022876	Premature Obstetric Labor	163	2.039189	0.0213200	0.0157370
umls:C0332853	Anastomosis	18	2.037882	0.0213200	0.0157370
umls:C3714757	Juvenile rheumatoid arthritis	139	2.036202	0.0213200	0.0157370
umls:C1306759	Eosinophilic disorder	96	2.035730	0.0213200	0.0157370
umls:C0024291	Lymphohistiocytosis, Hemophagocytic	69	2.029287	0.0213200	0.0157370
umls:C0600518	Choroidal Neovascularization	43	2.027076	0.0213200	0.0157370
umls:C1292758	Precursor T-cell lymphoblastic lymphoma	12	2.021305	0.0216080	0.0159496
umls:C0009319	Colitis	414	2.019691	0.0213200	0.0157370
umls:C0023241	Legionnaires’ Disease	12	2.007745	0.0216080	0.0159496
umls:C0374997	Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site	246	2.004850	0.0213200	0.0157370
umls:C0162871	Aortic Aneurysm, Abdominal	151	2.004158	0.0213200	0.0157370
umls:C0206659	Embryonal Carcinoma	128	2.004111	0.0213200	0.0157370
umls:C0024115	Lung diseases	276	2.000453	0.0213200	0.0157370
umls:C0001339	Acute pancreatitis	70	1.995536	0.0213200	0.0157370
umls:C1719672	Severe Sepsis	66	1.994544	0.0213200	0.0157370
umls:C0032914	Pre-Eclampsia	275	1.989170	0.0213200	0.0157370
umls:C0029410	Osteoarthritis of hip	53	1.988582	0.0213200	0.0157370
umls:C0085129	Bronchial Hyperreactivity	128	1.988006	0.0213200	0.0157370
umls:C0879615	Stromal Neoplasm	70	1.987804	0.0213200	0.0157370
umls:C0079218	Fibromatosis, Aggressive	53	1.987539	0.0213200	0.0157370
umls:C0153690	Secondary malignant neoplasm of bone	233	1.982889	0.0213200	0.0157370
umls:C0019829	Hodgkin Disease	306	1.982287	0.0213200	0.0157370
umls:C0079588	Ichthyosis, X-Linked	70	1.978848	0.0213200	0.0157370
umls:C0023343	Leprosy	105	1.978436	0.0213200	0.0157370
umls:C0235989	Renal interstitial fibrosis	29	1.976910	0.0311509	0.0229935
umls:C0151526	Premature Birth	235	1.972550	0.0213200	0.0157370
umls:C0011603	Dermatitis	126	1.968657	0.0213200	0.0157370
umls:C2607914	Allergic rhinitis (disorder)	120	1.966879	0.0213200	0.0157370
umls:C0149939	Obstructive nephropathy	33	1.964525	0.0213200	0.0157370
umls:C0018824	Heart valve disease	38	1.964080	0.0213200	0.0157370
umls:C0035222	Respiratory Distress Syndrome, Adult	113	1.963345	0.0213200	0.0157370
umls:C0263454	Chloracne	36	1.959919	0.0213200	0.0157370
umls:C0013537	Eclampsia	143	1.957980	0.0213200	0.0157370
umls:C0477474	Dermatitis and eczema	23	1.952579	0.0213200	0.0157370
umls:C0026654	Moyamoya Disease	34	1.952175	0.0311509	0.0229935
umls:C0042165	Anterior uveitis	28	1.951839	0.0213200	0.0157370
umls:C0032965	Pregnancy Complications, Infectious	24	1.950603	0.0213200	0.0157370
umls:C0494261	Combined immunodeficiency	22	1.948691	0.0213829	0.0157834
umls:C0398686	Primary immune deficiency disorder	59	1.948441	0.0311509	0.0229935
umls:C0043144	Wheezing	50	1.947701	0.0311509	0.0229935
umls:C0024143	Lupus Nephritis	161	1.939364	0.0213200	0.0157370
umls:C0017658	Glomerulonephritis	161	1.935815	0.0213200	0.0157370
umls:C0019189	Hepatitis, Chronic	138	1.935481	0.0213200	0.0157370
umls:C0340629	Aortic aneurysm without mention of rupture NOS	26	1.929815	0.0213200	0.0157370
umls:C1261287	Stenosis	26	1.928441	0.0213200	0.0157370
umls:C0003507	Aortic Valve Stenosis	72	1.927683	0.0213200	0.0157370
umls:C1333064	Classical Hodgkin’s Lymphoma	100	1.925577	0.0213200	0.0157370
umls:C0024305	Lymphoma, Non-Hodgkin	426	1.923015	0.0213200	0.0157370
umls:C1290884	Inflammatory disorder	183	1.922539	0.0213200	0.0157370
umls:C0003864	Arthritis	427	1.921011	0.0213200	0.0157370
umls:C0019340	Herpes NOS	67	1.920709	0.0213200	0.0157370
umls:C0034040	Puerperal Disorders	27	1.918742	0.0311509	0.0229935
umls:C0262655	Recurrent urinary tract infection	10	1.918535	0.0218867	0.0161553
umls:C0018133	Graft-vs-Host Disease	230	1.917069	0.0213200	0.0157370
umls:C0079487	Helicobacter Infections	81	1.916418	0.0213200	0.0157370
umls:C0030848	Peyronie Disease	14	1.913279	0.0214913	0.0158635
umls:C0042373	Vascular Diseases	328	1.910150	0.0213200	0.0157370
umls:C0206180	Ki-1+ Anaplastic Large Cell Lymphoma	214	1.909894	0.0213200	0.0157370
umls:C1290886	Chronic inflammatory disorder	59	1.906638	0.0311509	0.0229935
umls:C0034069	Pulmonary Fibrosis	290	1.904873	0.0213200	0.0157370
umls:C0014356	Enterocolitis	18	1.896437	0.0213200	0.0157370
umls:C0007282	Carotid Stenosis	95	1.895396	0.0213200	0.0157370
umls:C0004030	Aspergillosis	21	1.894287	0.0315451	0.0232845
umls:C0035457	Rhinitis, Allergic, Perennial	26	1.891891	0.0314450	0.0232106
umls:C0042487	Venous Thrombosis	75	1.891424	0.0213200	0.0157370
umls:C0392707	Atopy	42	1.891269	0.0311509	0.0229935
umls:C0085655	Polymyositis	80	1.888914	0.0213200	0.0157370
umls:C0009447	Common Variable Immunodeficiency	91	1.887062	0.0213200	0.0157370
umls:C1368683	Epithelioma	225	1.885352	0.0213200	0.0157370
umls:C0003486	Aortic Aneurysm	167	1.885293	0.0213200	0.0157370
umls:C0162820	Dermatitis, Allergic Contact	83	1.885115	0.0213200	0.0157370
umls:C0266929	Chronic Periodontitis	127	1.882263	0.0213200	0.0157370
umls:C0006272	Bronchiolitis Obliterans	40	1.881308	0.0311509	0.0229935
umls:C0751967	Multiple Sclerosis, Relapsing-Remitting	77	1.880040	0.0213200	0.0157370
umls:C0031090	Periodontal Diseases	94	1.879043	0.0213200	0.0157370
umls:C0019100	Severe Dengue	59	1.875929	0.0311509	0.0229935
umls:C1527336	Sjogren’s Syndrome	88	1.875917	0.0213200	0.0157370
umls:C0022548	Keloid	146	1.875774	0.0213200	0.0157370
umls:C0740903	allergic symptom	12	1.875239	0.0216080	0.0159496
umls:C0920646	Renal ischaemia	76	1.874924	0.0213200	0.0157370
umls:C0019061	Hemolytic-Uremic Syndrome	49	1.874393	0.0311509	0.0229935
umls:C0340288	Stable angina	66	1.873044	0.0213200	0.0157370
umls:C0011615	Dermatitis, Atopic	333	1.867401	0.0213200	0.0157370
umls:C0153252	Systemic candidiasis	33	1.866710	0.0405803	0.0299536
umls:C0019187	Hepatitis, Alcoholic	41	1.865726	0.0405803	0.0299536
umls:C3539909	Allergic disposition	149	1.865306	0.0213200	0.0157370
umls:C0014170	Endometrial Neoplasms	220	1.864897	0.0213200	0.0157370
umls:C0035369	Retroviridae Infections	54	1.864806	0.0405803	0.0299536
umls:C0021345	Infectious Mononucleosis	22	1.863938	0.0315692	0.0233023
umls:C0014072	Experimental Autoimmune Encephalomyelitis	305	1.862708	0.0213200	0.0157370
umls:C0206139	Lichen Planus, Oral	64	1.861166	0.0311509	0.0229935
umls:C0017411	Female Genital Diseases	14	1.859859	0.0318390	0.0235014
umls:C0004943	Behcet Syndrome	229	1.859711	0.0213200	0.0157370
umls:C1561535	Creatinine finding	74	1.858689	0.0311509	0.0229935
umls:C1801959	Histiocytic medullary reticulosis (disorder)	12	1.858365	0.0216080	0.0159496
umls:C0020523	Immediate hypersensitivity	87	1.857445	0.0213200	0.0157370
umls:C0079773	Lymphoma, T-Cell, Cutaneous	185	1.857153	0.0213200	0.0157370
umls:C0024232	Lymphatic Metastasis	133	1.853178	0.0213200	0.0157370
umls:C0993582	Arthritis, Experimental	133	1.852319	0.0213200	0.0157370
umls:C0007570	Celiac Disease	268	1.852155	0.0213200	0.0157370
umls:C0023465	Acute monocytic leukemia	64	1.851873	0.0311509	0.0229935
umls:C0042798	Low Vision	19	1.850846	0.0317037	0.0234016
umls:C0026946	Mycoses	193	1.849987	0.0213200	0.0157370
umls:C0376545	Hematologic Neoplasms	399	1.846868	0.0213200	0.0157370
umls:C0034065	Pulmonary Embolism	54	1.846421	0.0405803	0.0299536
umls:C0037199	Sinusitis	29	1.846386	0.0405803	0.0299536
umls:C0002382	Alveolar Bone Loss	26	1.845689	0.0314450	0.0232106
umls:C0020608	Hypodontia	18	1.845416	0.0315216	0.0232671
umls:C0153676	Secondary malignant neoplasm of lung	490	1.842982	0.0213200	0.0157370
umls:C0031106	Periodontitis, Juvenile	69	1.841787	0.0213200	0.0157370
umls:C0029883	Otitis Media with Effusion	17	1.841379	0.0413542	0.0305249
umls:C0085435	Arthritis, Reactive	38	1.841341	0.0405803	0.0299536
umls:C1096184	West Nile viral infection	64	1.841339	0.0405803	0.0299536
umls:C0242647	Mucosa-Associated Lymphoid Tissue Lymphoma	142	1.840017	0.0213200	0.0157370
umls:C0206677	Adenomatous Polyps	58	1.836225	0.0405803	0.0299536
umls:C1306889	Peripheral arterial occlusive disease	14	1.836155	0.0318390	0.0235014
umls:C0856053	Leukemia secondary	17	1.834491	0.0413542	0.0305249
umls:C0029899	Otosclerosis	15	1.834298	0.0214913	0.0158635
umls:C0701807	Acute anterior uveitis	33	1.832306	0.0405803	0.0299536
umls:C0019158	Hepatitis	196	1.831492	0.0213200	0.0157370
umls:C0175701	Aarskog syndrome	12	1.831353	0.0216080	0.0159496
umls:C0029172	Oral Submucous Fibrosis	45	1.831225	0.0311509	0.0229935
umls:C1318544	M5b Acute differentiated monocytic leukemia	73	1.830951	0.0213200	0.0157370
umls:C0079772	T-Cell Lymphoma	239	1.830325	0.0213200	0.0157370
umls:C0273115	Lung Injury	26	1.830009	0.0314450	0.0232106
umls:C0007766	Intracranial Aneurysm	96	1.829716	0.0213200	0.0157370
umls:C3714636	Pneumonitis	46	1.829014	0.0311509	0.0229935
umls:C0409959	Osteoarthritis, Knee	94	1.828574	0.0213200	0.0157370
umls:C0025229	Melioidosis	23	1.828572	0.0412888	0.0304767
umls:C1511789	Desmoplastic	68	1.827364	0.0213200	0.0157370
umls:C0398650	Immune thrombocytopenic purpura	68	1.825489	0.0311509	0.0229935
umls:C3272363	Ischemic Cerebrovascular Accident	271	1.824877	0.0213200	0.0157370
umls:C1332977	Childhood Leukemia	51	1.823810	0.0405803	0.0299536
umls:C0002351	Altitude Sickness	16	1.823373	0.0413542	0.0305249
umls:C0206694	Mucoepidermoid Carcinoma	59	1.822096	0.0405803	0.0299536
umls:C0085786	Hamman-Rich syndrome	29	1.816735	0.0405803	0.0299536
umls:C0023267	Fibroid Tumor	270	1.815043	0.0213200	0.0157370
umls:C0006840	Candidiasis	66	1.813852	0.0405803	0.0299536
umls:C0001925	Albuminuria	111	1.813335	0.0213200	0.0157370
umls:C0524702	Pulmonary Thromboembolisms	14	1.807108	0.0318390	0.0235014
umls:C0037274	Dermatologic disorders	363	1.806392	0.0213200	0.0157370
umls:C1519680	Tumor Immunity	74	1.805772	0.0311509	0.0229935
umls:C0877009	Muscle fibrosis	10	1.805284	0.0430706	0.0317919
umls:C0032787	Postoperative Complications	48	1.804926	0.0405803	0.0299536
umls:C0006413	Burkitt Lymphoma	167	1.802105	0.0213200	0.0157370
umls:C0340708	Deep vein thrombosis of lower limb	37	1.801789	0.0405803	0.0299536
umls:C1449563	Cardiomyopathy, Familial Idiopathic	159	1.800570	0.0213200	0.0157370
umls:C0019080	Hemorrhage	54	1.798345	0.0483787	0.0357099
umls:C0019069	Hemophilia A	73	1.798157	0.0311509	0.0229935
umls:C0009782	Connective Tissue Diseases	159	1.797990	0.0213200	0.0157370
umls:C1854310	Hypotrichosis simplex	15	1.797742	0.0416191	0.0307204
umls:C0431350	Primary microcephaly	17	1.797715	0.0489743	0.0361495
umls:C0020875	Ileal Diseases	16	1.797385	0.0489743	0.0361495
umls:C0023895	Liver diseases	446	1.797311	0.0213200	0.0157370
umls:C0524909	Hepatitis B, Chronic	185	1.797022	0.0213200	0.0157370
umls:C0206708	Cervical Intraepithelial Neoplasia	179	1.796918	0.0213200	0.0157370
umls:C0238394	Female Pseudohermaphroditism	43	1.796287	0.0482231	0.0355951
umls:C0036420	Localized scleroderma	19	1.795950	0.0414729	0.0306125
umls:C0035328	Retinal Vein Occlusion	24	1.795946	0.0314450	0.0232106
umls:C0013238	Dry Eye Syndromes	36	1.795804	0.0405803	0.0299536
umls:C0340643	Dissection of aorta	31	1.795056	0.0405803	0.0299536
umls:C0948008	Ischemic stroke	307	1.794768	0.0213200	0.0157370
umls:C0154084	Stage 0 Breast Carcinoma	13	1.794622	0.0418166	0.0308662
umls:C0008312	Primary biliary cirrhosis	201	1.794573	0.0213200	0.0157370
umls:C0030305	Pancreatitis	149	1.793622	0.0213200	0.0157370
umls:C0031154	Peritonitis	88	1.791978	0.0213200	0.0157370
umls:C0024312	Lymphopenia	60	1.791713	0.0405803	0.0299536
umls:C0178238	Intestinal infectious disease (disorder)	12	1.789844	0.0498646	0.0368067
umls:C0017152	Gastritis	153	1.789086	0.0213200	0.0157370
umls:C0376620	Pouchitis	12	1.788864	0.0498646	0.0368067
umls:C0242966	Systemic Inflammatory Response Syndrome	54	1.787890	0.0483787	0.0357099
umls:C0021051	Immunologic Deficiency Syndromes	349	1.787888	0.0213200	0.0157370
umls:C0029118	Opportunistic Infections	25	1.787602	0.0489743	0.0361495
umls:C0156181	Peritoneal adhesion	12	1.786238	0.0498646	0.0368067
umls:C0003872	Arthritis, Psoriatic	140	1.785486	0.0213200	0.0157370
umls:C0585362	Squamous cell carcinoma of mouth	42	1.784861	0.0405803	0.0299536
umls:C0013884	Filarial Elephantiases	16	1.784540	0.0489743	0.0361495
umls:C0162872	Aortic Aneurysm, Thoracic	91	1.784278	0.0213200	0.0157370
umls:C0023892	Biliary cirrhosis	100	1.782895	0.0213200	0.0157370
umls:C0017563	Gingival Diseases	74	1.782359	0.0311509	0.0229935
umls:C0029458	Osteoporosis, Postmenopausal	74	1.781473	0.0311509	0.0229935
umls:C1719495	Aggressive periodontitis, generalized	29	1.781152	0.0405803	0.0299536
umls:C0345967	Malignant mesothelioma	227	1.778173	0.0213200	0.0157370
umls:C0013312	Dupuytren Contracture	16	1.777424	0.0489743	0.0361495
umls:C0085390	Li-Fraumeni Syndrome	37	1.777215	0.0483787	0.0357099
umls:C0020217	Hydatidiform Mole	48	1.776973	0.0405803	0.0299536
umls:C0038013	Ankylosing spondylitis	187	1.776612	0.0213200	0.0157370
umls:C0007114	Malignant neoplasm of skin	192	1.776078	0.0213200	0.0157370
umls:C0850666	Helicobacter pylori infection	225	1.774730	0.0213200	0.0157370
umls:C0035126	Reperfusion Injury	271	1.774648	0.0213200	0.0157370
umls:C0040053	Thrombosis	105	1.773576	0.0213200	0.0157370
umls:C0010606	Adenoid Cystic Carcinoma	185	1.773300	0.0213200	0.0157370
umls:C0008149	Chlamydia Infections	61	1.772866	0.0405803	0.0299536
umls:C0080233	Tooth Loss	14	1.772439	0.0495858	0.0366009
umls:C3662483	Allergic sensitization	29	1.771174	0.0405803	0.0299536
umls:C1402294	Primary Lesion	30	1.771110	0.0405803	0.0299536
umls:C0699949	airway disease	64	1.769208	0.0405803	0.0299536
umls:C0278996	Cancer of Head and Neck	361	1.766759	0.0213200	0.0157370
umls:C0008497	Choriocarcinoma	226	1.764559	0.0213200	0.0157370
umls:C1848411	XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP E	13	1.764103	0.0495858	0.0366009
umls:C0149516	Chronic sinusitis	42	1.760737	0.0482231	0.0355951
umls:C3150911	GASTRIC CANCER, INTESTINAL	12	1.759898	0.0498646	0.0368067
umls:C0001486	Adenovirus Infections	63	1.759357	0.0405803	0.0299536
umls:C0079744	Diffuse Large B-Cell Lymphoma	459	1.757885	0.0213200	0.0157370
umls:C0971858	Arthritis, Collagen-Induced	133	1.756517	0.0213200	0.0157370
umls:C1559271	Non-Malignant Ascites Adverse Event	146	1.756292	0.0213200	0.0157370
umls:C1176475	Ductal Carcinoma	185	1.755945	0.0213200	0.0157370
umls:C1956391	Temporal Arteritis	13	1.755570	0.0495858	0.0366009
umls:C0011119	Decompression Sickness	13	1.755079	0.0495858	0.0366009
umls:C0694549	Community acquired pneumonia	29	1.753912	0.0482231	0.0355951
umls:C1292769	Precursor B-cell lymphoblastic leukemia	297	1.753829	0.0213200	0.0157370
umls:C0013595	Eczema	281	1.753064	0.0213200	0.0157370
umls:C0018213	Graves Disease	260	1.751967	0.0213200	0.0157370
umls:C0948089	Acute Coronary Syndrome	241	1.750868	0.0213200	0.0157370
umls:C0409651	Seropositive rheumatoid arthritis	16	1.749657	0.0489743	0.0361495
umls:C0149678	Epstein-Barr Virus Infections	174	1.749288	0.0213200	0.0157370
umls:C0278701	Gastric Adenocarcinoma	216	1.748453	0.0213200	0.0157370
umls:C0276680	Infection by Candida albicans	15	1.748193	0.0495578	0.0365803
umls:C0019159	Hepatitis A	188	1.747388	0.0213200	0.0157370
umls:C0017612	Glaucoma, Open-Angle	77	1.746690	0.0311509	0.0229935
umls:C0242706	Hyperoxia	42	1.746291	0.0482231	0.0355951
umls:C0399440	Hereditary gingival fibromatosis	17	1.745732	0.0489743	0.0361495
umls:C0024131	Lupus Vulgaris	238	1.744443	0.0213200	0.0157370
umls:C0033687	Proteinuria	67	1.744372	0.0482231	0.0355951
umls:C1519670	Tumor Angiogenesis	360	1.743868	0.0213200	0.0157370
umls:C0853879	Invasive breast carcinoma	321	1.742790	0.0213200	0.0157370
umls:C0023290	Leishmaniasis, Visceral	58	1.740428	0.0482231	0.0355951
umls:C1561643	Chronic Kidney Diseases	229	1.740151	0.0213200	0.0157370
umls:C0023470	Myeloid Leukemia	430	1.740125	0.0213200	0.0157370
umls:C0409974	Lupus Erythematosus	284	1.739497	0.0213200	0.0157370
umls:C0011616	Contact Dermatitis	62	1.739032	0.0405803	0.0299536
umls:C0023893	Liver Cirrhosis, Experimental	149	1.737959	0.0213200	0.0157370
umls:C0376544	Hematopoietic Neoplasms	140	1.735318	0.0213200	0.0157370
umls:C1621958	Glioblastoma Multiforme	370	1.734290	0.0213200	0.0157370
umls:C0220810	Congenital defects	43	1.733045	0.0482231	0.0355951
umls:C0149521	Pancreatitis, Chronic	214	1.732374	0.0213200	0.0157370
umls:C0027439	Nasopharyngeal Neoplasms	61	1.732158	0.0405803	0.0299536
umls:C0000786	Spontaneous abortion	191	1.730129	0.0213200	0.0157370
umls:C0079745	Lymphoma, Large-Cell, Follicular	137	1.729920	0.0213200	0.0157370
umls:C0011633	Dermatomyositis	88	1.728514	0.0213200	0.0157370
umls:C0002940	Aneurysm	107	1.728356	0.0213200	0.0157370
umls:C0005411	Biliary Atresia	69	1.725914	0.0482231	0.0355951
umls:C2945695	Limb ischemia	57	1.725085	0.0482231	0.0355951
umls:C0017185	Gastrointestinal Neoplasms	102	1.723935	0.0311509	0.0229935
umls:C0403447	Chronic Kidney Insufficiency	149	1.723352	0.0213200	0.0157370
umls:C1378703	Renal carcinoma	387	1.721292	0.0213200	0.0157370
umls:C0018273	Growth Disorders	64	1.720907	0.0405803	0.0299536
umls:C0027626	Neoplasm Invasiveness	147	1.719976	0.0213200	0.0157370
umls:C0006663	Calcinosis	82	1.719791	0.0311509	0.0229935
umls:C0036920	Sezary Syndrome	109	1.718321	0.0213200	0.0157370
umls:C0038358	Gastric ulcer	87	1.717007	0.0213200	0.0157370
umls:C0002793	Anaplasia	191	1.716325	0.0213200	0.0157370
umls:C0003130	Anoxia	306	1.716101	0.0213200	0.0157370
umls:C0026896	Myasthenia Gravis	139	1.714579	0.0213200	0.0157370
umls:C0346153	Breast Cancer, Familial	127	1.713297	0.0213200	0.0157370
umls:C0008313	Cholangitis, Sclerosing	69	1.711042	0.0482231	0.0355951
umls:C3542024	AORTIC VALVE DISEASE 2	52	1.710445	0.0482231	0.0355951
umls:C1334274	Invasive Carcinoma	134	1.709532	0.0213200	0.0157370
umls:C0023452	Leukemia, Lymphocytic, Acute, L1	306	1.709137	0.0213200	0.0157370
umls:C0029456	Osteoporosis	368	1.709073	0.0213200	0.0157370
umls:C0027430	Nasal Polyps	141	1.707847	0.0213200	0.0157370
umls:C0278883	Metastatic melanoma	272	1.707684	0.0213200	0.0157370
umls:C0042029	Urinary tract infection	64	1.707610	0.0482231	0.0355951
umls:C0021053	Immune System Diseases	142	1.706016	0.0213200	0.0157370
umls:C0023448	Lymphoid leukemia	195	1.705062	0.0213200	0.0157370
umls:C1861172	Venous Thromboembolism	108	1.703912	0.0213200	0.0157370
umls:C0220641	Lip and Oral Cavity Carcinoma	344	1.702619	0.0213200	0.0157370
umls:C0339573	Glaucoma, Primary Open Angle	141	1.701075	0.0213200	0.0157370
umls:C0153381	Malignant neoplasm of mouth	344	1.700469	0.0213200	0.0157370
umls:C0243038	Carcinoma, Lewis Lung	67	1.700457	0.0482231	0.0355951
umls:C0279628	Adenocarcinoma Of Esophagus	229	1.698785	0.0213200	0.0157370
umls:C0018203	Chronic granulomatous disease	60	1.697427	0.0482231	0.0355951
umls:C0349566	Squamous cell carcinoma of tongue	98	1.697011	0.0213200	0.0157370
umls:C0023485	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	87	1.696231	0.0311509	0.0229935
umls:C0577631	Carotid Atherosclerosis	88	1.695058	0.0311509	0.0229935
umls:C0011644	Scleroderma	132	1.694061	0.0213200	0.0157370
umls:C0524910	Hepatitis C, Chronic	327	1.693594	0.0213200	0.0157370
umls:C0027726	Nephrotic Syndrome	144	1.690701	0.0213200	0.0157370
umls:C0023493	Adult T-Cell Lymphoma/Leukemia	366	1.689828	0.0213200	0.0157370
umls:C0039103	Synovitis	76	1.688400	0.0482231	0.0355951
umls:C0035435	Rheumatism	86	1.686457	0.0311509	0.0229935
umls:C0017525	Giant Cell Tumors	63	1.686411	0.0405803	0.0299536
umls:C0042384	Vasculitis	105	1.684148	0.0311509	0.0229935
umls:C0085110	Severe Combined Immunodeficiency	420	1.681789	0.0213200	0.0157370
umls:C0027055	Myocardial Reperfusion Injury	132	1.678653	0.0213200	0.0157370
umls:C1762616	Meningioma, benign, no ICD-O subtype	191	1.677007	0.0213200	0.0157370
umls:C0239946	Fibrosis, Liver	271	1.676727	0.0213200	0.0157370
umls:C0007124	Noninfiltrating Intraductal Carcinoma	257	1.676222	0.0213200	0.0157370
umls:C0042164	Uveitis	100	1.672861	0.0311509	0.0229935
umls:C0021841	Intestinal Neoplasms	121	1.670811	0.0213200	0.0157370
umls:C0025007	Measles	120	1.670755	0.0213200	0.0157370
umls:C1840264	IMMUNE SUPPRESSION	61	1.669468	0.0405803	0.0299536
umls:C0031069	Familial Mediterranean Fever	59	1.666993	0.0482231	0.0355951
umls:C0949691	Spondylarthropathies	65	1.664208	0.0482231	0.0355951
umls:C0024138	Lupus Erythematosus, Discoid	244	1.659966	0.0213200	0.0157370
umls:C0346429	Multiple malignancy	164	1.655313	0.0213200	0.0157370
umls:C0042133	Uterine Fibroids	276	1.652778	0.0213200	0.0157370
umls:C0027686	Pathologic Neovascularization	62	1.645218	0.0482231	0.0355951
umls:C0280324	Laryngeal Squamous Cell Carcinoma	110	1.643851	0.0311509	0.0229935
umls:C0940937	precancerous lesions	91	1.643798	0.0482231	0.0355951
umls:C0022578	Keratoconus	66	1.640926	0.0482231	0.0355951
umls:C0206698	Cholangiocarcinoma	333	1.637698	0.0213200	0.0157370
umls:C0034063	Pulmonary Edema	66	1.635592	0.0482231	0.0355951
umls:C0022680	Polycystic Kidney Diseases	100	1.635009	0.0405803	0.0299536
umls:C1333990	Hereditary Nonpolyposis Colorectal Cancer	100	1.632791	0.0405803	0.0299536
umls:C0020542	Pulmonary Hypertension	283	1.629915	0.0213200	0.0157370
umls:C0008924	Cleft Lip	173	1.629457	0.0213200	0.0157370
umls:C0005695	Bladder Neoplasm	390	1.628503	0.0213200	0.0157370
umls:C0341439	Chronic liver disease	108	1.624461	0.0311509	0.0229935
umls:C0035412	Rhabdomyosarcoma	307	1.623145	0.0213200	0.0157370
umls:C0019348	Herpes Simplex Infections	425	1.619254	0.0213200	0.0157370
umls:C0023524	Leukoencephalopathy, Progressive Multifocal	84	1.617181	0.0482231	0.0355951
umls:C0345904	Malignant neoplasm of liver	481	1.617168	0.0213200	0.0157370
umls:C0040028	Thrombocythemia, Essential	124	1.617080	0.0213200	0.0157370
umls:C0020473	Hyperlipidemia	174	1.616695	0.0213200	0.0157370
umls:C0024667	Animal Mammary Neoplasms	178	1.616187	0.0213200	0.0157370
umls:C0026691	Mucocutaneous Lymph Node Syndrome	145	1.614511	0.0213200	0.0157370
umls:C0151744	Myocardial Ischemia	412	1.612866	0.0213200	0.0157370
umls:C0376634	Craniofacial Abnormalities	175	1.606935	0.0213200	0.0157370
umls:C0008925	Cleft Palate	216	1.605817	0.0213200	0.0157370
umls:C0152018	Esophageal carcinoma	445	1.605376	0.0213200	0.0157370
umls:C0025286	Meningioma	381	1.604537	0.0213200	0.0157370
umls:C0041327	Tuberculosis, Pulmonary	170	1.604424	0.0213200	0.0157370
umls:C0020443	Hypercholesterolemia	150	1.602699	0.0213200	0.0157370
umls:C0008626	Congenital chromosomal disease	440	1.602318	0.0213200	0.0157370
umls:C0279000	Liver and Intrahepatic Biliary Tract Carcinoma	403	1.597942	0.0213200	0.0157370
umls:C1961099	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	287	1.597679	0.0213200	0.0157370
umls:C0007103	Malignant neoplasm of endometrium	413	1.595849	0.0213200	0.0157370
umls:C1883486	Uterine Corpus Cancer	413	1.595849	0.0213200	0.0157370
umls:C0011311	Dengue Fever	140	1.595500	0.0311509	0.0229935
umls:C0242596	Neoplasm, Residual	145	1.594286	0.0311509	0.0229935
umls:C0024314	Lymphoproliferative Disorders	167	1.594002	0.0213200	0.0157370
umls:C1623038	Cirrhosis	307	1.592983	0.0213200	0.0157370
umls:C0546837	Malignant neoplasm of esophagus	485	1.592897	0.0213200	0.0157370
umls:C0281361	Adenocarcinoma of pancreas	252	1.588880	0.0213200	0.0157370
umls:C0242383	Age related macular degeneration	331	1.588860	0.0213200	0.0157370
umls:C0022661	Kidney Failure, Chronic	483	1.588260	0.0213200	0.0157370
umls:C0026640	Mouth Neoplasms	173	1.588257	0.0213200	0.0157370
umls:C0334579	Anaplastic astrocytoma	125	1.588124	0.0311509	0.0229935
umls:C0005940	Bone Diseases	137	1.586987	0.0405803	0.0299536
umls:C0018798	Congenital Heart Defects	210	1.586787	0.0311509	0.0229935
umls:C0007621	Neoplastic Cell Transformation	109	1.584165	0.0405803	0.0299536
umls:C0023487	Acute Promyelocytic Leukemia	359	1.581779	0.0213200	0.0157370
umls:C0598608	Hyperhomocysteinemia	98	1.576703	0.0482231	0.0355951
umls:C0007873	Uterine Cervical Neoplasm	146	1.574003	0.0311509	0.0229935
umls:C0007786	Brain Ischemia	357	1.573395	0.0213200	0.0157370
umls:C0243026	Sepsis	440	1.571539	0.0213200	0.0157370
umls:C0375023	Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site	194	1.568765	0.0311509	0.0229935
umls:C0036220	Kaposi Sarcoma	147	1.567461	0.0474230	0.0350045
umls:C0685938	Malignant neoplasm of gastrointestinal tract	182	1.567058	0.0311509	0.0229935
umls:C0085669	Acute leukemia	398	1.564294	0.0213200	0.0157370
umls:C0152171	Idiopathic pulmonary hypertension	181	1.564007	0.0311509	0.0229935
umls:C2316810	Chronic kidney disease stage 5	161	1.561765	0.0213200	0.0157370
umls:C0010674	Cystic Fibrosis	330	1.554634	0.0213200	0.0157370
umls:C0595989	Carcinoma of larynx	146	1.554064	0.0311509	0.0229935
umls:C1134719	Invasive Ductal Breast Carcinoma	205	1.549578	0.0402397	0.0297023
umls:C0338106	Adenocarcinoma of colon	193	1.547574	0.0311509	0.0229935
umls:C0238463	Papillary thyroid carcinoma	379	1.547233	0.0213200	0.0157370
umls:C3539878	Triple Negative Breast Neoplasms	388	1.542960	0.0213200	0.0157370
umls:C0007785	Cerebral Infarction	248	1.542908	0.0213200	0.0157370
umls:C0017601	Glaucoma	180	1.542728	0.0311509	0.0229935
umls:C0279702	Conventional (Clear Cell) Renal Cell Carcinoma	304	1.540463	0.0213200	0.0157370
umls:C0027708	Nephroblastoma	265	1.535806	0.0311509	0.0229935
umls:C1292778	Chronic myeloproliferative disorder	139	1.534717	0.0474230	0.0350045
umls:C0037286	Skin Neoplasms	274	1.534092	0.0213200	0.0157370
umls:C0024301	Lymphoma, Follicular	300	1.532711	0.0213200	0.0157370
umls:C0020445	Hypercholesterolemia, Familial	132	1.532093	0.0474230	0.0350045
umls:C1335302	Pancreatic Ductal Adenocarcinoma	462	1.528290	0.0213200	0.0157370
umls:C0149782	Squamous cell carcinoma of lung	163	1.527618	0.0311509	0.0229935
umls:C1384666	hearing impairment	134	1.524354	0.0475364	0.0350882
umls:C0400966	Non-alcoholic Fatty Liver Disease	243	1.524304	0.0311509	0.0229935
umls:C0917798	Cerebral Ischemia	163	1.519668	0.0311509	0.0229935
umls:C0151779	Cutaneous Melanoma	217	1.518516	0.0311509	0.0229935
umls:C0013336	Dwarfism	161	1.517249	0.0403029	0.0297489
umls:C0008479	Chondrosarcoma	194	1.514752	0.0402700	0.0297247
umls:C1336076	Sporadic Breast Carcinoma	126	1.514103	0.0479176	0.0353696
umls:C0008370	Cholestasis	127	1.513776	0.0475774	0.0351184
umls:C0278488	Carcinoma breast stage IV	280	1.508732	0.0213200	0.0157370
umls:C0023492	Leukemia, T-Cell	270	1.508727	0.0311509	0.0229935
umls:C0032927	Precancerous Conditions	351	1.508117	0.0213200	0.0157370
umls:C0033860	Psoriasis	481	1.498909	0.0213200	0.0157370
umls:C1272641	Systemic arterial pressure	380	1.498210	0.0213200	0.0157370
umls:C0011884	Diabetic Retinopathy	191	1.497532	0.0402546	0.0297132
umls:C0016057	Fibrosarcoma	224	1.495819	0.0213200	0.0157370
umls:C0740457	Malignant neoplasm of kidney	337	1.492967	0.0213200	0.0157370
umls:C0025500	Mesothelioma	326	1.492646	0.0213200	0.0157370
umls:C0007113	Rectal Carcinoma	221	1.492276	0.0311509	0.0229935
umls:C0024668	Mammary Neoplasms, Experimental	185	1.486728	0.0402861	0.0297365
umls:C1271104	Blood pressure finding	330	1.484275	0.0213200	0.0157370
umls:C0494165	Secondary malignant neoplasm of liver	349	1.480810	0.0213200	0.0157370
umls:C0027022	Myeloproliferative disease	216	1.467439	0.0465262	0.0343425
umls:C0007138	Carcinoma, Transitional Cell	332	1.461678	0.0213200	0.0157370
umls:C0032580	Adenomatous Polyposis Coli	324	1.456559	0.0213200	0.0157370
umls:C0032584	polyps	206	1.450466	0.0463533	0.0342149
umls:C0021400	Influenza	374	1.447931	0.0213200	0.0157370
umls:C0007193	Cardiomyopathy, Dilated	328	1.436125	0.0295915	0.0218425
umls:C0040136	Thyroid Neoplasm	397	1.435965	0.0213200	0.0157370
umls:C1704272	Benign Prostatic Hyperplasia	301	1.435475	0.0301940	0.0222872
umls:C0555198	Malignant Glioma	356	1.435058	0.0294219	0.0217173
umls:C1709246	Non-Neoplastic Disorder	374	1.429963	0.0213200	0.0157370
umls:C0015695	Fatty Liver	286	1.428683	0.0306953	0.0226572
umls:C1512409	Hepatocarcinogenesis	399	1.423309	0.0213200	0.0157370
umls:C0035309	Retinal Diseases	289	1.416967	0.0440414	0.0325084
umls:C1520166	Xenograft Model	440	1.408263	0.0213200	0.0157370
umls:C0035078	Kidney Failure	268	1.404060	0.0458797	0.0338653
umls:C0020456	Hyperglycemia	380	1.397997	0.0213200	0.0157370
umls:C0041296	Tuberculosis	427	1.394137	0.0213200	0.0157370
umls:C0036690	Septicemia	304	1.393012	0.0438335	0.0323550
umls:C0007115	Malignant neoplasm of thyroid	393	1.342035	0.0427786	0.0315763
umls:C0035335	Retinoblastoma	388	1.328727	0.0489743	0.0361495

Enriched terms for module #84AD00 (MTcor = -0.93)

ID	Description	setSize	NES	p.adjust	qvalues
umls:C0543888	Epileptic encephalopathy	51	2.482362	0.0356247	0.0281029
umls:C0342776	Nicotinamide adenine dinucleotide coenzyme Q reductase deficiency	38	2.432047	0.0356247	0.0281029
umls:C1838979	MITOCHONDRIAL COMPLEX I DEFICIENCY	29	2.429053	0.0356247	0.0281029
umls:C0037769	West Syndrome	58	2.325541	0.0356247	0.0281029
umls:C2936907	NADH:Q(1) Oxidoreductase deficiency	20	2.180142	0.0356247	0.0281029
umls:C0014550	Epilepsies, Myoclonic	36	2.170404	0.0356247	0.0281029
umls:C0238111	Lennox-Gastaut syndrome	11	2.136084	0.0356247	0.0281029
umls:C0751122	Infantile Severe Myoclonic Epilepsy	25	2.113278	0.0356247	0.0281029
umls:C0393706	Early infantile epileptic encephalopathy with suppression bursts	19	2.092171	0.0356247	0.0281029
umls:C0017926	Glycogen Storage Disease Type VII	11	2.087134	0.0356247	0.0281029
umls:C1838951	LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY	14	2.084908	0.0356247	0.0281029
umls:C0023264	Leigh Disease	77	2.058937	0.0356247	0.0281029
umls:C0085292	Stiff-Person Syndrome	19	2.057038	0.0356247	0.0281029
umls:C2931919	X-linked infantile spasm syndrome	15	2.048455	0.0356247	0.0281029
umls:C1849156	Spastic Ataxia	14	2.040328	0.0356247	0.0281029
umls:C0406810	Carney Complex	27	2.025996	0.0493656	0.0389425
umls:C0029124	Optic Atrophy	31	1.993882	0.0356247	0.0281029
umls:C0342492	Adrenal hypertrophy or hyperplasia	17	1.985649	0.0356247	0.0281029
umls:C1621895	Adrenal hyperplasia	17	1.985649	0.0356247	0.0281029
umls:C0162670	Mitochondrial Myopathies	48	1.982734	0.0356247	0.0281029
umls:C0014547	Epilepsies, Partial	42	1.967555	0.0356247	0.0281029
umls:C0026650	Movement Disorders	95	1.964739	0.0356247	0.0281029
umls:C1142166	Brugada Syndrome (disorder)	46	1.920346	0.0356247	0.0281029
umls:C0162674	Chronic progressive external ophthalmoplegia	19	1.911793	0.0493656	0.0389425
umls:C0004134	Ataxia	221	1.879095	0.0356247	0.0281029
umls:C0424551	Impaired exercise tolerance	27	1.854635	0.0493656	0.0389425
umls:C0014548	Epilepsy, Generalized	44	1.788307	0.0493656	0.0389425
umls:C0162666	Mitochondrial Encephalomyopathies	32	1.773487	0.0493656	0.0389425
umls:C0270850	Idiopathic generalized epilepsy	45	1.768474	0.0493656	0.0389425
umls:C1096063	Drug Resistant Epilepsy	53	1.758148	0.0356247	0.0281029
umls:C1955869	Malformations of Cortical Development	45	1.748752	0.0493656	0.0389425
umls:C0270736	Essential Tremor	49	1.746995	0.0493656	0.0389425
umls:C0278484	Malignant neoplasm of colon stage IV	62	1.732129	0.0493656	0.0389425
umls:C0035372	Rett Syndrome	111	1.687489	0.0493656	0.0389425
umls:C0026827	Muscle hypotonia	73	1.671249	0.0493656	0.0389425
umls:C0525045	Mood Disorders	238	1.632827	0.0356247	0.0281029
umls:C0027765	nervous system disorder	388	1.457565	0.0493656	0.0389425

rm(df)